Identifiers and Description

Gene Model Identifier

TTHERM_00191790

Standard Name

CDC5  (Cell Division Cycle  )

Aliases

PreTt08829 | 15.m00540 | 3697.m00251

Description

Polo-like kinase

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00069 ) protein kinase domain
  • ( PF07714 ) protein tyrosine kinase
  • ( PF00659 ) POLO box duplicated region

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_00191790

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Stentor CoeruleusSteCoe_364450
Tetrahymena borealisEI9_06146.19.997093137033517e-262protein kinase domain-containi
ng protein (675 aa)
OxytrichaContig8263.0.g239.997093137033517e-262Protein kinase domain
SGDYMR001C3.998986577109865e-118CDC5 Polo-like kinase with mul
tiple functions in mitosis and
cytokinesis through substrate
phosphorylation, also functio
ns in adaptation to DNA damage
during meiosis; has similarit
y to Xenopus Plx1 and S. pombe
Plo1p; possible Cdc28p substr
ate
WormBaseWBGene000040429.00055006962023e-115locus:plk-1 Serine/threonine
-protein kinase plk-1 status
:Confirmed UniProt:P34331
protein_id:CCD64438.1
DictyBaseDDB_G02745034.001242549923285e-107plk on chromosome: 2 position
4379150 to 4382891

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00191790(coding)
ATGGATAAGGCAAACGAAGGTAAAGATTAATTAATCATCATTGAAGAAAAAATTTCAAAA
GTAAATGGTGAGATGGCTGTCAAGAAGTATTTACGAGGCAAGCTATTAGGTAAAGGTGGC
TTTGCTAAGTGCTACGAAGTAACAAATTTAGAAACTAAGAAAATTATTGCAGCAAAAATA
ATTCCAAAACAGACCTTAACAAAAAATAGAGCTCGTCAAAAACTCATTTCAGAAATTAAA
ATTCATAAAAGTTTAAATCATTAGCATGTTGTAGCATTTGAACATGTCTTTGAAGATCAT
GAGAACGTATACATTTTACTAGAGCTCTGCACTAACCATACCCTAAACGAATTAATTAAA
AGACGTAAGAGATTGACTGAACTCGAAGTTTAGTGTTATGTTGTTTAAATAGTTAATGCA
CTTAAATATTTACACAGTCATAAAGTAATCCACAGAGATTTAAAACTAGGTAATCTTTTC
CTAAATGAGAAGATGGAAATTAAGCTAGGTGACTTCGGTCTTGCTACAAAGCTAGAATTT
GACGGAGAAAAAAAGCATACAATTTGTGGTACACCTAACTACATTGCTCCAGAAATTTTA
GATGGAAAAACTGGTCATTCTTATTAGGTTGACATTTGGTCATTGGGAGTTATCATTTAT
ACACTCCTAATAGGAAAGCCACCATTTGAAACTCCTGATGTCAAGACCACATACAAAAAA
ATTAGAAATATCTCTTATGGATTCCCTGAAAACGTTCCTATTTCTGATTAGGCAAGAGGC
TTGATTACTAGAATTTTGAATATAGATCCACAAAGAAGACCGACGTTAGATGAAATTATG
AGCTCATCCTTTTTAAATACTGGTGGTACTATTCCTAAAGTACTACCTTTGGCTACTTTG
GCTTGCCCTCCCTCAGCTTCATACACAAAGTAATTCCTTCCATAAGGAAATGCTCTCAAG
CTTAATCAAGCTCCAATGAGACTAACCGATTCAGCATCTTAGTCAACTACAAACATTAAA
GGTAAAAATGCAAGCACTTCTAATCTTTACTCTAAATAAACAACCACAGGTGCAGTCCCA
GATGCCAGTCGCCCACTTGGAGGAACCACTTCAAATTGGAATTAAGTGTCTAGCTAAAAA
GATTAACGTCCACAAACTCAATAATTCTAAAAATCTGACTTTAAGACATCAATGTCAACT
AAAAATATGGGCTCTGGTTCTTAAAACCCTCTTTTCAACCAGACTAATGCCCCTGGATTA
GCAACAGCATAAAGTCTTAATACATTCACCAAAACAAAAAATAACTTTAATAGCACACAA
AAAGGTTTTATGCAAACTGGTACATAAAATTTTGGTAAACCTGTACAACCTGTTTGGGTT
ACTCAATGGGTAGATTACTCAGCTAAATATGGTTTAGGGTATCTTCTTTCTAACGGATGC
AGTGGTGTCTTCTTTAATGACTCAACAAAAGTGATATTAGACCCTACAACCAATAACATA
GAATACATCGAAAGACTTGGAAACGAAAGATAAGACTTCGTTTAGCAATTCACCTTGAAG
GATTATCCTCCTGAGATGAAAAAGAAGGTTACACTCCTATCTCATTTTAAGAGTTACTTG
GAAGAATAAATGCAAAAATAAAACATTCAAATAGAAGTTCCATAATTCTAAGGAGACTTG
CAACCCTATGTTTATGTAAAGAAGTGGATGAAAACTAAACATGCCATTATGTTCCGTCTT
TCAAACAAAATCGTACAAGTAAGCTTCCAAGATAAGACAGAGATTTTGCTTTCTTCAGAA
AATAAAATGGTTACATACGTAGATCGTAAAGGCACTCGTACTGACTATCCATTATCTACA
GCACTAGAAAGCTCTAATACAGAAATGTCAAAACGTCTTAAATATACTAAAGATATACTG
ACTCACATGTTAAATAATAATACCACAAATAACAACAATGGTAGAGGATCAATGACTAAC
GTAAATCCTACCTAGAATGGTACAGAAAAGGAAAATTATAACTGA


>TTHERM_00191790(protein)
MDKANEGKDQLIIIEEKISKVNGEMAVKKYLRGKLLGKGGFAKCYEVTNLETKKIIAAKI
IPKQTLTKNRARQKLISEIKIHKSLNHQHVVAFEHVFEDHENVYILLELCTNHTLNELIK
RRKRLTELEVQCYVVQIVNALKYLHSHKVIHRDLKLGNLFLNEKMEIKLGDFGLATKLEF
DGEKKHTICGTPNYIAPEILDGKTGHSYQVDIWSLGVIIYTLLIGKPPFETPDVKTTYKK
IRNISYGFPENVPISDQARGLITRILNIDPQRRPTLDEIMSSSFLNTGGTIPKVLPLATL
ACPPSASYTKQFLPQGNALKLNQAPMRLTDSASQSTTNIKGKNASTSNLYSKQTTTGAVP
DASRPLGGTTSNWNQVSSQKDQRPQTQQFQKSDFKTSMSTKNMGSGSQNPLFNQTNAPGL
ATAQSLNTFTKTKNNFNSTQKGFMQTGTQNFGKPVQPVWVTQWVDYSAKYGLGYLLSNGC
SGVFFNDSTKVILDPTTNNIEYIERLGNERQDFVQQFTLKDYPPEMKKKVTLLSHFKSYL
EEQMQKQNIQIEVPQFQGDLQPYVYVKKWMKTKHAIMFRLSNKIVQVSFQDKTEILLSSE
NKMVTYVDRKGTRTDYPLSTALESSNTEMSKRLKYTKDILTHMLNNNTTNNNNGRGSMTN
VNPTQNGTEKENYN


>TTHERM_00191790(gene)
ATGGATAAGGCAAACGAAGGTAAAGATTAATTAATCATCATTGAAGAAAAAATTTCAAAA
GTAAATGGTGAGATGGCTGTCAAGAAGTATTTACGAGGCAAGCTATTAGGTAAAGGTGGC
TTTGCTAAGTGCTACGAAGTAACAAATTTAGAAACTAAGAAAATTATTGCAGCAAAAATA
ATTCCAAAACAGACCTTAACAAAAAATAGAGCTCGTCAAAAACTCATTTCAGAAATTAAA
ATTCATAAAAGTTTAAATCATTAGCATGTTGTAGCATTTGAACATGTCTTTGAAGATCAT
GAGAACGTATACATTTTACTAGAGCTCTGCACTAACCATACCCTAAACGAATTAATTAAA
AGACGTAAGAGATTGACTGAACTCGAAGTTTAGTGTTATGTTGTTTAAATAGTTAATGCA
CTTAAATATTTACACAGTCATAAAGTAATCCACAGAGATTTAAAACTAGGTAATCTTTTC
CTAAATGAGAAGATGGAAATTAAGCTAGGTGACTTCGGTCTTGCTACAAAGCTAGAATTT
GACGGAGAAAAAAAGCATACAATTTGTGGTACACCTAACTACATTGCTCCAGAAATTTTA
GATGGAAAAACTGGTCATTCTTATTAGGTTGACATTTGGTCATTGGGAGTTATCATTTAT
ACACTCCTAATAGGAAAGGTAATCATCATAAAAATTTACAAATTAATCCAAAAACAGCTA
TTTGCATGAGAAAAAGCCCTATCCCAAACTAGAGTTATAATTGGAGTAATACACAAAGAT
AATAAGCAAGTATTACATTAATTTTGAAAGCAAATAGTTGAAGAAAATAAGAAATTAAAT
TCTATTTACTAACTGAATAAATTGATATCTATATAGCTATATATAAAATAAGAAAGAAAC
AAAGAAAAAATATTTATTTATTTCACAGCTTATTTGCAAAATGATAATCAAATATATTTT
TCACATACTTTCTTTTCAAAAAAATAAATAATCAATCAATCAATCAAACAAACAAACAAA
TATTTATTTTTTGAAAGTAGAAGGGAGCGAGCAATTCAACTAAACACTCTATTTATAAAT
TAGCATGATACAATAAAAAGAGCTAATATTTATATAGAAAAAAAAAATTATCAAAAATAG
ACTGAATCAGAATTATTTGAGATAAGCATACAAATTATTTATTTTTAAATTTTAGAAATT
AAATTAATTTAAGCTAATATTGAGCTAAGTTTTTAAATCACTTCTTTAAATTGAAATTCT
TTTGATGGGCTTATTTTTTATACTTAATCGAAAACTTAGCGAGTATTCATTTCAATAGCA
AATAACATTTTTTAATGCAGACAAATAAATTATCTTCGCTTTTAAAATATTTTTCTTTTA
CAAAAAACTGCTTAACTACAAAATAGAGCTTCAATAAGATTTAATTTTTTTAGCAAATCT
TTTCAAATCAAGTATTTTTTTTTTAAAGGCTAATAAATATTCAATAACTACTTAATTTTA
AAATAGCTATGATTAAGGGATGTAAAATTTTTAAAGCGATTTTAAGCAGTCAAAATAAAT
CCTATAAAAATAAATTAAACATAATTGTATATAATAGCCACCATTTGAAACTCCTGATGT
CAAGACCACATACAAAAAAATTAGAAATATCTCTTATGGATTCCCTGAAAACGTTCCTAT
TTCTGATTAGGCAAGAGGCTTGATTACTAGAATTTTGAATATAGATCCACAAAGAAGACC
GACGTTAGATGAAATTATGAGCTCATCCTTTTTAAATACTGGTGGTACTATTCCTAAAGT
ACTACCTTTGGCTACTTTGGCTTGCCCTCCCTCAGCTTCATACACAAAGTAATTCCTTCC
ATAAGGAAATGCTCTCAAGCTTAATCAAGCTCCAATGAGACTAACCGATTCAGCATCTTA
GTCAACTACAAACATTAAAGGTAAAAATGCAAGCACTTCTAATCTTTACTCTAAATAAAC
AACCACAGGTGCAGTCCCAGATGCCAGTCGCCCACTTGGAGGAACCACTTCAAATTGGAA
TTAAGTGTCTAGCTAAAAAGATTAACGTCCACAAACTCAATAATTCTAAAAATCTGACTT
TAAGACATCAATGTCAACTAAAAATATGGGCTCTGGTTCTTAAAACCCTCTTTTCAACCA
GACTAATGCCCCTGGATTAGCAACAGCATAAAGTCTTAATACATTCACCAAAACAAAAAA
TAACTTTAATAGCACACAAAAAGGTTTTATGCAAACTGGTACATAAAATTTTGGTAAACC
TGTACAACCTGTTTGGGTTACTCAATGGGTAGATTACTCAGCTAAATATGGTTTAGGGTA
TCTTCTTTCTAACGGATGCAGTGGTGTCTTCTTTAATGACTCAACAAAAGTGATATTAGA
CCCTACAACCAATAACATAGAATACATCGAAAGACTTGGAAACGAAAGATAAGACTTCGT
TTAGCAATTCACCTTGAAGGATTATCCTCCTGAGATGAAAAAGAAGGTTACACTCCTATC
TCATTTTAAGAGTTACTTGGAAGAATAAATGCAAAAATAAAACATTCAAATAGAAGTTCC
ATAATTCTAAGGAGACTTGCAACCCTATGTTTATGTAAAGAAGTGGATGAAAACTAAACA
TGCCATTATGTTCCGTCTTTCAAACAAAATCGTACAAGTAAGCTTCCAAGATAAGACAGA
GATTTTGCTTTCTTCAGAAAATAAAATGGTTACATACGTAGATCGTAAAGGCACTCGTAC
TGACTATCCATTATCTACAGCACTAGAAAGCTCTAATACAGAAATGTCAAAACGTCTTAA
ATATACTAAAGATATACTGACTCACATGTTAAATAATAATACCACAAATAACAACAATGG
TAGAGGATCAATGACTAACGTAAATCCTACCTAGAATGGTACAGAAAAGGAAAATTATAA
CTGA