Identifiers and Description

Gene Model Identifier

TTHERM_00648920

Standard Name

HIAP1 (Histone-interacting acidic protein 1)

Aliases

PreTt09206 | 94.m00124 | 3677.m00032

Description

conserved hypothetical protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF03066 ) Nucleoplasmin

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00648920

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17846.1	3.998052787723392e-80	hypothetical protein (277 aa)

General Information

Paragraph No	Gene Name	Paragraph Text
130	HIAP1	HIAP1 was identified as a high-confidence interacting partner of histones H2A/H2B and Hv1 in affinity purification followed by mass spectrometry experiments. HIAP1 shares sequence similarity with nucleoplasmin 1 (CNPL1 in Tetrahymena) due to stretches of acidic residues

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00648920(coding)
ATGTTTTGGGGAGCTTAAGTTCAGTTTAATCAAAAGTTTGTTCCAGAAAAGGAAGACTAT
GCTTATCTTCATTTAAGAAATGTTAGCACTTTATGGGCAAATGAAAAAATTAGCTTGGTT
TGCAATATTAAGAAGCAAGAAAACGGAGTCGAAGAAGAAATTGATATTGTTTTATGCCAT
TTAGATGAAAATAAAAATAGAAGTGCTCAGTTAAATCTTTACTTTGATTTAAAAAATTAA
GATATCAGCTTCAGTGTTATCGGAAAAGGAAGAGTCTGCTTGATGGGCTCTCTTGAGGCT
AAAGAGGGTAAGGCTCTCACAAACGAACTTGTAAAGAATTTAGGACCACAAATTGCTGAT
GCTAAAAAGAAAATGATTCTTGAGTTAGCAGGTCTTGTAAAAGATATGAAATAAAAAGGT
GGAAATCAAGAAGATGACGATGAGGATTTAGATGATGAAGAAGAATATGTAGAGGGTATG
GATCTTGAAAGTGATGATGAAGATGGTGAAGAAGATAACGAAGATGAAGAGGAAGTAGAA
AGTGAAATTAGTGATTAAGAAAATTAAATAGTAGAATAAAAAAAATCCTAATAAAGTCAA
AATCAATAAAAGAATAATAACAATAAAAATAATAAGTAAGCAAATAATTAGAACATTGGC
AAGAAGCCTATTTAAAACAAACCTGCTTAAAACTAAAATTAACAACAAAAGCAAAATAAA
TAGGAAAACAAAAATCAATAATAAAAAAACAATGGTTAGAATAAATAGTAAAATGGTAAG
AAAGGTGAATTCCAAATCACTTATAACTACAAACCTAAAAAGGAAGAAGAAATAGAAAAA
GACGAATTTGCTGCAATTTGA

>TTHERM_00648920(protein)
MFWGAQVQFNQKFVPEKEDYAYLHLRNVSTLWANEKISLVCNIKKQENGVEEEIDIVLCH
LDENKNRSAQLNLYFDLKNQDISFSVIGKGRVCLMGSLEAKEGKALTNELVKNLGPQIAD
AKKKMILELAGLVKDMKQKGGNQEDDDEDLDDEEEYVEGMDLESDDEDGEEDNEDEEEVE
SEISDQENQIVEQKKSQQSQNQQKNNNNKNNKQANNQNIGKKPIQNKPAQNQNQQQKQNK
QENKNQQQKNNGQNKQQNGKKGEFQITYNYKPKKEEEIEKDEFAAI

>TTHERM_00648920(gene)
ATGTTTTGGGGAGCTTAAGTTCAGTTTAATCAAAAGTTTGTTCCAGAAAAGGAAGACTAT
GCTTATCTTCATTTAAGAAATGTTAGCACTTTATGGGCAAATGAAAAAATTAGCTTGGTT
TGCAATATTAAGAAGCAAGAAAACGGAGTCGAAGAAGAAATTGATATTGTTTTATGCCAT
TTAGATGAAAATAAAAATAGAAGTGCTCAGTTAAATCTTTACTTTGATTTAAAAAATTAA
GATATCAGCTTCAGTGTTATCGGAAAAGGAAGAGTCTGCTTGATGGGCTCTCTTGAGGCT
AAAGAGGGTAAGGCTCTCACAAACGAACTTGTAAAGAATTTAGGACCACAAATTGCTGAT
GCTAAAAAGAAAATGATTCTTGAGTTAGCAGGTCTTGTAAAAGATATGAAATAAAAAGGT
GGAAATCAAGAAGATGACGATGAGGATTTAGATGATGAAGAAGAATATGTAGAGGGTATG
GATCTTGAAAGTGATGATGAAGATGGTGAAGAAGATAACGAAGATGAAGAGGAAGTAGAA
AGTGAAATTAGTGATTAAGAAAATTAAATAGTAGAATAAAAAAAATCCTAATAAAGTCAA
AATCAATAAAAGAATAATAACAATAAAAATAATAAGTAAGCAAATAATTAGAACATTGGC
AAGAAGCCTATTTAAAACAAACCTGCTTAAAACTAAAATTAACAACAAAAGCAAAATAAA
TAGGAAAACAAAAATCAATAATAAAAAAACAATGGTTAGAATAAATAGTAAAATGGTAAG
AAAGGTGAATTCCAAATCACTTATAACTACAAACCTAAAAAGGAAGAAGAAATAGAAAAA
GACGAATTTGCTGCAATTTGA