Identifiers and Description

Gene Model Identifier

TTHERM_00377310

Standard Name

None

Aliases

PreTt10284 | 40.m00169

Description

calcium/calmodulin-dependent kinase; Protein kinase domain containing protein. Sequence similarity to the CAMK1 protein kinase family (Eisen et al.- 2006).

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00377310

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_00130.1	9.997093137033517e-262	protein kinase domain-containi ng protein (312 aa)
Oxytricha	Contig1389.1.g59	1.999149254372995e-126	Protein kinase domain
DictyBase	DDB_G0279925	6.002904662242373e-91	mlkA on chromosome: 3 position 2752719 to 2754560
WormBase	WBGene00000553	5.000624069301489e-83	locus:cmk-1 Calcium/calmodul in-dependent protein kinase ty pe 1 status:Confirmed UniP rot:Q9TXJ0 protein_id:CCD718 65.1
SGD	YOL016C	8.003355238965419e-63	CMK2 Calmodulin-dependent prot ein kinase; may play a role in stress response, many CA++/ca lmodulan dependent phosphoryla tion substrates demonstrated i n vitro, amino acid sequence s imilar to Cmk1p and mammalian Cam Kinase II
Stentor Coeruleus	SteCoe_33528	3.093350011308561e-50

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00377310(coding)
ATGGAAGACGAAAGCCCTGCCATCGAAGATGTCTACACTTTCGATAAAGTATTAGGAGAA
GGATCTTTCGGTATTGTCAAGAGAGCCATTAAAAAGGATACCGGTGAAGCTTTTGCAGTT
AAAATGATCAAAAAGGAAAATCTCGAAAGCGATGATATGAATGCTTTACAGTAAGAAGTC
GAAATATTAACTGAAATTGATCATCCAAATGTAGTAAAACTATATGAAATATATGAAGAT
GATGCTTATTTTTACATGGTTTTAGAGCTTATGACTGGAGGAGAATTATTCTAGCGTATT
GTGGAAGCAGATCACTTCTCTGAAAGATAAGCAGCCGAAACTATTAAGCCTGTAGTAGAT
GCCTTGCATTATTGCCATGCCCTAAATATTGCTCATAGAGATTTAAAACCTGAAAATTTA
CTTTATGCCACTAAAGAACCAGGTGCAGTTATCAAAATTTCAGATTTCGGTCTTGCTAGA
TTTGTAGGAGAAAATACAATGACTACTATGTGTGGTACTCCAGGTTACGTAGCACCTGAT
ATTATTCTTGGATAAGGTTATGATAAGACTATTGATTATTGGAGCGTTGGAGTTATTCTT
TACATCATGCTATGTGGTTTCCCTCCTTTTTATAGTGAAAATAATGATGAACTTTTTGAG
TTGATTGTTAAGGGTAAGTTTGAATTCCCTTCACCAGCATGGGATTCTATTTCAAATGAA
GCTAAGGATTTAATCAAGGGATTACTTACAGTTGATCCTAAAAAGAGATTTAATTATGAA
AAAATTAGTGCTCATCCCTGGTTGAATGGAAAGAGCTCTGACACAAGTATTCCTGATATT
CAAAAAAAGATTAAAAATTTTTCAGCTTCCAAATAGTTCAAGAAAATTAAAATAGTTTTA
TAAGCTGTTAGCAAACTCAATAAAAACTAAAAAAGTCATTGA

>TTHERM_00377310(protein)
MEDESPAIEDVYTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESDDMNALQQEV
EILTEIDHPNVVKLYEIYEDDAYFYMVLELMTGGELFQRIVEADHFSERQAAETIKPVVD
ALHYCHALNIAHRDLKPENLLYATKEPGAVIKISDFGLARFVGENTMTTMCGTPGYVAPD
IILGQGYDKTIDYWSVGVILYIMLCGFPPFYSENNDELFELIVKGKFEFPSPAWDSISNE
AKDLIKGLLTVDPKKRFNYEKISAHPWLNGKSSDTSIPDIQKKIKNFSASKQFKKIKIVL
QAVSKLNKNQKSH

>TTHERM_00377310(gene)
ATGGAAGACGAAAGCCCTGCCATCGAAGATGTCTACACTTTCGATAAAGTATTAGGAGAG
TAAAAAAAAATTAATTCAAATGATTTTCAAGCATGATATTGTCATATTCTGAATTATTTT
ATCATTTATTGGCATAATCTGTCAATCTGTCTATCCTGCAAATAAGCTCAAATATAATTA
ACAATTACAAACATGCTTAATAGATCAAACTTACAATTTTATTAAATTTTGGCTTAATTT
CTTTTTAAAAAAAGAGGATCTTTCGGTATTGTCAAGAGAGCCATTAAAAAGGATACCGGT
GAAGCTTTTGCAGTTAAAATGATCAAAAAGTATATATACTTTTAACTAGTTTTATTTCAA
AGTTACTATGCACACATACTTACTTACTTAAATAAATCAAATTGGTTTGTCTGCATATGA
AATATTCATATTTTTATTCGCAGCAATTCGACTAACTTAAATTATTTTAAAAGGGAAAAT
CTCGAAAGCGATGATATGAATGCTTTACAGTAAGAAGTCGAAATATTAACTGAAGTAATT
TTTTAAACAATCAATTTATCTGTTTTTAAATATTTTACATAATTATTCAGATTGATCATC
CAAATGTAGTAAAACTATATGAAATATATGAAGATGATGCTTATTTTTACATGGTTTTAG
AGCTTATGACTGGAGGAGAAGTAATTAATTATTATGATTAAATTAGATAGATCGCTTAAA
TAAATGACAATTATTTGCATTTCAAAATTATTTTGCAACATGATTTTTTATTAACTAAAC
CAAAAAGTTATTCTAGCGTATTGTGGAAGCAGATCACTTCTCTGAAAGATAAGCAGCCGA
AACTATTAAGCCTGTAGTAGATGCCTTGCATTATTGCCATGCCCTAAATATTGCTCATAG
AGATTTAAAAGTAAGACTTAACAATTTAAAAGTGCATAAAAAATAAATAATTTTATCTAA
TAACTTAAATCAAAAAGCCTGAAAATTTACTTTATGCCACTAAAGAACCAGGTGCAGTTA
TCAAAATTTCAGATTTCGGTCTTGCTAGATTTGTAGGAGAAAATACAATGACTACTATGT
GTGGTACTCCAGGTTACGTAGCACCTGATATTATTCTTGGATAAGGTTATGATAAGACTA
TTGATTATTGGAGCGTTGGAGTTATTCTTTACATCATGTAATTACTTACTTACTTAATTT
ATATTAATGTTTTAAATATTTTGTAAACAAAATGTTAAATAGGCTATGTGGTTTCCCTCC
TTTTTATAGTGAAAATAATGATGAACTTTTTGAGTTGATTGTTAAGGGTAAGTTTGAATT
CCCTTCACCAGCATGGGATTCTATTTCAAATGAAGGTAAAATAGAATTTTATTAATTTTG
TGGTTACTCTTTTTTTTTCAATAAAAATCTATTTAATAAATAAATAGCTAAGGATTTAAT
CAAGGGATTACTTACAGTTGATCCTAAAAAGAGATTTAATTATGAAAAAATTAGTGCTCA
TCCCTGGTTGAATGGAAAGAGCTCTGACACAAGTATTCCTGATATTCAAAAAAAGATTAA
AAATTTTTCAGCTTCCAAATAGTTCAAGGTAGATTCTTTCTGATTGATTTTGAATGAATT
TAAGAAAAATAATAATTTATTTATATTATAAAAATAGAAAATTAAAATAGTTTTATAAGC
TGTTAGCAAACTCAATAAAAACTAAAAAAGTCATTGA