Gene Model Identifier
TTHERM_00675850
Standard Name
LIA3
Aliases
PreTt11026 | 101.m00181
Description
a parallel G quadruplex-binding protein that regulates DNA elimination boundaries
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
No Data fetched for Gene Ontology Annotations
Tetrahymena Functional Genomics Database:
Signal Peptide Present?: No
TTHERM_00675850
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No Data fetched for StockID
(v.2006 protein sequences)
Source Identifier Score Description
Stentor Coeruleus SteCoe_20738 0
Tetrahymena borealis EI9_14253.1 9.997093137033517e-262 hypothetical protein (405 aa)
Paragraph No Gene Name Paragraph Text 112 LIA3 In cells lacking LIA3 (Ξ”LIA3), the excision of IESs bounded by specific G-rich polypurine tracts was impaired and imprecise, whereas the removal of IESs without such controlling sequences was unaffected. Lia3p binds to oligonucleotides containing these polypurine tracts, which form parallel G-quadruplex structures in vitro.
Ref:26950070 : Carle CM, Zaher HS, Chalker DL (2016) A Parallel G Quadruplex-Binding Protein Regulates the Boundaries of DNA Elimination Events of Tetrahymena thermophila. PLoS genetics 12(3):e1005842Ref:17519286 : Yao MC, Yao CH, Halasz LM, Fuller P, Rexer CH, Wang SH, Jain R, Coyne RS, Chalker DL (2007) Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. Journal of cell science 120(Pt 12):1978-89
>TTHERM_00675850(coding)ATG AAA TCT CAT TCA AAG AAA TAC CAA GTA ACA AAT AAT TTA GAT GCT GAC AAT GAA TTA TAT CCT CAA TCA CAA ATT TAG AGT TCC AAT AAT GAT TAG TAA ACT CAA CTG AAC AGT CAA GAA GAA AAT AAC CCT GAT ATG ATT GAA ACT GAA GAT ATA AAC TTT AAT CCA AAT AAC TCC AAT AAA CCA ACA AAT AGT TCT TAT AAA ATT CAA ACA ATA AAC TTA GAG AAT AAC AAT CTA GGT GAA AAT ACT TCG CAA TAG ACT TCA ACA ATT AAA AAA AAT ATC AAT AGC AAC AAT TAG AAT TCT ATT ATA GAA ACA ACC TAT TAG CAA GAT AAA TTC ATA AAT GGT GCA ATA ATT GCA ATT AGG TCT CAA AAT CTA GCT GTT AAG TAT ATT GTT GAC CAT ATT AAG GAA ATA ACA GAC AGA AAT TTG TCT GAA GCT TAT GTA AGA AAG ATA TGG GAT CAT TGG CTT AAA TAC AAA GAT ATT TAC TTC TCT TCA ACA CAT AAA ACA AGA CTC TAC ACA AAG CAT GAA GCC ATT CAA CTT TAT GAT GCT ATT TTT AAG CAA TAT AAT CCA ACT AAC TAA TCT TAA AGT ATT ATC CCT AAA ATC AAA GAA GTA TTG TAA AAA CAT GCT ATA ACA AAA AAA TTG TTT ATC AAC TAC TCA CAA TTC GAA GAA GTC AAA GGA CTA GAT ACT GAA GAA ACA TAT CTC TCA ATT AAA GAA GCT ATA GAC TCA GGT TAG TAA TCT GAT GAG CCA AAA TGG ATT GAT GTC AGT GTA AGA ATG ATG ATT TCA GCA AGC TAG TTT GAA TAC AAG AAA CAG ATT GAA ATT CAA TGT TTT AAT AAA CTT AAA AAT TAT TTG CAA TTT TCT TGT ATA TAA TTG GTT GGT GTA GTT ATG GGT GAA ACA CTT AAT GGA AGA GGA AAA TTC ATT TAT ATC CAT TGT AGA TAT GAT CAG TTA ATA CTA AAG AGG AAC AAG TAC TTG AAA AGA TTC TTG CTT GAA GTT ATT CCT GAC TGG TTT TAT TCT TAT AAC TGT GTG CAT AGT CAA AAA ATT GCT ATT TTT AAG TAC TCT AAA TTT TTA TAT CTC TAA CGC AAG ATA CTT GAG GAG TAA GAA AGA AAA AGA TTT ATT CCT AAT CCA GTC AAT CCT CAG ATA AAT CAA ACC AAT CGT TTT AAC AAT TCT AGT GCT ATA AAT ACC TCC CTT AAC ATT TCC TAT CAA TCA TCT GCT GTT CCT AAT ACG AGT AGT ATA CCT CTG AAC AGT TTA TTC TGA >TTHERM_00675850(protein)M K S H S K K Y Q V T N N L D A D N E L Y P Q S Q I Q S S N N D Q Q T Q L N S Q E E N N P D M I E T E D I N F N P N N S N K P T N S S Y K I Q T I N L E N N N L G E N T S Q Q T S T I K K N I N S N N Q N S I I E T T Y Q Q D K F I N G A I I A I R S Q N L A V K Y I V D H I K E I T D R N L S E A Y V R K I W D H W L K Y K D I Y F S S T H K T R L Y T K H E A I Q L Y D A I F K Q Y N P T N Q S Q S I I P K I K E V L Q K H A I T K K L F I N Y S Q F E E V K G L D T E E T Y L S I K E A I D S G Q Q S D E P K W I D V S V R M M I S A S Q F E Y K K Q I E I Q C F N K L K N Y L Q F S C I Q L V G V V M G E T L N G R G K F I Y I H C R Y D Q L I L K R N K Y L K R F L L E V I P D W F Y S Y N C V H S Q K I A I F K Y S K F L Y L Q R K I L E E Q E R K R F I P N P V N P Q I N Q T N R F N N S S A I N T S L N I S Y Q S S A V P N T S S I P L N S L F >TTHERM_00675850(gene)ATG AAA TCT CAT TCA AAG AAA TAC CAA GTA ACA AAT AAT TTA GAT GCT GAC AAT GAA TTA TAT CCT CAA TCA CAA ATT TAG AGT TCC AAT AAT GAT TAG TAA ACT CAA CTG AAC AGT CAA GAA GAA AAT AAC CCT GAT ATG ATT GAA ACT GAA GAT ATA AAC TTT AAT CCA AAT AAC TCC AAT AAA CCA ACA AAT AGT TCT TAT AAA ATT CAA ACA ATA AAC TTA GAG AAT AAC AAT CTA GGT GAA AAT ACT TCG CAA TAG ACT TCA ACA ATT AAA AAA AAT ATC AAT AGC AAC AAT TAG AAT TCT ATT ATA GAA ACA ACC TAT TAG CAA GAT AAA TTC ATA AAT GGT GCA ATA ATT GCA ATT AGG TCT CAA AAT CTA GCT GTT AAG TAT ATT GTT GAC CAT ATT AAG GAA ATA ACA GAC AGA AAT TTG TCT GAA GCT TAT GTA AGA AAG ATA TGG GAT CAT TGG CTT AAA TAC AAA GAT ATT TAC TTC TCT TCA ACA CAT AAA ACA AGA CTC TAC ACA AAG CAT GAA GCC ATT CAA CTT TAT GAT GCT ATT TTT AAG CAA TAT AAT CCA ACT AAC TAA TCT TAA AGT ATT ATC CCT AAA ATC AAA GAA GTA ATT ATC AAA AAA TCT TAT TTT AAC TAA AAA TTA TAT CCC TTT TGT TTT TTT AAA ACA ATC TAG GTA TTG TAA AAA CAT GCT ATA ACA AAA AAA TTG TTT ATC AAC TAC TCA CAA TTC GAA GAA GTC AAA GGA CTA GAT ACT GAA GAA ACA TAT CTC TCA ATT AAA GAA GCT ATA GAC TCA GGT TAG TAA TCT GAT GAG CCA AAA TGG TAT TTG CTT TTT ATA ATT TTT ATC TAT TTT AAG TGT TGT GTT TTT TTA TGT TAA ATT ATT AAA TAA TTT TCA TTT TAA ATT TAG GAT TGA TGT CAG TGT AAG AAT GAT GAT TTC AGC AAG CTA GTT TGA ATA CAA GAA ACA GAT TGA AAT TCA ATG TTT TAA TAA ACT TAA AAA TTA TTT GCA ATT TTC TTG TAT ATA ATT GGT TGG TGT AGT TAT GGG TGA AAC ACT TAA TGG AAG AGG AAA ATT CAT TTA TAT CCA TTG TAG ATA TGA TCA GTT AAT ACT AAA GAG GAA CAA GTA CTT GAA AAG ATT CTT GCT TGA AGT TAT TCC TGA CTG GTT TTA TTC TTA TAA CTG TGT GCA TAG TCA AAA AAT TGC TAT TTT TAA GTA CTC TAA ATT TTT ATA TCT CTA ACG CAA GAT ACT TGA GGA GTA AGA AAG AAA AAG ATT TAT TCC TAA TCC AGT CAA TCC TCA GAT AAA TCA AAC CAA TCG TTT TAA CAA TTC TAG TGC TAT AAA TAC CTC CCT TAA CAT TTC CTA TCA ATC ATC TGC TGT TCC TAA TAC GAG TAG TAT ACC TCT GAA CAG TTT ATT CTG A
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