Gene Model Identifier
TTHERM_01169510
Standard Name
HEH2
Aliases
PreTt08260 | 262.m00035 | 3804.m00139
Description
HEH2 cyclic nucleotide-binding domain protein; cyclic nucleotide-binding domain containing protein; protein of unknown function; localizes to basal bodies; expressed during vegetative growth; homolog of human disease gene KIAA1279- implicated in nervous system development and Goldberg-Shprintzen syndrome; no homolog in S. cerevisiae
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
Cellular Component
No Data fetched for Domains
Tetrahymena Functional Genomics Database:
Signal Peptide Present?: No
TTHERM_01169510
Fullscreen View
No Data fetched for StockID
(v.2006 protein sequences)
Source Identifier Score Description
Tetrahymena borealis EI9_20340.1 9.997093137033517e-262 cyclic nucleotide-binding doma
Oxytricha Contig6878.0.g46 5.997739233660418e-28 Cyclic nucleotide-binding doma
Stentor Coeruleus SteCoe_9224 6.305116760146989e-16
SGD YIL033C 0.0000000020002373268528243 BCY1 Regulatory subunit of the
WormBase WBGene00001173 0.0000000039998859049333245 locus:egl-4 cGMP-dependent p
Paragraph No Gene Name Paragraph Text 6 HEH2 HEH2 is expressed during vegetative growth of T. thermophila and its protein product has been localized to basal bodies. Interestingly, its protein product was found to have high sequence similarity to the human disease gene KIAA1279. Human KIAA1279 was also found to have homologs in fruit fly, frog, rat, mouse, bee, chicken, and Japanese puffer fish, but none in Saccharomyces cerevisiae. Although the function of KIAA1279 is not yet known, evidence suggests that KIAA1279 is important in the development of the enteric and central nervous system (CNS). KIAA1279 was expressed in different parts of the adult CNS, and mutations in KIAA1279 were associated with Goldberg-Shprintzen syndrome (OMIM). 7 HEH2 HEH2 appears to be located on the right arm of micronuclear chromosome 2 based on mapping REP6, a locus upstream of HEH2.
No Data fetched for Associated Literature
>TTHERM_01169510(coding)ATG AGT GTA TAA TAG GAT AGA CTG AAT TAA ATT ATT GAA ATT TTA AAA ACT CCT TCA TCC CTT AGA GCC GAA GTA TAG ATA AGT TTC TTG TAG CAA GAG ACA AAT CAT ATA GGT CTA TTC AAA TAA TAC AAG GAA GAA GAT GGA GAT GAT GAG CTT TAG AGG CTT TGT TGT ATG TAT ATG AAG TAT GAA TAT CAA TCA AAA GAT TAA ACT CTA TTC AAC ATA GAT GAT TTT GGT ACC AAG TTC TAT ATC ATA TTA TCA GGA AAG GTA GGT GTT TAT ATT CGC ATG CCT AAA CAA AAA AGG TTA GAA TTA TTT TAG GAA TAA AAT AAC TAA AAT AAA GCA CAT GAG CCA GAT CCT TTA CAA ATG GTA AAG GAA TTA AGA ATG GGA GAT TCA TTT GGA GAG CTA GCC CTT CTT AAA AAT AGT AAA AGA TTA GCT ACT ATT ATA TGC AAG GAA GAT TGT CAT TTT GGT GTC ATT GAT AAA AAA ATT TTT AAC TTA GCA CTC AAA GAA AAG GAA GAA GAA AAA CTA AAT ATT TAA ATG AGA TTC TTA GCT AAT TCT CCT TTG TTT AGT AGA TTG CCA AAA AAC ACT ATT AAG CAT CTT CAT ATG AAT GCG TTT TAT GTA TAG TAC TAA AAA GGT CAA CCT GTT TAC TTA GAA GGA CAA AAC TCC AAC TCT TGC TTT GTA ATC AAA AGT GGA GAG TTT ACT ATA TAT AAA ACT ATT CAA CAT GTT ATG AAG ACT CAT GAA AAA AAA AAC TAA TAT TTG ACA GGT GGA GAG TAA AAA AAT TTA GAT ATT AAA ATA AGT GTT TTA GGT AAA GGT GAA CTT TTT GGT GAA ATT GAA TTG ATA TAA GGA GAT TCA CGC TGC ACT AGT GCT TTT TGT TCA AGC TTA GAT GGA GGA GAG TTA ATG ATT ATT AAC AGG ACT GAT TTA GAA AAT AAA GTT TTA TGT GAA GAG GAA TAT ATG CAA TAG TTT TAA AAT TAT ATT AAA ATG AAA AAG GAA TAG CTA AAA AAG AGA ATA GAA GGG ATT AAA AAT TAG CTA CAC AAA TAC CAA ACT TAT AGG TTT ATG ACA AGC GCG TTA AAA ATT CAT GAA GTA GAT GTT TGT GAG AAA ATA AAA AAT AAA GAG CTA AAT TAC TCA ATT GAT GTT TTA GAT GAT GTT ATT CAG AGT TAA ACT GAT AAA AAT GAT GAT GAT GAA GTA GGA ATT TTA TCA GCC TAA AAG TCT TCC AAA TTA AAG TAG CTA TAA CAA GTT TAG AAA TAT AAA CCG AAG TCT AAA TCT TCA ATT AAT ATT TTG AGC AAC ACT AAT TTA AAA TTT TAG AAT AAT TAG AGT TAA ACA AGT CTA CTA AAT TTG GCA TCA ATA AAT GAT TTA GCT AAT CAT GAA GAA AAT TCA TAA TTA AAA TCA TAA AAC TCA CAA TAA TAA ATC ACA TAA CCT TCT TCA CAA GAA AAG TTA AAT ATA AAC AGT TCT CAG TAA ATA AAT AAT TTT GCT CCT GTG GAA GAT AAG AAA ATC AAT GAA GTA ACT GCT CAT ATC ACT AAA AAC TCA AAG GAA TAG TTT ATG AAT AAA TGG TTT AAA TAT GGA GAA GGA GAA GAA GGT CCA TAA TAA AGT GAA AAT AAA TCT AAA AAA TAA AAA TTA TTG AGA GTA GAG CTG AAT TCT TAC ACT GAA TTA AAA AAT AGC ATC AGA AAA AAA ACA GCT ATT GCC TTA AGT AAG CAG TAT CGC CTT CCT TAT GAA AAA TTT ATG TAT GCT GGA AGC ATG TAT GAC ATA AGT TAA AGC GAA GAT TGG ATG AAA TAA TAA CAA ATG TAA CCT TAG TAA TAA CCA GAT ACA ATT AAC AGG AAG ACA ATA TCT TCT TTA TCA AAA TTA AGA GTT TAG ACA TAA GCA ACA CTA AAT CAT ATC TAA ACA TGC AGA CAT ATG AGC TAA ACT GAT AAT TTC TAA GTA GAA AAT TAG TCT TCT ATT CAT AAG ATT AAG AGT TTA GCA TGT TTA GAT GCC AAA TAA AAT CTG AAT AAT ATA AAA TAA TAA TAA AAA CCT GTA ATT AAA GAG GAT TTT TAA CAC CTA AAA AGT ATC TAG TAA TTT AGC CTA CCT GAT GAA TAA GCT AAA AAC AAC TTT TTT AAT TCT ATT TAA AGA ATT TAA AGC AGT GTC AGC TTA AAA TCT TAG GAT AGC AAA AAT TGG ATT AGC AAG TAA TAA AAA GAA AAT GAT AAT TTT AAA TCA GAG CTA TTG GAC AAG CTT TAA CAA TTT AAA TAA CAT TAA TAA CAT TAA TAA TCA TAA AAT GAT ATT CCA AAT TTA AAA AAA TAA AGT TCA AAA AGT CCA AAA AAA GAC ACT GAT TTA ATT GAA GAT GTA AAT TTA ATG AAG AGC ATA GAA GAT CAT TAT AAT AAT AGT CTA ACA GAA GAG GGT AGC AAA AAG TAC TAA AAG AAA CTA AAA AAC ATT TTA AAG CTT GAT ATT CAG CAT GAA TCT TCT GAT AAT TCC AGG ACA AGC ACA TCA AAT CTC AAT ACT CCA AAA TTA ATT TAA AGC AAA AAA GCT AGC TAA GCA TCT CTA TTT AAT ATG AGC TCT TCT ACA AAT TTA AAA TCC TAA CAA AAC TTA GAC AAT AAG TCC TAG TTT AGT AGT ATA CCT CTA AAG AAT GCT GAA ATT CTT TTT GAA AAA TAA GGT AAA AAA TTA TAA AAA AAG CAA CAT CTA AGA CTT CAT GAA AAT AAA GAC TCA CCT CTT AAG TTT CAA TTT TCA TAA TCC ACA AGA CAC TCA ATG GCA ACA AAT TAT TTT TAA CCA AAA AAT TTC GTT GAA GAT TAA AAC TAA CTC CCT TAT TGG GTA TAA CCA CTT AGC ACC CAG AAT AGT GAT TAA TAG CAA TAC TCT AAA AAT TAA ATA ATT GAT TTT AAT AAT TAA AAT AAT TAA TCT CTC TCT TAA ACA TTA TCT CCT TAA AAT TAG AAA TAA AAA TAA TAT AAA ATG CAA TTA TCT TCA TAC TTT AAA CCT AAA AAT ATA AAA AGT GAA TTT GGA GAA GAT TTA GAA AAA GAA ACA TCT TTA ATT GAT AAG CAA TTA TCC AAA GAA TAA AAT TAA TTA ACT CTA TCT CAG AAT AAA TAA AAA TCC TTC ATT TAC AAA AAC AAC TCC TCT GCT CAT GAG ATG AAT TAA ATT ATT TCT ATA AAA TCC GTA AAT AAT TTG TCT GAC TTA AAT AAT AGA GCA ATT TCG TCA GAG AGA TAA TTT AGA TAA AAA TAA TAA ACA AAT GGA AGC AGC AGC TAA AAT ATA TTT TAT AAA ACA TTT CAT TAA AAT AAA AAA ATA CTT AAA AAC ATA GCA CCC TAC AAT AAC AAA AAA CAA ACT TTA GAA CAA CCT GCA ATT TAT AAA TTT CAA TAA GAT TCT CCT TTA AAA GTT AAA AAA TAT TAA TAA CTA CTA TAA CCT TAA CAA TAG CAA TAC AAT TTA CTA AAT TAA ATT CTT TCT ACT CCA AAA ATT ACT AAT AAC TCT TGA >TTHERM_01169510(protein)M S V Q Q D R L N Q I I E I L K T P S S L R A E V Q I S F L Q Q E T N H I G L F K Q Y K E E D G D D E L Q R L C C M Y M K Y E Y Q S K D Q T L F N I D D F G T K F Y I I L S G K V G V Y I R M P K Q K R L E L F Q E Q N N Q N K A H E P D P L Q M V K E L R M G D S F G E L A L L K N S K R L A T I I C K E D C H F G V I D K K I F N L A L K E K E E E K L N I Q M R F L A N S P L F S R L P K N T I K H L H M N A F Y V Q Y Q K G Q P V Y L E G Q N S N S C F V I K S G E F T I Y K T I Q H V M K T H E K K N Q Y L T G G E Q K N L D I K I S V L G K G E L F G E I E L I Q G D S R C T S A F C S S L D G G E L M I I N R T D L E N K V L C E E E Y M Q Q F Q N Y I K M K K E Q L K K R I E G I K N Q L H K Y Q T Y R F M T S A L K I H E V D V C E K I K N K E L N Y S I D V L D D V I Q S Q T D K N D D D E V G I L S A Q K S S K L K Q L Q Q V Q K Y K P K S K S S I N I L S N T N L K F Q N N Q S Q T S L L N L A S I N D L A N H E E N S Q L K S Q N S Q Q Q I T Q P S S Q E K L N I N S S Q Q I N N F A P V E D K K I N E V T A H I T K N S K E Q F M N K W F K Y G E G E E G P Q Q S E N K S K K Q K L L R V E L N S Y T E L K N S I R K K T A I A L S K Q Y R L P Y E K F M Y A G S M Y D I S Q S E D W M K Q Q Q M Q P Q Q Q P D T I N R K T I S S L S K L R V Q T Q A T L N H I Q T C R H M S Q T D N F Q V E N Q S S I H K I K S L A C L D A K Q N L N N I K Q Q Q K P V I K E D F Q H L K S I Q Q F S L P D E Q A K N N F F N S I Q R I Q S S V S L K S Q D S K N W I S K Q Q K E N D N F K S E L L D K L Q Q F K Q H Q Q H Q Q S Q N D I P N L K K Q S S K S P K K D T D L I E D V N L M K S I E D H Y N N S L T E E G S K K Y Q K K L K N I L K L D I Q H E S S D N S R T S T S N L N T P K L I Q S K K A S Q A S L F N M S S S T N L K S Q Q N L D N K S Q F S S I P L K N A E I L F E K Q G K K L Q K K Q H L R L H E N K D S P L K F Q F S Q S T R H S M A T N Y F Q P K N F V E D Q N Q L P Y W V Q P L S T Q N S D Q Q Q Y S K N Q I I D F N N Q N N Q S L S Q T L S P Q N Q K Q K Q Y K M Q L S S Y F K P K N I K S E F G E D L E K E T S L I D K Q L S K E Q N Q L T L S Q N K Q K S F I Y K N N S S A H E M N Q I I S I K S V N N L S D L N N R A I S S E R Q F R Q K Q Q T N G S S S Q N I F Y K T F H Q N K K I L K N I A P Y N N K K Q T L E Q P A I Y K F Q Q D S P L K V K K Y Q Q L L Q P Q Q Q Q Y N L L N Q I L S T P K I T N N S >TTHERM_01169510(gene)ATG TAT ACA TAT CTT TCT TTT ATA TTT ATA GCT AAA AAC TCA ATA AAT ACA GTA AAA AAA TCT AAC ACA ATT CAA ATT AAA TAA ACT TTT TTA AAA CTT TTA GAT AAG AAA ATT ATA AAT TTA AGA GCT ATG ATG AAA TAA TAC TTT CAC CAT TAA AAA AAA ATA TGC GTT AAA AAA AAT TTG TAT TAA AAA ATA AGT AAA AAT ATG TTC AAA ACA TAT GTT TTT AGA GTA TAA TAT TTA TTA AAA ATA ACG AGT GTG AAT AAT TTA AAC TTT TTG AAT ATT TTT TTA TCA ACA CTA ATA AGA TTT TTT AGT AGA TTT TGC TAT AAA ACT AGT AAT ATT TTG TAT TTT TGA TCA ATT AGC TAC AAA AAT CTT TAG GTG CAT GGA TGC TAT TAA GGA TTT TTT GAT TAT GGT ATT GTT GTA ATT AAT TAC TTT ACT TTT AAA TCA ATT CAA ATA GTA ACT AAA TTT GTT TGT AAA AAG TCA TAT TTT CAT CAC AAA ATT CAG TGA GAT AAT ATT CAG AAA TCA ATA TCA ATT AAT TAG TAA TCA AGC AAA ACC ATA AAA TAT TAC TAA AAA TAT TAA GAT AGG AGT TTT TAT TAA TCA CAT TTA TTT GAT AAA AAT TTA ATA TAA CAA ATT TGC TCA AAA ACT AAC AGT AAA TTA AAC TCT TTG GTA AAA GGA TTC AAA GCA TTG TGG TGA GCT AAA ATT TAT ATA AGA ACA ACT TTC GAA TTT TTA TAA AAT GAG TGT ATA ATA GGA TAG ACT GAA TGT AAT TTC ATA TGT TTT TTC TTT GAA AAT AAA TGT TTT TCA TCA AAT ATG ATG AAA GTT ATT TTG TAT CAT TTT GCT TAT TTT AGT TAT GAT TAT AAT TAG TAA ATT ATT GAA ATT TTA AAA ACT CCT TCA TCC CTT AGA GCC GAA GTA TAG ATA AGT TTC TTG TAG CAA GAG ACA AAT CAT ATA GGT CTA TTC AAA TAA TAC AAG GAA GAA GAT GGA GAT GAT GAG CTT TAG AGG CTT TGT TGT ATG TAT ATG AAG TAT GAA TAT CAA TCA AAA GAT TAA ACT CTA TTC AAC ATA GGT AAT GAT TGC TTA AAT TAT GTT TAA ACA TTA AAT GTT TAA GCT TTT ATT ATT TTT AGT TGC TCA TAA ATT TTA AAT ATA ATA TTT TTA TAG ATG ATT TTG GTA CCA AGT TCT ATA TCA TAT TAT CAG GAA AGG TAG GTG TTT ATA TTC GCA TGC CTA AAC AAA AAA GGT TAG AAT TAT TTT AGG AAT AAA ATA ACT AAA ATA AAG CAC ATG AGC CAG ATC CTT TAC AAA TGG TAA AGG AAT TAA GAA TGG GAG ATT CAT TTG GAG AGC TAG CCC TTC TTA AAA ATA GTA AAA GAT TAG CTA CTA TTA TAT GCA AGG AAG ATT GTC ATT TTG GTG TCA TTG ATA AAA AAA TTT TTA ACT TAG CAC TCA AAG AAA AGG AAG AAG AAA AAC TAA ATA TTT AAA TGA GAT TCT TAG CTA ATT CTC CTT TGT TTA GTA GAT TGC CAA AAA ACA CTA TTA AGC ATC TTC ATA TGA ATG CGT TTT ATG TAT AGT ACT AAA AAG GTC AAC CTG TTT ACT TAG AAG GAC AAA ACT CCA ACT CTT GCT TTG TAA TCA AAA GTG GAG AGT TTA CTG TAA TAA TTT TAT TAC TTC AGT ATT TAA TCT TAA AAA TAA ATT ATT TTT AAG ATT TTT ATA AAA AAA AAG TAG AAA TAA TAT CAA ATA TTT ATA TAA AAC TTA TTA AAA ATA CAG ATA TAT AAA ACT ATT CAA CAT GTT ATG AAG ACT CAT GAA AAA AAA AAC TAA TAT TTG ACA GGT GGA GAG TAA AAA AAT TTA GAT ATT AAA GTA ATT CAA TTA TTT TCT ATT AAA TAT ATT TAT AAT TTA TTT TTT TTA AAT GAA AAT AAA AGA TAA GTG TTT TAG GTA AAG GTG AAC TTT TTG GTG AAA TTG AAT TGA TAT AAG GAG ATT CAC GCT GCA CTA GTG CTT TTT GTT CAA GCT TAG ATG GAG GAG AGT TAA TGA TTA TTA ACA GGA CTG ATT TAG AAA ATA AAG TTT TAT GTG AAG AGG AAT ATA TGC AAT AGT TTT AAA ATT ATA TTA AAA TGA AAA AGG AAT AGC TAA AAA AGA GAA TAG AAG GGA TTA AAA ATT AGC TAC ACA AAT ACC AAA CTT ATA GGT TTA TGA CAA GCG CGT TAA AAA TTC ATG AAG TAG ATG TTT GTG AGA AAA TAA AAA ATA AAG AGC TAA ATT ACT CAA TTG ATG TTT TAG ATG ATG TTA TTC AGA GTT AAA CTG ATA AAA ATG ATG ATG ATG AAG TAG GAA TTT TAT CAG CCT AAA AGT CTT CCA AAT TAA AGT AGC TAT AAC AAG TTT AGA AAT ATA AAC CGA AGT CTA AAT CTT CAA TTA ATA TTT TGA GCA ACA CTA ATT TAA AAT TTT AGA ATA ATT AGA GTT AAA CAA GTC TAC TAA ATT TGG CAT CAA TAA ATG ATT TAG CTA ATC ATG AAG AAA ATT CAT AAT TAA AAT CAT AAA ACT CAC AAT AAT AAA TCA CAT AAC CTT CTT CAC AAG AAA AGT TAA ATA TAA ACA GTT CTC AGT AAA TAA ATA ATT TTG CTC CTG TGG AAG ATA AGA AAA TCA ATG AAG TAA CTG CTC ATA TCA CTA AAA ACT CAA AGG AAT AGT TTA TGA ATA AAT GGT TTA AAT ATG GAG AAG GAG AAG AAG GTC CAT AAT AAA GTG AAA ATA AAT CTA AAA AAT AAA AAT TAT TGA GAG TAG AGC TGA ATT CTT ACA CTG AAT TAA AAA ATA GCA TCA GAA AAA AAA CAG CTA TTG CCT TAA GTA AGC AGT ATC GCC TTC CTT ATG AAA AAT TTA TGT ATG CTG GAA GCA TGT ATG ACA TAA GTT AAA GCG AAG ATT GGA TGA AAT AAT AAC AAA TGT AAC CTT AGT AAT AAC CAG ATA CAA TTA ACA GGA AGA CAA TAT CTT CTT TAT CAA AAT TAA GAG TTT AGA CAT AAG CAA CAC TAA ATC ATA TCT AAA CAT GCA GAC ATA TGA GCT AAA CTG ATA ATT TCT AAG TAG AAA ATT AGT CTT CTA TTC ATA AGA TTA AGA GTT TAG CAT GTT TAG ATG CCA AAT AAA ATC TGA ATA ATA TAA AAT AAT AAT AAA AAC CTG TAA TTA AAG AGG ATT TTT AAC ACC TAA AAA GTA TCT AGT AAT TTA GCC TAC CTG ATG AAT AAG CTA AAA ACA ACT TTT TTA ATT CTA TTT AAA GAA TTT AAA GCA GTG TCA GCT TAA AAT CTT AGG ATA GCA AAA ATT GGA TTA GCA AGT AAT AAA AAG AAA ATG ATA ATT TTA AAT CAG AGC TAT TGG ACA AGC TTT AAC AAT TTA AAT AAC ATT AAT AAC ATT AAT AAT CAT AAA ATG ATA TTC CAA ATT TAA AAA AAT AAA GTT CAA AAA GTC CAA AAA AAG ACA CTG ATT TAA TTG AAG ATG TAA ATT TAA TGA AGA GCA TAG AAG ATC ATT ATA ATA ATA GTC TAA CAG AAG AGG GTA GCA AAA AGT ACT AAA AGA AAC TAA AAA ACA TTT TAA AGC TTG ATA TTC AGC ATG AAT CTT CTG ATA ATT CCA GGA CAA GCA CAT CAA ATC TCA ATA CTC CAA AAT TAA TTT AAA GCA AAA AAG CTA GCT AAG CAT CTC TAT TTA ATA TGA GCT CTT CTA CAA ATT TAA AAT CCT AAC AAA ACT TAG ACA ATA AGT CCT AGT TTA GTA GTA TAC CTC TAA AGA ATG CTG AAA TTC TTT TTG AAA AAT AAG GTA AAA AAT TAT AAA AAA AGC AAC ATC TAA GAC TTC ATG AAA ATA AAG ACT CAC CTC TTA AGT TTC AAT TTT CAT AAT CCA CAA GAC ACT CAA TGG CAA CAA ATT ATT TTT AAC CAA AAA ATT TCG TTG AAG ATT AAA ACT AAC TCC CTT ATT GGG TAT AAC CAC TTA GCA CCC AGA ATA GTG ATT AAT AGC AAT ACT CTA AAA ATT AAA TAA TTG ATT TTA ATA ATT AAA ATA ATT AAT CTC TCT CTT AAA CAT TAT CTC CTT AAA ATT AGA AAT AAA AAT AAT ATA AAA TGC AAT TAT CTT CAT ACT TTA AAC CTA AAA ATA TAA AAA GTG AAT TTG GAG AAG ATT TAG AAA AAG AAA CAT CTT TAA TTG ATA AGC AAT TAT CCA AAG AAT AAA ATT AAT TAA CTC TAT CTC AGA ATA AAT AAA AAT CCT TCA TTT ACA AAA ACA ACT CCT CTG CTC ATG AGA TGA ATT AAA TTA TTT CTA TAA AAT CCG TAA ATA ATT TGT CTG ACT TAA ATA ATA GAG CAA TTT CGT CAG AGA GAT AAT TTA GAT AAA AAT AAT AAA CAA ATG GAA GCA GCA GCT AAA ATA TAT TTT ATA AAA CAT TTC ATT AAA ATA AAA AAA TAC TTA AAA ACA TAG CAC CCT ACA ATA ACA AAA AAC AAA CTT TAG AAC AAC CTG CAA TTT ATA AAT TTC AAT AAG ATT CTC CTT TAA AAG TTA AAA AAT ATT AAT AAC TAC TAT AAC CTT AAC AAT AGC AAT ACA ATT TAC TAA ATT AAA TTC TTT CTA CTC CAA AAA TTA CTA ATA ACT CTT GA
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