Identifiers and Description
Gene Model Identifier
TTHERM_00112430
Standard Name
MYO1 (MYOsin)
Aliases
PreTt27057 | 8.m00317 | 3812.m02353
Description
Myosin heavy chain; molecular motor involved in phagocytosis and macronuclear elongation; has putative ATP-binding and phosphorylation sites; member of proposed Class XX, distinct from previously defined myosin classes, putative
Genome Browser
Gene Ontology Annotations
Cellular Component
Molecular Function
Biological Process
Domains
No Data fetched for Domains
Gene Expression Profile
Homologs (v.2006 protein sequences)
| Source | Identifier | Score | Description |
| ParameciumDB | GSPATP00005503001 | 9.9996643883079e-124 | Paramecium tetraurelia GSPATP0
0005503001 protein
|
| TAIR | AT1G17580 | 3.0004252253962e-97 | myosin, putative
|
| DictyBase | DDB0188056 | 1.99970314379378e-94 | myoE myosin IE
|
| DictyBase | DDB0216200 | 1.99970314379378e-94 | myoE myosin IE
|
| IPI(HUMAN) | IPI:IPI00419779.3 | 1.00024349209755e-91 | 03693 Tax_Id=9606 Myosin IC
|
| WormBase | T10H10.1 | 3.00013824557326e-90 | WBGene00002039 hum-6 myosin
|
| ToxoDB | 65.m01195 | 2.00068212212836e-88 | Toxoplasma gondii WD-40 repeat
myosin-like protein, putative
|
| FlyBase | FBgn0010246 | 6.99704686404971e-88 | |
| SGD | YAL029C | 3.00058550969612e-80 | MYO4 SGDID:S000000027, Chr I f
rom 92271-87856, reverse compl
ement, Verified ORF, "One of t
wo type V myosins; required fo
r mother-specific HO expressio
n, for the bud tip localizatio
n of ASH1 and IST2 mRNA; facil
itates growth and orientation
of ER tubules along with She3p
"
|
| CryptoDB | EAK90414 | 6.996899116468e-76 | Cryptosporidium parvum (Iowa)
protein EAK90414
|
| PlasmoDB | MAL13P1.148 | 2.00029942441036e-74 | Plasmodium falciparum 148
|
General Information
| Paragraph No | Gene Name | Paragraph Text |
| 10 | MYO1,
MYO12,
MYO11,
MYO10,
MYO9,
MYO8,
MYO5,
MYO4,
MYO3,
MYO2,
MYO13 | Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4). |
Associated Literature
- Ref:17688250: Hosein RE, Gavin RH (2007) Myo1 localizes to phagosomes, some of which traffic to the nucleus in a Myo1-dependent manner in Tetrahymena thermophila. Cell motility and the cytoskeleton 64(12):926-35
- Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
- Ref:15810016: Hosein RE, Williams SA, Gavin RH (2005) Directed motility of phagosomes in Tetrahymena thermophila requires actin and Myo1p, a novel unconventional myosin. Cell motility and the cytoskeleton 61(1):49-60
- Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43
- Ref:11128708: Williams SA, Hosein RE, Garcés JA, Gavin RH (2000) MYO1, a novel, unconventional myosin gene affects endocytosis and macronuclear elongation in Tetrahymena thermophila. The Journal of eukaryotic microbiology 47(6):561-8
- Ref:9627986: Garcés J, Gavin RH (1998) A PCR screen identifies a novel, unconventional myosin heavy chain gene (MYO1) in Tetrahymena thermophila. The Journal of eukaryotic microbiology 45(3):252-9
Sequences
>TTHERM_00112430(coding)
ATGAATAAAAGTTATTAAGAATGGATTAATCCTAATGTAGAGTGTTGGGTTTGGCTCAAA
TATGAAAATTCTTAGCAAAATTAAAACAATTCTGAAAATGGATAATATTTCTAGTGCGTT
ATTCAATCAGTATAAAAAGAAAAGAATTTAGCAAAGATAAAAGTTACTTGTAAAGAAGAA
TAATTAGGAAATCGAATATCAGATTAAGCAATTAATGGATAATTAGATGTTTAATTTGAA
AGATTATTAGAAAAGGAAATTATGGTTGATTCTCTTCAAACTTTAGGTTATTCAGATATG
GTTCATATGAAGTATTTAAATGAGGCTGAAATAATCAATAATTTGAGAAAGCGATATTAA
AATAATATGATTTTCACATATATTGGACCAACTTTGGTAGTTATGAATCCATATAAAGAA
ATAGAAGGAGTATAAGATAATCAAGTAATAGATAAAATAAAATCTGATCTAGGCATAAAA
TTTGAAGAGGATTTCAAAATGAATAATCTGAGCACCAACTAAAATATTATAAACACACCT
CATACATATACTGTAAGCGGATTAGCCTACAAATAAATGTTTAGCAATAAGAAAAATTAA
GCAATAGTTATATCAGGCGAAAGTGGAGCAGGTAAAACAGAAAATGCTAAATTATCGATG
CAATTTTTAACAAGTTTGAGTTCAGGGTCTGATAAATAAAATGATTTACTCAATTAATTA
AAGACTCAAACAGCTAAGAATATTCTATTAGAAGAGTTTAACTAATTTGCAATAGAAGTA
AAAATACTTGCTTGTAATCCTATTCTAGAAGCTTTTGGTAATGCTAAAACAGTAAGAAAT
AATAATTCCTCTAGATTTGGTAAATACGTAAAAATCTACATAGATAAAACATCTTAAAAG
ATAAATGGAGCCTCCATTGATAGCTACTTACTCGAAAAGAGCAGAATACCTTGTCCAGGA
AAGGGAGAGAGAAATTATCACATTTTTTACCACATGCTAAAAGGAAATCAAGAACTATCT
AATTTGAGATTGAGTTAGTTCAAAAATTTATCTGATTTTGATTATCTAAAGAAAAGTGAC
TGCTTTGAGGTTGAGAACATTTAAGATGCTAAACTCTATTTGGAAGTAAAGAAGTCCTTC
AGATAAATGAATTTCTCTAACTAAGAGTAAGAAGCTATATTTTCTCTAATATCTGCGATA
CTACTGTTAGGCAATGCAAATTTAGACTCATCAAAAGCTAGCGACACTCAGGCTCCAACT
TTTTTGAACATGAGTTTACCGACACATCATAAAGAATTCAAAAATGCCTCTGAGTTACTC
TAAGTTAATCCTAAAGACCTTGAAGAGTCTTTAGTATTTAAGGTAAGGAAAGTTGGAACT
ACAGTAATTAAATCTCCATAAACTGCTGAAGAATGCTTGTCTATGAGAGACAGTCTAAGT
AAAAATCTATATGATAGTCTTTTTAACTTTTTGGTTTGGAAGTTAAATTAAAATTTGTTG
CCACCTTAAGATTTGCTAAATAAATCATTAAGCATAGGCCTTTTAGATATATTTGGTTTT
GAGAGCTTTGATATAAACTCATTTGAGCAGCTTTGCATTAATTTTACCAATGAAAAATTT
TAGTAATTGTATGTTTAATATGTTTTCAAAAGCGAAGAAGAAGATTATAAATAAGAAGGA
ATTTTGGATGTATTTTCTGATTTATAATATTAAGAGAATTAGCTCATTATTGATACAATT
GAAAAAAAACCCAATGGAATCATGGTGCTTTTAGATGAAAATTGCTCATTGGGATCAGGG
ACGGATGATTCTTTTTTAAATTAAATTACAAAAAACCACTCTAAAAATCAACTTGTCAGC
TTCCCTAAAAAAGATAAATATTCTTTCAGCCTTAGTCATACAGCAAAACAAGTTGTATAT
GATGTGCGCGGATTTAGAGATAAAAATAAAGATGAAGTGAGTACCGAAGTAGAAAAATGT
CTTTAAAGTAGTAAATGTCCAGTTATTGCGAATTTATTATCTTATTAAGGGTCTTAAACT
TAGTAGAATAAAGAAACTTAAAATCTTCAAAATTTTGGAAATAATTTAAATTTTAAAAAA
GCTGAAATTAGTAATCAAATGAACTCAAGTAAAAAGAATGAATTAATGATAGAATTGAAT
AATAGCGATGTTCACTTCATAAGATGTATAAAACCAAACGAAGAAAAGAAAAAGAATTTT
TTTAAGTATGATTATGTTTATTAGCAAGTACAGTATTTAGGCATACTTGATTCCATTAAA
ATCCGCAAAGTTGGATATTCTTACAGAATGACTTATGAAAACTTTTTCTTAGAATACCAA
GAACTGGGATAGAAAACAAAAGGATTAACATTGTAGAAGGTTTAGCAATAAAAGTTAGAT
TTAAAATAATTAATTACAACAGAAATATTTGAAAAGACCAATTTATTGCAAAATAAATAA
CTTCCTTAGAAATGTGTAGCATTTGGAAAAACAAAAATATTTCTCAAAAATGAAGAAATA
CTTCCATAAGAATTTAATGAAAATAAAAAATTAATTAATTAAATTGCAATCATTTGCTAG
AATGGCTATTTAAAGATAAAAATTCCTAAGGAAAAAGAAATCAATATTAAAAATGAAGAA
GCTTATTAGGCTAAGAATGTTGGGATAAGGAATCTCTGCATTTAGTAAATTAAATATTAT
CGTAACCCAAATAAAACTAAGCCTGTTGTTCAAAATTAAACATCTACAATTTAGTAAAAT
AAATAGTAAAATCAACAACCTTAAAAAAGCCAAAATTAAGTTACTTCATCATTTTAAGTA
AATAATTAAATGATGCAATAAAAATAAAGTCTTGTAGGCCAATAAATTTAATCTATTGTA
AACGAGCTTAATTTAGGTGAGATATAAATTAATAAAACCTAACAAGATTTAAAAGACTTT
AGAAAATCAAAGATTATACCTTAAGTTAACTTGAATCCATCACATAGTAAGAGGGCCAGC
AATGCTTGGAGATAAACCCTAATTGCAAGTAGTAGTTAAAATAAAATTAATAAAGATTTG
TAGCTATCTGAATTAGGAGAGTAGAAGCTGATAAATATGAAAGAAACAACTGACTAAAAA
GAAAAAATTAAATATACTAAACCTCTGATATTATAATTTACAGAGTATAACCCTGCTTAT
TAGTATGCAGAGTTTAATATGGAGAGTGCAATAGATTTAGAAGATGTTCCTAATAGTTTA
GATTTTGAGGGTGAATTAAATGATTTGATAAGTGAAGAAATCATTCAATAAATAAAAAAA
AATAACTTTTATTCACACCTTTCTTTTATTCTTGCAAAAAGAACAAAATGGGGAATCACA
CAAACTTAAGAGAAAATAATGAGGCACTAGCTTAAACCAATTTCAAATCCACTAACAAAT
ATTGCTGATTTGAAGAATATAATCACCTATGAAGACACAAAAGATGCTGTTTAATCAATT
AGGAGTATTATTCAATAAAATAATTTATATAATGACACATCAACATAGACTTAAAGACCA
ATTAATTATGAAGATGCTAGAACTGGAAAATTAGATAAGTAAGTATCTAAATAAATTACT
AACGATTAATCACAAAAATTAGCAACTGTCTTTTCGAAATATTCTCTGATGAACCCAAGA
AAAGCTAGTGTTAGAGACACAAACTCACTTGAACAAATTGTCCTATAATAAAGAAAACTT
ACAAAATTAATTTAGTATAAAAAATTTTCTCCTTCAGAAAAAGCTATTAACATATTTAAA
ACTCTCTTAAAGTGCACAGGAGAAAGAAAATCCCGATATAACAGACACAACAATATCATA
AAGCTTCTTACCCTTTGTAACGAAGAGTCAATCGACCTAAAAGAAGAAGTTTACGTTTAA
TTATGCAAATAATTAAGTGCAAATGATAAAAAGGAGTCAAGAATAAAATATTTAAAGCTG
TTTGCTATTATAAGCAGCATACTGCCAACAACCAGTAGATTTTATTATCCTTTACTTCAC
TTTTTATATATGAGAAATACAGATACTCAAATAGAATAGGATGAGAGAAAATGTGAGTAA
ATACAAAGAGGATGCATCCCAACTGATACTGAAATTGTAATGATTGAGAATAAGAAACAA
ATTTTGATTAGAGTTTATCTTCTAAATGAAATCCCAATTACTGTAGGAGTAGAAAGCTAT
ACTAGTGTGAAGATGCTTAAGCAGGAGCTACTTTAGAAAATAGGTATAACCTAAAGACAT
GAATATTATGGCCTTATGGAAGTAAGAAACAATATTAAGAAAAAGAGAAAAGAAACGAGA
TTTATAGATGAAAGTGAGAGAGTAATGGATGTGATAGCTTTTTGGGAAAATGAGTAGTAT
TTATTTGGATCTCAATTAAATTCTTCTTTCATACATAGCAACTCAAAATAAAATGATGAA
GGTATTGAGCAATTCAACCTTTAAAATTATTAGGATCTTGAAGGACTTAAAATTTACCTT
GGAATCAGAATACTTTTTTCATTTTAAGAAAACGATAAAGAAGCAATAAGCGTTTTCTAC
ACTTAGCTATCTTCAGAAGTACTTGAAGGAAAGTATGCACCTTTGGAGGAAAAAGATTAC
TTGAATTTGGCTGCTTTATAACTGTGCATAGATTTTCCAAGAGACGTCATTTTAAAAGAA
ATATCTAAAAGATAGAGTATCAATGCAGATAGTGGGTCTCCATAAAGAACATAGAGTAAT
TTTTTGAGTGCTACTAGCTAAAGTGAAAGCGGTGCATCACAGCTTAAAAAGCTTTCTTAT
TAAGATATTGAACAGATTGATGAATAAGATGAATACGAACAATTCATATAAAATAGAAAT
GAAATTTTAATTGATCCGGTTTTTTACATACCAGCTAAAATGTATTTCTAAAAAGATATT
CAGTAATGGTAACACTTAATACTATAGAATTTGGTTGATAATAGACTTTTAAAGAAAGAG
TACACTCCATCTTAAGCAAAGTTAGCCTACATACTTTATCTTAGTAAGTAAGATTTGTTT
ATGAGTACAATATTTAGAGATGTAAAATACCAAAGAATCAAAATTAAAACACTAAATGAC
ACACTTTCTTCTAAAGAAAAATATGAGCAAATGATTTAATAAAATTAACAAATTCCCATT
AAAGACGAGATACTTTTAGCAATAAACCCATCTAATATTCTGATGTGCGATTCTATAGGT
TTAAATAGACCAAAAAGAAGAGTGCAAATTAAAAATATCTAAAAATTTTGCTGCACTGAG
AAGGAAGTTATAGTAATATCTCATGATAATACAAAACATATTTTTGAAACTCCCCAATAC
TGTAGAGAAATAGCTTTCTTAATTCGCTCTTACTTGAGAATATTTTATTAAAAATAATAG
TAACAACAATAATAAGAAAAAAGTCAATGA
>TTHERM_00112430(protein)
MNKSYQEWINPNVECWVWLKYENSQQNQNNSENGQYFQCVIQSVQKEKNLAKIKVTCKEE
QLGNRISDQAINGQLDVQFERLLEKEIMVDSLQTLGYSDMVHMKYLNEAEIINNLRKRYQ
NNMIFTYIGPTLVVMNPYKEIEGVQDNQVIDKIKSDLGIKFEEDFKMNNLSTNQNIINTP
HTYTVSGLAYKQMFSNKKNQAIVISGESGAGKTENAKLSMQFLTSLSSGSDKQNDLLNQL
KTQTAKNILLEEFNQFAIEVKILACNPILEAFGNAKTVRNNNSSRFGKYVKIYIDKTSQK
INGASIDSYLLEKSRIPCPGKGERNYHIFYHMLKGNQELSNLRLSQFKNLSDFDYLKKSD
CFEVENIQDAKLYLEVKKSFRQMNFSNQEQEAIFSLISAILLLGNANLDSSKASDTQAPT
FLNMSLPTHHKEFKNASELLQVNPKDLEESLVFKVRKVGTTVIKSPQTAEECLSMRDSLS
KNLYDSLFNFLVWKLNQNLLPPQDLLNKSLSIGLLDIFGFESFDINSFEQLCINFTNEKF
QQLYVQYVFKSEEEDYKQEGILDVFSDLQYQENQLIIDTIEKKPNGIMVLLDENCSLGSG
TDDSFLNQITKNHSKNQLVSFPKKDKYSFSLSHTAKQVVYDVRGFRDKNKDEVSTEVEKC
LQSSKCPVIANLLSYQGSQTQQNKETQNLQNFGNNLNFKKAEISNQMNSSKKNELMIELN
NSDVHFIRCIKPNEEKKKNFFKYDYVYQQVQYLGILDSIKIRKVGYSYRMTYENFFLEYQ
ELGQKTKGLTLQKVQQQKLDLKQLITTEIFEKTNLLQNKQLPQKCVAFGKTKIFLKNEEI
LPQEFNENKKLINQIAIICQNGYLKIKIPKEKEINIKNEEAYQAKNVGIRNLCIQQIKYY
RNPNKTKPVVQNQTSTIQQNKQQNQQPQKSQNQVTSSFQVNNQMMQQKQSLVGQQIQSIV
NELNLGEIQINKTQQDLKDFRKSKIIPQVNLNPSHSKRASNAWRQTLIASSSQNKINKDL
QLSELGEQKLINMKETTDQKEKIKYTKPLILQFTEYNPAYQYAEFNMESAIDLEDVPNSL
DFEGELNDLISEEIIQQIKKNNFYSHLSFILAKRTKWGITQTQEKIMRHQLKPISNPLTN
IADLKNIITYEDTKDAVQSIRSIIQQNNLYNDTSTQTQRPINYEDARTGKLDKQVSKQIT
NDQSQKLATVFSKYSLMNPRKASVRDTNSLEQIVLQQRKLTKLIQYKKFSPSEKAINIFK
TLLKCTGERKSRYNRHNNIIKLLTLCNEESIDLKEEVYVQLCKQLSANDKKESRIKYLKL
FAIISSILPTTSRFYYPLLHFLYMRNTDTQIEQDERKCEQIQRGCIPTDTEIVMIENKKQ
ILIRVYLLNEIPITVGVESYTSVKMLKQELLQKIGITQRHEYYGLMEVRNNIKKKRKETR
FIDESERVMDVIAFWENEQYLFGSQLNSSFIHSNSKQNDEGIEQFNLQNYQDLEGLKIYL
GIRILFSFQENDKEAISVFYTQLSSEVLEGKYAPLEEKDYLNLAALQLCIDFPRDVILKE
ISKRQSINADSGSPQRTQSNFLSATSQSESGASQLKKLSYQDIEQIDEQDEYEQFIQNRN
EILIDPVFYIPAKMYFQKDIQQWQHLILQNLVDNRLLKKEYTPSQAKLAYILYLSKQDLF
MSTIFRDVKYQRIKIKTLNDTLSSKEKYEQMIQQNQQIPIKDEILLAINPSNILMCDSIG
LNRPKRRVQIKNIQKFCCTEKEVIVISHDNTKHIFETPQYCREIAFLIRSYLRIFYQKQQ
QQQQQEKSQ
>TTHERM_00112430(gene)
ATGAATAAAAGTTATTAAGAATGGATTAATCCTAATGTAGAGTGTTGGGTTTGGCTCAAA
TATGAAAATTCTTAGCAAAATTAAAACAATTCTGAAAATGGATAATATTTCTAGTGCGTT
ATTCAATCAGTATAAAAAGAAAAGAATTTAGCAAAGATAAAAGTTACTTGTAAAGAAGAA
TAATTAGGAAATCGAATATCAGATTAAGCAATTAATGGATAATTAGATGTTTAATTTGAA
AGATTATTAGAAAAGGAAATTATGGTTGATTCTCTTCAAACTTTAGGTTATTCAGATATG
GTTCATATGAAGTATTTAAATGAGGCTGAAATAATCAATAATTTGAGAAAGCGATATTAA
AATAATATGATTTTCACATATATTGGACCAACTTTGGTAGTTATGAATCCATATAAAGAA
ATAGAAGGAGTATAAGATAATCAAGTAATAGATAAAATAAAATCTGATCTAGGCATAAAA
TTTGAAGAGGATTTCAAAATGAATAATCTGAGCACCAACTAAAATATTATAAACACACCT
CATACATATACTGTAAGCGGATTAGCCTACAAATAAATGTTTAGCAATAAGAAAAATTAA
GCAATAGTTATATCAGGCGAAAGTGGAGCAGGTAAAACAGAAAATGCTAAATTATCGATG
CAATTTTTAACAAGTTTGAGTTCAGGGTCTGATAAATAAAATGATTTACTCAATTAATTA
AAGACTCAAACAGCTAAGAATATTCTATTAGAAGAGTTTAACTAATTTGCAATAGAAGTA
AAAATACTTGCTTGTAATCCTATTCTAGAAGCTTTTGGTAATGCTAAAACAGTAAGAAAT
AATAATTCCTCTAGATTTGGTAAATACGTAAAAATCTACATAGATAAAACATCTTAAAAG
ATAAATGGAGCCTCCATTGATAGCTACTTACTCGAAAAGAGCAGAATACCTTGTCCAGGA
AAGGGAGAGAGAAATTATCACATTTTTTACCACATGCTAAAAGGAAATCAAGAACTATCT
AATTTGAGATTGAGTTAGTTCAAAAATTTATCTGATTTTGATTATCTAAAGAAAAGTGAC
TGCTTTGAGGTTGAGAACATTTAAGATGCTAAACTCTATTTGGAAGTAAAGAAGTCCTTC
AGATAAATGAATTTCTCTAACTAAGAGTAAGAAGCTATATTTTCTCTAATATCTGCGATA
CTACTGTTAGGCAATGCAAATTTAGACTCATCAAAAGCTAGCGACACTCAGGCTCCAACT
TTTTTGAACATGAGTTTACCGACACATCATAAAGAATTCAAAAATGCCTCTGAGTTACTC
TAAGTTAATCCTAAAGACCTTGAAGAGTCTTTAGTATTTAAGGTAAGGAAAGTTGGAACT
ACAGTAATTAAATCTCCATAAACTGCTGAAGAATGCTTGTCTATGAGAGACAGTCTAAGT
AAAAATCTATATGATAGTCTTTTTAACTTTTTGGTTTGGAAGTTAAATTAAAATTTGTTG
CCACCTTAAGATTTGCTAAATAAATCATTAAGCATAGGCCTTTTAGATATATTTGGTTTT
GAGAGCTTTGATATAAACTCATTTGAGCAGCTTTGCATTAATTTTACCAATGAAAAATTT
TAGTAATTGTATGTTTAATATGTTTTCAAAAGCGAAGAAGAAGATTATAAATAAGAAGGA
ATTTTGGATGTATTTTCTGATTTATAATATTAAGAGAATTAGCTCATTATTGATACAATT
GAAAAAAAACCCAATGGTAAATTCTTATTTTCATATTTTACATTTTGATTTATATTTTAT
TTAAAGGAATCATGGTGCTTTTAGATGAAAATTGCTCATTGGGATCAGGGACGGATGATT
CTTTTTTAAATTAAATTACAAAAAACCACTCTAAAAATCAACTTGTCAGCTTCCCTAAAA
AAGATAAATATTCTTTCAGCCTTAGTCATACAGCAAAACAAGTTGTATATGATGTGCGCG
GATTTAGAGATAAAAATAAAGATGAAGTGAGTACCGAAGTAGAAAAATGTCTTTAAAGTA
GTAAATGTCCAGTTATTGCGAATTTATTATCTTATTAAGGGTCTTAAACTTAGTAGAATA
AAGAAACTTAAAATCTTCAAAATTTTGGAAATAATTTAAATTTTAAAAAAGCTGAAATTA
GTAATCAAATGAACTCAAGTAAAAAGAATGTAAAGTTTCTAGGCTAAAAATTTAGATAAT
CTTTATAGGAATTAATGATAGAATTGAATAATAGCGATGTTCACTTCATAAGATGTATAA
AACCAAACGAAGAAAAGAAAAAGAATTTTTTTAAGTATGATTATGTTTATTAGCAAGTAC
AGTATTTAGGCATACTTGATTCCATTAAAATCCGCAAAGTTGGATATTCTTACAGAATGA
CTTATGAAAACTTTTTCTTAGAATACCAAGAACTGGGATAGAAAACAAAAGGATTAACAT
TGTAGAAGGTTTAGCAATAAAAGTTAGATTTAAAATAATTAATTACAACAGAAATATTTG
AAAAGACCAATTTATTGCAAAATAAATAACTTCCTTAGAAATGTGTAGCATTTGGAAAAA
CAAAAATATTTCTCAAAAATGAAGTTATGAAGATTTTGCATGAAAAAATTTAAGAAATTA
TTTAATAAAGAAAAAAATATGCAAAGCGAATTATTGTCTCAATTTAAAAATATCTGTTTA
GGAAATACTTCCATAAGAATTTAATGAAAATAAAAAATTAATTAATTAAATTGCAATCAT
TTGCTAGAATGGCTATTTAAAGATAAAAATTCCTAAGGAAAAAGAAATCAATATTAAAAA
TGAAGAAGCTTATTAGGCTAAGAATGTTGGGATAAGGAATCTCTGCATTTAGGTTAAACT
ATATCTCATTTGTGTGGGATTTGGTTTGTTTTATGATATTTGATAAAACAAATATTCATA
TTGCATTTTAGTAAATTAAATATTATCGTAACCCAAATAAAACTAAGCCTGTTGTTCAAA
ATTAAACATCTACAATTTAGTAAAATAAATAGTAAAATCAACAAGTAAAATTAAAATAAA
TATTTAAATGTTTATTTAAATTTTTTTATTTTAAAATAGCCTTAAAAAAGCCAAAATTAA
GTTACTTCATCATTTTAAGTAAATAATTAAATGATGCAATAAAAATAAAGTCTTGTAGGC
CAATAAATTTAATCTATTGTAAACGAGCTTAATTTAGGTGAGATATAAATTAATAAAACC
TAACAAGATTTAAAAGACTTTAGAAAATCAAAGATTATACCTTAAGTTAACTTGAATCCA
TCACAGTATTTAATTTTATTTAAATTATTTATTTAATTCGTACAAATTTTAAGAGAAATC
AAAATCTATAAAAAATTTTTTTAGGATTTAAAAATTTGAGCTATGATTAGATGTTAAACA
TTTTCTTATTTTGCATTAAATTGAATTTAAATAAAATCATGCAATTATTAATTTGAAAAT
CAATTTAAATTAAATTAATAATAAAAATTTTAGTGAAATTATTAAGACCTACACCCATAA
AATGGATTGAAAAAATATTTTCACTACTTAAAATATTTGTTTTAATTAAATTTTAAATAA
AAATTAATTAGTAGTAGTAAGAGGGCCAGCAATGCTTGGAGATAAACCCTAATTGCAAGT
AGTAGTTAAAATAAAATTAATAAAGATTTGTAGCTATCTGAATTAGGAGAGTAGAAGCTG
ATAAATATGAAAGAAACAACTGACTAAAAAGAAAAAATTAAATATACTAAACCTCTGATA
TTATAATTTACAGAGTATAACCCTGCTTATTAGTATGCAGAGTTTAATATGGAGAGTGCA
ATAGATTTAGAAGATGTTCCTAATAGTTTAGATTTTGAGGGTGAATTAAATGATTTGATA
AGTGAAGAAATCATTCAATAAATAAAAAAAAATAACTTTTATTCACACCTTTCTTTTATT
CTTGCAAAAAGAACAAAATGGGGAATCACACAAACTTAAGAGAAAATAATGAGGCACTAG
CTTAAACCAATTTCAAATCCACTAACAAATATTGCTGATTTGAAGAATATAATCACCTAT
GAAGACACAAAAGATGCTGTTTAATCAATTAGGAGTATTATTCAATAAAATAATTTATAT
AATGACACATCAACATAGACTTAAAGACCAATTAATTATGAAGATGCTAGAACTGGAAAA
TTAGATAAGTAAGTATCTAAATAAATTACTAACGATTAATCACAAAAATTAGCAACTGTC
TTTTCGAAATATTCTCTGATGAACCCAAGAAAAGCTAGTGTTAGAGACACAAACTCACTT
GAACAAATTGTCCTATAATAAAGAAAACTTACAAAATTAATTTAGTATAAAAAATTTTCT
CCTTCAGAAAAAGCTATTAACATATTTAAAACTCTCTTAAAGTGCACAGGAGAAAGAAAA
TCCCGATATAACAGACACAACAATATCATAAAGCTTCTTACCCTTTGTAACGAAGAGTCA
ATCGACCTAAAAGAAGAAGTAAATTAAAATTTTTTTGTCAAAATACATATTTGATTTTAA
TCTCTTTTTCTTTTTTTTTTAGTGAAAAATAAGAATAAATTAAAAAAAATAAATGCTTTA
TCAATAAATAAAAATTTTATCAGCATTAATTAAGTTTTTAAACTAATATTTTAATCTTTT
ATGATTCAAATAACATTTTTGAAAACCATTTTTTAAATATGCATTTTGGGAAATTTTAAA
TTGATGAATTAAAATATTTTAGGTTTACGTTTAATTATGCAAATAATTAAGTGCAAATGA
TAAAAAGGAGTCAAGAATAAAATATTTAAAGCTGTTTGCTATTATAAGCAGCATACTGCC
AACAACCAGTAGATTTTATTATCCTTTACTTCACTTTTTATATATGAGAAATACAGATAC
TCAAATAGAATAGGATGAGAGAAAATGGTACTAATACTGTTTTCAAAGAATTTATAAAAG
TGAGTAAATACAAAGAGGATGCATCCCAACTGATACTGAAATTGTAATGATTGAGAATAA
GAAACAAATTTTGATTAGAGTTTATCTTCTAAATGAAATCCCAATTACTGTAGGAGTAGA
AAGCTATACTAGTGTGAAGATGCTTAAGCAGGAGCTACTTTAGAAAATAGGTATAACCTA
AAGACATGAATATTATGGCCTTATGGAAGTAAGAAACAATATTAAGAAAAAGAGAAAAGA
AACGAGATTTATAGATGAAAGTGAGAGAGTAATGGATGTGATAGCTTTTTGGGAAAATGA
GTAGTATTTATTTGGATCTCAATTAAATTCTTCTTTCATACATAGCAACTCAAAATAAAA
TGATGAAGGTATTGAGCAATTCAACCTTTAAAATTATTAGGATCTTGAAGGACTTAAAAT
TTACCTTGGAATCAGAATACTTTTTTCATTTTAAGAAAACGATAAAGAAGCAATAAGCGT
TTTCTACACTTAGCTATCTTCAGAAGTACTTGAAGGAAAGTATGCACCTTTGGAGGAAAA
AGATTACTTGAATTTGGCTGCTTTATAACTGTGCATAGATTTTCCAAGAGACGTCATTTT
AAAAGAAATATCTAAAAGATAGAGTATCAATGCAGATAGTGGGTCTCCATAAAGAACATA
GAGTAATTTTTTGAGTGCTACTAGCTAAAGTGAAAGCGGTGCATCACAGCTTAAAAAGCT
TTCTTATTAAGATATTGAACAGATTGATGAATAAGATGAATACGAACAATTCATATAAAA
TAGAAATGAAATTTTAATTGATCCGGTTTTTTACATACCAGCTAAAATGTATTTCTAAAA
AGATATTCAGTAATGGTAACACTTAATACTATAGAATTTGGTTGATAATAGACTTTTAAA
GAAAGAGTACACTCCATCTTAAGCAAAGTTAGCCTACATACTTTATCTTAGTAAGTAAGA
TTTGTTTATGAGTACAATATTTAGAGATGTAAAATACCAAAGAATCAAAATTAAAACACT
AAATGACACACTTTCTTCTAAAGAAAAATATGAGCAAATGATTTAATAAAATTAACAAAT
TCCCATTAAAGACGAGATACTTTTAGCAATAAACCCATCTAATATTCTGATGTGCGATTC
TATAGGTTTAAATAGACCAAAAAGAAGAGTGCAAATTAAAAATATCTAAAAATTTTGCTG
CACTGAGAAGGAAGTTATAGTAATATCTCATGATAATACAAAACATATTTTTGAAACTCC
CCAATACTGTAGAGAAATAGCTTTCTTAATTCGCTCTTACTTGAGAATATTTTATTAAAA
ATAATAGTAACAACAATAATAAGAAAAAAGTCAATGA
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