Identifiers and Description

Gene Model Identifier

TTHERM_00188500

Standard Name

GTR4 (Glucose TRansport 4)

Aliases

PreTt08600 | 15.m00311 | 3697.m00023 | GTP4

Description

GTP4 MFS transporter; Major facilitator superfamily protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• integral component of membrane (IEA) | GO:0016021

Molecular Function

• transporter activity (IEA) | GO:0005215

Biological Process

• transport (IEA) | GO:0006810

Domains

• ( TIGR00898 ) cation transport protein
• ( TIGR00880 ) Multidrug resistance protein
• ( PF06930 ) Protein of unknown function (DUF1282)
• ( PF07690 ) transporter, major facilitator family
• ( PF00083 ) transporter, major facilitator superfamily
• ( TIGR00879 ) MFS transporter, sugar porter (SP)
• ( TIGR00791 ) transporter, gluconate:H+ symporter (GntP) family
• ( TIGR00023 ) acyl-phosphate glycerol 3-phosphate acyltransferase
• ( TIGR00895 ) MFS transporter, aromatic acid:H+ symporter
• ( TIGR00883 ) MFS transporter, metabolite:H+ symporter (MHS)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11%

TetraMine Data

TTHERM_00188500

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02320.1	2.000147820282363e-173	sugar transporter (527 aa)
Oxytricha	Contig12280.0.g23	3.0011931572567413e-53	Sugar (and other) transporter
DictyBase	DDB_G0278261	1.9993007828132465e-27	DDB_G0278261 on chromosome: 3 position 577308 to 579437
SGD	YDL194W	3.0007793728221555e-22	SNF3 Plasma membrane low gluco se sensor that regulates gluco se transport; contains 12 pred icted transmembrane segments a nd a long C-terminal tail requ ired for induction of hexose t ransporters; also senses fruct ose and mannose; similar to Rg t2p
WormBase	WBGene00019979	9.995317835403734e-19	status:Partially_confirmed U niProt:O44616 protein_id:CCD 68888.1
Stentor Coeruleus	SteCoe_2075	1.1548224173015786e-17

General Information

Paragraph No	Gene Name	Paragraph Text
27	GTR4	GTP4 has only one known functional domain and is a member of the sugar transporter family, a subset of the major facilitator superfamily (E-value: 5.4e-36). This protein appears to be responsible for transporting sugar across the plasma membrane in response to changes in the electrochemical gradient, specifically in sugar uptake. Paragraph by: Kathleen Beardsworth and Kristen Keller (undergraduates), Keck Science Department, Claremont Colleges.

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00188500(coding)
ATGAAAAGTCCATCAAGCTTAAATAATATGGATATCACAACTGAAGATGGCTAAAAATCT
TCTAAAAAATAGGAAGAATAGGAATATATATCGTTTTTGTATATATTAATTAATGTAATT
GTTTCGAATCTAGGAATTTTATATTTTGGATACCACCTCTCAGTTATGTCTTTAGCTTAA
GATACCGTTTTTACTGTATTTGAAGTTAAAGAAAGTTAACATAACTTCTACTCTTCTCTT
CTTGCTGCTGCTATTCCTTTTGGAGCTATATTTGGAGCAATCATACCTGGTAGCTTTCTT
TCTAATAGCTCCAGAAAAAACTCTATGATTTTTGCTGATGCTATTGGAACCATTTTTGGA
CTCTTAGTCTTAACTCGTGATATAAATATGCTTGTTTTAGCAAGACTATGTGCAGGATTT
GTCATAGGACTAAATAGCTCACTTGTTCTTAAATATGTAAATGAAATTACTCCAATTAGT
TTAACAGGAGTTATGGGTATAGTCTTTAGTATATCTTTGACTTTAGGTATAGTTATAGCA
AGTTTAAATGGATAGTTTTTTAGTCAAAATCCTTCTTAAGAAGATTAATACTGCTTTTTT
GTACTATTATTTCCATTAATATTTACTATTAGCCGTCCTATCTTATTTTAAGTTTTCTTC
AATCACGAAACTCCTTTTTATTACATCCTTAACAACCAACCTGATAGCTGCAAATAATTA
CTACAAATATTATATAAATCTCAATATGTTGACAAAATACTTTTAGAAGTTTAGTAAGAA
GTAATTAAGCAAGGCAGCAAAGACACTTCCAAGAGTTATAATATTAAGCGCTTGTTCATA
GGATGTACCTTGCTAATATTTTAGTAGTTTTCTGGAATAAATGCAGTTATTATGTTTTTA
GGTTAAATATTTTAAAAAGAACATTTTTCATTTAGAATGACAAATTTACTTTCACTACTT
TCTAATTTTATTTACTTAATAGCCTCAATTCTTAGTACGTACTTTGTAAAAAAGTATACA
AGGAGAGCCATTCTTATAACAGGTTCTTCATTTGCTGGAATATTTCTGCTCCTATTAGCT
CTTTTATAAATTATTGACATATAATAAATTTCTTTTCTTGCATTTTTTTTTATTAGCTGT
TACTTTGTTGCCTTCAACTTTTCTCTTGGCCCTGTCATTTGGTTATATAGTTCAGAAATT
CTTTCATCTAAAGAATTTAGCATAGCTACAACATTGAACTGGATAAGTGCAACAATAGTA
GTTGTTTCAATACCATATTTTGATCATTTGTGGCCACTATTCATTTTTTTCTCTGTTGTT
TGCTTTTCTTGTGCAACCTTCACTTTATTCTTGGTTAAAGAAACTAAAGATAAAAGCAAA
TTAGAGATACTTCATTTATATGATCCTTAACAAAAAGATCAAGGTGAGTATTCTAGTATT
GCTTTAAACACTTCTGATCAAAAAAATTACGTAGACTGA

>TTHERM_00188500(protein)
MKSPSSLNNMDITTEDGQKSSKKQEEQEYISFLYILINVIVSNLGILYFGYHLSVMSLAQ
DTVFTVFEVKESQHNFYSSLLAAAIPFGAIFGAIIPGSFLSNSSRKNSMIFADAIGTIFG
LLVLTRDINMLVLARLCAGFVIGLNSSLVLKYVNEITPISLTGVMGIVFSISLTLGIVIA
SLNGQFFSQNPSQEDQYCFFVLLFPLIFTISRPILFQVFFNHETPFYYILNNQPDSCKQL
LQILYKSQYVDKILLEVQQEVIKQGSKDTSKSYNIKRLFIGCTLLIFQQFSGINAVIMFL
GQIFQKEHFSFRMTNLLSLLSNFIYLIASILSTYFVKKYTRRAILITGSSFAGIFLLLLA
LLQIIDIQQISFLAFFFISCYFVAFNFSLGPVIWLYSSEILSSKEFSIATTLNWISATIV
VVSIPYFDHLWPLFIFFSVVCFSCATFTLFLVKETKDKSKLEILHLYDPQQKDQGEYSSI
ALNTSDQKNYVD

>TTHERM_00188500(gene)
ATGAAAAGTCCATCAAGCTTAAATAATATGGATATCACAACTGAAGATGGCTAAAAATCT
TCTAAAAAATAGGAAGAATAGGAATATATATCGTTTTTGTATATATTAATTAATGTAATT
GTTTCGAATCTAGGAATTTTATATTTTGGATACCACCTCTCAGTTATGTCTTTAGCTTAA
GATACCGTTTTTACTGTATTTGAAGTTAAAGAAAGTTAACATAACTTCTACTCTTCTCTT
CTTGCTGCTGCTATTCCTTTTGGAGCTATATTTGGAGCAATCATACCTGGTAGCTTTCTT
TCTAATAGCTCCAGAAAAAACTCTATGATTTTTGCTGATGCTATTGGAACCATTTTTGGA
CTCTTAGTCTTAACTCGTGATATAAATATGCTTGTTTTAGCAAGACTATGTGCAGGATTT
GTCATAGGACTAAATAGCTCACTTGTTCTTAAATATGTAAATGAAATTACTCCAATTAGT
TTAACAGGAGTTATGGGTATAGTCTTTAGTATATCTTTGACTTTAGGTATAGTTATAGCA
AGTTTAAATGGATAGTTTTTTAGTCAAAATCCTTCTTAAGAAGATTAATACTGCTTTTTT
GTACTATTATTTCCATTAATATTTACTATTAGCCGTCCTATCTTATTTTAAGTTTTCTTC
AATCACGAAACTCCTTTTTATTACATCCTTAACAACCAACCTGATAGCTGCAAATAATTA
CTACAAATATTATATAAATCTCAATATGTTGACAAAATACTTTTAGAAGTTTAGTAAGAA
GTAATTAAGCAAGGCAGCAAAGACACTTCCAAGAGTTATAATATTAAGCGCTTGTTCATA
GGATGTACCTTGCTAATATTTTAGTAGTTTTCTGGAATAAATGCAGTTATTATGTTTTTA
GGTTAAATATTTTAAAAAGAACATTTTTCATTTAGAATGACAAATTTACTTTCACTACTT
TCTAATTTTATTTACTTAATAGCCTCAATTCTTAGTACGTACTTTGTAAAAAAGTATACA
AGGAGAGCCATTCTTATAACAGGTTCTTCATTTGCTGGAATATTTCTGCTCCTATTAGCT
CTTTTATAAATTATTGACATATAATAAATTTCTTTTCTTGCATTTTTTTTTATTAGCTGT
TACTTTGTTGCCTTCAACTTTTCTCTTGGCCCTGTCATTTGGTTATATAGTTCAGAAATT
CTTTCATCTAAAGAATTTAGCATAGCTACAACATTGAACTGGATAAGTGCAACAATAGTA
GTTGTTTCAATACCATATTTTGATCATTTGTGGCCACTATTCATTTTTTTCTCTGTTGTT
TGCTTTTCTTGTGCAACCTTCACTTTATTCTTGGTTAAAGAAACTAAAGATAAAAGCAAA
TTAGAGATACTTCATTTATATGATCCTTAACAAAAAGATCAAGGTGAGTATTCTAGTATT
GCTTTAAACACTTCTGATCAAAAAAATTACGTAGACTGA