TGD | Gene Details

Identifiers and Description

Gene Model Identifier
TTHERM_00497900

Standard Name
FLP1 (FLiPpase)

Aliases
PreTt06955 | 62.m00239 | 3715.m00100

Description
phospholipid-translocating P-type ATPase, flippase family protein

Genome Browser

Gene Ontology Annotations

Molecular Function
catalytic activity (IEA) | GO:0003824
Biological Process
metabolic process (IEA) | GO:0008152

Domains

( PF00122 ) E1-E2 ATPase
( PF06637 ) PV-1 protein (PLVAP)
( TIGR00099 ) Cof-like hydrolase
( TIGR00338 ) phosphoserine phosphatase SerB
( TIGR02886 ) anti-sigma F factor antagonist
( PF00702 ) haloacid dehalogenase-like hydrolase
( PF08282 ) haloacid dehalogenase-like hydrolase
( TIGR01524 ) magnesium-translocating P-type ATPase
( TIGR01482 ) Sucrose-phosphate phosphatase subfamily
( TIGR01525 ) heavy metal translocating P-type ATPase
( TIGR01484 ) HAD-superfamily hydrolase, subfamily IIB
( PF06686 ) Stage III sporulation protein AC
( TIGR01647 ) plasma-membrane proton-efflux P-type ATPase
( TIGR01522 ) calcium-transporting P-type ATPase, PMR1-type
( TIGR01517 ) calcium-translocating P-type ATPase, PMCA-type
( TIGR01116 ) calcium-translocating P-type ATPase, SERCA-type
( TIGR01652 ) phospholipid-translocating P-type ATPase, flippase
( TIGR01488 ) HAD-superfamily hydrolase, subfamily IB (PSPase-like)
( TIGR01494 ) ATPase, P-type (transporting), HAD superfamily,

Gene Expression Profile

Tetrahymena Functional Genomics Database: TTHERM_00497900

Homologs (v.2006 protein sequences)

Source Identifier Score Description

SGD YIL048W 9.99709313703352e-262 NEO1 SGDID:S000001310, Chr IX
from 261436-264891, Verified O
RF, "Protein involved in the r
etrograde transport from the G
olgi complex to the ER and the
endosomal membrane traffic; p
utative aminophospholipid tran
slocase; member of the highly
conserved Drs2 family of P-typ
e ATPases"

WormBase F36H2.1a 9.99709313703352e-262 WBGene00009498 tat-5 E1-E2 ATP
ase

WormBase F36H2.1b 9.99709313703352e-262 WBGene00009498 tat-5

DictyBase DDB0216656 9.99709313703352e-262 JC1V2_0_01110 P98195 Potential
phospholipid-transporting ATP
ase IIB (EC 3.6.3.1).

FlyBase FBgn0051729 9.99709313703352e-262

FlyBase FBgn0051729 9.99709313703352e-262

IPI(HUMAN) IPI:IPI00396022.2 9.99709313703352e-262 MP00000073082 Tax_Id=9606 ATP
ase, Class II, type 9B

ParameciumDB GSPATP00007622001 9.99709313703352e-262 Paramecium tetraurelia GSPATP0
0007622001 protein

ToxoDB 42.m03340 9.99709313703352e-262 Toxoplasma gondii phospholipid
-transporting ATPase, putative

WormBase F36H2.1c 9.99709313703352e-262 WBGene00009498 tat-5

TAIR AT3G27870 1.00009439685371e-101 haloacid dehalogenase-like hyd
rolase family protein

PlasmoDB PFL1125w 2.99854357435331e-72 Plasmodium falciparum PFL1125w

CryptoDB EAK90606 9.99541707625281e-72 Cryptosporidium parvum (Iowa)
protein EAK90606

Source	Identifier	Score	Description
SGD	YIL048W	9.99709313703352e-262	NEO1 SGDID:S000001310, Chr IX from 261436-264891, Verified O RF, "Protein involved in the r etrograde transport from the G olgi complex to the ER and the endosomal membrane traffic; p utative aminophospholipid tran slocase; member of the highly conserved Drs2 family of P-typ e ATPases"
WormBase	F36H2.1a	9.99709313703352e-262	WBGene00009498 tat-5 E1-E2 ATP ase
WormBase	F36H2.1b	9.99709313703352e-262	WBGene00009498 tat-5
DictyBase	DDB0216656	9.99709313703352e-262	JC1V2_0_01110 P98195 Potential phospholipid-transporting ATP ase IIB (EC 3.6.3.1).
FlyBase	FBgn0051729	9.99709313703352e-262
FlyBase	FBgn0051729	9.99709313703352e-262
IPI(HUMAN)	IPI:IPI00396022.2	9.99709313703352e-262	MP00000073082 Tax_Id=9606 ATP ase, Class II, type 9B
ParameciumDB	GSPATP00007622001	9.99709313703352e-262	Paramecium tetraurelia GSPATP0 0007622001 protein
ToxoDB	42.m03340	9.99709313703352e-262	Toxoplasma gondii phospholipid -transporting ATPase, putative
WormBase	F36H2.1c	9.99709313703352e-262	WBGene00009498 tat-5
TAIR	AT3G27870	1.00009439685371e-101	haloacid dehalogenase-like hyd rolase family protein
PlasmoDB	PFL1125w	2.99854357435331e-72	Plasmodium falciparum PFL1125w
CryptoDB	EAK90606	9.99541707625281e-72	Cryptosporidium parvum (Iowa) protein EAK90606

General Information

Paragraph No Gene Name Paragraph Text
19 FLP11,
FLP18,
FLP17,
FLP8,
FLP16,
FLP15,
FLP14,
FLP6,
FLP13,
FLP10,
FLP2,
FLP1,
FLP3,
FLP9,
FLP12,
FLP4,
FLP7,
FLP5,
FLP19 The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00497900(coding)
ATGGCTGAGGACTCAGGTGATGAGATAGAACTTTAAATGAAGGATTAGAATGATGTTAGT
GATGGGAAAAATTATTTAGAGCCTAATGGGCAAGAAGAGGATCTTTTGTTTAAAAAGAAT
AAAAATCTGTACAATTGCTTGAGTGGTAATTCTTAGCATGAAGGAGATAGAAAAATTTAC
TTAGATGGGCATTCAGTGCCTAAAATAAATGTGCAAAATGTTGTGAGAAATCAAAAATAT
AACATTTTTACTTTTATTCCTTGTGTGCTTTACAATCAATTCAAGTTTTTCTTCAACTTT
TTTTATTTATTAATATGCATTTCTCAGTTTATTCCAGCCTTAACTGTAGGGTTTCTCTTC
ACTTACATAGCTCCTTTAGCTTTTGTGCTAATTTTAACTATGATTAAAGATGCATACGAC
GATTACAAAAGATATAAAAGAGACAAAGAAGCAAATAGTTCACTTTATGAAGTTATTGTC
AACGGACAAATAAAATTAATTCCTAGTATGAACTTAAAAGTAGGATAAATCGTAAAAGTA
AATTTAAAATAAAGAATTCCTGCTGATTTAATTATACTCACTGCTTCTGAGCCAAATGGT
ACTGTTTTTATCCGTACAGACTAGCTTGATGGTGAAACAGACTGGAAAATTAGAAAATGT
ATCAGACATACACAAAACGAAGTCGACTTTTAAAATGCTGTAAGTCTTTAAAAGCTGGGA
GGTCACGTTGTCATTAACTAGCCTTAAGAAAATATCTATGAGTTTTCAGGTTTATATAAA
TTTAATGATCACTAAGAACCACTTAATTTAGAAAACACTCTCTGGTGCAACACAATTTTA
GCATCTGGACATATATGGGGTTTGGTCATACACACAGGAAAGGAAACAAGAATGGCTATG
AATTCAAGGCATCCTAGAAGCAAATTTGGGCTCTTTGATGAAGAAGTCAACTAGCTATCA
AAAATATTATTTTACTTTATGATTATCCTTTCATTTGTAATGATACTTTTCCATGGATTC
ACATCTCTATGGGTAATTTAGTATTTCCGTTACCTACTTTTGCTAAGTAGCATCATACCC
ATTTCCTTAAGAGTTAACAATGACTTTGCAAAAGCAGTATTCTCCTATTAAATTCAAAAC
GATAAGTCTATTGAAGGTACAGTCGCAAGAAACTCTAATATACCAGAAGAATTAGGAAGA
ATATAATACGTTTTGGCAGATAAAACAGGAACTCTCACACAAAACGATATGATATTTAAA
AAGATTATTATCAGTGAGAAATAATATACAGAAGAAGACTTCAATGAAATTAGATCCATT
CTTTCCAAACATTGCCAAAAACACAAAGGTCCACTTTCTGATGTAGAAGGTGATACAATT
GCAGAAAATAAAAGGCATTTGCGCAGAAAAAATGATTATTTACTTAGAGATGCAATCACA
GCACTAGCAGTCTGCCACAACGTTACTCCAGTTATTGAAGACGGAGAAACCGTTCTTTAA
GCATCAAGTCCTGATGAGCATGCACTTGTGAAATTCGCACAAAGCTTAAATATAACTCTG
CTTTCAAGAGATGAGCAAAAAGTAGTTGTAAGAAATGCTGCTAAAGAAGAAGAGCACTTT
GAAATTCTTGCTTGCTTTCCCTTCAGCTCCGAAACCAAAAGAATGGGTATACTTGTTAGA
CACTAAAAGACCAATAAAATTATATACTACTTGAAAGGTGCTGATGCTATCATGGTAACG
AGAGTAAGAAAAGTTTACCATCCACTTATCAATGATGACTGTGACAATCTAGCTAGAGAA
GGTCTTCGTACTCTTGTTGTTGCACAAAAGCTGATTTCAGAAGAGTTTTACAAGGATTGG
AGAGCCAAGTACAATAAAGCATAAGAACACATGCAAAATAGAAATGCAAAAATTAGAGAA
GTTGCTGAGTTATTAGAAGTAGATATGGAGCTTTTAGCTGTTACAGGTGTAGAAGATAAA
CTTCAAGATGAAGTCTGCTCTACAATTGAAAGTATGAGGTAAGGTGGGATAAAAGTGTGG
ATGCTTACAGGAGATAAAGTAGAAACAGCTAAATGTATAGCAATCAGTGCAGGTTTGTAA
TCAAGAAATTAAGAAATATTTGAAATCAAAGATGAAACAGATGAAATGGCTATAAGAGAA
CTGATTAATAAATTTTCTCATAAATCTGATTGTGTTTTACTAATTGATGGTGTATCACTG
ACTAGAGTAATATAATCTTGCTCAAAAATTTTCTTTGAAACTGCTTGCCAAGCTCCAGCT
GTAATTTGTTGTAGATGTGCACCCAAATAAAAGGCTGAAGTTACAGAGATGCTTAAAAAA
TACTCCAAAAAAAGAGTACTTTGTATTGGTGATGGTGGTAATGATGTCGGTATGATATAA
TGTGCTCATGTAGGAGTAGGTATTGTAGGAAAAGAAGGAAAACAAGCTGCTTTAGCCTCT
GATTTTTCAATTTTAGAATTCAAACACATCAAGTAGTTATTATTTTGGCATGGTAGAAAC
TCATATAAAAAAGCAACCACATTAAGTTTGTTTGTCATCCATAGAGGTTTAATTATAAGT
ATTATCTAATTTGTTTTCAGTAGTGTCTTCTATTTTGTAGCCATTCCTATTTACAATGGT
ATGCTGATGCTTGGTTATTCAACTTTTTATACATCTTTACCTGTCTTCTGTTTGATTTTT
GACTAAGATATTTCTTAAAAAATGGTTCAACATATGGATCTGGATTAGCATTTACTAAGG
AGCTTTAATCATGCTTATGACTTTAACTATGTTTAAAGAAGCCTTTTTAAATATTGTGAC
CATTACATTTACGTCATTAATTTTTATTGA

>TTHERM_00497900(protein)
MAEDSGDEIELQMKDQNDVSDGKNYLEPNGQEEDLLFKKNKNLYNCLSGNSQHEGDRKIY
LDGHSVPKINVQNVVRNQKYNIFTFIPCVLYNQFKFFFNFFYLLICISQFIPALTVGFLF
TYIAPLAFVLILTMIKDAYDDYKRYKRDKEANSSLYEVIVNGQIKLIPSMNLKVGQIVKV
NLKQRIPADLIILTASEPNGTVFIRTDQLDGETDWKIRKCIRHTQNEVDFQNAVSLQKLG
GHVVINQPQENIYEFSGLYKFNDHQEPLNLENTLWCNTILASGHIWGLVIHTGKETRMAM
NSRHPRSKFGLFDEEVNQLSKILFYFMIILSFVMILFHGFTSLWVIQYFRYLLLLSSIIP
ISLRVNNDFAKAVFSYQIQNDKSIEGTVARNSNIPEELGRIQYVLADKTGTLTQNDMIFK
KIIISEKQYTEEDFNEIRSILSKHCQKHKGPLSDVEGDTIAENKRHLRRKNDYLLRDAIT
ALAVCHNVTPVIEDGETVLQASSPDEHALVKFAQSLNITLLSRDEQKVVVRNAAKEEEHF
EILACFPFSSETKRMGILVRHQKTNKIIYYLKGADAIMVTRVRKVYHPLINDDCDNLARE
GLRTLVVAQKLISEEFYKDWRAKYNKAQEHMQNRNAKIREVAELLEVDMELLAVTGVEDK
LQDEVCSTIESMRQGGIKVWMLTGDKVETAKCIAISAGLQSRNQEIFEIKDETDEMAIRE
LINKFSHKSDCVLLIDGVSLTRVIQSCSKIFFETACQAPAVICCRCAPKQKAEVTEMLKK
YSKKRVLCIGDGGNDVGMIQCAHVGVGIVGKEGKQAALASDFSILEFKHIKQLLFWHGRN
SYKKATTLSLFVIHRGLIISIIQFVFSSVFYFVAIPIYNGMLMLGYSTFYTSLPVFCLIF
DQDISQKMVQHMDLDQHLLRSFNHAYDFNYVQRSLFKYCDHYIYVINFY

>TTHERM_00497900(gene)
ATGGCTGAGGACTCAGGTGATGAGATAGAACTTTAAATGAAGGATTAGAATGATGTTAGT
GATGGGAAAAATTATTTAGAGCCTAATGGGCAAGAAGAGGATCTTTTGTTTAAAAAGAAT
AAAAATGTAGAAATTAAATTCTTATATTTTAAAAGCGAATCCAATAGAATGAAAGTGATT
AAAGCATTTAAATTTAACAGTTTTTCTAAGTAGAAAAGCAAAAATAAAACATTTTTTTAT
TTGAAATTTGGAAACAAAGCCATATTTATTTATTTAGAACTAAAATATATTTGTAATATT
AGATTTATGAAAATATTTATCATTAATTTTAATAGAAAAAGAAATCAGTTAGTTTTTTTT
CCAAGCTGTACAATTGCTTGAGTGGTAATTCTTAGCATGAAGGAGATAGAAAAATTTACT
TAGATGGGCATTCAGTGCCTAAAATAAATGTGCAAAATGTTGTGAGAAATCAAAAATATA
ACATTTTTACTTTTATTCCTTGTGTGCTTTACAATCAATTCAAGTTTTTCTTCAACTTTT
TTTATTTATTAATATGCATTTCTCAGTTTATTCCAGCCTTAACTGTAGGTAAATAGAGTT
CATTTAATTATTTGAAATGTCTTTTGAGAAATAAATATTAGCCCTAATTGTATTTTGAGA
ATATAGATGGTAAAAACTATTTTTTTTAATTTATAGGGTTTCTCTTCACTTACATAGCTC
CTTTAGCTTTTGTGCTAATTTTAACTATGATTAAAGATGCATACGACGATTACAAAAGAT
ATAAAAGAGACAAAGAAGCAAATAGTTCACTTTATGAAGTTATTGTCAACGGACAAATAA
AATTAATTCCTAGTATGAACTTAAAAGTAGGATAAATCGTAAAAGTAAATTTAAAATAAA
GAATTCCTGCTGATTTAATTATACTCACTGCTTCTGAGCCAAATGGTACTGTTTTTATCC
GTACAGACTAGCTTGATGGTGAAACAGACTGGAAAATTAGAAAATGTATCAGACATACAC
AAAGTAAAAATAGTTTAAAATAAACTATTACGTTTATTATTACAATTTTTTGTTACTTTG
AATATTTTTGTGATTTACGAGAAATAAATAAATAAAAAAATAAATAGACTGGTTTCGTAA
TTTACTGATAAATTAAGGTTGTGTTGTAATTCAAAAATTTTAATGTTATTGAGTAACTAA
ATTTTCATAAATAATTTGTCTATTAGATATGCTTTTTATTTAAATTTAACAAGAACCAGC
TTTTATCAATAATTTTACTTTTTTATTCTTACTATAACTATTTTAAATTAATAGACGAAG
TCGACTTTTAAAATGCTGTAAGTCTTTAAAAGCTGGGAGGTCACGTTGTCATTAACTAGC
CTTAAGAAAATATCTATGAGTTTTCAGGTTTATATAAATTTAATGATCACTAAGAACCAC
TTAATTTAGAAAACACTCTCTGGTGCAACACAATTTTAGCATCTGGACATATATGGGGTT
TGGTCATACACACAGGAAAGGAAACAAGAATGGCTATGAATTCAAGGCATCCTAGAAGCA
AATTTGGGCTCTTTGATGAAGAAGTCAACTAGCTATCAAAAATATTATTTTACTTTATGA
TTATCCTTTCATTTGTAATGATACTTTTCCATGGATTCACATCTCTATGGGTAATTTAGT
ATTTCCGTTACCTACTTTTGCTAAGTAGCATCATACCCATTTCCTTAAGAGTTAACAATG
ACTTTGCAAAAGCAGTATTCTCCTATTAAATTCAAAACGATAAGTCTATTGAAGGTACAG
TCGCAAGAAACTCTAATATACCAGAAGAATTAGGAAGAATATAATACGTTTTGGCAGATA
AAACAGGAACTCTCACACAAAACGATATGATATTTAAAAAGATTATTATCAGTGAGAAAT
AATATACAGAAGAAGACTTCAATGAAATTAGATCCATTCTTTCCAAACATTGCCAAAAAC
ACAAAGGTCCACTTTCTGATGTAGAAGGTGATACAATTGCAGAAAATAAAAGGCATTTGC
GCAGAAAAAATGATTATTTACTTAGAGATGCAATCACAGCACTAGCAGTCTGCCACAACG
TTACTCCAGTTATTGAAGACGGAGAAACCGTTCTTTAAGTAAACATACTTTTTTTCTCAA
ATTTAATTATTTAGCAAATAATAAATAATAAAGGCATCAAGTCCTGATGAGCATGCACTT
GTGAAATTCGCACAAAGCTTAAATATAACTCTGCTTTCAAGAGATGAGCAAAAAGTAGTT
GTAAGAAATGCTGCTAAAGAAGAAGAGCACTTTGAAATTCTTGCTTGCTTTCCCTTCAGC
TCCGAAACCAAAAGAATGGGTATACTTGTTAGACACTAAAAGACCAATAAAATTATATAC
TACTTGAAAGGTGCTGATGCTATCATGGTAACGAGAGTAAGAAAAGTTTACCATCCACTT
ATCAATGATGACTGTGACAATCTAGCTAGAGAAGGTCTTCGTACTCTTGTTGTTGCACAA
AAGCTGATTTCAGAAGAGTTTTACAAGGATTGGAGAGCCAAGTACAATAAAGCATAAGAA
CACATGCAAAATAGAAATGCAAAAATTAGAGAAGTTGCTGAGTTATTAGAAGTAGATATG
GAGCTTTTAGGTAATTATTAATATCTATTTGTATATTAAGTAAATTAAAATAAATTAATA
ATTTTAATAGCTGTTACAGGTGTAGAAGATAAACTTCAAGATGAAGTCTGCTCTACAATT
GAAAGTATGAGGTAAGGTGGGATAAAAGTGTGGATGCTTACAGGAGATAAAGTAGAAACA
GCTAAATGTATAGCAATCAGTGCAGGTTTGTAATCAAGAAATTAAGAAATATTTGAAATC
AAAGATGAAACAGATGAAATGGCTATAAGAGAACTGATTAATAAATTTTCTCATAAATCT
GATTGTGTTTTACTAATTGATGGTGTATCACTGACTAGAGTAATATAATCTTGCTCAAAA
ATTTTCTTTGAAACTGCTTGCCAAGCTCCAGCTGTAATTTGTTGTAGATGTGCACCCAAA
TAAAAGGCTGAAGTTACAGAGATGCTTAAAAAATACTCCAAAAAAAGAGTACTTTGTATT
GGTGATGGTGGTAATGATGTCGGTATGATATAATGTGCTCATGTAGGAGTAGGTATTGTA
GGAAAAGAAGGAAAACAAGCTGCTTTAGCCTCTGATTTTTCAATTTTAGAATTCAAACAC
ATCAAGTAGTTATTATTTTGGCATGGTAGAAACTCATATAAAAAAGGTAAATAAACATTT
TTTTAATTACTATGATTTAAATCTACCTAAAAAATAATTAAGATAAATATTGATTCTAAA
AGAAAATTTAAATGTTAAATTTTAAAGAATAAAATTTTATTTCAGCATTTTAAGTTTGCT
GTTCAGCATCTTAAAATTTATTAATGATTTTGAAAAAAAATCTATTTATAAAATTACATT
TTTATAAGACAATTAACAAATTATTGAAATTAAGAATTAATTTTGAACAAAAATATAACA
AAGATTTTAAATTTAATTTTCTAAATTCTAAAATTTAAATAAATTTAATATTTTACTATA
AAGCAACCACATTAAGTTTGTTTGTCATCCATAGAGGTTTAATTATAAGTATTATCTAAT
TTGTTTTCAGTAGTGTCTTCTATTTTGTAGCCATTCCTATTTACAATGGTATGCTGATGC
TTGGTTATTCAACTTTTTATACATCTTTACCTGTCTTCTGTTTGATTTTTGACTAAGATA
TTTCTTAAAAAATGGTTCAACAGTACCCTTAATTATATAAAACTCTATAAAGAAACAAAA
GAATGAGCACAAAATCAATATTAGTATGGATCTGGATTAGCATTTACTAAGTAATTAAGT
TAATCAAATTATATTTATCTAATAATTTTTACTACTAACAGGGAGCTTTAATCATGCTTA
TGACTTTAACTATGTTTAAAGAAGCCTTTTTAAATATTGTGACCATTACATTTACGTCAT
TAATTTTTATTGA

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Identifiers and Description

Gene Model Identifier

Standard Name

Aliases

Description

Genome Browser

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

Gene Expression Profile

Homologs (v.2006 protein sequences)

General Information

Associated Literature

Sequences

Wiki Links

External Links

Paragraph No	Gene Name	Paragraph Text
19	FLP11, FLP18, FLP17, FLP8, FLP16, FLP15, FLP14, FLP6, FLP13, FLP10, FLP2, FLP1, FLP3, FLP9, FLP12, FLP4, FLP7, FLP5, FLP19	The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).