Tian M, Mochizuki K, Loidl J (2022) Arrested crossover precursor structures form stable homologous bonds in a Tetrahymena meiotic mutant. PloS one 17(2):e0263691 PUBMED:35171923
Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ): PUBMED:34086947
Nabeel-Shah S, Garg J, Kougnassoukou Tchara PE, Pearlman RE, Lambert JP, Fillingham J (2021) Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. STAR protocols 2(1):100362 PUBMED:33786459
Identifiers and Description
Gene Model Identifier
TTHERM_00854280
Standard Name
TPT1 (tRNA 2'-phosphotransferase 1)
Aliases
PreTt12253 | 151.m00066
Description
TPT1 RNA 2-prime-phosphotransferase Tpt1/KptA family protein; RNA 2'-phosphotransferase- Tpt1 / KptA family protein
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
Gene Ontology Annotations
Molecular Function
transferase activity, transferring phosphorus-containing groups (IEA) | GO:0016772
Biological Process
tRNA splicing, via endonucleolytic cleavage and ligation (IEA) | GO:0006388
TPT1 tRNA 2-phosphotransferase
, catalyzes the final step in
yeast tRNA splicing: the trans
fer of the 2-PO(4) from the sp
lice junction to NAD(+) to for
m ADP-ribose 1-2cyclic phospha
te and nicotinamide
Ref:25303953: Cranert S, Heyse S, Linger BR, Lescasse R, Price C (2014) Tetrahymena Pot2 is a developmentally regulated paralog of Pot1 that localizes to chromosome breakage sites but not to telomeres. Eukaryotic cell 13(12):1519-29
Ref:24297442: Premkumar VL, Cranert S, Linger BR, Morin GB, Minium S, Price C (2014) The 3' overhangs at Tetrahymena thermophila telomeres are packaged by four proteins, Pot1a, Tpt1, Pat1, and Pat2. Eukaryotic cell 13(2):240-5