Identifiers and Description

Gene Model Identifier

TTHERM_00077240

Standard Name

TTU3 (Tetrahymena Thermophila polyUbiquitin 3)

Aliases

PreTt10070 | 5.m00421 | 3828.m01331

Description

Polyubiquitin; gene encodes five identical, tandem Ub units; full-length transcript levels increase under hyperthermic stress conditions

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein tag (ISS) | GO:0031386 | Ref:8982086

Biological Process

• protein ubiquitination (ISS) | GO:0016567 | Ref:8982086
• conjugation with mutual genetic exchange (IEP) | GO:0000748 | Ref:8982086

Domains

• ( PF00240 ) Ubiquitin family
• ( TIGR00601 ) UV excision repair protein Rad23

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 14.5%

TetraMine Data

TTHERM_00077240

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_24295	0
WormBase	WBGene00006727	9.997093137033517e-262	locus:ubq-1 status:Confirmed UniProt:G8JY83 protein_id :CCD68780.1
DictyBase	DDB_G0282369	9.997093137033517e-262	ubqG on chromosome: 3 position 5878544 to 5879689
Oxytricha	Contig8023.0.g94	9.997093137033517e-262	Ubiquitin family
SGD	YLL039C	9.997093137033517e-262	UBI4 Ubiquitin, becomes conjug ated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cell ular stress response; encoded as a polyubiquitin precursor c omprised of 5 head-to-tail rep eats
Tetrahymena borealis	EI9_14651.1	3.998941839720987e-159	ubiquitin family protein (231 aa)

General Information

No Data fetched for General Information

Associated Literature

1. Ref:8982086: Guerreiro P, Rodrigues-Pousada C (1996) Characterization of a polyubiquitin gene in T. thermophila and of ubiquitin gene expression during sexual reproduction and under stress conditions. Gene 182(1-2):183-8
2. Ref:SUPR000251

Sequences

>TTHERM_00077240(coding)
ATGCAAATCTTCGTTAAGACCCTTACTGGTAAAACCATTACTTTAGACGTTGAAGCCTCC
GACACTATTGAAAACGTCAAGGCTAAGATTCAAGACAAGGAAGGTATCCCTCCTGATCAA
TAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTTTCTGACTACAAC
ATTCAAAAGGAATCAACCCTCCACTTGGTTTTAAGATTAAGAGGTGGTATGCAAATTTTC
GTCAAGACCTTGACTGGTAAGACCATCACTCTTGACGTTGAAGCCTCTGACACTATTGAA
AACGTCAAGGCTAAGATCCAAGACAAGGAAGGTATCCCCCCTGATCAATAAAGACTTATC
TTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTTTCTGACTACAACATCCAAAAGGAA
TCTACCCTCCACTTAGTCCTCAGATTAAGAGGTGGTATGTAAATCTTCGTCAAGACCTTA
ACTGGCAAGACCATCACTCTTGATGTTGAAGCCTCCGACACCATTGAAAATGTCAAGGCT
AAGATCTAAGACAAGGAAGGTATCCCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAG
CAATTAGAAGACGGCAGAACCCTTTCTGACTACAACATCCAAAAGGAATCTACTCTCCAC
TTAGTCCTTAGATTGAGAGGTGGTATGTAAATCTTCGTCAAGACCTTAACTGGCAAGACC
ATCACTCTTGATGTCGAAGCTTCTGACACCATTGAAAACGTCAAGGCTAAGATCCAAGAC
AAGGAAGGTATCCCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGAC
GGCAGAACCCTTTCTGACTACAACATTCAAAAGGAATCAACCCTCCACTTGGTTTTAAGA
TTAAGAGGTGGTATGCAAATTTTCGTCAAGACCTTGACTGGTAAGACCATCACTCTTGAC
GTTGAAGCCTCTGACACTATTGAAAACGTCAAGGCTAAGATCCAAGACAAGGAAGGTATC
CCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTT
TCTGACTACAACATCCAAAAGGAATCTACCCTCCACTTAGTCCTCAGATTAAGAGGTGGT
TTCTGA

>TTHERM_00077240(protein)
MQIFVKTLTGKTITLDVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEASDTIENVKAKIQDKEGIPPDQQRLI
FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEASDTIENVKA
KIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLDVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLDVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
SDYNIQKESTLHLVLRLRGGF

>TTHERM_00077240(gene)
ATGCAAATCTTCGTTAAGACCCTTACTGGTAAAACCATTACTTTAGACGTTGAAGCCTCC
GACACTATTGAAAACGTCAAGGCTAAGATTCAAGACAAGGAAGGTATCCCTCCTGATCAA
TAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTTTCTGACTACAAC
ATTCAAAAGGAATCAACCCTCCACTTGGTTTTAAGATTAAGAGGTGGTATGCAAATTTTC
GTCAAGACCTTGACTGGTAAGACCATCACTCTTGACGTTGAAGCCTCTGACACTATTGAA
AACGTCAAGGCTAAGATCCAAGACAAGGAAGGTATCCCCCCTGATCAATAAAGACTTATC
TTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTTTCTGACTACAACATCCAAAAGGAA
TCTACCCTCCACTTAGTCCTCAGATTAAGAGGTGGTATGTAAATCTTCGTCAAGACCTTA
ACTGGCAAGACCATCACTCTTGATGTTGAAGCCTCCGACACCATTGAAAATGTCAAGGCT
AAGATCTAAGACAAGGAAGGTATCCCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAG
CAATTAGAAGACGGCAGAACCCTTTCTGACTACAACATCCAAAAGGAATCTACTCTCCAC
TTAGTCCTTAGATTGAGAGGTGGTATGTAAATCTTCGTCAAGACCTTAACTGGCAAGACC
ATCACTCTTGATGTCGAAGCTTCTGACACCATTGAAAACGTCAAGGCTAAGATCCAAGAC
AAGGAAGGTATCCCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGAC
GGCAGAACCCTTTCTGACTACAACATTCAAAAGGAATCAACCCTCCACTTGGTTTTAAGA
TTAAGAGGTGGTATGCAAATTTTCGTCAAGACCTTGACTGGTAAGACCATCACTCTTGAC
GTTGAAGCCTCTGACACTATTGAAAACGTCAAGGCTAAGATCCAAGACAAGGAAGGTATC
CCCCCTGATCAATAAAGACTTATCTTCGCTGGTAAGCAATTAGAAGACGGCAGAACCCTT
TCTGACTACAACATCCAAAAGGAATCTACCCTCCACTTAGTCCTCAGATTAAGAGGTGGT
TTCTGA