Identifiers and Description

Gene Model Identifier

TTHERM_00636860

Standard Name

TRM1 (TRNA Methyltransferase 1)

Aliases

PreTt19689 | 91.m00104

Description

TRM1 N2-N2-dimethylguanosine tRNA methyltransferase; N2-N2-dimethylguanosine tRNA methyltransferase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• tRNA (guanine-N2-)-methyltransferase activity (IEA) | GO:0004809
• RNA binding (IEA) | GO:0003723

Biological Process

• tRNA processing (IEA) | GO:0008033

Domains

• ( PF04032 ) RNAse P Rpr2/Rpp21 subunit domain
• ( PF07754 ) Domain of unknown function (DUF1610)
• ( PF02005 ) N2,N2-dimethylguanosine tRNA methyltransferase
• ( TIGR00308 ) N2,N2-dimethylguanosine tRNA methyltransferase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00636860

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_03510.1	9.997093137033517e-262	N2,N2-dimethylguanosine tRNA m ethyltransferase (598 aa)
Oxytricha	Contig10417.0.g41	2.9996277075259347e-88	N2,N2-dimethylguanosine tRNA m ethyltransferase
DictyBase	DDB_G0284575	1.0001267035975107e-72	DDB_G0284575 on chromosome: 4 position 2173651 to 2175465
WormBase	WBGene00006613	2.0007889996237956e-71	locus:trm-1 tRNA (guanine(26 )-N(2))-dimethyltransferase status:Confirmed UniProt:Q23 270 protein_id:CAB00881.1
SGD	YDR120C	6.9972728945133496e-59	TRM1 tRNA methyltransferase; t wo forms of the protein are ma de by alternative translation starts; localizes to both the nucleus and mitochondrion to p roduce the modified base N2,N2 -dimethylguanosine in tRNAs in both compartments
Stentor Coeruleus	SteCoe_11063	3.6251409191435593e-34

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00636860(coding)
ATGTTAAAAAAAATCTTTAGCATAATTGGAAACTAATTAAACAAAAATAAATAAACAGTA
CTTCATAATCAAACTAATATTCAAGCAAAAAGGAGAACTTTTATTTTCGATTTTACAAAA
TATTTTAGAAAAATGGATAGCGAAGTTACAAACCAAATGTAAGTTGAGGAGGTTCCTTAA
TAGATAATTCAAGAAGAATCTAAATAGAATATTTAGTAGTAAATTACCAATTAACCAGTA
GATAATACCTTTATTTAGGAGGGATATGCTAAGATCTAAAAGTCTTACATTGAAAATTCA
GAAGATGGTAAAAAGTTGTTATCAGAAGTGTTCTACAACCCAGTTTAAGTTTTCAATAGA
GACTTAACTGTTTTGGTTATTCATATGTTCAAGGAATACTTAAAGGAAACTAGAAAGGAA
AAATTTGATGGAATAACTATTTTAGATGCTCTTTCTGCTAGTGGTCTTAGAGCAATTAGA
TTTAGCAAAGAACTTAAAGATATTAAGAAAGTCTATGCAAATGATATTTCCGAAGCATCC
CATAAGTTAATGATGGATAATTTCATATTGAACAATTTAGATCTTAGCAAAATTGAAATG
ACTTTAAAGGATGCCGTTTAGTTAATGTATGAATAAAAGTTCAGGAGCTCATCTGGAGAT
AGAAATGCTCGTTTTGATGTAATTGATTTAGATCCATATGGAACTTGTGCTCCATTCCTT
GACTGTGCCATTTAAGGCGCTGTTGGAGAAACATTACTATGCATTACTTCTACTGATTCT
AGAATCCTCTGTGGACCAGATACCTAAAAGTGCTACTATTTATATGGATCATCAAGAGCT
AAAATCGCTGCCTATGAAGAAAATGCAGTTAGAATTATTTTATATACAGCTAATAACATC
GCCAATAGATATGGAAAGTTTATTACACCTTTACTTTGTTACATGAGTGAATTTTATGTT
AGAGTCTTTCTTATAATCAAGCCTGGTAAACTTGAATGTGGAAGATCTTTAGTACGTACT
GGTAATGTTTTTCATTGTGATAACTGTTAGAATTAATACTTCCAAACATTTGGTAAGTAA
TCTAAGGCTAAGCAAAGTGATGCCCAAAAGCACGTTCCTTAAAAATTGAATCTTCCTAGC
AATATTTGCAATTAATGTGGAGAAAGCTTTACCATCAACGGACCTATTTGGACAGACAAA
TTGAATGATTAGGAATTCATCTAAAAAACTATTGATTATCTTAATTCAGATAAATTCGAT
TTACCTTTGGCTACTAAAAAGAAAATTGAAGGAATGTTGCACTCAATTTAGCTTGAGTAA
AAAGCTGGTGTTGATAATATTCCTTTAGGATTTAACTTTGAACACTTATCCAAGATGATG
AAAACTACAGTTCCAAGCAAAAAGAAAATTTTTTCAGCAATTAAAAGTTTAAATTATTCT
ATTGAATAAACATACTTAAATCCTGCTATATACAAAACAAATGCTCCTTCTGAAATAGTT
TTTGATGTTATCAGAAACTGGAAAAGAACCCTATAGCCAAATGATGAAGAATTCTTCAGG
GCATTTGATAAGGAAAGCTCTAATTATGCTATAGTCTCTAAACCAAACATATGCTAGCCC
AACTTCGATTTAGATATTAATGTTGAAAATAAACTACCAAGATGGCTTCCTAATCCAGAG
AAAAATTGGGGACCAGGAAAGAGACCTGCTCAAAAACTTCTAGTTGAAGAAGGATAAAAT
GAAGAAATCTAATAAGAACATTAGGATAATGGAGATGAATTAAAAAAGAAAAACAAAACA
GATTGA

>TTHERM_00636860(protein)
MLKKIFSIIGNQLNKNKQTVLHNQTNIQAKRRTFIFDFTKYFRKMDSEVTNQMQVEEVPQ
QIIQEESKQNIQQQITNQPVDNTFIQEGYAKIQKSYIENSEDGKKLLSEVFYNPVQVFNR
DLTVLVIHMFKEYLKETRKEKFDGITILDALSASGLRAIRFSKELKDIKKVYANDISEAS
HKLMMDNFILNNLDLSKIEMTLKDAVQLMYEQKFRSSSGDRNARFDVIDLDPYGTCAPFL
DCAIQGAVGETLLCITSTDSRILCGPDTQKCYYLYGSSRAKIAAYEENAVRIILYTANNI
ANRYGKFITPLLCYMSEFYVRVFLIIKPGKLECGRSLVRTGNVFHCDNCQNQYFQTFGKQ
SKAKQSDAQKHVPQKLNLPSNICNQCGESFTINGPIWTDKLNDQEFIQKTIDYLNSDKFD
LPLATKKKIEGMLHSIQLEQKAGVDNIPLGFNFEHLSKMMKTTVPSKKKIFSAIKSLNYS
IEQTYLNPAIYKTNAPSEIVFDVIRNWKRTLQPNDEEFFRAFDKESSNYAIVSKPNICQP
NFDLDINVENKLPRWLPNPEKNWGPGKRPAQKLLVEEGQNEEIQQEHQDNGDELKKKNKT
D

>TTHERM_00636860(gene)
ATGTTAAAAAAAATCTTTAGCATAATTGGAAACTAATTAAACAAAAATAAATAAACAGTA
CTTCATAATCAAACTAATATTCAAGCAAAAAGGAGAACTTTTATTTTCGATTTTACAAAA
TATTTTAGAAAAATGGATAGCGAAGTTACAAACCAAATGTAAGTTGAGGAGGTTCCTTAA
TAGATAATTCAAGAAGAATCTAAATAGAATATTTAGTAGTAAATTACCAATTAACCAGTA
GATAATACCTTTATTTAGGAGGGATATGCTAAGATCTAAAAGTCTTACATTGAAAATTCA
GAAGATGGTAAAAAGTTGTTATCAGAAGTGTTCTACAACCCAGTTTAAGTTAATAACATT
AACACAGCAGCATTAAATTCAAAATGAGCTGAGCTAATTTGCTTATTTTTATTAGCTGTT
TATAAATTTTTTATCATCTTACTAAAGACATTTTTAATTATGATCATTAGGTTTTCAATA
GAGACTTAACTGTTTTGGTTATTCATATGTTCAAGGAATACTTAAAGGAAACTAGTAATT
AAATTTTGGAATTATTGAATTAAAGATTCTTAAAATATTAAGATAAAAATATTTTAAATT
AAATTTAGGAAAGGAAAAATTTGATGGAATAACTATTTTAGATGCTCTTTCTGCTAGTGG
TCTTAGAGCAATTAGATTTAGCAAAGAACTTAAAGATATTAAGAAAGTCTATGCAAATGA
TATTTCCGAAGCATCCCATAAGTTAATGATGGATAATTTCATATTGAACAATTTAGATCT
TAGCAAAATTGAAAGTAAAAACATCTTTTACATATTTTTTAACTCATAATATTAAATAAA
ATTGAGGTAGATAAATTCTTATTTTATAAATTATATTTAAGTGACTTTAAAGGATGCCGT
TTAGTTAATGTATGAATAAAAGTTCAGGAGCTCATCTGGAGATAGAAATGCTCGTTTTGA
TGTAATTGATTTAGATCCATATGGAACTTGTGCTCCATTCCTTGACTGTGCCATTTAAGG
CGCTGTTGGAGAAACATTACTATGCATTACTTCTACTGATTCTAGAATCCTCTGTGGACC
AGATACCTAAAAGTGCTACTATTTATATGGATCATCAAGAGCTAAAATCGCTGCCTATGA
AGAAGTAACTTTTAGATATTTTAAGGAAATTTTGAGTTAAATAAATGTATTATTAATTAA
TATAGAATGCAGTTAGAATTATTTTATATACAGCTAATAACATCGCCAATAGATATGGAA
AGTTTATTACACCTTTACTTTGTTACATGAGTGAATTTTATGTTAGAGTCTTTCTTATAA
TCAAGCCTGGTAAACTTGAATGTGGAAGATCTTTAGTACGTACTGGTAATGTTTTTCATT
GTGATAACTGTTAGAATTAATACTTCCAAACATTTGGTAAGTAATCTAAGGCTAAGCAAA
GTGATGCCCAAAAGCACGTTCCTTAAAAATTGAATCTTCCTAGCAATATTTGCAATTAAT
GTGGAGAAAGCTTTACCATCAGTAAATATTTAGCTTTGTATTTATTAAAATATAAAAAGA
ATTAAATTATTTATATTAATTATAAAGACGGACCTATTTGGACAGACAAATTGAATGATT
AGGAATTCATCTAAAAAACTATTGATTATCTTAATTCAGATAAATTCGATTTACCTTTGG
CTACTAAAAAGAAAATTGAAGGAATGTTGCACTCAATTTAGCTTGTAAAAACTAAATAAT
TTTGCAATTTATATAATTTTTATTAATAATTTTATAGGAGTAAAAAGCTGGTGTTGATAA
TATTCCTTTAGGATTTAACTTTGAACACTTATCCAAGATGATGAAAACTACAGTTCCAAG
CAAAAAGAAAATTTTTTCAGCAATTAAAAGTTTAAATTATTCTATTGAATAAACATACTT
AAATCCTGCTATATACAAAACAAATGCTCCTTCTGAAATAGTTTTTGATGTTATCAGAAA
CTGGGTAAAAATATATTTTTTTACTCATTCATTTATTTTATTTATAAGTTTTAGAAAGCT
AAAAAATTAATTAAATATTATAAAACAGAAAAGAACCCTATAGCCAAATGATGAAGAATT
CTTCAGGGCATTTGATAAGGAAAGCTCTAATTATGCTATAGTCTCTAAACCAAACATGTA
TTTGCTTAAATTTTACATATAATTAAAATACTATTTATAATTAAAAAAAATAGATGCTAG
CCCAACTTCGATTTAGATATTAATGTTGAAAATAAACTACCAAGATGGCTTCCTAATCCA
GAGAAAAATTGGGGACCAGGAAAGAGACCTGCTCAAAAGTAATTTTTATATCTTTCTTAT
AAGAGCTTTAACTAATTTTACTATGAATTGTTCTATTAAAAAGACTTCTAGTTGAAGAAG
GATAAAATGAAGAAATCTAATAAGAACATTAGGATAATGGAGATGAATTAAAAAAGAAAA
ACAAAACAGATTGA