Identifiers and Description

Gene Model Identifier

TTHERM_00561799

Standard Name

TKU71

Aliases

3720.m00655

Description

TKU70 ATP-dependent DNA helicase II 70 kDa subunit (Ku70); DNA-dependent ATP-dependent helicase; homolog to human KU70 DNA helicase and yeast YKU70

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• ATP-dependent DNA helicase activity (IEA) | GO:0004003
• DNA binding (IEA) | GO:0003677
• nucleic acid binding (IEA) | GO:0003676

Biological Process

• double-strand break repair via nonhomologous end joining (IEA) | GO:0006303

Domains

• ( PF02037 ) SAP domain
• ( TIGR02772 ) Ku protein
• ( PF03730 ) Ku70/Ku80 C-terminal arm
• ( PF02735 ) Ku70/Ku80 beta-barrel domain
• ( PF00092 ) von Willebrand factor type A
• ( PF03731 ) Ku70/Ku80 N-terminal alpha/beta domain
• ( TIGR00578 ) ATP-dependent DNA helicase ii, 70

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00561799

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_16104.1	9.997093137033517e-262	ku P70 DNA helicase (716 aa)
Oxytricha	Contig17155.0.g65	5.998305401373361e-129	Ku70/Ku80 beta-barrel domain
DictyBase	DDB_G0286069	3.0000115468388957e-66	ku70 on chromosome: 4 position 4023180 to 4025992
Stentor Coeruleus	SteCoe_1293	1.6889118802245324e-48
SGD	YMR284W	0.000000030002053728821195	YKU70 Subunit of the telomeric Ku complex (Yku70p-Yku80p), i nvolved in telomere length mai ntenance, structure and telome re position effect; relocates to sites of double-strand clea vage to promote nonhomologous end joining during DSB repair

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000249

Sequences

>TTHERM_00561799(protein)
MEFDEFEDDFVGGDAGEGGDQAQGFDFQENEFIPDLISKKDAVIFLIDCNKKIFQNEFND
EVQFKVILKSIQSFFKSKIISSLDDQVSVIFYNVKQTNNDLNFKGINIVYNLSTPSAEMI
KNVVKLGDNFERDFGFADNETPFHEALWTCNSIFTKLDSKKFIMRIFLFTNNDQPHSDNK
DFLDKCFNQARTLAEKNIQIELFPLATRNQKFDIRKFYSSIITFDVDEINEAVIDTSDKV
LDIQHRLRQKEYKKRAVNRLLFTLGDETRLGVKLFCPFVKQRRPLAKQLESNTNKLLKRT
VKHICKETGQSLYQNQISTCVHIGGEKVKVSKGDINEIKSFEEPGMRLIGFKPSGTLKAY
HNYRTSYFVYPDDYHVKGSSQSFHALISQMIAKDKIAIVRFIPRKGTQVRFCALLPQEES
YDEDHVQTPPGFHLIFLPYADDQRNLGSIRPQQKEEVSRNLLNAAKMMCNALDLANFDFR
NFEDPSLQKFFAHLQAHALQEENPENPADLIQPDEEGMKRCEDIIKLFEEALKLDVQDDD
QPQAAQKKPRQKKVAVEKQPAAQKKQPAPKKPAQNKKQVKKEEESEASSIGDYDSEDSFI
DNEEDEIKPKKRGVQNKKVTNQRKVNKKVEYSDEDDEISYEEKPKRKAAGKKQMSEEEKL
ISHVEANLKEEFNPDGLTISELKQYLKFKGLKNVGKKEELVDTILRHLERN

>TTHERM_00561799(coding)
ATGGAATTTGATGAATTTGAAGATGACTTCGTCGGCGGAGACGCTGGAGAAGGTGGTGAC
CAAGCTTAGGGATTTGATTTCTAGGAAAACGAATTTATTCCTGATCTCATAAGTAAAAAA
GATGCAGTCATCTTTTTAATTGACTGCAACAAGAAGATCTTCCAAAACGAGTTTAATGAT
GAAGTTTAGTTTAAAGTAATACTAAAGAGTATTTAGAGTTTCTTCAAGTCAAAGATTATT
TCAAGTTTAGATGACTAAGTTTCTGTTATTTTCTACAATGTGAAACAAACAAATAATGAT
TTGAACTTTAAGGGGATCAATATAGTTTATAATCTTAGCACTCCTTCAGCAGAAATGATT
AAAAACGTAGTTAAGTTAGGAGATAATTTTGAAAGAGATTTCGGTTTTGCAGACAATGAA
ACACCTTTCCACGAAGCATTGTGGACTTGCAATAGCATTTTTACAAAATTAGATAGTAAA
AAATTTATAATGAGAATATTCCTATTCACCAACAATGATTAGCCCCATTCAGATAATAAA
GATTTTTTAGATAAGTGCTTTAACTAAGCAAGAACTTTGGCAGAAAAGAATATCTAAATT
GAGTTGTTCCCTCTTGCTACTAGAAACTAAAAGTTTGATATCAGAAAATTCTATTCAAGC
ATCATTACCTTTGATGTAGATGAAATTAATGAAGCTGTTATCGATACATCAGATAAAGTT
TTGGATATCCAACACAGATTACGTCAAAAAGAATACAAAAAAAGGGCAGTCAACAGATTA
CTTTTTACTTTGGGTGATGAAACTAGATTGGGAGTCAAATTGTTTTGCCCATTCGTGAAA
TAAAGACGCCCTCTTGCCAAATAATTAGAATCTAACACTAATAAACTTTTAAAAAGGACA
GTAAAGCATATTTGCAAAGAAACAGGTTAGTCTTTATATCAAAACCAAATTTCCACATGT
GTTCACATTGGAGGAGAGAAGGTTAAAGTTAGTAAAGGTGATATTAATGAAATCAAATCA
TTCGAAGAACCAGGTATGCGTTTAATAGGATTTAAACCTTCAGGAACACTTAAGGCTTAC
CACAACTATAGAACAAGCTACTTTGTTTACCCAGATGATTATCATGTAAAGGGATCATCT
CAATCTTTTCATGCTTTGATCTCATAAATGATTGCCAAAGATAAAATAGCTATTGTTAGA
TTCATTCCCCGTAAAGGCACTTAGGTTAGGTTCTGTGCTTTACTTCCATAAGAAGAAAGT
TATGATGAAGACCATGTTTAAACACCTCCAGGCTTTCATTTGATTTTCTTACCATATGCT
GATGATTAGAGAAATTTAGGTTCCATCAGACCTTAATAAAAGGAAGAAGTTAGCAGAAAT
TTACTAAATGCAGCTAAAATGATGTGCAATGCATTAGATTTAGCTAATTTTGATTTTAGA
AATTTCGAAGATCCTTCACTATAGAAATTTTTTGCTCATCTTCAGGCACATGCCTTATAA
GAAGAAAACCCAGAAAATCCAGCAGACTTGATCTAACCTGATGAAGAAGGTATGAAACGC
TGTGAAGATATAATTAAGCTATTTGAAGAAGCATTGAAGTTAGATGTATAAGATGATGAC
CAACCTCAAGCCGCTTAAAAAAAACCAAGATAAAAAAAGGTAGCTGTTGAAAAGTAACCT
GCTGCACAAAAGAAATAACCTGCTCCAAAAAAGCCTGCTTAAAACAAAAAATAAGTAAAA
AAAGAAGAAGAGTCTGAAGCAAGCAGTATAGGTGATTATGACTCTGAGGACTCCTTTATC
GATAATGAAGAAGATGAAATTAAGCCTAAAAAAAGAGGAGTTTAAAACAAAAAAGTGACT
AATTAAAGAAAAGTTAATAAAAAAGTTGAATACAGTGATGAAGATGATGAGATAAGCTAT
GAAGAAAAACCAAAACGAAAAGCAGCAGGGAAGAAACAAATGAGCGAAGAAGAAAAACTT
ATTTCACATGTAGAAGCTAATTTAAAAGAAGAATTCAACCCAGATGGTTTGACAATATCT
GAGCTTAAATAGTATCTTAAGTTCAAAGGACTTAAAAATGTTGGTAAAAAGGAAGAATTG
GTTGATACCATTTTAAGACACTTAGAAAGAAATTGA

>TTHERM_00561799(gene)
ATGGAATTTGATGAATTTGAAGATGACTTCGTCGGCGGAGACGCTGGAGAAGGTGGTGAC
CAAGCTTAGGGATTTGATTTCTAGGAAAACGAAGTACTTTAAAAATTATTTGCTATTTTT
TTAGTAAGAAACACAATAACATAAAAAATAAAAAGTTTATTCCTGATCTCATAAGTAAAA
AAGATGCAGTCATCTTTTTAATTGACTGCAACAAGAAGATCTTCCAAAACGAGTTTAATG
ATGAAGTAAAACTATTTTTGAAAAGTTTTGATTTTAATTGTGTTTTAAATATTTGTTTAT
TGCAGGTTTAGTTTAAAGTAATACTAAAGAGTATTTAGAGTTTCTTCAAGTCAAAGATTA
TTTCAAGTTTAGATGACTAAGTTTCTGTTATTTTCTACAATGTGGTATGATATTTCATTT
GAAAAGACTTTCAATTTTAAGGTTTATTACAAAAAATCAATCAAAGAAACAAACAAATAA
TGATTTGAACTTTAAGGGGATCAATATAGTTTATAATCTTAGCACTCCTTCAGCAGAAAT
GATTAAAAACGTAGTTAAGTTAGGTAATCTAATTGTAGGTTTTATAAAGTAATTCATATT
ACTTACATTATAATAGGAGATAATTTTGAAAGAGATTTCGGTTTTGCAGACAATGAAACA
CCTTTCCACGAAGCATTGTGGACTTGCAATAGCATTTTTACAAAATTGTAAATAATAATA
TTTAATTAAAAAATATTTGTATCTCAAGCATTTATTTATTAATTACAGAGATAGTAAAAA
ATTTATAATGAGAATATTCCTATTCACCAACAATGATTAGCCCCATTCAGATAATAAAGA
TTTTTTAGATAAGTGCTTTAACTAAGCAAGAACTTTGGCAGAAAAGAATATCTAAATTGA
GTTGTTCCCTCTTGCTACTAGAAACTAAAAGTTTGATATCAGAAAATTCTATTCAAGCAT
CATTACCTTTGATGTAGATGAAATTAATGAAGCTGTTATCGATACATCAGATAAAGTTTT
GGATATCCAACACAGATTACGTCAAAAAGAATACAAAAAAAGGTATTAATTCATATACAT
TTTTTAATTGCTAATGAATATATTTAATAGTCAGAATAATATTTAAATGATTTAAGTAAA
TAAAGTAAATAATATGATTCTAATTAATATATTTCAACTTTTATCAAATATTCACTTATC
TTGTATCAAGCAATGAATCATTAATAGCTATAAAATTATAGATTTTAATTTATTAAAACT
AAAAAGAAAGTCAATAAATTAAATGCATGTACCATGAATAACTAACTATATAATTATGGA
TTTTAATTTATTTAAACTACAACGAAAGTGAATTAATTAAATACATGCATCATGGCTGGC
TGGATATAAAATTATGGATTTCAATTTATAAAAATTTTAAAGAAAGTAAATTAATTAAAT
AATAAATAAATAAAAAAAAGGGCAGTCAACAGATTACTTTTTACTTTGGGTGATGAAACT
AGATTGGGAGTCAAATTGTTTTGCCCATTCGTGAAATAAAGACGCCCTCTTGCCAAATAA
TTAGAATCTAACACTAATAAACTTTTAAAAAGGACAGTAAAGCATATTTGCAAAGAAACA
GGTTAGTCTTTATATCAAAACCAAATTTCCACATGTGTTCACATTGGAGGAGAGAAGGTT
AAAGTTAGTAAAGGTGATATTAATGAAATCAAATCATTCGAAGAACCAGGTATGCGTTTA
ATAGGATTTAAACCTTCAGGAACACTTAAGGCTTACCACAACTATAGAACAAGCTACTTT
GTTTACCCAGATGATTATCATGTAAAGGGATCATCTCAATCTTTTCATGCTTTGATCTCA
TAAATGATTGCCAAAGATAAAATAGCTATTGTTAGATTCATTCCCCGTAAAGGCACTTAG
GTTAGGTTCTGTGCTTTACTTCCATAAGAAGAAAGTTATGATGAAGACCATGTTTAAACA
CCTCCAGGCTTTCGTAAGATTTTTTTTTTCTATGTATTTATTTAATGAATTTAAACTTAT
TAGATTTGATTTTCTTACCATATGCTGATGATTAGAGAAATTTAGGTTCCATCAGACCTT
AATAAAAGGAAGAAGTTAGCAGAAATTTACTAAATGCAGCTAAAATGATGTGCAATGCAT
TAGATTTAGCTAATTTTGATTTTAGAAATTTCGAAGATCCTTCACTATAGAAATTTTTTG
CTCATCTTCAGGCACATGCCTTATAAGAAGAAAACCCAGAAAATCCAGCAGACTTGATCT
AACCTGATGAAGAAGGTATGAAACGCTGTGAAGATATAATTAAGCTATTTGAAGAAGCAT
TGAAGTTAGATGTATAAGATGATGACCAACCTCAAGCCGCTTAAAAAAAACCAAGATAAA
AAAAGGTAGCTGTTGAAAAGTAACCTGCTGCACAAAAGAAAGTAAATCTTACTTAATTAA
TATCAAAATAATGAAAAAGTTTAAAATAATTTTAATTAAAATACGAAAAGTAACCTGCTC
CAAAAAAGCCTGCTTAAAACAAAAAATAAGTAAAAAAAGAAGAAGAGTCTGAAGCAAGCA
GTATAGGTGATTATGACTCTGAGGACTCCTTTATCGATAATGAAGAAGATGAAATTAAGC
CTAAAAAAAGAGGAGTTTAAAACAAAAAAGTGACTAATTAAAGAAAAGTTAATAAAAAAG
TTGAATACAGTGATGAAGATGATGAGATAAGCTATGAAGAAAAACCAAAACGAAAAGCAG
CAGGGAAGAAACAAATGAGCGAAGAAGAAAAACTTATTTCACATGTAGAAGCTAATTTAA
AAGAAGAATTCAACCCAGATGGTTTGACAATATCTGAGCTTAAATAGTATCTTAAGTTCA
AAGGACTTAAAAATGTTGGTAAAAAGGAAGAATTGGTTGATACCATTTTAAGACACTTAG
AAAGAAATTGA