Identifiers and Description

Gene Model Identifier

TTHERM_00194050

Standard Name

MYO4 (MYOsin )

Aliases

PreTt06689 | 16.m00345

Description

MYO4 myosin head protein; Myosin heavy chain; member of proposed myosin Class XX- distinct from previously defined myosin classes; contains predicted coiled-coil and myosin tail homology (MyTH4) domains

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Cellular Component

Molecular Function

Domains

  • ( PF00784 ) MyTH4 domain
  • ( TIGR01612 ) rhoptry protein
  • ( PF08736 ) FERM adjacent (FA)
  • ( TIGR00166 ) ribosomal protein S6
  • ( PF00063 ) Myosin head (motor domain)
  • ( PF05316 ) Mitochondrial ribosomal protein (VAR1)
  • ( PF09124 ) T4 recombination endonuclease VII, dimerisation

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12.1%

TetraMine Data

TTHERM_00194050

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_03677.19.997093137033517e-262myosin (2110 aa)
OxytrichaContig18292.0.g1085.998752501907352e-124Myosin head (motor domain)
DictyBaseDDB_G02886796.002710752508619e-120myoE on chromosome: 5 position
1829072 to 1832587
WormBaseWBGene000020391.0001155149984988e-113locus:hum-6 Unconventional m
yosin heavy chain 6 status:P
artially_confirmed UniProt:P
91443 protein_id:CCD61190.1
SGDYHR023W9.004095103885247e-102MYO1 Type II myosin heavy chai
n, required for wild-type cyto
kinesis and cell separation; l
ocalizes to the actomyosin rin
g; binds to myosin light chain
s Mlc1p and Mlc2p through its
IQ1 and IQ2 motifs respectivel
y

General Information

Paragraph NoGene NameParagraph Text
10MYO1,
MYO12,
MYO11,
MYO10,
MYO9,
MYO4 ,
MYO5,
MYO4,
MYO3,
MYO2,
MYO13
Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

  1. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
  2. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43

Sequences

>TTHERM_00194050(coding)
ATGCTAGATATAAATACTACATGGATGATTCCGGACAGTGAGTGCTGGATTTAAGTAGGA
GAAGAAGATGCATAAACATAAACAATGTTTGTGAAAGCTAAAATAAAATAAAAACCCAGT
CTTTCAAACATTAATAAGAATAATGTTTAACAATGTTTTGCTGACATAAAAGATGTAGAA
GATAATCGATATGCTAATATAACAAAAGTTAAAATAAATTCAGTTTATTAAGTAAACTAA
GAAGTACCTTAAGGTTATAATGATATGGTAGAAATGGATCACTTGAATTAAGCAGAAATT
CTTATTAATTTATAAAGAAGATACGATTAAGATTTAATATTTACATTTATAGGTCCTACA
CTTGTAGTGATGAATCCTTACAAGTTAATTCCAAAGCATTTTTCAAATGAAACTCGTAAT
ATTTTTTCATAATAAGCAAAACACCAAGGCTACATCGATTATAAAAAAAATGATCCACAT
ACTTATGCTGTAGCTGCTTAATCATATTGTAAGCTTTTTGAGTAAAATAAAAATCAAGCC
ATAGTAATATCAGGTGAGTCAGGTGCAGGAAAGACTGAAAATGCCAAAATATGCATGTGT
TTTCTTACAGGATTAAGCGGATAAGATGCTGAAAGAAGACCTAGTATATAAAATAGTACT
TCTCCAGCTAATAAAAATAAAAATAATATTGAAGATAGAATTTTGGGATGCAACCCTATA
TTAGAGGCGTTTGGAAATGCAAAAACTGTTAGAAATGATAACAGCTCTCGTTTTGGAAAA
TTTGTATCGATTTAAGTAGGGAAAAAATCAAGAAAAATTAAAGGTGCTACAATTTAGAAC
TATTTACTAGAAAAGAGTCGTGTTACCACTCCTGGTCCTGGAGAGCGCGGTTACCACATA
TTTTATCACTTACTCTACTGCGGATAAAACTAACTTTTAGAAAATTTATAATTGGTAGGT
TAATATTCAAAACCACAAAATCTAAATTACTTAAAAGTTAGTAATTGTTATGAAGTATCA
ACTATAAATGACAATGCTCTGTTTAAAGAAGTTGTTGAGGCCTTTCATACTATGGGTATT
AATTAAGAAGAATAGGATACTATTTTTAGGATTATAAGTTCAATCCTATTGTTGGGTAAT
GTCTAATTTGACTAATCCACTTTAACTGACACACAACCATGTACTGTTAAGGATGAAAAG
CTTCTCAAAACAATTTCAGATCTGTTAAAGCTGGATTTTTCATCTCTCTTGAGAACAATT
AACACTGTTACAAGAAAAATAGGATCCTCTGTAATATATTCACCCAAAAAAATAGATGAA
GTAATTTCCTCAAGGGATTCTATTGCTCGTAATATGTATGATAGAATGTTTTCGTGGATA
GTTACTCGTTTGAATAATTCAATTAATATAAAAGGAGAAAATGGCAAAGAAAATGAAAAT
GAAGCTTAACTCTGCATAGGTTTACTTGATATTTTTGGCTTCGAGGTATTCGAAGAAAAC
TCTTTTGAGTAATTCTGTATTAATTATACCAACGAAAAACTATAATAATTGTACATACAA
TACGTATTTAAATCTGAAGAATAGGAATTTATTATTGAAGGACTAGAAAAATACATAAAT
TAACTAGGGTACAAAGATAATTAAAATATCATTGAAGTACTTGATAATCATCCTATTGGT
ATATTTTAGCTTATCGATGAGTCGTCAGCTCTCGCACAGTCTGATGATAAAAAGCTATAT
GAAAGCATCTATAGAATAAATAATGGAAAACCTGAAGTGAAGTTTGTAAATAAAGGAAAT
AAAAAAATTTTTTAGATTGTCCACACAGCAAAACCTGTAGATTATTCAATAGAAGGATTT
AGAGATAAAAATAAAGCTGAAATAAGCTAAGAGCTTTAGTTGACTATAGCTTAAAGTGAT
GATCCTATAGTTTCCTCAATATTTTTAGGAATTTAGGATATCAAAACTAGTAAGAATGAT
AAAATTGCAGCCATTAATTAGTAGTAGTATTAGACTAAAAGTACAAAGGAGAACAAATTT
TTAGGAAGTAAGTTTAGAGCCTAAATGAAGTAGCTCATGGATGAATTAATCTAATCAGAC
TGCCATTTTATAAGATGTATAAAACCAAATGAGACAAAAAGAGCAAATAATTTGATTCAA
GGATATGTATTGATTCAAATAAAATATTTAGGAGTTTTGTAAGCCATTTTAGCTAGAAAA
GAAGGATTTCCTTATAGAAAAGACTTCAAAGTACTATTTTAGCAATTTAGTGGCATGATT
GAAAAGTATAGAACTTTAAGCCTTTAAAAGATTGAGAGCCAGAATTTGGATTTAAAAAAT
ATATCCCAAGATATCCTCTAAGAGCTTTTCAAGAATAATAAAGATGTTTTAAAACATGTT
TTAGTTGGAAAAACAAAAATATTTGCAAAGGATGATTTTGGTAAAATCTTAGATGAGATG
CTGTTTAAATGGTATGAATAGAAGAAATCATTAATATTCAAAATAATTAAACAATTTTAA
GTTTACTAATTTAAAAAAAATCTAAAAGCTAATATGAAAATTCTAATGAAAGCTATCAAA
ACTTTTCAAAAAATTTCTGCTGTATTTAAAATGAAATGTCAAAGAAAGAGATTTTTACAA
GTTAAAAAATCAACAGCATTAATTTATAGCTTAATGTGTAAGAACTTTAAAAAACAATTT
ATAAAATAGTGGAATATTAAAACAAAATAAATTATAGTCGCATAAAAATAGAAAGAAAGA
GAATAAGCTGAATTATTAGCAAAATAAAAGCTGGAAGTAAAATAATAATAAAATGAGATG
AATAAAGATGAAATAGATCAATAAATTGATTAAAATTCTATTTTATGTAACACAATAGAT
AGAAAAGATAACTACAATACAAATTTATCATAAGAGTATGCTACTATAAGTAATTACAAT
ACATTTAATGCTGTCAACAATAACTAGAATAATATAGAAATGAAGCAAAACTATAAAGAT
TTGTAAGAAAATTACTTATCATCAAAAGGAGAAGCTGACATGAATGAGAAGATGAAATAA
GAATTTGAATAAATTTAGTAAAAGAACAAGGAAATTCTTTAAGATGCCCAATTAGAAGAT
GGACTGCCTTAAAAAATAAAGTTGAAATCAAAGGTCGAATCATTTTTAAATTTAGATAAT
CCTAATATGATCCGCCCAGGTCCTAATGAAAAGAGCAAAGATTGCTTAATTGATTTCAAT
GAATGCAATCAAGAAATGATCTAAAAAATTGAATAAAGTAATTATTTTGAAATAATTAGT
ACTATTGTGGTTATTAGAAAATATAATTCTACTGATCAAAATCCATTACAAAAAATGCTT
TCTTATTAAAAGAGGCAATTAAAAAAACCTCTCACAAGTATCGATAAGCATTATGAACCT
ATAGCAACGAAAGCTTTTTCTTATATGTTAAAATATGCTGGAGATAAACCTTGCGAAGAA
ATTCATCCCAGAATCATTGCTTGGAAGCTTGCTCAACTAATTCTTGATTAGGATGTACAA
GAAGTTACTGATGAAATATTCTTGTAGGTTATAAAATAGCTAACTAATAATTCAGAAGAA
AACATAGAGTAATATTTTAAAATTGCAGCTTTGATAGCTAGTTGCGTTGTTTTATCTTGT
CGCATAGTATTTCCATCAATGAATTTTTTCTTGGAATAAGCAAGGCATTATGAAAAAAGT
GGTAAAGAGAAATTGATGGAATGGTGCAAATTTATATTGTCCAGGATCGGAAATAGCTAT
AACTTTGATGAAAATATGTAATTTCCATGCTATATATTTAAAAGAGAAGAGATGCCATTA
AAAGAAGAGTTTATTGCCTTAGAGAATATGTTTTCTATTCAAATTCCAATTCACTTTTAT
GGAGACCGCTAAAAATACTTTAAGGTAGAATCATATACCAAAATTTGTAACATGGTGAGC
CAAATTGGCTTAGATTTAGAAATTCTTTATGATAAAAACAGTTATGGATTAGTCGAATAC
ATAACTGTTGATGCAGTTACTAAAGTTTAAATTTTAGATTTTGGAATGAGAATACTTGAT
TGGAAAGCCAAGAGGTATCGTGATAGATAACAATATTTACAAAAAAATCCAGGTAAGACT
TTTGAAATAAAACTATATTACCAATGTATCATTTTTCACAGCCCAAAATCTTAAAATATT
GACACTAATCTTATGACATATCTAACATATGTAAACGAGTATTTGCATGGATTGTATTTC
TTTGATTTTAACACAAACAAAGATTAAATATAAAATAAATTAATTGACTACCCAAAAGAA
ATTACAGAAATTGATTTTATTGTTGAGATGTCTGCAGCTAAGGTGCTAGCTGATTATAAA
ATCTATAAAAAGGAAAATATTATCTTACAAAATTGCATCCCAAATTCAAAAATTATTTTC
ATAAGACATGAAGTGTGGAAGGTCAAAATCGAAGATTAAATATGTAAGTTATAACAAATT
ATAAAAACTTAAAGACAAGCAAGGACTTATTTCTTGAATAGGATGAAAGAGTACTAAGGG
AAGTACTACTTTTCTTAAAAATTTTTCTGTAAATTTAGTTAGCACCCAAACTTTTTAGAA
TAAAAGGAAGCTATTTGCTTGACTAAATTAGGCTATGTGTACATTATTGAATAGCAAACA
TACAAGTAATTGTTAGAAATTTCTTATAGAGATATAAAAGATTTTAGCATTAATTTTTAT
TCCTAATCACTTGTTTTGTATACAGAATAAAATATTTATCAAATATTTTCTTAGTATGCT
TTGAATATATACTACAACATTAAATCGTATTGCTAAACTCTTGAAGAATTAGATAATGAT
AATATCTAAGAAGATAGAAATTGCTTTTAAACTAATGAAAATTTGCTAAATAATTCAAAT
GAAAAAACTGTTTATGATTCGAAAAATTCTAATCAAGATCAAAAATCAGATAATTCATAA
GTACCAATAAATATGATTGATAAAGTTAACGATGATACTATTGTAATCGAAATGCAATAA
TACTCATCTAATGATTGTAAAAAATAATAATCACAAAAGACTTAAAAAAATGTGAGAAAT
GGAAATTTAATCACTCCTGTTAAAAATTAAAGCACATACTAAAATGAACCTTAAATACCA
AATTATTCAGCTAATATTAATAGAGGAAGTGAAGAATATTTTGATAACTCTCCTAACTCA
TAATATTCAAGTGGCCAAAATAAATTAATTAATAACATTTAAAAGAATGATTAAAAATTA
TTTTAAGAATCAAAGATAAATCTAAATAAATAGTTACAAGAAGCTTAAAATGACACAAGT
AATATAGACCAAACTAACAGGTCATGCAATTTATATGAAAATCTGCTATGA


>TTHERM_00194050(protein)
MLDINTTWMIPDSECWIQVGEEDAQTQTMFVKAKIKQKPSLSNINKNNVQQCFADIKDVE
DNRYANITKVKINSVYQVNQEVPQGYNDMVEMDHLNQAEILINLQRRYDQDLIFTFIGPT
LVVMNPYKLIPKHFSNETRNIFSQQAKHQGYIDYKKNDPHTYAVAAQSYCKLFEQNKNQA
IVISGESGAGKTENAKICMCFLTGLSGQDAERRPSIQNSTSPANKNKNNIEDRILGCNPI
LEAFGNAKTVRNDNSSRFGKFVSIQVGKKSRKIKGATIQNYLLEKSRVTTPGPGERGYHI
FYHLLYCGQNQLLENLQLVGQYSKPQNLNYLKVSNCYEVSTINDNALFKEVVEAFHTMGI
NQEEQDTIFRIISSILLLGNVQFDQSTLTDTQPCTVKDEKLLKTISDLLKLDFSSLLRTI
NTVTRKIGSSVIYSPKKIDEVISSRDSIARNMYDRMFSWIVTRLNNSINIKGENGKENEN
EAQLCIGLLDIFGFEVFEENSFEQFCINYTNEKLQQLYIQYVFKSEEQEFIIEGLEKYIN
QLGYKDNQNIIEVLDNHPIGIFQLIDESSALAQSDDKKLYESIYRINNGKPEVKFVNKGN
KKIFQIVHTAKPVDYSIEGFRDKNKAEISQELQLTIAQSDDPIVSSIFLGIQDIKTSKND
KIAAINQQQYQTKSTKENKFLGSKFRAQMKQLMDELIQSDCHFIRCIKPNETKRANNLIQ
GYVLIQIKYLGVLQAILARKEGFPYRKDFKVLFQQFSGMIEKYRTLSLQKIESQNLDLKN
ISQDILQELFKNNKDVLKHVLVGKTKIFAKDDFGKILDEMLFKWYEQKKSLIFKIIKQFQ
VYQFKKNLKANMKILMKAIKTFQKISAVFKMKCQRKRFLQVKKSTALIYSLMCKNFKKQF
IKQWNIKTKQIIVAQKQKEREQAELLAKQKLEVKQQQNEMNKDEIDQQIDQNSILCNTID
RKDNYNTNLSQEYATISNYNTFNAVNNNQNNIEMKQNYKDLQENYLSSKGEADMNEKMKQ
EFEQIQQKNKEILQDAQLEDGLPQKIKLKSKVESFLNLDNPNMIRPGPNEKSKDCLIDFN
ECNQEMIQKIEQSNYFEIISTIVVIRKYNSTDQNPLQKMLSYQKRQLKKPLTSIDKHYEP
IATKAFSYMLKYAGDKPCEEIHPRIIAWKLAQLILDQDVQEVTDEIFLQVIKQLTNNSEE
NIEQYFKIAALIASCVVLSCRIVFPSMNFFLEQARHYEKSGKEKLMEWCKFILSRIGNSY
NFDENMQFPCYIFKREEMPLKEEFIALENMFSIQIPIHFYGDRQKYFKVESYTKICNMVS
QIGLDLEILYDKNSYGLVEYITVDAVTKVQILDFGMRILDWKAKRYRDRQQYLQKNPGKT
FEIKLYYQCIIFHSPKSQNIDTNLMTYLTYVNEYLHGLYFFDFNTNKDQIQNKLIDYPKE
ITEIDFIVEMSAAKVLADYKIYKKENIILQNCIPNSKIIFIRHEVWKVKIEDQICKLQQI
IKTQRQARTYFLNRMKEYQGKYYFSQKFFCKFSQHPNFLEQKEAICLTKLGYVYIIEQQT
YKQLLEISYRDIKDFSINFYSQSLVLYTEQNIYQIFSQYALNIYYNIKSYCQTLEELDND
NIQEDRNCFQTNENLLNNSNEKTVYDSKNSNQDQKSDNSQVPINMIDKVNDDTIVIEMQQ
YSSNDCKKQQSQKTQKNVRNGNLITPVKNQSTYQNEPQIPNYSANINRGSEEYFDNSPNS
QYSSGQNKLINNIQKNDQKLFQESKINLNKQLQEAQNDTSNIDQTNRSCNLYENLL


>TTHERM_00194050(gene)
ATGCTAGATATAAATACTACATGGATGATTCCGGACAGTGAGTGCTGGATTTAAGTAGGA
GAAGAAGATGCATAAACATAAACAATGTTTGTGAAAGCTAAAATAAAATAAAAACCCAGT
CTTTCAAACATTAATAAGAATAATGTTTAACAATGTTTTGCTGACATAAAAGATGTAGAA
GATAATCGATATGCTAATATAACAAAAGTTAAAATAAATTCAGTTTATTAAGTAAACTAA
GAAGTACCTTAAGGTTATAATGATATGGTAGAAATGGATCACTTGAATTAAGCAGAAATT
CTTATTAATTTATAAAGAAGATACGATTAAGATTTAATATTTACATTTATAGGTCCTACA
CTTGTAGTGATGAATCCTTACAAGTTAATTCCAAAGCATTTTTCAAATGAAACTCGTAAT
ATTTTTTCATAATAAGCAAAACACCAAGGCTACATCGATTATAAAAAAAATGATCCACAT
ACTTATGCTGTAGCTGCTTAATCATATTGTAAGCTTTTTGAGTAAAATAAAAATCAAGCC
ATAGTAATATCAGGTGAGTCAGGTGCAGGAAAGACTGAAAATGCCAAAATATGCATGTGT
TTTCTTACAGGATTAAGCGGATAAGATGCTGAAAGAAGACCTAGTATATAAAATAGTACT
TCTCCAGCTAATAAAAATAAAAATAATATTGAAGATAGAATTTTGGGATGCAACCCTATA
TTAGAGGCGTTTGGAAATGCAAAAACTGTTAGAAATGATAACAGCTCTCGTTTTGGAAAA
TTTGTATCGATTTAAGTAGGGAAAAAATCAAGAAAAATTAAAGGTGCTACAATTTAGAAC
TATTTACTAGAAAAGAGTCGTGTTACCACTCCTGGTCCTGGAGAGCGCGGTTACCACATA
TTTTATCACTTACTCTACTGCGGATAAAACTAACTTTTAGAAAATTTATAATTGGTAGGT
TAATATTCAAAACCACAAAATCTAAATTACTTAAAAGTTAGTAATTGTTATGAAGTATCA
ACTATAAATGACAATGCTCTGTTTAAAGAAGTTGTTGAGGCCTTTCATACTATGGGTATT
AATTAAGAAGAATAGGATACTATTTTTAGGATTATAAGTTCAATCCTATTGTTGGGTAAT
GTCTAATTTGACTAATCCACTTTAACTGACACACAACCATGTACTGTTAAGGATGAAAAG
CTTCTCAAAACAATTTCAGATCTGTTAAAGCTGGATTTTTCATCTCTCTTGAGAACAATT
AACACTGTTACAAGAAAAATAGGATCCTCTGTAATATATTCACCCAAAAAAATAGATGAA
GTAATTTCCTCAAGGGATTCTATTGCTCGTAATATGTATGATAGAATGTTTTCGTGGATA
GTTACTCGTTTGAATAATTCAATTAATATAAAAGGAGAAAATGGCAAAGAAAATGAAAAT
GAAGCTTAACTCTGCATAGGTTTACTTGATATTTTTGGCTTCGAGGTATTCGAAGAAAAC
TCTTTTGAGTAATTCTGTATTAATTATACCAACGAAAAACTATAATAATTGTACATACAA
TACGTATTTAAATCTGAAGAATAGGAATTTATTATTGAAGGACTAGAAAAATACATAAAT
TAACTAGGGTACAAAGATAATTAAAATATCATTGAAGTACTTGATAATCATCCTATTGGT
ATATTTTAGCTTATCGATGAGTCGTCAGCTCTCGCACAGTCTGATGATAAAAAGCTATAT
GAAAGCATCTATAGAATAAATAATGGAAAACCTGAAGTGAAGTTTGTAAATAAAGGAAAT
AAAAAAATTTTTTAGATTGTCCACACAGCAAAACCTGTAGATTATTCAATAGAAGGATTT
AGAGATAAAAATAAAGCTGAAATAAGCTAAGAGCTTTAGTTGACTATAGCTTAAAGTGAT
GATCCTATAGTTTCCTCAATATTTTTAGGTATTTAATTAAATTCGAATATTTATATAAAA
TAGATAATAAGCTGATGATGTGAATTATAATTTTCAAATTTATTAAAAAGATTTAGATTT
ACTTTTTTCTCAATTTTTTTTTAGATTACAATCATCAGAAATCAATTTTCTCAAATTTAA
TTAAAAATTTGATTTTGATCATCAATCTTTTATTTAAGCTAATTCATATTCAAAAAGGAA
TTTAGGATATCAAAACTAGTAAGAATGATAAAATTGCAGCCATTAATTAGTAGTAGTATT
AGACTAAAAGTACAAAGGAGAACAAATTTTTAGGAAGTAAGTTTAGAGCCTAAATGAAGT
AGCTCATGGATGAATTAATCTAATCAGACTGCCATTTTATAAGATGTATAAAACCAAATG
AGACAAAAAGAGCAAATAATTTGATTCAAGGATATGTATTGATTCAAATAAAATATTTAG
GAGTTTTGTAAGCCATTTTAGCTAGAAAAGAAGGATTTCCTTATAGGTAAATATATACTT
GACTAATTAAAAAATAATTCAAAATTTAATTTTAACCAATTTACAGAAAAGACTTCAAAG
TACTATTTTAGCAATTTAGTGGCATGATTGAAAAGTATAGAACTTTAAGCCTTTAAAAGA
TTGAGAGCCAGAATTTGGATTTAAAAAATATATCCCAAGATATCCTCTAAGAGCTTTTCA
AGAATAATAAAGATGTTTTAAAACATGTTTTAGTTGGAAAAACAAAAATATTTGCAAAGG
ATGATTTTGGTAAAATCTTAGATGAGATGCTGTTTAAATGGTATGAATAGAAGAAATCAT
TAATATTCAAAATAATTAAACAATTTTAAGTTTACTAATTTAAAAAAAATCTAAAAGCTA
ATATGAAAATTCTAATGAAAGCTATCAAAACTTTTCAAAAAATTTCTGCTGTATTTAAAA
TGAAATGTCAAAGAAAGAGATTTTTACAAGTTAAAAAATCAACAGCATTAATTTATAGCT
TAATGTGTAAGAACTTTAAAAAACAATTTATAAAATAGTGGAATATTAAAACAAAATAAA
TTATAGTCGCATAAAAATAGAAAGAAAGAGAATAAGCTGAATTATTAGCAAAATAAAAGC
TGGAAGTAAAATAATAATAAAATGAGATGAATAAAGATGAAATAGATCAATAAATTGATT
AAAATTCTATTTTATGTAACACAATAGATAGAAAAGATAACTACAATACAAATTTATCAT
AAGAGTATGCTACTATAAGTAATTACAATACATTTAATGCTGTCAACAATAACTAGAATA
ATATAGAAATGAAGCAAAACTATAAAGATTTGTAAGAAAATTACTTATCATCAAAAGGAG
AAGCTGACATGAATGAGAAGATGAAATAAGAATTTGAATAAATTTAGTAAAAGAACAAGG
AAATTCTTTAAGATGCCCAATTAGAAGATGGACTGCCTTAAAAAATAAAGTTGAAATCAA
AGGTCGAATCATTTTTAAATTTAGATAATCCTAATATGATCCGCCCAGGTCCTAATGAAA
AGAGCAAAGATTGCTTAATTGATTTCAATGAATGCAATCAAGAAATGATCTAAAAAATTG
AATAAAGTAATTATTTTGAAATAATTAGTACTATTGTGGTTATTAGAAAATATAATTCTA
CTGATCAAAATCCATTACAAAAAATGCTTTCTTATTAAAAGAGGCAATTAAAAAAACCTC
TCACAAGTATCGATAAGCATTATGAACCTATAGCAACGAAAGCTTTTTCTTATATGTTAA
AGTAATCATTTAGCTTAAATTAAATAAATTTATAATTTTTTAATTAATTTTATATAGATA
TGCTGGAGATAAACCTTGCGAAGAAATTCATCCCAGAATCATTGCTTGGAAGCTTGCTCA
ACTAATTCTTGATTAGGATGTACAAGAAGTTACTGATGAAATATTCTTGTAGGTTATAAA
ATAGCTAACTAATAATTCAGAAGAAAACATAGAGTAATATTTTAAAATTGCAGCTTTGAT
AGCTAGTTGCGTTGTTTTATCTTGTCGCATAGTATTTCCATCAATGAATTTTTTCTTGGA
ATAAGCAAGGCATTATGAAAAAAGTGGTAAAGAGAAATTGATGGAATGGTGCAAATTTAT
ATTGTCCAGGATCGGAAATAGCTATAACTTTGATGAAAATATGTAATTTCCATGCTATAT
ATTTAAAAGAGAAGAGATGCCATTAAAAGAAGAGTTTATTGCCTTAGAGAATATGTTTTC
TATTCAAATTCCAATTCACTTTTATGGAGACCGCTAAAAATACTTTAAGGTAGAATCATA
TACCAAAATTTGTAACATGGTGAGCCAAATTGGCTTAGATTTAGAAATTCTTTATGATAA
AAACAGTTATGGATTAGTCGAATACATAACTGTTGATGCAGTTACTAAAGTTTAAATTTT
AGATTTTGGAATGAGAATACTTGATTGGAAAGCCAAGAGGTATCGTGATAGATAACAATA
TTTACAAAAAAATCCAGGTAAGACTTTTGAAATAAAACTATATTACCAATGTATCATTTT
TCACAGCCCAAAATCTTAAAATATTGACACTAATCTTATGACATATCTAACATATGTAAA
CGAGTATTTGCATGGATTGTATTTCTTTGATTTTAACACAAACAAAGATTAAATATAAAA
TAAATTAATTGACTACCCAAAAGAAATTACAGAAATTGATTTTATTGTTGAGATGTCTGC
AGCTAAGGTGCTAGCTGATTATAAAATCTATAAAAAGGAAAATATTATCTTACAAAATTG
CATCCCAAATTCAAAAATTATTTTCATAAGACATGAAGTGTGGAAGGTCAAAATCGAAGA
TTAAATATGTAAGTTATAACAAATTATAAAAACTTAAAGACAAGCAAGGACTTATTTCTT
GAATAGGATGAAAGAGTACTAAGGGAAGTACTACTTTTCTTAAAAATTTTTCTGTAAATT
TAGTTAGCACCCAAACTTTTTAGAATAAAAGGAAGCTATTTGCTTGACTAAATTAGGCTA
TGTGTACATTATTGAATAGCAAACATACAAGTAATTGTTAGAAATTTCTTATAGAGATAT
AAAAGATTTTAGCATTAATTTTTATTCCTAATCACTTGTTTTGTATACAGAATAAAATAT
TTATCAAATATTTTCTTAGTATGCTTTGAATATATACTACAACATTAAATCGTATTGCTA
AACTCTTGAAGAATTAGATAATGATAATATCTAAGAAGATAGAAATTGCTTTTAAACTAA
TGAAAATTTGCTAAATAATTCAAATGAAAAAACTGTTTATGATTCGAAAAATTCTAATCA
AGATCAAAAATCAGATAATTCATAAGTACCAATAAATATGATTGATAAAGTTAACGATGA
TACTATTGTAATCGAAATGCAATAATACTCATCTAATGATTGTAAAAAATAATAATCACA
AAAGACTTAAAAAAATGTGAGAAATGGAAATTTAATCACTCCTGTTAAAAATTAAAGCAC
ATACTAAAATGAACCTTAAATACCAAATTATTCAGCTAATATTAATAGAGGAAGTGAAGA
ATATTTTGATAACTCTCCTAACTCATAATATTCAAGTGGCCAAAATAAATTAATTAATAA
CATTTAAAAGAATGATTAAAAATTATTTTAAGAATCAAAGATAAATCTAAATAAATAGTT
ACAAGAAGCTTAAAATGACACAAGTAATATAGACCAAACTAACAGGTCATGCAATTTATA
TGAAAATCTGCTATGA