Identifiers and Description

Gene Model Identifier

TTHERM_00522720

Standard Name

UBC9 (Ubiquitin conjugating enzyme 9)

Aliases

PreTt12387 | 65.m00205 | 3717.m00084

Description

SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; a member of the ubiquitin-conjugating enzyme E2 family

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ubiquitin-like protein transferase activity (IEA) | GO:0019787

Biological Process

• regulation of protein metabolic process (IEA) | GO:0051246
• post-translational protein modification (IEA) | GO:0043687

Domains

• ( PF00179 ) Ubiquitin-conjugating enzyme

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00522720

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_12835.1	2.0009580008310955e-119	ubiquitin-conjugating enzyme f amily protein (168 aa)
Oxytricha	Contig20855.0.g27	9.999353957415832e-59	Ubiquitin-conjugating enzyme
DictyBase	DDB_G0287693	9.997652352281279e-57	ubc9 on chromosome: 5 position 688286 to 689217
WormBase	WBGene00006706	6.997794455893953e-54	locus:ubc-9 SUMO-conjugating enzyme UBC9 status:Confirme d UniProt:Q95017 protein_i d:CCD70229.1
SGD	YDL064W	9.998397555368434e-52	UBC9 SUMO-conjugating enzyme i nvolved in the Smt3p conjugati on pathway; nuclear protein re quired for S- and M-phase cycl in degradation and mitotic con trol; involved in proteolysis mediated by the anaphase-promo ting complex cyclosome (APCC)
Stentor Coeruleus	SteCoe_14361	5.900090541597061e-29

General Information

No Data fetched for General Information

Associated Literature

1. Ref:26453653: Yang Q, Nasir AM, Coyne RS, Forney JD (2015) Depletion of UBC9 Causes Nuclear Defects during the Vegetative and Sexual Life Cycles in Tetrahymena thermophila. Eukaryotic cell 14(12):1240-52

Sequences

>TTHERM_00522720(coding)
ATGTAGCAACAAAATAAAGAAGTAAATGAATTAGTTATTACTAGACTAAAATAGGAAAGA
AAGCAATGGCGTCAAGATCATCCTCACAGATTTGTAGCAAAACCCATGACCAAAGAAGAT
GGAACTATCAATATGCTTAAATGGTATTGCGAAATTCCTGGACCAGAAGGCAGTCCATGG
GAAGGTGGTGTTTATATTTTATATATGGATTTCTCTCAATCCTATCCTATAAAGCCTCCT
AAATGTCAATTTAAGCCTGTCCTTCCTCACCCTAATGTCTATCCTTCAGGAACTGTGTGT
CTTTCTATATTAAATGAGGAAGAAGATTGGAAATCAGCTATAACTATTAAATAGATTTTG
ATGGGTATATAAAAATTATTAAAAGATGAGCCTAATATTGATAGTCCTGCTTAATACGAA
CCTTGCGCTCTTTACAGGAGTGATAAAGAAAAATACTATAAAAAAGTAAGAGAATTTGCT
GAAACCATGAAAAAAAAAGACTGA

>TTHERM_00522720(protein)
MQQQNKEVNELVITRLKQERKQWRQDHPHRFVAKPMTKEDGTINMLKWYCEIPGPEGSPW
EGGVYILYMDFSQSYPIKPPKCQFKPVLPHPNVYPSGTVCLSILNEEEDWKSAITIKQIL
MGIQKLLKDEPNIDSPAQYEPCALYRSDKEKYYKKVREFAETMKKKD

>TTHERM_00522720(gene)
ATGTAGCAACAAAATAAAGAAGTAAATGAATTAGTTATTACTAGACTAAAATAGGAAAGA
AAGCAATGGCGTCAAGATCATCCTCACGTAATAATTATTAGTGATTGATTCTTTCTTCAT
TTATCGATTGATAAATGGATGAAGAATAGCAAGCTTGCGTACAATTCGATTCAACAGATA
TTCTTATATTTCATCTATTTAATAAAAATAGAGATTTGTAGCAAAACCCATGACCAAAGA
AGATGGAACTATCAATATGCTTAAATGGTATTGCGAAATTCCTGGACCAGAAGGCGTAAA
AAACCATTTAATTTTTAAAAACTCTTAGATTTCATTTAAAAAAAAAAAAATTGTTAAAAA
TTAACTTTTAAATCAAAAATAATAATTTTTGCGGCATTTCTAATCTATAATACAAAATAA
TATAAAAAATAAAAATAATAATACTAATATATAATAGAGTCCATGGGAAGGTGGTGTTTA
TATTTTATATATGGATTTCTCTCAATCCTATCCTATAAAGCCTCCTAAATGTAAATTAAT
ATATTTGCTAATTAAGTTAGTTATTTTTAATAAATTTAATTTTCTGATGATTAGGTCAAT
TTAAGCCTGTCCTTCCTCACCCTAATGTCTATCCTTCAGGTATTTTAAATATTTAATATA
GTTTTATTTTATAGCAAACTATATTTATGACTTTATTAATTATAAATAAAATTTATTACC
TTAAAATAAGGAACTGTGTGTCTTTCTATATTAAATGAGGAAGAAGATTGGAAATCAGCT
ATAACTATTAAATAGATTTTGATGGGTATATAAAAATTATTAAAAGATGAGCCTAATATT
GATAGTCCTGCTTAATACGAACCTTGCGCTCTTTACAGGTAAACTTAAAAAAAATAAAAA
TTTATTAAAGGAAAATATTATTATTTACAATAGGAGTGATAAAGAAAAATACTATAAAAA
AGTAAGAGAATTTGCTGAAACCATGAAAAAAAAAGACTGA