Identifiers and Description

Gene Model Identifier

TTHERM_00492850

Standard Name

ilsA (IsoLeucine-tRNA Synthetase )

Aliases

PreTt04221 | 61.m00208 | cupC | 3711.m00056

Description

Isoleucyl-tRNA synthetase; contains two C-terminal leucine zipper motifs and sequence similarity with the S.cerevisiae ileRS protein; transcript induced during meitoic prophase and nutritional shift-up but decreased by starvation

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

TetraMine Data

TTHERM_00492850

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Stentor CoeruleusSteCoe_97950
WormBaseWBGene000021529.997093137033517e-262locus:iars-1 Isoleucine--tRN
A ligase, cytoplasmic status
:Partially_confirmed UniProt
:Q21926 protein_id:CAA94369.
1
Tetrahymena borealisEI9_12981.19.997093137033517e-262isoleucyl-tRNA synthetase (110
1 aa)
DictyBaseDDB_G02782939.997093137033517e-262ileS on chromosome: 3 position
632971 to 636359
OxytrichaContig21964.0.g219.997093137033517e-262tRNA synthetases class I (I, L
, M and V)
SGDYBL076C9.997093137033517e-262ILS1 Cytoplasmic isoleucine-tR
NA synthetase, target of the G
1-specific inhibitor reveromyc
in A

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:1371507: Csank C, Martindale DW (1992) Isoleucyl-tRNA synthetase from the ciliated protozoan Tetrahymena thermophila. DNA sequence, gene regulation, and leucine zipper motifs. The Journal of biological chemistry 267(7):4592-9
  2. Ref:2663194: Martindale DW, Gu ZM, Csank C (1989) Isolation and complete sequence of the yeast isoleucyl-tRNA synthetase gene (ILS1). Current genetics 15(2):99-106
  3. Ref:3005971: Martindale DW, Martindale HM, Bruns PJ (1986) Tetrahymena conjugation-induced genes: structure and organization in macro- and micronuclei. Nucleic acids research 14(3):1341-54
  4. Ref:6646127: Martindale DW, Bruns PJ (1983) Cloning of abundant mRNA species present during conjugation of Tetrahymena thermophila: identification of mRNA species present exclusively during meiosis. Molecular and cellular biology 3(10):1857-65

Sequences

>TTHERM_00492850(coding)
ATGATTCTTTTCAAAAAATTATTAATATAAAAAAAAGTAAATTATCTAAGCAGATTATTA
ATGGCTTCAAAGACCACCTTCAAAGATCTTTAGGAAATTCCTGATTTCCCTAAGGAAGAA
GAGAACATCCTCAAGTTTTGGGATGAAATTAATGCTTTTAAGCAACAATTAGAAAAAACT
AAGGATTGCCCTCCTTTCACTTTCTACGATGGCCCACCATTCGCTACCGGTTTACCTCAC
TATGGTAACCTTCTTGCTGGTACAATCAAGGATGTCGTTTGCAGATACGCTTCTCAAAAT
GGCAAATATGTTGAAAGAAGATTCGGTTGGGATTGTCACGGTCTTCCAGTTGAATATGAA
ATCGATAAGAAGCTCGGTATCACCAATAGACAAGAAGTCTTAAAGATGGGTGTCGACAAG
TACAATGCTGAATGCCGTAGCATCGTCATGAGATACGCTTAAGAATGGAGATCAATCGTG
AACAGATTTGGTCGTTGGGTTGACTTTGACAATGATTACAAAACTCTTGATTTGAAGTTT
ATGGAATCCGTTTGGTGGGTTTTCAAGCAAATGTTCGATAAGGGATTAGTTTATAGAGGT
TGCAAGGTTATGCCCTACTCCAATGGTTGTGCAACTGTCTTATCTAACTTCGAAACTCAA
CAAAACTACAAGGAAGTTGATGATCCTTCTCTCTTCATCGCTTTTAAGACTGCCGAAGAT
CCTAAGACCAAGTTCATTGCTTGGACAACCACTCCTTGGACACTTCCTTCTAACTTGGCT
TTGGTTATCAACAAGGACTTCGATTACGTTAAGGTTTTAGATGCTAAGACCTAAGAACAC
TACATTCTTGCAGAATGCCGTCTCCCTGAATTATACAAAAAGGATAAGGATGGATACAAG
ATCTTAGAAAAATTCAAAGGTTCTGAACTCGTAGGCAGAGAATATGAACCTCTTTTCCCC
TATTTCCTCTCTAGAAAGCAAGATGGCTGCTTCAGAATTCTCGCTGGTGACTTCGTTACT
GCTGATGCTGGTACTGGTATCGTCCACTGCGCCCCTGGTTTTGGTGATGACGATTACAAA
GTCTCAGTTGCAAATAACATCATCAAGCCCGATGATCCACCCGTACCTGTTGATGAAAAC
GGTCATTTCACTAATGTCGTTTCTGATTTTGCTGGTGTTTACATCAAGGAAGCTGATAAG
TTAATTAGAAAGAACTTGAAGGAAAGAGGTTTGTTGCTCGTTGATTCTTCATTCAAGCAC
AACTATCCCTTCTGCTGGAGATCTGATACCCCCTTGATTTACAAGGCTGTTCACTGCTGG
TTCATTAAGGTTACTGCCCTTAAGGATGACCTTTTAGCTAACAACAAGAAGGCTTATTGG
GTTCCTAAATTTGCTTAAGAAGGACGTTTCAACAACTGGTTGTAGAATGTCTCTGATTGG
TGTTTCTCTAGATCTAGATTCTGGGGTAACCCTATCCCTATTTGGGTTTCTGAAGATTTT
GAAGAAGTTGTTTGCATTGGATCAGTTGAAGAACTCAAGAAATTAACTGGTGCAACTGAA
ATCACTGATTTACACAAAGATTTTATTGATCACCTTACCATCCCATCCTAAAAGGGTAAG
GGGGTCTTAAGACGTATTGATGAAGTCTTTGATTGCTGGTTCGAATCTGGTTCTATGCCT
TATGGTCAATAACACTATCCCTTCTCTATGAACGAAGAAGAGTTCTCTAAGAGATTCCCT
GCTGATTTCATCGGTGAAGGTATTGATCAAACTAGAGGTTGGTTCTATACTCTTAACGTT
ATTTCTACTGCCTTAAGAAATTCCAACCCCTACAAAAACCTTATTGTTAACGGTATCGTT
CTTGCTGCTGACGGAAAGAAGATGTCTAAGTCAAAGAAGAACTACGATGATCCCTTGCTC
ATTGCCTCCAAGTACTCCGTTGATGCTATCCGTTTATATATGATCAACTCTCCTTTAGTC
AGAGCTGAAGAAATGAGTTTCAAGTCCGAAGGTGTTTTTGCTGTTAAGAAAGATATCTTC
TTACCCTGGTACAATGCTTACAAATTCTTAATCTAAAGTATCACTAGATGGGAACTCGCT
ACTGGAAAAGACTACATGTTCAACGAACAACTCTCTGTTGATACTACTAAATTAACTAAT
CCTACTGATAGATGGATTATTATCTCCTGCCAAAACTTGATCAACTATGTCAGAATTGAA
ATGGAAAAGTATCACTTGTACAATGTCGTTCCTCGTTTAATCCACTTCTTAGAAAACTTA
ACCAACTGGTATATTAGATTAAACAGAAACAGACTAAAAGGTGATTACGGTCTTGAAGAA
TAAGAAACTTCCCTCAACGTCTTATTCAACGTTATCTTAAACTCCACTATTTTAATGTCA
CCTTTAGTTCCTTTCATCACTGAAAGTTTCTATCAAAACTTAAGAAAGGTCATTCCTAAG
GGTTCTTCTTACTTAGAAGAATCTATCCACTTCTTGAGAATCCCTACTCCTAAGCAAGAA
CTTCTCGATGAAAAGATCGAAAGAAACTTTGAAAGAATGTAAAACATCATCAACTTTGCT
CGTACTTTAAGAGAAAAGAGAAAGGTCTCTCTTAAGCAACCTATCATGTCTTTGACTGTC
ATCAATTAAGACTAAGAATTCCACGATTCCTTAAAGGATTACATTCAATATATTGAAGAT
GAAATCAACACTCCTTCTATCCTCCACGAAATTAACACTGCTAATTATGTTGACTTAAAG
GCCATTCCTAATCACAAACTCCTTGGACAAAAACTTGGTAAGGAATACAATAAGGATCTT
AAGGCTGCTGCCGGTAACTTGTCTGCCAAGGATATTGAAACCTTGAAGACTACTGGATCT
ATTGATTTAGTTGGCAAGAAATTACTTTTGGAAGACTTCACCATTACTCAAAATTACAAG
AAAGAATACTCTAGTGGTGACTTAGAACTTGGTGGTGAAGGTGAAGTTATTTTACTTTTG
AACCTCGCTCAAGATGAAAAGTTAAAGAGCAAAGGTCTTGTTAGAGAATTTACCAGCAAC
GTTTAAAAGACCAAGAAGAAAACCGGCTTAAAGGTTGACGATAACATCGTTATTTATTAT
GATGTTACCAAAGCACCCAAGTTAAATGCTGCTATTTAATCCGATTTAGAAGCTGTCCAA
AAGGTCTTAAAGAAACCCCTCGTTCCTTTATCTGAAAAGAATGCTGCTCTTAAGATTGTT
GAAAACTCTTTACTTACTTTCTAGGTTGATGAAGAATCCGTTACTATCGAAATCGCTTAT
GCTTGA


>TTHERM_00492850(protein)
MILFKKLLIQKKVNYLSRLLMASKTTFKDLQEIPDFPKEEENILKFWDEINAFKQQLEKT
KDCPPFTFYDGPPFATGLPHYGNLLAGTIKDVVCRYASQNGKYVERRFGWDCHGLPVEYE
IDKKLGITNRQEVLKMGVDKYNAECRSIVMRYAQEWRSIVNRFGRWVDFDNDYKTLDLKF
MESVWWVFKQMFDKGLVYRGCKVMPYSNGCATVLSNFETQQNYKEVDDPSLFIAFKTAED
PKTKFIAWTTTPWTLPSNLALVINKDFDYVKVLDAKTQEHYILAECRLPELYKKDKDGYK
ILEKFKGSELVGREYEPLFPYFLSRKQDGCFRILAGDFVTADAGTGIVHCAPGFGDDDYK
VSVANNIIKPDDPPVPVDENGHFTNVVSDFAGVYIKEADKLIRKNLKERGLLLVDSSFKH
NYPFCWRSDTPLIYKAVHCWFIKVTALKDDLLANNKKAYWVPKFAQEGRFNNWLQNVSDW
CFSRSRFWGNPIPIWVSEDFEEVVCIGSVEELKKLTGATEITDLHKDFIDHLTIPSQKGK
GVLRRIDEVFDCWFESGSMPYGQQHYPFSMNEEEFSKRFPADFIGEGIDQTRGWFYTLNV
ISTALRNSNPYKNLIVNGIVLAADGKKMSKSKKNYDDPLLIASKYSVDAIRLYMINSPLV
RAEEMSFKSEGVFAVKKDIFLPWYNAYKFLIQSITRWELATGKDYMFNEQLSVDTTKLTN
PTDRWIIISCQNLINYVRIEMEKYHLYNVVPRLIHFLENLTNWYIRLNRNRLKGDYGLEE
QETSLNVLFNVILNSTILMSPLVPFITESFYQNLRKVIPKGSSYLEESIHFLRIPTPKQE
LLDEKIERNFERMQNIINFARTLREKRKVSLKQPIMSLTVINQDQEFHDSLKDYIQYIED
EINTPSILHEINTANYVDLKAIPNHKLLGQKLGKEYNKDLKAAAGNLSAKDIETLKTTGS
IDLVGKKLLLEDFTITQNYKKEYSSGDLELGGEGEVILLLNLAQDEKLKSKGLVREFTSN
VQKTKKKTGLKVDDNIVIYYDVTKAPKLNAAIQSDLEAVQKVLKKPLVPLSEKNAALKIV
ENSLLTFQVDEESVTIEIAYA


>TTHERM_00492850(gene)
TAAATAAATTATCTATTTCGAAAAAGAAGAATATTTGAAAAGATAGCCCAGAAAAGGAGA
AACTAACAATATCTTATAATTAAATTTATGATTCTTTTCAAAAAATTATTAATATAAAAA
AAAGTAAATTATCTAAGCAGATTATTAATGGCTTCAAAGACCACCTTCAAAGATCGTAAT
AATTACTTCTACTAATAAATATGCCTTTTTCTATGAAAAACAAAATCTATAAATGTCCTA
GAAATTAATATTTTCTTTTAATACTCATATAGTTTAGGAAATTCCTGATTTCCCTAAGGA
AGAAGAGAACATCCTCAAGTTTTGGGATGAAATTAATGCTTTTAAGCAACAATTAGAAAA
AACTAAGGATTGCCCTCCTTTCACTTTCTACGATGGCCCACCATTCGCTACCGGTTTACC
TCACTATGGTAACCTTCTTGCTGGTACAATCAAGGTATTTTATAAAAATTTTTATTTATT
TCAGAAAATTCTATTTAGTTTTTTGCTCTTGCCATGTTTATTTTTCTGAAATAAAATCCT
GTGTACGAAAAAAAAAAAACAAATTGACTAAAATAATTATTTTATTGGAGTCAACACATT
TTTTTTTTCATTTTTTAAACTTAAACTGTTTCTGAATTACTTAAATAAATAATATTAATA
TATTTTTAAATGCTTATAGGATGTCGTTTGCAGATACGCTTCTCAAAATGGCAAATATGT
TGAAAGAAGATTCGGTTGGGATTGTCACGGTCTTCCAGTTGAATATGAAATCGATAAGAA
GCTCGGTATCACCAATAGACAAGAAGTCTTAAAGGTAATATTTAAGATAAAAATTAGCAT
TTTTAGTTAATTCGAACCCTAATTTGGCATTAGATATATTTCGAATACCATATTTTGCAA
AGATGAAAATATTCAATTAAATTAAGCTTTTGAAAGTTTAATTAATAAATAGATACAGAA
TAATAAATAAAGTATAAATCTTAGAAAAAATTGGCGCAACTTCAATTAAAAAAAAAATTT
TCATTCTTTTTTTTAAACAAAATATAATTTTCTTACTCTAATAAATCTTAAATAGAAATA
CATTTAATCTAAAAAATTATTTATTTTTATATTAGATGGGTGTCGACAAGTACAATGCTG
AATGCCGTAGCATCGTCATGAGATACGCTTAAGAATGGAGATCAATCGTGAACAGATTTG
GTCGGTAATGAAACTTCCTATTTAAATATCTTCTTTAATTAAAATAAATTATTAATTCTA
ATTCAATAAATAAGAAAGGAAAATAACTAACGAATTAGCTTTTTAAATAAGCAAAGAAAA
ATTAAAATTTTAAAAACATAATTAATTATAGAAAATATAAATTTAATTCAATATTTATTA
ATTAATTATATTATAGTTGGGTTGACTTTGACAATGATTACAAAACTCTTGATTTGAAGT
TTATGGAATCCGTTTGGTGGGTTTTCAAGCAAATGTTCGATAAGGGATTAGTTTATAGAG
GTTGCAAGGTTATGCCCTACTCCAATGGTTGTGCAACTGTCTTATCTAACTTCGAAACTC
AACAAAACTACAAGGAAGTTGATGATCCTTCTCTCTTCATCGCTTTTAAGACTGCCGAAG
ATCCTAAGACCAAGTTCATTGCTTGGACAACCACTCCTTGGACACTTCCTTCTAACTTGG
CTTTGGTTATCAACAAGGACTTCGATTACGTTAAGGTTTTAGATGCTAAGACCTAAGAAC
ACTACATTCTTGCAGAATGCCGTCTCCCTGAATTATACAAAAAGGATAAGGATGGATACA
AGATCTTAGAAAAATTCAAAGGTTCTGAACTCGTAGGCAGAGAATATGAACCTCTTTTCC
CCTATTTCCTCTCTAGAAAGCAAGATGGCTGCTTCAGAATTCTCGCTGGTGACTTCGTTA
CTGCTGATGCTGGTACTGGTATCGTCCACTGCGCCCCTGGTTTTGGTGATGACGATTACA
AAGTCTCAGTTGCAAATAACATCATCAAGCCCGATGATCCACCCGTACCTGTTGATGAAA
ACGGTCATTTCACTAATGTCGTTTCTGATTTTGCTGGTGTTTACATCAAGGAAGCTGATA
AGTTAATTAGAAAGAACTTGAAGGAAAGAGGTTTGTTGCTCGTTGATTCTTCATTCAAGC
ACAACTATCCCTTCTGCTGGAGATCTGATACCCCCTTGATTTACAAGGCTGTTCACTGCT
GGTTCATTAAGGTTACTGCCCTTAAGGATGACCTTTTAGCTAACAACAAGAAGGCTTATT
GGGTAATTATTTAGATTGACATTTAAAAATATTATTTTACTTAAATTATTCCAAATATAT
TAATTAGGTTCCTAAATTTGCTTAAGAAGGACGTTTCAACAACTGGTTGTAGAATGTCTC
TGATTGGTGTTTCTCTAGATCTAGATTCTGGGGTAACCCTATCCCTATTTGGGTTTCTGA
AGATTTTGAAGAAGTTGTTTGCATTGGATCAGTTGAAGAACTCAAGAAATTAACTGGTGC
AACTGAAATCACTGATTTACACAAAGATTTTATTGATCACCTTACCATCCCATCCTAAAA
GGGTAAGGGGGTCTTAAGACGTATTGATGAAGTCTTTGATTGCTGGTTCGAATCTGGTTC
TATGCCTTATGGTCAATAACACTATCCCTTCTCTATGAACGAAGAAGAGTTCTCTAAGAG
ATTCCCTGCTGATTTCATCGGTGAAGGTATTGATCAAACTAGAGGTTGGTTCTATACTCT
TAACGTTATTTCTACTGCCTTAAGAAATTCCAACCCCTACAAAAACCTTATTGTTAACGG
TATCGTTCTTGCTGCTGACGGAAAGAAGATGTCTAAGTCAAAGAAGAACTACGATGATCC
CTTGCTCATTGCCTCCAAGTACTCCGTTGATGCTATCCGTTTATATATGGTATTTATTTT
CTTCTTTTAATAAAACCAAATTAATCATTTTAATTCCTTATCCTAAAGATCAACTCTCCT
TTAGTCAGAGCTGAAGAAATGAGTTTCAAGTCCGAAGGTGTTTTTGCTGTTAAGAAAGAT
ATCTTCTTACCCTGGTACAATGCTTACAAATTCTTAATCTAAAGTATCACTAGATGGGAA
CTCGCTACTGGAAAAGACTACATGTTCAACGAACAACTCTCTGTTGATACTACTAAATTA
ACTAATCCTACTGATAGATGGATTATTGTAAGAATATTAAAATAGCTATTTTTTAATTTT
AAAACAACTTTTACAAATAGATCTCCTGCCAAAACTTGATCAACTATGTCAGAATTGAAA
TGGAAAAGTATCACTTGTACAATGTCGTTCCTCGTTTAATCCACTTCTTAGAAAACTTAA
CCAACTGGTATATTAGATTAAACAGAAACAGACTAAAAGGTGATTACGGTCTTGAAGAAT
AAGAAACTTCCCTCAACGTCTTATTCAACGTTATCTTAAACTCCACTATTTTAATGTCAC
CTTTAGTTCCTTTCATCACTGAAAGTTTCTATCAAAACTTAAGAAAGGTCATTCCTAAGG
GTTCTTCTTACTTAGAAGAATCTATCCACTTCTTGAGAATCCCTACTCCTAAGCAAGAAC
TTCTCGATGAAAAGATCGAAAGAAACTTTGAAAGAATGTAAAACATCATCAACTTTGCTC
GTACTTTAAGAGAAAAGAGAAAGGTCTCTCTTAAGCAACCTATCATGGTAATATTCAACA
ATTTATTATTATTATTAATGGTAATTAATTTTTAAAATCAAAGTCTTTGACTGTCATCAA
TTAAGACTAAGAATTCCACGATTCCTTAAAGGATTACATTCAATATATTGAAGATGAAAT
CAACACTCCTTCTATCCTCCACGAAATTAACACTGCTAATTATGTTGACTTAAAGGCCAT
TCCTAATCACAAACTCCTTGGACAAAAACTTGGTAAGGAATACAATAAGGATCTTAAGGC
TGCTGCCGGTAACTTGTCTGCCAAGGATATTGAAACCTTGAAGACTACTGGATCTATTGA
TTTAGTTGGCAAGAAATTACTTTTGGAAGACTTCACCATTACTCAAAATTACAAGAAAGA
ATACTCTAGTGGTGACTTAGAACTTGGTGGTGAAGGTGAAGTTATTTTACTTTTGAACCT
CGCTCAAGATGAAAAGTTAAAGAGCAAAGGTCTTGTTAGAGAATTTACCAGCAACGTTTA
AAAGACCAAGAAGAAAACCGGCTTAAAGGTTGACGATAACATCGTTATTTATTATGATGT
TACCAAAGCACCCAAGTTAAATGCTGCTATTTAATCCGATTTAGAAGCTGTCCAAAAGGT
CTTAAAGAAACCCCTCGTTCCTTTATCTGAAAAGAATGCTGCTCTTAAGATTGTTGAAAA
CTCTTTACTTACTTTCTAGGTTGATGAAGAATCCGTTACTATCGAAATCGCTTATGCTTG
AAAGATATTCTATTTAATAAACAATACTATGATTTTTTTTTTATTTAATATGATTACTAA
ACATTTAATTTATAATTAAAAACTATCTTTCTTTCTACCTATTTTTCTGTCTGTTTGTTA
GTCTACATTTCTATTTTGTAGATTTACTTCAATTTTTTAAATTTTAAATAAATAAC