Identifiers and Description

Gene Model Identifier

TTHERM_00600780

Standard Name

MYO4  (MYOsin )

Aliases

PreTt22141 | 83.m00210 | 3685.m00102

Description

Type V myosin motor involved in actin-based transport of cargos

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

GBrowse

Gene Ontology Annotations

Cellular Component

Molecular Function

Domains

  • ( PF00784 ) MyTH4 domain
  • ( PF00063 ) Myosin head (motor domain)
  • ( PF00612 ) IQ calmodulin-binding motif
  • ( TIGR02886 ) anti-sigma F factor antagonist
  • ( TIGR03229 ) benzoate 1,2-dioxygenase, large subunit

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12.2%

TetraMine Data

TTHERM_00600780

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_14937.19.997093137033517e-262myosin head domain-containing
protein (1626 aa)
OxytrichaContig18292.0.g1086.001815994751712e-130Myosin head (motor domain)
DictyBaseDDB_G02744554.9988663627895604e-120myoI on chromosome: 2 position
4534415 to 4541848
WormBaseWBGene000020395.0021648428951944e-116locus:hum-6 Unconventional m
yosin heavy chain 6 status:P
artially_confirmed UniProt:P
91443 protein_id:CCD61190.1
SGDYAL029C2.000277046697593e-115MYO4 One of two type V myosin
motors (along with MYO2) invol
ved in actin-based transport o
f cargos; required for mRNA tr
ansport, including ASH1 mRNA,
and facilitating the growth an
d movement of ER tubules into
the growing bud along with She
3p

General Information

Paragraph NoGene NameParagraph Text
10MYO1,
MYO12,
MYO11,
MYO10,
MYO9,
MYO4 ,
MYO5,
MYO4,
MYO3,
MYO2,
MYO13
Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

  1. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
  2. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43

Sequences

>TTHERM_00600780(coding)
ATGAACGAAAATTAATGGATGATTAGCCAAGCCCCTTGCTGGTTTAAGCTTAGTGATAAA
AAAGAGGAAAAGAAATTGTTTTATAAAGGAAGGATAAAAGAATCAACAGCTAATTCTGAT
CAAGTATTGGTTTGTTATGAAAAAGATGAATCAAACTAGGGAGAGGTTATGATATCCAAA
CAAAATATTTTCCAAAGAGATGAAAATCAATAAAATTAGTTATTTGAGGACATGGTTAAT
ATGGCAACATTAAATGAGTCTGAATTAATCATCAACATTTAGAATAGATACTCTCAAGAT
TTAATATTCACATATATAGGTCCTACTCTAATAGTTATGAACCCTTATAAAAAACTAGAT
GAGCAGTTTAGCCCCAAAGTTATTTAGTCAATTAAAGATAATTTAAATTAGCAAAAGTAG
CTCTTTAGCTTATCTCAACAAAGTCCTCATATTTATGCAATAGCAGCTTTATCTTTCAAG
AATTTATTTTAGAACAATAAAAAGCAAGCCATAGTCATTAGTGGAGAGAGTGGTGCAGGT
AAAACTGAAAATGCAAAATATGCTATGAAGTTTTTAACTTAGCTAAGTAATAATTAAGAA
TAGAGTTCAAATATATAAAAAAGTGTAATTAGTATCGAAGATCGTATTCTTTCATGCAAT
CCTTTGTTAGAAGCGTTTGGTAATGCAAAAACAGTTCGTAATGACAACTCAAGTAGATTT
GGCAAATATGTTAAGATTTTAGTAAATAAATAGTAAAGAATAATAGGAGCTTTCATAACG
AAATATTTGTTAGAAAAAAGTCGTGTCATTCACTTAAGTGAGGGAGAAAGAAATTATCAT
ATATTTTATCATTTGCTAATAGGAGGAGACAAAAATATTATATAATAAGTCAGCTTAAGT
GGAAAAAAGGTTGAAGACTTTGTTTATTTAAACTAAAGTAGTTGTAGAAATTTAGAAAAT
ATGAATGACTAGGAAATGTTTTAGGGAATTTTAGATTCGCTAAGAAAAATGAATTTCTCA
GATAATCTAGAGCTTTCAATATTTAAATTACTTTCAGCAATTTTGTATTTGGGTAATATA
GAATTTGATGACAAAGAATATGATGTGAACACGCCTTGTAAAGTATAAAATGAAGATATG
TTATAAATAGTAGCCACTTTATTGTCAACAGATAGCAATCAACTTAAAGAATCGTTTATT
AAAAAAGCCAGACAAACTCCTGGTTCAATTATATATTCTCCAGTAACAAAAAATGAATGC
ATAAATAATAAAAATACTCTCAGCAAAGCTCTTTACGATAAATTATTTTCTTGGCTTGTA
GGCAAATTAAATGATGGAATAATACCTGAAGGCTAAGATTTGCAGAATTTAAAAAATAGC
GATATCTTAAATATTGGACTGCTGGATATTTTTGGATTTGAAAATTTCGAATTAAACTCA
TTTGAGTAAATGTGCATAAATTACACAAACGAATATCTATAATAGTTGTATATAGCTTAT
GTTTTCAAAAACGAAGAAAAGATTTTCATAGAAGACGGGCTTTCTAAATATCTTTCTAAT
TTGAGTTACTAGGACAATTAAGCCATATTAGATTTATTTGATACTAACAGCGGAATATTT
GCTCTTCTTAATGAAAGTTGCTTATTGAAAAACAGTACTGATACTACTTTTTTAACAAAA
ATAAAAGAATAAAATTAAAATAATAAAAAATTGATTTTTCCCAAGCTGATAAAATGTACT
TTCACTATATGTCATACTTAAAGCAATGTTGAATACAATGTTGAAGGATTTAGAGAAAAA
AACATGGATGAATTGAATTAGGAGATTTAGAATTGCATTTTAAACTCAAAAAATTAAGAT
ATTTTGGAAATTTTTAGCTTTGAAGAACAGTCCAGTTAAGACAAAAGTATGAATAGTTAA
TAAGGAAAATTTGTTTCTAATAACGCTAAAAATAAGTATTTGTGCTCAAAATTTAAACAA
TAAATGACTGAACTTATGGGTGAGCTTAATTCTTCAGATGTACACTTTGTTAGATGCATA
AAACCAAATGAAGAAAAGAAAAAAGATCATCTTATTCAAGGCTATGTGATGCAGTAAATA
AGATACTTAGGAGTTTTGGAGTCTATAGAAGTCAGAAAACATACATATCCAGTCAGAAAA
ACTTATCAAGCCTTCTTCATTTAATATAGGGTTTGCTCAGATGTTTTAGAATTTTCAAAA
AGAACAGATTATTAAAAATTATGTTAAGAAATTTTAATTGAGTGCTTTAAAAGCGTTTCT
GACAAATAAGTTTTATATGGATAGTCTAGGATATATCTCAAGCAGGAATTTGAAATTTAA
CTTGAGAAACTTAAATAAAATTGCATTAAAAAAAAACAAACAGCTGCTACTATATCCATC
CAAAAAATATTCAGAAGGCTTCAGTTAGAAAAAAAACAGAGAAAGAGTATTCAAATTATA
AGATCAATATTTAAATAAGTTTTGTTAAACCATTTGTATAAAGGTTTTGAGAAGATAAAA
TCTAAAGCTAAGGAATAAACTTTTATAAAATTCTATAAGAAAATAGATTATTTCTTTAAA
GTTAATAAAGCAATCTCTTTTTATGCTATAAAAGAGTTTTATCTCAAAGTTAAAGCTGTA
GAGGAAATAGAAAGGAAAAAATCTATTTATAGATAATAAGAAGACATAAAATTAAAGTAA
TAATCTTAATAAAATCTTACAAACTCAACTGATTAAAGCTCAAAAAGACTTTCCTAGACT
TAAAATAATAGCAATAATTTGTAATCGAATTCAATGAACCACAATATTATATTAAGCGAT
CAATATGATAAAAACTTTTCCACAAACATGAGCAATTCAGCCTATTTTACTTCTTAAGTT
GAACCAAATGGAGCAGTTATAGATTCTAACAAATTCTACTACCAAGATAATTAATAAAAT
CTCTATGTTACTAATTAGAACGTTGACATAAACAATTATAATACTAAAAATATCTAAGAC
TGGAATTAGTTTGCCTTTTAAGATCCAGACTAATTTGGTGATAACACAATTTTCATTCCA
AGACCAACAGAGGAAGAAAATTAGAATGCAGAGAAATTGGCTAAACTGTTATCTTCTAAC
TCTCCTGAAACAATAGAAGAAATTGATGAAAAAGCAGATGATTGCTACTTTAAGCTGGAA
GATATTGAAGTAGATTAATACCATGAGATTAAAAAGTTTGATATGATAGCCTTCTATAAA
CAACATTTAAATATAAGAAAAAATTATTTTGGGGTTAAAAAGGATGAAAAAGAAATACTT
TCTTATTAAAAAAAATGTCTGAGCAAAGGTACTCTAATATAAGTAAACGATGAAGAGAAA
AAGGCAGCCATTTCACACTTTTAATTCTTGCTAGAACTAATGAAATTAGAAAAATATGAC
GATTCTAAATTAGTATCTATCCACATTTAAGATTTGAATTTAGTCAGCCTGAAAAAATCG
ACTTAATTTTATAACGAAGTAACAACTCAAATCATAAAGTAGTTAAATAAAAATAAGAAA
GAATCTGAAAGTTATTTAATTCTTTAATATTTGAAGGTCTTCCTGTATTGTTTTACTCCT
GACGATGATTTTTTAAAGGCTTTAATGCATTTCCTCATTTTTTATTTATATGAAAACTAA
TGGAAAGATAACATGAAAATTAAAAACTACATACTTTATATAATTCCATCAATTATTAGA
AAAATAGATTAAGAGAATCCAAGGAAATAACTATTTACATTGCTCATCCCTTAGTACGAA
ATTAATGCATTAATTCTTTAGAATAAACTTTGTCTTCCTATTGCTTTTTGTACAGGTATA
AGCATTTAAGTCTGTGCAGATTCTTGGGACACAGTGGAGTAATTAAAGTAAAAGATCATG
AAGCAAGTATAGATAAATACTGACAGAATAAAACCGAATTACTTGCAACTTTTTGAGCTG
CAATTTATAGAGGAAAATAAAACAATTGAAAAAATGCTCTTGCCTGATCAGTATATTTGG
GATATTTTATATTTATAAAATCAAAAACAAATTTAAAAGGTTTAATCCATGAAAGAAAAA
GGAAATTATAATTAATAAATGTAGTAGAAAGAATCTGAACAGTATATTATATCAATATTT
ATGATTAAAGTTTTATTTCCTTTTACTCTCTATCCAGACGACATAGCAGGTATAAGCCTT
TAATTCAGCTAGGTATTTTTCGATATCTACGTGGGAAAATAAATCATAGATGAAGTAGAA
AAAATTATATAATTAAGTGCTTTACTTAAGATTATAAATAATTGCCACTCAGACCAAGAA
ACTATGAACTCTCTTCCATTAATTATGCAACAAGAATCTAGACAAGAAGTGATTGGACCT
ATCAATAAGGAGTACGAAAGAATTAAAGGTCTTTTCAATGTCCTCCAAGCAAAATATATG
TACTTGATGATTGCAAAAGATAATAAATACTATTTAGGTCTTTAAATCGAAGTGAAGTAT
ATTCCTCCTGAAATAGAAATTTAGGATTACTAATGTAAATTGAAAACCGAGTCTGAAAAC
GAATTTAATTGCAGCTATGTAGAAGTGATATTAGTACTAAAACCAACCTACTTTTTTATA
GTTACATCTGAAAGCAAAAAGATAATAATAGAATACTCATACTAAGACATAGAAAGGTGG
GGAAGAAGCAAATATGATCTTTAAGATCACATCCTTATTTAGACCAAAGGAGGAATCAAA
CACTTAATACAATCAAAATACTCTGCTTAAATATTATTCTATTTCTAAGAATCCAAAAAT
TTAATGTAATAGGCTTATAATAATATCATTGATGATGAAAATGAAGAGAATAGACTTGCA
AACAATCAATTAATTTAGTAATTTTTGGAATACTATTAAAATAACAATGAGCAAGAAAAT
TAATAATGA


>TTHERM_00600780(protein)
MNENQWMISQAPCWFKLSDKKEEKKLFYKGRIKESTANSDQVLVCYEKDESNQGEVMISK
QNIFQRDENQQNQLFEDMVNMATLNESELIINIQNRYSQDLIFTYIGPTLIVMNPYKKLD
EQFSPKVIQSIKDNLNQQKQLFSLSQQSPHIYAIAALSFKNLFQNNKKQAIVISGESGAG
KTENAKYAMKFLTQLSNNQEQSSNIQKSVISIEDRILSCNPLLEAFGNAKTVRNDNSSRF
GKYVKILVNKQQRIIGAFITKYLLEKSRVIHLSEGERNYHIFYHLLIGGDKNIIQQVSLS
GKKVEDFVYLNQSSCRNLENMNDQEMFQGILDSLRKMNFSDNLELSIFKLLSAILYLGNI
EFDDKEYDVNTPCKVQNEDMLQIVATLLSTDSNQLKESFIKKARQTPGSIIYSPVTKNEC
INNKNTLSKALYDKLFSWLVGKLNDGIIPEGQDLQNLKNSDILNIGLLDIFGFENFELNS
FEQMCINYTNEYLQQLYIAYVFKNEEKIFIEDGLSKYLSNLSYQDNQAILDLFDTNSGIF
ALLNESCLLKNSTDTTFLTKIKEQNQNNKKLIFPKLIKCTFTICHTQSNVEYNVEGFREK
NMDELNQEIQNCILNSKNQDILEIFSFEEQSSQDKSMNSQQGKFVSNNAKNKYLCSKFKQ
QMTELMGELNSSDVHFVRCIKPNEEKKKDHLIQGYVMQQIRYLGVLESIEVRKHTYPVRK
TYQAFFIQYRVCSDVLEFSKRTDYQKLCQEILIECFKSVSDKQVLYGQSRIYLKQEFEIQ
LEKLKQNCIKKKQTAATISIQKIFRRLQLEKKQRKSIQIIRSIFKQVLLNHLYKGFEKIK
SKAKEQTFIKFYKKIDYFFKVNKAISFYAIKEFYLKVKAVEEIERKKSIYRQQEDIKLKQ
QSQQNLTNSTDQSSKRLSQTQNNSNNLQSNSMNHNIILSDQYDKNFSTNMSNSAYFTSQV
EPNGAVIDSNKFYYQDNQQNLYVTNQNVDINNYNTKNIQDWNQFAFQDPDQFGDNTIFIP
RPTEEENQNAEKLAKLLSSNSPETIEEIDEKADDCYFKLEDIEVDQYHEIKKFDMIAFYK
QHLNIRKNYFGVKKDEKEILSYQKKCLSKGTLIQVNDEEKKAAISHFQFLLELMKLEKYD
DSKLVSIHIQDLNLVSLKKSTQFYNEVTTQIIKQLNKNKKESESYLILQYLKVFLYCFTP
DDDFLKALMHFLIFYLYENQWKDNMKIKNYILYIIPSIIRKIDQENPRKQLFTLLIPQYE
INALILQNKLCLPIAFCTGISIQVCADSWDTVEQLKQKIMKQVQINTDRIKPNYLQLFEL
QFIEENKTIEKMLLPDQYIWDILYLQNQKQIQKVQSMKEKGNYNQQMQQKESEQYIISIF
MIKVLFPFTLYPDDIAGISLQFSQVFFDIYVGKQIIDEVEKIIQLSALLKIINNCHSDQE
TMNSLPLIMQQESRQEVIGPINKEYERIKGLFNVLQAKYMYLMIAKDNKYYLGLQIEVKY
IPPEIEIQDYQCKLKTESENEFNCSYVEVILVLKPTYFFIVTSESKKIIIEYSYQDIERW
GRSKYDLQDHILIQTKGGIKHLIQSKYSAQILFYFQESKNLMQQAYNNIIDDENEENRLA
NNQLIQQFLEYYQNNNEQENQQ


>TTHERM_00600780(gene)
ATGAACGAAAATTAATGGATGATTAGCCAAGCCCCTTGCTGGTTTAAGCTTAGTGATAAA
AAAGAGGAAAAGAAATTGTTTTATAAAGGAAGGATAAAAGAATCAACAGCTAATTCTGAT
CAAGTATTGGTTTGTTATGAAAAAGATGAATCAAACTAGGGAGAGGTTATGATATCCAAA
CAAAATATTTTCCAAAGAGATGAAAATCAATAAAATTAGTTATTTGAGGACATGGTTAAT
ATGGCAACATTAAATGAGTCTGAATTAATCATCAACATTTAGAATAGATACTCTCAAGAT
TTAATATTCACATATATAGGTCCTACTCTAATAGTTATGAACCCTTATAAAAAACTAGAT
GAGCAGTTTAGCCCCAAAGTTATTTAGTCAATTAAAGATAATTTAAATTAGCAAAAGTAG
CTCTTTAGCTTATCTCAACAAAGTCCTCATATTTATGCAATAGCAGCTTTATCTTTCAAG
AATTTATTTTAGAACAATAAAAAGCAAGCCATAGTCATTAGTGGAGAGAGTGGTGCAGGT
AAATTTACATTTATTTTACTGAAATAACTAAACGCTTCTATTTATTTTACAAGAAGCATA
TTCTAGCAAATGCTTAGTATTCAATAAGCAACTTAGAATAAATTGTTTTTAGCATAATTT
AAAATTGATTTTATGAATGATCATAATTATTTTTTTAATAAAATAGGTAAAACTGAAAAT
GCAAAATATGCTATGAAGTTTTTAACTTAGCTAAGTAATAATTAAGAATAGAGTTCAAAT
ATATAAAAAAGTGTAATTAGTATCGAAGATCGTATTCTTTCATGCAATCCTTTGTTAGAA
GCGTTTGGTAATGCAAAAACAGTTCGTAATGACAACTCAAGTAGATTTGGCAAATATGTT
AAGATTTTAGTAAATAAATAGTAAAGAATAATAGGAGCTTTCATAACGAAATATTTGTTA
GAAAAAAGTCGTGTCATTCACTTAAGTGAGGGAGAAAGAAATTATCATATATTTTATCAT
TTGCTAATAGGAGGAGACAAAAATATTATATAATAAGTCAGCTTAAGTGGAAAAAAGGTT
GAAGACTTTGTTTATTTAAACTAAAGTAGTTGTAGAAATTTAGAAAATATGAATGACTAG
GAAATGTTTTAGGGAATTTTAGATTCGCTAAGAAAAATGAATTTCTCAGATAATCTAGAG
CTTTCAATATTTAAATTACTTTCAGCAATTTTGTATTTGGGTAATATAGAATTTGATGAC
AAAGAATATGATGTGAACACGCCTTGTAAAGTATAAAATGAAGATATGTTATAAATAGTA
GCCACTTTATTGTCAACAGATAGCAATCAACTTAAAGAATCGTTTATTAAAAAAGCCAGA
CAAACTCCTGGTTCAATTATATATTCTCCAGTAACAAAAAATGAATGCATAAATAATAAA
AATACTCTCAGCAAAGCTCTTTACGATAAATTATTTTCTTGGCTTGTAGGCAAATTAAAT
GATGGAATAATACCTGAAGGCTAAGATTTGCAGAATTTAAAAAATAGCGATATCTTAAAT
ATTGGACTGCTGGATATTTTTGGATTTGAAAATTTCGAATTAAACTCATTTGAGTAAATG
TGCATAAATTACACAAACGAATATCTATAATAGTTGTATATAGCTTATGTTTTCAAAAAC
GAAGAAAAGATTTTCATAGAAGACGGGCTTTCTAAATATCTTTCTAATTTGAGGTAAAAA
CTGTTTGAATTTTAATTAATTAATTTTGCTTACTAAAAAATATATGGTTATTCAAGTTAG
TAAATTTTTTCTATCGAAATTGAGAAAAATTTTTTATTTTTTATAATTGCCAAAAAAATT
AATTGATTTATATGTAGTTTTTAGAAATAAAAGAAAGCTTCATATGTTAAATAAAATTAA
TTATTTAGTTTTACTTTAGTTTCATAATATTTTATGATATAGTTACTAGGACAATTAAGC
CATATTAGATTTATTTGATACTAACAGCGGAATATTTGCTCTTCTTAATGAAAGTTGCTT
ATTGAAAAACAGTACTGATACTACTTTTTTAACAAAAATAAAAGAATAAAATTAAAATAA
TAAAAAATTGATTTTTCCCAAGCTGATAAAATGTACTTTCACTATATGTCATACTTAAAG
CAATGTTGAATACAATGTTGAAGGATTTAGAGAAAAAAACATGGATGAATTGAATTAGGA
GATTTAGAATTGCATTTTAAACTCAAAAAATTAAGATATTTTGGAAATTTTTAGCTTTGA
AGAACAGTCCAGTTAAGACAAAAGTATGAATAGTTAATAAGGAAAATTTGTTTCTAATAA
CGCTAAAAATAAGTATTTGTGCTCAAAATTTAAACAATAAATGACTGAACTTATGGGTGA
GCTTAATTCTTCAGATGTACACTTTGTTAGATGCATAAAAGTAAAAAAATTTATTTAAAA
GATTAAAATTATTGATCATTTATTATTTTTTTGTTAGCCAAATGAAGAAAAGAAAAAAGA
TCATCTTATTCAAGGCTATGTGATGCAGTAAATAAGATACTTAGGAGTTTTGGAGTCTAT
AGAAGTCAGAAAACATACATATCCAGTCAGAAAAACTTATCAAGCCTTCTTCATTTAATA
TAGGGTTTGCTCAGATGTTTTAGAATTTTCAAAAAGAACAGATTATTAAAAATTATGTTA
AGAAATTTTAATTGAGTGCTTTAAAAGCGTTTCTGACAAATAAGTTTTATATGGATAGTC
TAGGATATATCTCAAGCAGGAATTTGAAATTTAACTTGAGAAACTTAAATAAAATTGCAT
TAAAAAAAAACAAACAGCTGCTACTATATCCATCCAAAAAATATTCAGAAGGCTTCAGTT
AGAAAAAAAACAGAGAAAGAGTATTCAAATTATAAGATCAATATTTAAATAAGTTTTGTT
AAACCATTTGTATAAAGGTTTTGAGAAGATAAAATCTAAAGCTAAGGAATAAACTTTTAT
AAAATTCTATAAGAAAATAGATTATTTCTTTAAAGTTAATAAAGCAATCTCTTTTTATGC
TATAAAAGAGTTTTATCTCAAAGTTAAAGCTGTAAAAAAATATTATTTTTTTTTAAATTA
ATTTATTTATGAAAAAAATAATAAAATAGGTAGAGGAAATAGAAAGGAAAAAATCTATTT
ATAGATAATAAGAAGACATAAAATTAAAGTAATAATCTTAATAAAATCTTACAAACTCAA
CTGATTAAAGCTCAAAAAGACTTTCCTAGACTTAAAATAATAGCAATAATTTGTAATCGA
ATTCAATGAACCACAATATTATATTAAGCGATCAATATGATAAAAACTTTTCCACAAACA
TGAGCAATTCAGCCTATTTTACTTCTTAAGTTGAACCAAATGGAGCAGTTATAGATTCTA
ACAAATTCTACTACCAAGATAATTAATAAAATCTCTATGTTACTAATTAGAACGTTGACA
TAAACAATTATAATACTAAAAATATCTAAGACTGGAATTAGTTTGCCTTTTAAGATCCAG
ACTAATTTGGTGATAACACAATTTTCATTCCAAGACCAACAGAGGAAGAAAATTAGAATG
CAGAGAAATTGGCTAAACTGTTATCTTCTAACTCTCCTGAAACAATAGAAGAAATTGATG
AAAAAGCAGATGATTGCTACTTTAAGCTGGAAGATATTGAAGTAGATTAATACCATGAGA
TTAAAAAGTTTGATATGATAGCCTTCTATAAACAACATTTAAATATAAGAAAAAATTATT
TTGGGGTTAAAAAGGATGAAAAAGAAATACTTTCTTATTAAAAAAAATGTCTGAGCAAAG
GTACTCTAATATAAGTAAACGATGAAGAGAAAAAGGCAGCCATTTCACACTTTTAATTCT
TGCTAGAACTAATGAAATTAGAAAAATATGACGATTCTAAATTAGTATCTATCCACATTT
AAGATTTGAATTTAGTCAGCCTGAAAAAATCGACTTAATTTTATAACGAAGTAACAACTC
AAATCATAAAGTAGTTAAATAAAAATAAGAAAGAATCTGAAAGTTATTTAATTCTTTAAT
ATTTGAAGGTCTTCCTGTATTGTTTTACTCCTGACGATGATTTTTTAAAGGCTTTAATGC
ATTTCCTCATTTTTTATTTATATGAAAACTAATGGAAAGATAACATGAAAATTAAAAACT
ACATACTTTATATAATTCCATCAATTATTAGAAAAATAGATTAAGAGAATCCAAGGAAAT
AACTATTTACATTGCTCATCCCTTAGTACGAAATTAATGCATTAATTCTTTAGAATAAAC
TTTGTCTTCCTATTGCTTTTTGTACAGGTAATCAAAAATAAATAAAAAAAATTTTATCAA
AACTTAAAATTAATAAAAAATAGGTATAAGCATTTAAGTCTGTGCAGATTCTTGGGACAC
AGTGGAGTAATTAAAGTAAAAGATCATGAAGCAAGTATAGATAAATACTGACAGAATAAA
ACCGAATTACTTGCAACTTTTTGAGCTGCAATTTATAGAGGAAAATAAAACAATTGAAAA
AATGCTCTTGCCTGATCAGTATATTTGGGATATTTTATATTTATAAAATCAAAAACAAAT
TTAAAAGGTTTAATCCATGAAAGAAAAAGGAAATTATAATTAATAAATGTAGTAGAAAGA
ATCTGAACAGTATATTATATCAATATTTATGATTAAAGTTTTATTTCCTTTTACTCTCTA
TCCAGACGACATAGCAGGTATAAGCCTTTAATTCAGCTAGGTATTTTTCGATATCTACGT
GGGAAAATAAATCATAGATGAAGTAGAAAAAATTATATAATTAAGTGCTTTACTTAAGAT
TATAAATAATTGCCACTCAGACCAAGAAACTATGAACTCTCTTCCATTAATTATGCAACA
AGAATCTAGACAAGAAGTGATTGGACCTATCAATAAGGAGTACGAAAGAATTAAAGGTCT
TTTCAATGTCCTCCAAGCAAAATATATGTACTTGATGATTGCAAAAGATAATAAATACTA
TTTAGGTCTTTAAATCGAAGTGAAGTATATTCCTCCTGAAATAGAAATTTAGGATTACTA
ATGTAAATTGAAAACCGAGTCTGAAAACGAATTTAATTGCAGCTATGTAGAAGTGATATT
AGTACTAAAACCAACCTACTTTTTTATAGTTACATCTGAAAGCAAAAAGATAATAATAGA
ATACTCATACTAAGACATAGAAAGGTGGGGAAGAAGCAAATATGATCTTTAAGATCACAT
CCTTATTTAGACCAAAGGAGGAATCAAACACTTAATACAATCAAAATACTCTGCTTAAAT
ATTATTCTATTTCTAAGAATCCAAAAATTTAATGTAATAGGCTTATAATAATATCATTGA
TGATGAAAATGAAGAGAATAGACTTGCAAACAATCAATTAATTTAGTAATTTTTGGAATA
CTATTAAAATAACAATGAGCAAGAAAATTAATAATGA