TGD | Gene Details

Identifiers and Description

Gene Model Identifier
TTHERM_00840160

Standard Name
FLP4 (FLiPpase)

Aliases
PreTt17831 | 146.m00132 | 3743.m00061

Description
phospholipid-translocating P-type ATPase, flippase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component
membrane (IEA) | GO:0016020
integral to membrane (IEA) | GO:0016021
Molecular Function
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (IEA) | GO:0015662
ATP binding (IEA) | GO:0005524
ATPase activity (IEA) | GO:0016887
Biological Process
cation transport (IEA) | GO:0006812

Domains

( PF05965 ) F/Y rich C-terminus
( TIGR00099 ) Cof-like hydrolase
( TIGR01732 ) conserved hypothetical protein
( PF01311 ) Bacterial export proteins, family 1
( PF00702 ) haloacid dehalogenase-like hydrolase
( PF05316 ) Mitochondrial ribosomal protein (VAR1)
( TIGR01484 ) HAD-superfamily hydrolase, subfamily IIB
( TIGR01517 ) calcium-translocating P-type ATPase, PMCA-type
( TIGR01116 ) calcium-translocating P-type ATPase, SERCA-type
( TIGR01652 ) phospholipid-translocating P-type ATPase, flippase
( TIGR01494 ) ATPase, P-type (transporting), HAD superfamily,

Gene Expression Profile

Tetrahymena Functional Genomics Database: TTHERM_00840160

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source Identifier Score Description

Oxytricha Contig10033.0.g106 9.99709313703352e-262 E1-E2 ATPase

Tetrahymena borealis EI9_19527.1 9.99709313703352e-262 phospholipid-translocating...

ParameciumDB GSPATP00016583001 9.99709313703352e-262 Paramecium tetraurelia GSPATP0
0016583001 protein

DictyBase DDB0190219 1.00034910302318e-151 JC1V2_0_01058 Q9Y2Q0 Potential
phospholipid-transporting ATP
ase IA (EC 3.6.3.1) (Chromaffi
n granule ATPase II) (ATPase c
lass I type 8A member 1).

FlyBase FBgn0033837 1.00017887210854e-149

TAIR AT3G27870 9.99593845621775e-149 haloacid dehalogenase-like hyd
rolase family protein

WormBase Y49E10.11a 1.00025342324882e-144 WBGene00013034 tat-1 P-type AT
Pase

WormBase Y49E10.11b 1.00025342324882e-144 WBGene00013034 tat-1

IPI(HUMAN) IPI:IPI00152868.4 9.99668353155528e-144 PROT:Q8TF62|TREMBL:Q6PG43|ENS
EMBL:ENSP00000284509|REFSEQ: N
P_079113|H- INV:HIT000001654;H
IT000008399;HIT000043620;HIT00
0056143 Tax_Id=9606 Probable p
hospholipid-transporting ATPas
e IM

IPI(HUMAN) IPI:IPI00465166.1 9.99668353155528e-144 1|TREMBL:Q6ZSP3;Q6ZU25|ENSEMB
L:ENSP00000281620|H- INV:HIT00
0019508;HIT000025544;HIT000026
371;HIT000045904;H IT000047136
;HIT000054620|VEGA:OTTHUMP0000
0018151 Tax_Id=9606 CDNA FLJ45
330 fis, clone BRHIP3007195, h
ighly similar to Potential pho
spholipid-transporting ATPase
IB

SGD YAL026C 9.99987554273627e-136 DRS2 SGDID:S000000024, Chr I f
rom 99698-95631, reverse compl
ement, Verified ORF, "Integral
membrane Ca(2+)-ATPase involv
ed in aminophospholipid transl
ocation; required to form a sp
ecific class of secretory vesi
cles that accumulate upon acti
n cytoskeleton disruption; mut
ation affects maturation of th
e 18S rRNA"

CryptoDB EAK89054 1.00001985756599e-106 Cryptosporidium parvum (Iowa)
protein EAK89054

ToxoDB 50.m03192 1.00043485889854e-105 Toxoplasma gondii ATPase 2, pu
tative

PlasmoDB PFL0950c 6.99704686404971e-88 Plasmodium falciparum PFL0950c

Source	Identifier	Score	Description
Oxytricha	Contig10033.0.g106	9.99709313703352e-262	E1-E2 ATPase
Tetrahymena borealis	EI9_19527.1	9.99709313703352e-262	phospholipid-translocating...
ParameciumDB	GSPATP00016583001	9.99709313703352e-262	Paramecium tetraurelia GSPATP0 0016583001 protein
DictyBase	DDB0190219	1.00034910302318e-151	JC1V2_0_01058 Q9Y2Q0 Potential phospholipid-transporting ATP ase IA (EC 3.6.3.1) (Chromaffi n granule ATPase II) (ATPase c lass I type 8A member 1).
FlyBase	FBgn0033837	1.00017887210854e-149
TAIR	AT3G27870	9.99593845621775e-149	haloacid dehalogenase-like hyd rolase family protein
WormBase	Y49E10.11a	1.00025342324882e-144	WBGene00013034 tat-1 P-type AT Pase
WormBase	Y49E10.11b	1.00025342324882e-144	WBGene00013034 tat-1
IPI(HUMAN)	IPI:IPI00152868.4	9.99668353155528e-144	PROT:Q8TF62\|TREMBL:Q6PG43\|ENS EMBL:ENSP00000284509\|REFSEQ: N P_079113\|H- INV:HIT000001654;H IT000008399;HIT000043620;HIT00 0056143 Tax_Id=9606 Probable p hospholipid-transporting ATPas e IM
IPI(HUMAN)	IPI:IPI00465166.1	9.99668353155528e-144	1\|TREMBL:Q6ZSP3;Q6ZU25\|ENSEMB L:ENSP00000281620\|H- INV:HIT00 0019508;HIT000025544;HIT000026 371;HIT000045904;H IT000047136 ;HIT000054620\|VEGA:OTTHUMP0000 0018151 Tax_Id=9606 CDNA FLJ45 330 fis, clone BRHIP3007195, h ighly similar to Potential pho spholipid-transporting ATPase IB
SGD	YAL026C	9.99987554273627e-136	DRS2 SGDID:S000000024, Chr I f rom 99698-95631, reverse compl ement, Verified ORF, "Integral membrane Ca(2+)-ATPase involv ed in aminophospholipid transl ocation; required to form a sp ecific class of secretory vesi cles that accumulate upon acti n cytoskeleton disruption; mut ation affects maturation of th e 18S rRNA"
CryptoDB	EAK89054	1.00001985756599e-106	Cryptosporidium parvum (Iowa) protein EAK89054
ToxoDB	50.m03192	1.00043485889854e-105	Toxoplasma gondii ATPase 2, pu tative
PlasmoDB	PFL0950c	6.99704686404971e-88	Plasmodium falciparum PFL0950c

General Information

Paragraph No Gene Name Paragraph Text
19 FLP11,
FLP18,
FLP17,
FLP8,
FLP16,
FLP15,
FLP14,
FLP6,
FLP13,
FLP10,
FLP2,
FLP1,
FLP3,
FLP9,
FLP12,
FLP4,
FLP7,
FLP5,
FLP19 The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00840160(coding)
ATGATAAAAAGAAACCCAAAAGAAAGGTAAAGCCCATTTGAAAAGCACTTTTACAGGCAC
TTATATAATGTTTAAATTACTTTAAATTAGCTAAATGAGAGTATTCGTTCAAGTAGAAAA
TAGAGATCTGAATAATAAAACTCTACTCAGCTTGTAAAAGTCAAAGAATGGTAGAATTAA
AGCGACGACGATGCAAATAAAAAAAAGGTTCACGAGAACAAAAATTAAAAAAAATCATTT
GTTCTGTTAAGGATTCTATTTCTAGTTTTAATATGGATTTTTGGAGTTGCTTTTTTAATG
AGAACAAAAACTTATAACAGCATAAGACTGTCTAAATCTGATTGGGAGCAACTTGTTGTA
AAACAATTTTCAAGAACATATTCCTTTAATAATTCTTTCTAATAAGAAGTGGAGAAGCTT
AACTAATTTAGCTTTGTTGATTATTGCATCGCAATGAAGGCTCAATGGTTATATGAACTT
AACCCATATTATAGCTCTACTATAGAATCTTAATTAAATAATTTATGGAAATTAGGATAA
AACAAAGTACATGATTTTTCTATTTTCGAAGTTAATTCTACTTTCATTTACTTTCGTGTT
TTTGAAATTAGAAGAAAGAAGGGTGCTTATAGCTTTAAGTTAGATATAACTTTTATTTAA
TATGATTTCAAAGAATTACAGAGAGTATATCTTAAATAAACTAACCAGCAATTAATAGAT
AAATAGACTTTTAATCACATATACCTCTAATTTAAAACCAGATAATCTAAAATAAATAAA
TAAATTCTGCCCGCCTAATAATCCAAAGCCAATAAAAGCTATTAGGTTTTCATGTCCAAC
AAAGAAGACGTTTACAATTCAAGTCTATTATATAATTCATCATAGGATTAAATATAATCC
TAACTGAATGAAAAGCTTCTTAACTAACCATCTTATTATATAATTTAAAATGAAGCAGAT
TTCTAGCATAGAAATATACCTAAAAATAATAAATTTCTTTGCTTTAGGAAGACTAAGTTT
GATTGGCAAGAATAGCCAGATAGATTAATTTAGACCAATGTATAGGATATGGAGGTTATT
GATAATTCTATTCACACTGCCAAATATAACTTTTTTTCCTTCATTCCTCTCAATCTCATG
GAGTAATTCTCTAAGCTTCCAAATGTCTACTTTCTATTGGTTGGATTTCTGCAAATGATT
GACGAAATTTCTAATTCAGAAGGCAGGCCCGTTATATTTTTCCCCTTGACTATCATTTTA
TGTGTAACAGCGATTAAAGATGCCTACGAAGATATGAAGAGGCACATGTATGATAAATAG
GAAAACAATAAACCTATTTTAGTAGCAAGAAACAAAAATTTTATGAAAGAGTAATGGAGA
AATTTAAGAATAGGAAATTTGATAAGAGTAAATAGAGATGAATATATTCCAGCAGATATT
ATTCTCATTTATTCTTCTAACAAAGGAGGAAATTGCTACGTTGAAACTAAAAATTTGGAT
GGAGAGACAAATCTAAAAGTAAAATCTGTACCAAAAAAACTACAGAGTGTATTTGAAACA
CAAAGCAAAATATTTAATACGTTTAGTGTCTGCAGATATGAGAAACCAAATCCATTTCTT
TATAAATTTTAAGGCTACATTGAATATGAACATTAGCTAAAGATGATCTAACAACCTCTC
GAAATAGGAAACTTTATTTTAAGAGGCTGCTCGCTTAAGTAAACTGATTATATAATAGGA
GTTGTGGCATACACTGGAAGTGATACAAAGATTATGCTCAACTCAGTTAAAGCTAGACCC
AAGCTAAGTACAATTTAAATCCTGATGAATTCTGAAATCATATTAGTATTTTTAGTCTAG
ATGCTATTTTGCATTGTGTGCGCTCTCTTAGAATAGAGCTGGACTGGAGACAATTTCTCA
AGCATTTAATTTTATTTAGGATTAACAGATAAAGATTAGAAGCATAATGATTCATTTATT
GGATTCCTAATCTACTATGGCATGTGGATGATGCTTTTCACGAATTTTGTTCCAATTTCT
TTGCTAGTAACTTTAGATATGGTGAAATTTTTTTAGTCTATGAAGATTACTAAGGATAAG
CACATGTTAGGGTAGGATGGATCAGAGCCCTTAGTTTAAAGTTCGGGTTTAAATGAAGAG
TTAGGATAAGTTGGATTCATATTTACTGATAAAACTGGAACTTTGACTTGCAATTAGTTA
GTTTTCAAAGCGTTTGGATTATAAGATAAAGTTTATGGGTTAGAAAAATGTCATTAATAG
GATAGGTTTTAAGATGATAAATATGATTAAGAGATGATTGAAATATAAAATATAGAGTTG
TAAAAATCAAAAAGATTTTAAGGTGCTGATTTTTATAAAGAATTTAATAGCTTTTCAAAC
AAAGAGAAGCTTGAAGATTTCATGATTTATTTAGCGATGTGCCATGAGATTATAGTTGAA
AATGATAAAGAGAAATTGATTTATAATGCATGCTCTCCTGATGATTTGTGTCTAGTAGAA
TTTGCAAAAGAATAAGGATTTGAGCTTCTGGGAATGGATCATGAAAATATTTTATCAATT
AAAAAAAAGCTATAAAATGAATAAGAAGAAATATTTAAATTTAAAATATTAAACATATTA
CCTTTCTCAAGTGCTCGAAAAAGAATGTCTATTATTTATTAAAAAATATTAACAAATTCA
AACAATATAGACGTTGTATAGGAAGAAATATACATTTCTACTAAGGGAGCTGATTCAATT
ATTATGAGTAGATTAGACTAAAAATAATAAGACTAATTTGTTTTGTAGAAAACTCATGAT
TTTTTAATTGAATTCGCTAAACTTGGATACAGAACTCTTGTACTTGCAAAAGGAAGAGTC
GACAATAATTTTTATGTTTAATGGAGTGAAAAAATGCATTAGTCTTAAATAATTCTAACT
TCTGAACGAGACGAAATAGTAGAAAAAGTAAGTGACGAAATAGAGTAAAACCTAATATTG
TATGGCTGCACAGCAATAGAAGATAAATTGTAAGAAAATGTTCCTCAAACAATTTAAAAA
TTAAGAGAAGCTGGAATTTAGATTTGGATGCTAACTGGTGATAAAAGGGAAACAGCAATA
AATGTTGGTCTACTGAGTTCAATCATAGAGCCTTCTTACAAAAGAGTAGTTTTAGACTTT
GAATTCAGCAAGTATTAAGATATCTTAGCTCTTTTAAAACAAGCAAAAAAAGAAGTAAAT
TAATTCATTTTATTTAAGAAATAATTTAAGTTATTCTAAAAGCTTCTTTCGTGTGAAGAG
GGTAGAAAAACAGCTTTGATCGTGAGTGGAGTCTCTCTTGATTAAATGTCGCACTAACCT
ATTGAAACTCATTCAGATGAATTGCTTACACTTTTCATGAAACTTGCTCAATATGTCGAT
TCCGTAATTGTGTGCAGAGTTTCTCCCAAACAAAAAAGATAAATTGTTGATTTATTTAGA
TAAAAGAACCCTGGAGCAACCACTTTAGCAATAGGAGATGGTGCCAACGATGTAAATATG
ATTATAGGTGCACATGTAGGAATAGGTATAAAGGGATTAGAGGGAACCTAAGCAGCTAGA
GCAAGCGATTTTGCAATAAATGAATTTTAGCAATTGGGTAGATTGTTGCTCTACTATGGT
AGGGAATTTTACAGAAAGAATAGCAATTTAGTCCTCTATAATTTTTACAAGAACATTTTA
GTTGTACTTCCATAGTTTTGGTATGGCTTTTACAATGGATTTTCTGCTTAGTTTTTATAC
GATCTTTGGATTTTCTAAATGTATAATATAATATTTACCTCAGCTCCTATTGTAGTTTTC
GCTTTATTTGATAAAGAATATAAAGGAAAATTTCTCTAACAAAATCCATATCCCTACTAC
TTAAGTGGTATATTAAATGAGTGCTTTGATAAAAAGACTTTTTGGTAATAATTTTTAATT
GCTATCCTTTAATCAGCCTTGATAGGTGCTTGCTGTATTTAAATCTTTGACACATCACTT
GACAACTTGGATACATATATGCTTCTAGTAGGAAACTTTATGTATTCAAATGTGATCATC
ATTTCTAACATAAAAATATTCTTAATTTCAAAATGTATAACACCTCTATTGATAGCATTT
ACATTAGGAAGTATCATCGTGTATTTCATTATATTCAAGCTTCTAAATTCTCTAGTTTTT
TTAGATGGATACCATATATTTGATAGATTATATGGATAAGTAGAAGTTTGGCTTGGACAT
ATTTTTATAGTAATTGCATGCCTCCTGATTGATTATGTCATAATAAACTTTAAAAGAATT
ACAGTTCAGCTCAATTAGAGTGAAGAGTCTATTAAAAGGATAATTTAAATACCATTTCAA
AAGATAAGACTTTCATACAGCGTCAATTAAAACTAGAGCGAATACTCTTCATCATCAAGG
ATGATAGAAATGAATGAAATTAAATCATTTTCACAAAGAGCAAGTATATAAAATTAGCAG
CCTTAATATTTTTCCTAGAGAAATAGTAGTCATGTACTGATAGGCACTCCATAAAACTAA
CAGCAACAACAATTTTTTAGTCCTAGTTCAAGATCTTTCAATAATTTAAATTAAAGTTTT
AATAAAATTTAAAAATGA

>TTHERM_00840160(protein)
MIKRNPKERQSPFEKHFYRHLYNVQITLNQLNESIRSSRKQRSEQQNSTQLVKVKEWQNQ
SDDDANKKKVHENKNQKKSFVLLRILFLVLIWIFGVAFLMRTKTYNSIRLSKSDWEQLVV
KQFSRTYSFNNSFQQEVEKLNQFSFVDYCIAMKAQWLYELNPYYSSTIESQLNNLWKLGQ
NKVHDFSIFEVNSTFIYFRVFEIRRKKGAYSFKLDITFIQYDFKELQRVYLKQTNQQLID
KQTFNHIYLQFKTRQSKINKQILPAQQSKANKSYQVFMSNKEDVYNSSLLYNSSQDQIQS
QLNEKLLNQPSYYIIQNEADFQHRNIPKNNKFLCFRKTKFDWQEQPDRLIQTNVQDMEVI
DNSIHTAKYNFFSFIPLNLMEQFSKLPNVYFLLVGFLQMIDEISNSEGRPVIFFPLTIIL
CVTAIKDAYEDMKRHMYDKQENNKPILVARNKNFMKEQWRNLRIGNLIRVNRDEYIPADI
ILIYSSNKGGNCYVETKNLDGETNLKVKSVPKKLQSVFETQSKIFNTFSVCRYEKPNPFL
YKFQGYIEYEHQLKMIQQPLEIGNFILRGCSLKQTDYIIGVVAYTGSDTKIMLNSVKARP
KLSTIQILMNSEIILVFLVQMLFCIVCALLEQSWTGDNFSSIQFYLGLTDKDQKHNDSFI
GFLIYYGMWMMLFTNFVPISLLVTLDMVKFFQSMKITKDKHMLGQDGSEPLVQSSGLNEE
LGQVGFIFTDKTGTLTCNQLVFKAFGLQDKVYGLEKCHQQDRFQDDKYDQEMIEIQNIEL
QKSKRFQGADFYKEFNSFSNKEKLEDFMIYLAMCHEIIVENDKEKLIYNACSPDDLCLVE
FAKEQGFELLGMDHENILSIKKKLQNEQEEIFKFKILNILPFSSARKRMSIIYQKILTNS
NNIDVVQEEIYISTKGADSIIMSRLDQKQQDQFVLQKTHDFLIEFAKLGYRTLVLAKGRV
DNNFYVQWSEKMHQSQIILTSERDEIVEKVSDEIEQNLILYGCTAIEDKLQENVPQTIQK
LREAGIQIWMLTGDKRETAINVGLLSSIIEPSYKRVVLDFEFSKYQDILALLKQAKKEVN
QFILFKKQFKLFQKLLSCEEGRKTALIVSGVSLDQMSHQPIETHSDELLTLFMKLAQYVD
SVIVCRVSPKQKRQIVDLFRQKNPGATTLAIGDGANDVNMIIGAHVGIGIKGLEGTQAAR
ASDFAINEFQQLGRLLLYYGREFYRKNSNLVLYNFYKNILVVLPQFWYGFYNGFSAQFLY
DLWIFQMYNIIFTSAPIVVFALFDKEYKGKFLQQNPYPYYLSGILNECFDKKTFWQQFLI
AILQSALIGACCIQIFDTSLDNLDTYMLLVGNFMYSNVIIISNIKIFLISKCITPLLIAF
TLGSIIVYFIIFKLLNSLVFLDGYHIFDRLYGQVEVWLGHIFIVIACLLIDYVIINFKRI
TVQLNQSEESIKRIIQIPFQKIRLSYSVNQNQSEYSSSSRMIEMNEIKSFSQRASIQNQQ
PQYFSQRNSSHVLIGTPQNQQQQQFFSPSSRSFNNLNQSFNKIQK

>TTHERM_00840160(gene)
ATGATAAAAAGAAACCCAAAAGAAAGGTAAAGCCCATTTGAAAAGCACTTTTACAGGCAC
TTATATAATGTTTAAATTACTTTAAATTAGCTAAATGAGAGTATTCGTTCAAGTAGAAAA
TAGAGATCTGAATAATAAAACTCTACTCAGCTTGTAAAAGTCAAAGAATGGTAGAATTAA
AGCGACGACGATGCAAATAAAAAAAAGGTTCACGAGAACAAAAATTAAAAAAAATCATTT
GTTCTGTTAAGGATTCTATTTCTAGTTTTAATATGGATTTTTGGAGTTGCTTTTTTAATG
AGAACAAAAACTTATAACAGCATAAGACTGTCTAAATCTGATTGGGAGCAACTTGTTGTA
AAACAATTTTCAAGAACATATTCCTTTAATAATTCTTTCTAATAAGAAGTGGAGAAGCTT
AACTAATTTAGCTTTGTTGATTATTGCATCGCAATGAAGGCTCAATGGTTATATGAACTT
AACCCATATTATAGCTCTACTATAGAATCTTAATTAAATAATTTATGGAAATTAGGATAA
AACAAAGTACATGATTTTTCTATTTTCGAAGTTAATTCTACTTTCATTTACTTTCGTGTT
TTTGAAATTAGAAGAAAGAAGGGTGCTTATAGCTTTAAGTTAGATATAACTTTTATTTAA
TATGATTTCAAAGAATTACAGAGAGTATATCTTAAATAAACTAACCAGCAATTAATAGAT
AAATAGACTTTTAATCACATATACCTCTAGTAAAATACAATTGTAAAAAATCTTTTCTAA
AATGGTATTTAAGATCATTTATAATAGAAATTATGAATCTTTCTTAATTAAAATTGGAAT
TTTACTTCTGTTTCCAATATTTATCTATGTGTCTAACTTCTATAAATTTATTTTAGTTAA
TAACAATGAAACTTTTTTCATTATTTTCAGTTTAAAATTTAGAATTTAAATTTATTTTAT
CTCTCTCAAAAAGGTTCTTGAAAAAGTAAGTAAGCAATTTTAATAAAATATTAAATTTAA
ATGAAAATCGTTTTTTAAATTATTATTTGATTGGTTTAATTTATTAAAGCTTTAAAATTT
ATATTTTATATATTGACCAAATCAAATTTTAAAATTATTTTTTAATGAAATTATGATAAA
AAAAATTGATTTTACTGGTTTCCAGTTAAGAAAAAGCGAATTAGTAATTAATTCTAGATT
TAAAACCAGATAATCTAAAATAAATAAATAAATTCTGCCCGCCTAATAATCCAAAGCCAA
TAAAAGTAAAATTAATTTCTCAAAATTTAGAATCAAGAATAAATACTTTAAATGTGTTAT
GATAATTTTGAAATTGCTTGTTTTTTTAATTTTATTTAATATTTTACAAAGAATGCTTTA
GAAAATAAGTCTATTAAATAAAAATATAAAGATAATTTAACAAAATTTTTCAAGAAAGTC
AAATTCTTTTTTAGAACCAAAATATTTTGCTTTTAGATGAATGATAAAATAGTGAATGAT
GAAAAAAGATATTTTGTTTAATATTAAATAATGTTTATATTAAGAACTATAAGCTTTTTT
ATCTAATAAAATAGGGTTTTGGAGTATTTAAAAAAAGTCTATTAACTGCATTAAGAAATA
AATTAAAATAGTAAATTTTGTAGATAAAGTCTAAATTTTTTATATGTAAGACTTAATTAA
ATTTTTTAAAAAGAGTGTACGTAATTAAGTGAATCAATACAAATTTTAAAGATATTTTTT
CTAATTTGATGGGCAGTAAAAATATTAATAAAAAAGAAGAAATTTTTATTACTAAATTAG
TAAGCAATAAATGGTATTAGTTTATTCAAGGAATTAATAAAAACTGAGCAAGTTTGGATT
AAATAAATAATAAATTAAAAGAAATGAATTACTTGTTAAATAAATGATACATACATACTG
TTGTTAAAGTATCAAAAAAAGCAGAAAAATTTTGAAATTTTACTATTTTATTCATAAAGA
TAGCGAATAGAAGGAAATTTAATTAAAATTCAATAAAACTTTATACAACATTACAATAAA
CTTTAAGAAAAAATAAGAAAGGTATCAAAAGTTAAGTAAGGAGAAGAATAGATAGTACGA
TAGTAGGCTATTAGGTTTTCATGTCCAACAAAGAAGACGTTTACAATTCAAGTCTATTAT
ATAATTCATCATAGGATTAAATATAATCCTAACTGAATGAAAAGCTTCTTAACTAACCAT
CTTATTATATAATTTAAAATGAAGCAGATTTCTAGCATAGAAATATACCTAAAAATAATA
AATTTCTTTGCTTTAGGAAGACTAAGTTTGATTGGCAAGAATAGCCAGATAGATTAATTT
AGACCAATGTATAGGATATGGAGGTTATTGATAATTCTATTCACACTGCCAAATATAACT
TTTTTTCCTTCATTCCTCTCAATCTCATGGAGTAATTCTCTAAGCTTCCAAATGTCTACT
TTCTAGTAAATCATTATAAAATTCAGATTTAAGATATTTCTTACAAATTTTTAGGGAAAC
TCCACTTCTAAAAAATATTTTGCATCATTGATAAATTAAATATTTCATTATCCTTGATTT
TACAGTTTATTTTGAGCTGTAAATTGAAAAAATATTTAACTATTCAATAGTTGGTTGGAT
TTCTGCAAATGATTGACGAAATTTCTAATTCAGAAGGCAGGCCCGTTATATTTTTCCCCT
TGACTATCATTTTATGTGTAACAGCGATTAAAGATGCCTACGAAGATATGAAGAGGTAAA
TATTATTGACATTTAAATGCCCTTTTTATATATTTTTACAAAATGAAACTTTGTTACTTT
TACTTTGGCAGTAAAATATATCTGTTTATTTGTTGAAAAAAAAAAAATTAAATTTATTGT
TTCAAAATAATTCGTTTATATAAAATAATATAGGCACATGTATGATAAATAGGAAAACAA
TAAACCTATTTTAGTAGCAAGAAACAAAAATTTTATGAAAGAGTAATGGAGAAATTTAAG
AATAGGAAATTTGATAAGAGTAAACAAGCATTCATTTTACTAATATTTAGGAAAAATAAA
TCTAAAAAAGAAGTTATCAAAATATATTTTAAAAAAATTAGGTAAATAGAGATGAATATA
TTCCAGCAGATATTATTCTCATTTATTCTTCTAACAAAGGAGGAAATTGCTACGTTGAAA
CTAAAAATTTGGATGGAGAGACAAATCTAAAAGTAAAATCTGTACCAAAAAAACTACAGA
GTGTATTTGAAACACAAAGCAAAGTAATAAATAACTTTAAATGAAAACAATCAGAGATAA
GATTATATATTATAAAAATAGATATTTAATACGTTTAGTGTCTGCAGATATGAGAAACCA
AATCCATTTCTTTATAAATTTTAAGGCTACATTGAATATGAACATTAGCTAAAGATGATC
TAACAACCTCTCGAAATAGGAAACTTTATTTTAAGAGGCTGCTCGCTTAAGTAAACTGAT
TATATAATAGGAGTTGTGGCATACACTGGAAGTGATACAAAGATTATGCTCAACTCAGTT
AAAGCTAGACCCAAGCTAAGTACAATTTAAATCCTGATGAATTCTGAAATCATATTAGTA
TTTTTAGTCTAGATGCTATTTTGCATTGTGTGCGCTCTCTTAGAATAGAGCTGGACTGGA
GACAATTTCTCAAGCATTTAATTTTATTTAGGATTAACAGATAAAGATTAGAAGCATAAT
GATTCATTTATTGGATTCCTAATCTACTATGGCATGTGGATGATGCTTTTCACGTAATTA
TAAATAAATTTTCCAATAATAATTAATATATTTATTTAATAAATTTTTTACTTGATGAAA
AATATTACATTCATTCAAGTATGATAAAAATTTATAAATTTGTATTTTGATTTTTAATAT
GTTAAAATTTTAATATTAATAGGAATTTTGTTCCAATTTCTTTGCTAGTAACTTTAGATA
TGGTGAAATTTTTTTAGTCTATGAAGATTACTAAGGATAAGCACATGTTAGGGTAGGATG
GATCAGAGCCCTTAGTTTAAAGTTCGGGTTTAAATGAAGAGTTAGGATAAGTTGGATTCA
TATTTACTGATAAAACTGGAACTTTGACTTGCAATTAGTTAGTTTTCAAAGCGTTTGGAT
TATAAGATAAAGTTTATGGGTTAGAAAAATGTCATTAATAGGATAGGTTTTAAGATGATA
AATATGATTAAGAGATGATTGAAATATAAAATATAGAGTTGTAAAAATCAAAAAGATTTT
AAGGTGCTGATTTTTATAAAGAATTTAATAGCTTTTCAAACAAAGAGAAGCTTGAAGATT
TCATGATTTATTTAGCGATGTGCCATGAGATTATAGTTGAAAATGATAAAGAGAAATTGA
TTTATAATGCATGCTCTCCTGATGATTTGTGTCTAGTAGAATTTGCAAAAGAATAAGGAT
TTGAGCTTCTGGGAATGGATCATGAAAATATTTTATCAATTAAAAAAAAGCTATAAAATG
AATAAGAAGAAATATTTAAATTTAAAATATTAAACATATTACCTTTCTCAAGTGCTCGAA
AAAGAATGTCTATTATTTATTAAAAAATATTAACAAATTCAAACAATATAGACGTTGTAT
AGGAAGAAATATACATTTCTACTAAGGGAGCTGATTCAATTATTATGAGTAGATTAGACT
AAAAATAATAAGACTAGTAAATTTTTGGATATTATGAGACTTATTTTTATTCAGTATTTG
TTTTAATTCAAAAGATTTGTTTTGTAGAAAACTCATGATTTTTTAATTGAATTCGCTAAA
CTTGGATACAGAACTCTTGTACTTGCAAAAGGAAGAGTCGACAATAATTTTTATGTTTAA
TGGAGTGAAAAAATGCATTAGTCTTAAATAATTCTAACTTCTGAAGTAAGTTTTTTTGAG
TTTTTATATATATTTTATTTTGTTTTTGTGATAAAAGCGAGACGAAATAGTAGAAAAAGT
AAGTGACGAAATAGAGTAAAACCTAATATTGTATGGCTGCACAGCAATAGAAGATAAATT
GTAAGAAAATGTTCCTCAAACAATTTAAAAATTAAGAGAAGCTGGAATTTAGATTTGGAT
GCTAACTGGTGATAAAAGGGAAACAGCAATAAATGTTGGTCTACTGAGTTCAATCATAGA
GCCTTCTTACAAAAGAGTAGTTTTAGACTTTGAATTCAGCAAGTATTAAGATATCTTAGC
TCTTTTAAAACAAGCAAAAAAAGAAGTAAATTAATTCATTTTATTTAAGAAATAATTTAA
GTTATTCTAAAAGCTTCTTTCGTGTGAAGAGGGTAGAAAAACAGCTTTGATCGTGAGTGG
AGTCTCTCTTGATTAAATGTCGCACTAACCTATTGAAACTCATTCAGATGAATTGCTTAC
ACTTTTCATGAAACTTGCTCAATATGTCGATTCCGTAATTGTGTGCAGAGTTTCTCCCAA
ACAAAAAAGATAAATTGTTGATTTATTTAGATAAAAGGTAAAAAATCATTAAAATTAATA
TTTAATTTAATTTTTATTTCTAAAATTTTAGAACCCTGGAGCAACCACTTTAGCAATAGG
AGATGGTGCCAACGATGTAAATATGATTATAGGTGCACATGTAGGAATAGGTATAAAGGG
ATTAGAGGGAACCTAAGCAGCTAGAGTAAATTTTAATATATTTTTTGAGAAAACATATGA
TAATCATTAATATTAATATAAAATTAAAGGCAAGCGATTTTGCAATAAATGAATTTTAGC
AATTGGGTAGATTGTTGCTCTACTATGGTAGGGAATTTTACAGAAAGAATAGCAATTTAG
TCCTCTATAATTTTTACAAGAACATTTTAGTTGTACTTCCATAGTTTTGGTATGGCTTTT
ACAATGGATTTTCTGCTTAGTTTTTATACGATCTTTGGATTTTCTAAATGTATAATATAA
TATTTACCTCAGCTCCTATTGTAGTTTTCGCTTTATTTGATAAAGAATATAAAGGAAAAT
TTCTCTAACAAAATCCATATCCCTACTACTTAAGTGGTATATTAAATGAGTGCTTTGATA
AAAAGACTTTTTGGTAATAATTTTTAATTGCTATCCTTTAATCAGCCTTGATAGGTGCTT
GCTGTATTTAAATCTTTGACACATCACTTGACAACTTGGATACATATATGCTTCTAGTAG
GAAACTTTATGTATTCAAATGTGATCATCATTTCTAACATAAAAATATTCTTAATTTCAA
AATGTATAACACCTCTATTGATAGCATTTACATTAGGAAGTATCATCGTGTATTTCATTA
TATTCAAGCTTCTAAATTCTCTAGTTTTTTTAGATGGATACCATATATTTGATAGGTAAA
ACAAATATATTCTAAACTTCAAAAACTATAAAAACACACCATTAATTATATTTAAAAGAT
TATATGGATAAGTAGAAGTTTGGCTTGGACATATTTTTATAGTAATTGCATGCCTCCTGA
TTGATTATGTCATAATAAACTTTAAAAGTAAGTTATTTTTTAATATAAGAATAAATCCTA
ATTCAATTCTAATAAAAAAGGAATTACAGTTCAGCTCAATTAGAGTGAAGAGTCTATTAA
AAGGATAATTTAAATACCATTTCAAAAGATAAGACTTTCATACAGCGTGTACTCAAATCA
AAATAATAAAATTAATTTATTTTTTTATTAATTTTTTATATTTTAAAAGCAATTAAAACT
AGAGCGAATACTCTTCATCATCAAGGATGATAGAAATGAATGAAATTAAATCATTTTCAC
AAAGAGCAAGTATATAAAATTAGCAGCCTTAATATTTTTCCTAGAGAAATAGTAGTCATG
TACTGATAGGCACTCCATAAAACTAACAGCAACAACAATTTTTTAGTCCTAGTTCAAGAT
CTTTCAATAATTTAAATTAAAGTTTTAATAAAATTTAAAAATGAAAATTAATAAATAAAT
AAACAATTAATTAGATTAAAATTTCTTTTTACATATCAAGGATTTTAGAAATATAAATCA
ATTAACTAACG

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Tetrahymena Stock Center

Homologs (v.2006 protein sequences)

General Information

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Sequences

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Paragraph No	Gene Name	Paragraph Text
19	FLP11, FLP18, FLP17, FLP8, FLP16, FLP15, FLP14, FLP6, FLP13, FLP10, FLP2, FLP1, FLP3, FLP9, FLP12, FLP4, FLP7, FLP5, FLP19	The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).