Gene Model Identifier
TTHERM_01169510
Standard Name
HEH2
Aliases
PreTt08260 | 262.m00035 | 3804.m00139
Description
cyclic nucleotide-binding domain containing protein; protein of unknown function; localizes to basal bodies; expressed during vegetative growth; homolog of human disease gene KIAA1279, implicated in nervous system development and Goldberg-Shprintzen syndrome; no homolog in S. cerevisiae
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
Cellular Component
No Data fetched for Domains
Tetrahymena Functional Genomics Database:
Signal Peptide Present?: No
TTHERM_01169510
Fullscreen View
No Data fetched for StockID
(v.2006 protein sequences)
Source Identifier Score Description
Tetrahymena borealis EI9_20340.1 9.997093137033517e-262 cyclic nucleotide-binding doma
Oxytricha Contig6878.0.g46 5.997739233660418e-28 Cyclic nucleotide-binding doma
Stentor Coeruleus SteCoe_9224 6.305116760146989e-16
SGD YIL033C 0.0000000020002373268528243 BCY1 Regulatory subunit of the
WormBase WBGene00001173 0.0000000039998859049333245 locus:egl-4 cGMP-dependent p
Paragraph No Gene Name Paragraph Text 6 HEH2 HEH2 is expressed during vegetative growth of T. thermophila and its protein product has been localized to basal bodies. Interestingly, its protein product was found to have high sequence similarity to the human disease gene KIAA1279. Human KIAA1279 was also found to have homologs in fruit fly, frog, rat, mouse, bee, chicken, and Japanese puffer fish, but none in Saccharomyces cerevisiae. Although the function of KIAA1279 is not yet known, evidence suggests that KIAA1279 is important in the development of the enteric and central nervous system (CNS). KIAA1279 was expressed in different parts of the adult CNS, and mutations in KIAA1279 were associated with Goldberg-Shprintzen syndrome (OMIM). 7 HEH2 HEH2 appears to be located on the right arm of micronuclear chromosome 2 based on mapping REP6, a locus upstream of HEH2.
No Data fetched for Associated Literature
>TTHERM_01169510(coding)ATG AGT GTA TAA TAG GAT AGA CTG AAT TAA ATT ATT GAA ATT TTA AAA ACT CCT TCA TCC CTT AGA GCC GAA GTA TAG ATA AGT TTC TTG TAG CAA GAG ACA AAT CAT ATA GGT CTA TTC AAA TAA TAC AAG GAA GAA GAT GGA GAT GAT GAG CTT TAG AGG CTT TGT TGT ATG TAT ATG AAG TAT GAA TAT CAA TCA AAA GAT TAA ACT CTA TTC AAC ATA GAT GAT TTT GGT ACC AAG TTC TAT ATC ATA TTA TCA GGA AAG GTA GGT GTT TAT ATT CGC ATG CCT AAA CAA AAA AGG TTA GAA TTA TTT TAG GAA TAA AAT AAC TAA AAT AAA GCA CAT GAG CCA GAT CCT TTA CAA ATG GTA AAG GAA TTA AGA ATG GGA GAT TCA TTT GGA GAG CTA GCC CTT CTT AAA AAT AGT AAA AGA TTA GCT ACT ATT ATA TGC AAG GAA GAT TGT CAT TTT GGT GTC ATT GAT AAA AAA ATT TTT AAC TTA GCA CTC AAA GAA AAG GAA GAA GAA AAA CTA AAT ATT TAA ATG AGA TTC TTA GCT AAT TCT CCT TTG TTT AGT AGA TTG CCA AAA AAC ACT ATT AAG CAT CTT CAT ATG AAT GCG TTT TAT GTA TAG TAC TAA AAA GGT CAA CCT GTT TAC TTA GAA GGA CAA AAC TCC AAC TCT TGC TTT GTA ATC AAA AGT GGA GAG TTT ACT ATA TAT AAA ACT ATT CAA CAT GTT ATG AAG ACT CAT GAA AAA AAA AAC TAA TAT TTG ACA GGT GGA GAG TAA AAA AAT TTA GAT ATT AAA ATA AGT GTT TTA GGT AAA GGT GAA CTT TTT GGT GAA ATT GAA TTG ATA TAA GGA GAT TCA CGC TGC ACT AGT GCT TTT TGT TCA AGC TTA GAT GGA GGA GAG TTA ATG ATT ATT AAC AGG ACT GAT TTA GAA AAT AAA GTT TTA TGT GAA GAG GAA TAT ATG CAA TAG TTT TAA AAT TAT ATT AAA ATG AAA AAG GAA TAG CTA AAA AAG AGA ATA GAA GGG ATT AAA AAT TAG CTA CAC AAA TAC CAA ACT TAT AGG TTT ATG ACA AGC GCG TTA AAA ATT CAT GAA GTA GAT GTT TGT GAG AAA ATA AAA AAT AAA GAG CTA AAT TAC TCA ATT GAT GTT TTA GAT GAT GTT ATT CAG AGT TAA ACT GAT AAA AAT GAT GAT GAT GAA GTA GGA ATT TTA TCA GCC TAA AAG TCT TCC AAA TTA AAG TAG CTA TAA CAA GTT TAG AAA TAT AAA CCG AAG TCT AAA TCT TCA ATT AAT ATT TTG AGC AAC ACT AAT TTA AAA TTT TAG AAT AAT TAG AGT TAA ACA AGT CTA CTA AAT TTG GCA TCA ATA AAT GAT TTA GCT AAT CAT GAA GAA AAT TCA TAA TTA AAA TCA TAA AAC TCA CAA TAA TAA ATC ACA TAA CCT TCT TCA CAA GAA AAG TTA AAT ATA AAC AGT TCT CAG TAA ATA AAT AAT TTT GCT CCT GTG GAA GAT AAG AAA ATC AAT GAA GTA ACT GCT CAT ATC ACT AAA AAC TCA AAG GAA TAG TTT ATG AAT AAA TGG TTT AAA TAT GGA GAA GGA GAA GAA GGT CCA TAA TAA AGT GAA AAT AAA TCT AAA AAA TAA AAA TTA TTG AGA GTA GAG CTG AAT TCT TAC ACT GAA TTA AAA AAT AGC ATC AGA AAA AAA ACA GCT ATT GCC TTA AGT AAG CAG TAT CGC CTT CCT TAT GAA AAA TTT ATG TAT GCT GGA AGC ATG TAT GAC ATA AGT TAA AGC GAA GAT TGG ATG AAA TAA TAA CAA ATG TAA CCT TAG TAA TAA CCA GAT ACA ATT AAC AGG AAG ACA ATA TCT TCT TTA TCA AAA TTA AGA GTT TAG ACA TAA GCA ACA CTA AAT CAT ATC TAA ACA TGC AGA CAT ATG AGC TAA ACT GAT AAT TTC TAA GTA GAA AAT TAG TCT TCT ATT CAT AAG ATT AAG AGT TTA GCA TGT TTA GAT GCC AAA TAA AAT CTG AAT AAT ATA AAA TAA TAA TAA AAA CCT GTA ATT AAA GAG GAT TTT TAA CAC CTA AAA AGT ATC TAG TAA TTT AGC CTA CCT GAT GAA TAA GCT AAA AAC AAC TTT TTT AAT TCT ATT TAA AGA ATT TAA AGC AGT GTC AGC TTA AAA TCT TAG GAT AGC AAA AAT TGG ATT AGC AAG TAA TAA AAA GAA AAT GAT AAT TTT AAA TCA GAG CTA TTG GAC AAG CTT TAA CAA TTT AAA TAA CAT TAA TAA CAT TAA TAA TCA TAA AAT GAT ATT CCA AAT TTA AAA AAA TAA AGT TCA AAA AGT CCA AAA AAA GAC ACT GAT TTA ATT GAA GAT GTA AAT TTA ATG AAG AGC ATA GAA GAT CAT TAT AAT AAT AGT CTA ACA GAA GAG GGT AGC AAA AAG TAC TAA AAG AAA CTA AAA AAC ATT TTA AAG CTT GAT ATT CAG CAT GAA TCT TCT GAT AAT TCC AGG ACA AGC ACA TCA AAT CTC AAT ACT CCA AAA TTA ATT TAA AGC AAA AAA GCT AGC TAA GCA TCT CTA TTT AAT ATG AGC TCT TCT ACA AAT TTA AAA TCC TAA CAA AAC TTA GAC AAT AAG TCC TAG TTT AGT AGT ATA CCT CTA AAG AAT GCT GAA ATT CTT TTT GAA AAA TAA GGT AAA AAA TTA TAA AAA AAG CAA CAT CTA AGA CTT CAT GAA AAT AAA GAC TCA CCT CTT AAG TTT CAA TTT TCA TAA TCC ACA AGA CAC TCA ATG GCA ACA AAT TAT TTT TAA CCA AAA AAT TTC GTT GAA GAT TAA AAC TAA CTC CCT TAT TGG GTA TAA CCA CTT AGC ACC CAG AAT AGT GAT TAA TAG CAA TAC TCT AAA AAT TAA ATA ATT GAT TTT AAT AAT TAA AAT AAT TAA TCT CTC TCT TAA ACA TTA TCT CCT TAA AAT TAG AAA TAA AAA TAA TAT AAA ATG CAA TTA TCT TCA TAC TTT AAA CCT AAA AAT ATA AAA AGT GAA TTT GGA GAA GAT TTA GAA AAA GAA ACA TCT TTA ATT GAT AAG CAA TTA TCC AAA GAA TAA AAT TAA TTA ACT CTA TCT CAG AAT AAA TAA AAA TCC TTC ATT TAC AAA AAC AAC TCC TCT GCT CAT GAG ATG AAT TAA ATT ATT TCT ATA AAA TCC GTA AAT AAT TTG TCT GAC TTA AAT AAT AGA GCA ATT TCG TCA GAG AGA TAA TTT AGA TAA AAA TAA TAA ACA AAT GGA AGC AGC AGC TAA AAT ATA TTT TAT AAA ACA TTT CAT TAA AAT AAA AAA ATA CTT AAA AAC ATA GCA CCC TAC AAT AAC AAA AAA CAA ACT TTA GAA CAA CCT GCA ATT TAT AAA TTT CAA TAA GAT TCT CCT TTA AAA GTT AAA AAA TAT TAA TAA CTA CTA TAA CCT TAA CAA TAG CAA TAC AAT TTA CTA AAT TAA ATT CTT TCT ACT CCA AAA ATT ACT AAT AAC TCT TGA >TTHERM_01169510(protein)M S V Q Q D R L N Q I I E I L K T P S S L R A E V Q I S F L Q Q E T N H I G L F K Q Y K E E D G D D E L Q R L C C M Y M K Y E Y Q S K D Q T L F N I D D F G T K F Y I I L S G K V G V Y I R M P K Q K R L E L F Q E Q N N Q N K A H E P D P L Q M V K E L R M G D S F G E L A L L K N S K R L A T I I C K E D C H F G V I D K K I F N L A L K E K E E E K L N I Q M R F L A N S P L F S R L P K N T I K H L H M N A F Y V Q Y Q K G Q P V Y L E G Q N S N S C F V I K S G E F T I Y K T I Q H V M K T H E K K N Q Y L T G G E Q K N L D I K I S V L G K G E L F G E I E L I Q G D S R C T S A F C S S L D G G E L M I I N R T D L E N K V L C E E E Y M Q Q F Q N Y I K M K K E Q L K K R I E G I K N Q L H K Y Q T Y R F M T S A L K I H E V D V C E K I K N K E L N Y S I D V L D D V I Q S Q T D K N D D D E V G I L S A Q K S S K L K Q L Q Q V Q K Y K P K S K S S I N I L S N T N L K F Q N N Q S Q T S L L N L A S I N D L A N H E E N S Q L K S Q N S Q Q Q I T Q P S S Q E K L N I N S S Q Q I N N F A P V E D K K I N E V T A H I T K N S K E Q F M N K W F K Y G E G E E G P Q Q S E N K S K K Q K L L R V E L N S Y T E L K N S I R K K T A I A L S K Q Y R L P Y E K F M Y A G S M Y D I S Q S E D W M K Q Q Q M Q P Q Q Q P D T I N R K T I S S L S K L R V Q T Q A T L N H I Q T C R H M S Q T D N F Q V E N Q S S I H K I K S L A C L D A K Q N L N N I K Q Q Q K P V I K E D F Q H L K S I Q Q F S L P D E Q A K N N F F N S I Q R I Q S S V S L K S Q D S K N W I S K Q Q K E N D N F K S E L L D K L Q Q F K Q H Q Q H Q Q S Q N D I P N L K K Q S S K S P K K D T D L I E D V N L M K S I E D H Y N N S L T E E G S K K Y Q K K L K N I L K L D I Q H E S S D N S R T S T S N L N T P K L I Q S K K A S Q A S L F N M S S S T N L K S Q Q N L D N K S Q F S S I P L K N A E I L F E K Q G K K L Q K K Q H L R L H E N K D S P L K F Q F S Q S T R H S M A T N Y F Q P K N F V E D Q N Q L P Y W V Q P L S T Q N S D Q Q Q Y S K N Q I I D F N N Q N N Q S L S Q T L S P Q N Q K Q K Q Y K M Q L S S Y F K P K N I K S E F G E D L E K E T S L I D K Q L S K E Q N Q L T L S Q N K Q K S F I Y K N N S S A H E M N Q I I S I K S V N N L S D L N N R A I S S E R Q F R Q K Q Q T N G S S S Q N I F Y K T F H Q N K K I L K N I A P Y N N K K Q T L E Q P A I Y K F Q Q D S P L K V K K Y Q Q L L Q P Q Q Q Q Y N L L N Q I L S T P K I T N N S >TTHERM_01169510(gene)GTT TTT ATT AAT CAC ATT TAT TTG ATA AAA ATT TAA TAT AAC AAA TTT GCT CAA AAA CTA ACA GTA AAT TAA ACT CTT TGG TAA AAG GAT TCA AAG CAT TGT GGT GAG CTA AAA TTT ATA TAA GAA CAA CTT TCG AAT TTT TAT AAA ATG AGT GTA TAA TAG GAT AGA CTG AAT GTA ATT TCA TAT GTT TTT TCT TTG AAA ATA AAT GTT TTT CAT CAA ATA TGA TGA AAG TTA TTT TGT ATC ATT TTG CTT ATT TTA GTT ATG ATT ATA ATT AGT AAA TTA TTG AAA TTT TAA AAA CTC CTT CAT CCC TTA GAG CCG AAG TAT AGA TAA GTT TCT TGT AGC AAG AGA CAA ATC ATA TAG GTC TAT TCA AAT AAT ACA AGG AAG AAG ATG GAG ATG ATG AGC TTT AGA GGC TTT GTT GTA TGT ATA TGA AGT ATG AAT ATC AAT CAA AAG ATT AAA CTC TAT TCA ACA TAG GTA ATG ATT GCT TAA ATT ATG TTT AAA CAT TAA ATG TTT AAG CTT TTA TTA TTT TTA GTT GCT CAT AAA TTT TAA ATA TAA TAT TTT TAT AGA TGA TTT TGG TAC CAA GTT CTA TAT CAT ATT ATC AGG AAA GGT AGG TGT TTA TAT TCG CAT GCC TAA ACA AAA AAG GTT AGA ATT ATT TTA GGA ATA AAA TAA CTA AAA TAA AGC ACA TGA GCC AGA TCC TTT ACA AAT GGT AAA GGA ATT AAG AAT GGG AGA TTC ATT TGG AGA GCT AGC CCT TCT TAA AAA TAG TAA AAG ATT AGC TAC TAT TAT ATG CAA GGA AGA TTG TCA TTT TGG TGT CAT TGA TAA AAA AAT TTT TAA CTT AGC ACT CAA AGA AAA GGA AGA AGA AAA ACT AAA TAT TTA AAT GAG ATT CTT AGC TAA TTC TCC TTT GTT TAG TAG ATT GCC AAA AAA CAC TAT TAA GCA TCT TCA TAT GAA TGC GTT TTA TGT ATA GTA CTA AAA AGG TCA ACC TGT TTA CTT AGA AGG ACA AAA CTC CAA CTC TTG CTT TGT AAT CAA AAG TGG AGA GTT TAC TGT AAT AAT TTT ATT ACT TCA GTA TTT AAT CTT AAA AAT AAA TTA TTT TTA AGA TTT TTA TAA AAA AAA AGT AGA AAT AAT ATC AAA TAT TTA TAT AAA ACT TAT TAA AAA TAC AGA TAT ATA AAA CTA TTC AAC ATG TTA TGA AGA CTC ATG AAA AAA AAA ACT AAT ATT TGA CAG GTG GAG AGT AAA AAA ATT TAG ATA TTA AAG TAA TTC AAT TAT TTT CTA TTA AAT ATA TTT ATA ATT TAT TTT TTT TAA ATG AAA ATA AAA GAT AAG TGT TTT AGG TAA AGG TGA ACT TTT TGG TGA AAT TGA ATT GAT ATA AGG AGA TTC ACG CTG CAC TAG TGC TTT TTG TTC AAG CTT AGA TGG AGG AGA GTT AAT GAT TAT TAA CAG GAC TGA TTT AGA AAA TAA AGT TTT ATG TGA AGA GGA ATA TAT GCA ATA GTT TTA AAA TTA TAT TAA AAT GAA AAA GGA ATA GCT AAA AAA GAG AAT AGA AGG GAT TAA AAA TTA GCT ACA CAA ATA CCA AAC TTA TAG GTT TAT GAC AAG CGC GTT AAA AAT TCA TGA AGT AGA TGT TTG TGA GAA AAT AAA AAA TAA AGA GCT AAA TTA CTC AAT TGA TGT TTT AGA TGA TGT TAT TCA GAG TTA AAC TGA TAA AAA TGA TGA TGA TGA AGT AGG AAT TTT ATC AGC CTA AAA GTC TTC CAA ATT AAA GTA GCT ATA ACA AGT TTA GAA ATA TAA ACC GAA GTC TAA ATC TTC AAT TAA TAT TTT GAG CAA CAC TAA TTT AAA ATT TTA GAA TAA TTA GAG TTA AAC AAG TCT ACT AAA TTT GGC ATC AAT AAA TGA TTT AGC TAA TCA TGA AGA AAA TTC ATA ATT AAA ATC ATA AAA CTC ACA ATA ATA AAT CAC ATA ACC TTC TTC ACA AGA AAA GTT AAA TAT AAA CAG TTC TCA GTA AAT AAA TAA TTT TGC TCC TGT GGA AGA TAA GAA AAT CAA TGA AGT AAC TGC TCA TAT CAC TAA AAA CTC AAA GGA ATA GTT TAT GAA TAA ATG GTT TAA ATA TGG AGA AGG AGA AGA AGG TCC ATA ATA AAG TGA AAA TAA ATC TAA AAA ATA AAA ATT ATT GAG AGT AGA GCT GAA TTC TTA CAC TGA ATT AAA AAA TAG CAT CAG AAA AAA AAC AGC TAT TGC CTT AAG TAA GCA GTA TCG CCT TCC TTA TGA AAA ATT TAT GTA TGC TGG AAG CAT GTA TGA CAT AAG TTA AAG CGA AGA TTG GAT GAA ATA ATA ACA AAT GTA ACC TTA GTA ATA ACC AGA TAC AAT TAA CAG GAA GAC AAT ATC TTC TTT ATC AAA ATT AAG AGT TTA GAC ATA AGC AAC ACT AAA TCA TAT CTA AAC ATG CAG ACA TAT GAG CTA AAC TGA TAA TTT CTA AGT AGA AAA TTA GTC TTC TAT TCA TAA GAT TAA GAG TTT AGC ATG TTT AGA TGC CAA ATA AAA TCT GAA TAA TAT AAA ATA ATA ATA AAA ACC TGT AAT TAA AGA GGA TTT TTA ACA CCT AAA AAG TAT CTA GTA ATT TAG CCT ACC TGA TGA ATA AGC TAA AAA CAA CTT TTT TAA TTC TAT TTA AAG AAT TTA AAG CAG TGT CAG CTT AAA ATC TTA GGA TAG CAA AAA TTG GAT TAG CAA GTA ATA AAA AGA AAA TGA TAA TTT TAA ATC AGA GCT ATT GGA CAA GCT TTA ACA ATT TAA ATA ACA TTA ATA ACA TTA ATA ATC ATA AAA TGA TAT TCC AAA TTT AAA AAA ATA AAG TTC AAA AAG TCC AAA AAA AGA CAC TGA TTT AAT TGA AGA TGT AAA TTT AAT GAA GAG CAT AGA AGA TCA TTA TAA TAA TAG TCT AAC AGA AGA GGG TAG CAA AAA GTA CTA AAA GAA ACT AAA AAA CAT TTT AAA GCT TGA TAT TCA GCA TGA ATC TTC TGA TAA TTC CAG GAC AAG CAC ATC AAA TCT CAA TAC TCC AAA ATT AAT TTA AAG CAA AAA AGC TAG CTA AGC ATC TCT ATT TAA TAT GAG CTC TTC TAC AAA TTT AAA ATC CTA ACA AAA CTT AGA CAA TAA GTC CTA GTT TAG TAG TAT ACC TCT AAA GAA TGC TGA AAT TCT TTT TGA AAA ATA AGG TAA AAA ATT ATA AAA AAA GCA ACA TCT AAG ACT TCA TGA AAA TAA AGA CTC ACC TCT TAA GTT TCA ATT TTC ATA ATC CAC AAG ACA CTC AAT GGC AAC AAA TTA TTT TTA ACC AAA AAA TTT CGT TGA AGA TTA AAA CTA ACT CCC TTA TTG GGT ATA ACC ACT TAG CAC CCA GAA TAG TGA TTA ATA GCA ATA CTC TAA AAA TTA AAT AAT TGA TTT TAA TAA TTA AAA TAA TTA ATC TCT CTC TTA AAC ATT ATC TCC TTA AAA TTA GAA ATA AAA ATA ATA TAA AAT GCA ATT ATC TTC ATA CTT TAA ACC TAA AAA TAT AAA AAG TGA ATT TGG AGA AGA TTT AGA AAA AGA AAC ATC TTT AAT TGA TAA GCA ATT ATC CAA AGA ATA AAA TTA ATT AAC TCT ATC TCA GAA TAA ATA AAA ATC CTT CAT TTA CAA AAA CAA CTC CTC TGC TCA TGA GAT GAA TTA AAT TAT TTC TAT AAA ATC CGT AAA TAA TTT GTC TGA CTT AAA TAA TAG AGC AAT TTC GTC AGA GAG ATA ATT TAG ATA AAA ATA ATA AAC AAA TGG AAG CAG CAG CTA AAA TAT ATT TTA TAA AAC ATT TCA TTA AAA TAA AAA AAT ACT TAA AAA CAT AGC ACC CTA CAA TAA CAA AAA ACA AAC TTT AGA ACA ACC TGC AAT TTA TAA ATT TCA ATA AGA TTC TCC TTT AAA AGT TAA AAA ATA TTA ATA ACT ACT ATA ACC TTA ACA ATA GCA ATA CAA TTT ACT AAA TTA AAT TCT TTC TAC TCC AAA AAT TAC TAA TAA CTC TTG A
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