Identifiers and Description

Gene Model Identifier

TTHERM_00456750

Standard Name

TOP2B (TOPoisomerase )

Aliases

PreTt20305 | 53.m00207 | 3712.m00067

Description

DNA topoisomerase type 2

Genome Browser (Macronucleus)

GBrowse

Genome Browser (Micronucleus)

GBrowse

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( TIGR01059 ) DNA gyrase, B subunit
  • ( TIGR01063 ) DNA gyrase, A subunit
  • ( PF04702 ) Vicilin N terminal region
  • ( TIGR01055 ) DNA topoisomerase IV, B subunit
  • ( TIGR01058 ) DNA topoisomerase IV, B subunit
  • ( TIGR01061 ) DNA topoisomerase IV, A subunit
  • ( TIGR01062 ) DNA topoisomerase IV, A subunit
  • ( PF00521 ) DNA gyrase/topoisomerase IV, A subunit
  • ( PF00204 ) DNA topoisomerase II (N-terminal region)
  • ( TIGR00162 ) conserved hypothetical protein TIGR00162
  • ( PF02518 ) ATPase, histidine kinase-, DNA gyrase

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

TetraMine Data

TTHERM_00456750

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Stentor CoeruleusSteCoe_197540
WormBaseWBGene000107859.997093137033517e-262locus:top-2 Probable DNA top
oisomerase 2 status:Partiall
y_confirmed UniProt:Q23670
protein_id:CAA88867.1
Tetrahymena borealisEI9_13766.19.997093137033517e-262DNA gyrase/topoisomerase IV, A
subunit protein (1604 aa)
DictyBaseDDB_G02704189.997093137033517e-262top2 on chromosome: 1 position
4831688 to 4836353
OxytrichaContig14442.0.g1089.997093137033517e-262DNA gyrase/topoisomerase IV, s
ubunit A
SGDYNL088W9.997093137033517e-262TOP2 Topoisomerase II, relieve
s torsional strain in DNA by c
leaving and re-sealing the pho
sphodiester backbone of both p
ositively and negatively super
coiled DNA; cleaves complement
ary strands; localizes to axia
l cores in meiosis

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences

>TTHERM_00456750(coding)
ATGTCAGTCGAAACAACTTATCAAAAAAAGACACAACTTGAACATATTTTATTGAGACCA
GATACTTACGTAGGTTCCAATGAATACCAAGATGAATAAATGTGGGTTCTAGCAGATGAC
GGATCATCTTTTGAAAACAGACAAATAAAGTATGTCCCAGCTCTTTATAAAATCTTTGAT
GAAATTCTTGTCAACGCAGCTGATAACTATTAGAGAGATAAGAGAATGAAAAGATTAGAT
GTAATTATTGATCAAAAGAACAATTGTATTTCAATCCTAAACGACGGAAAAGGAATTCCT
GTTTAGATTCATAAAGAATATAATATTTATGTTCCAGAACTTATTTTTGGACATCTTTTG
ACTTCTTCAAATTATAATGACGAAGAAAAAAAAGTTGTAGGAGGTAGAAATGGTTTTGGT
GCAAAGCTTACCAATATATTTTCAACTAAGTTTATTGTAGAATCAGCAGACTCTAAAAAC
AAAAAGAAATTTTAAATGACTTGGACAAAAAACATGTCTGAATAATCTGAACCACAAATA
TCAAGTTATACCGAAAGCGACTACACAAAAATCACTTTTTACCCTGACTTAAAGAAATTC
CACATGAAAGAACTAGAAAAGGATATTGTTGACTTGATGAAAAAAAGAGTATATGATATG
GCTGGTGTCATTGGCGGCTCTGTTAAAGTATCATTAAATGGAGAAAGAATTTCAATAAGT
TCATTCTCTGATTATTGCGATTTTTATTTAAAGAACCAAGGTGCAGAAGTAATTAAGGTA
TCAGATAATAAAGGTACCAATAATTAAAGATGGGAAGTTATAGCAAGTTTATCAGAGGGC
TAATTCTAATAAGTTTCATTTGTTAATTCAATTTGCACCTCAAAGGGAGGTACTCATGTT
AACTACATAACTGACTAAATCACTGAAAAATTGATGGAAACTTTGAAAAAAAAGGAGAAA
AGTCTTAACATTAAGTAATTTTAGGTTAAGAGTCATTTATGGATTTTCGTTAATTGCTTG
ATTGAGAATCCCTCTTTCGATACTTAAACTAAAGAAACACTAACTTTAAGATAATAAAGC
TTCGGTTCAACCTGTGAAGTTTCTGAAAAGTTTATCAAAGAACTCTTAAAATCAAATATT
ATTAATCATATCCTCCTTTAAGCTAGAGCTAAAGAGTAAGCAAAGATGGCTAAAACTTTG
TCTGCTAAAAAGCAAAGTAGATTATTAGGAGTTCCTAAGCTGGAAGATGCAAACGATGCA
GGTACAAGAAACGCTGAAAGCTGTACACTAATTATAACAGAAGGTGATTCTGCCAAAGCT
TTAGCTATGAGTGGTATTGAAGTTGTTGGAAGAGATAAATTTGGTGTCTTCCCATTAAAG
GGTAAAATGTTAAATGTAAGAGATTCTACAAGCAAGCAAATTACAGAAAATTTAGAAATC
TAAAATATCATCAAGGTAATGGGTATGAAGCTAAATACAAACTATGATAATGTTAAAAGT
TTGAGATATGGATCAATTATGATTATGGCTGATTAAGATCACGATGGTTCCCATATCAAA
GGTTTATTCATTAACTTTATATAGAATTTTTGGCCCAGCTTGTTCTAAATGGATGGTTTT
CTTAAAGAATTTATTACACCAATCGTGAAAGTTAGAAAAGGTAATTAATCAATAAGCTTC
TTTAGTATTCAAGACTTTAAAAGATGGAAAAGCACATGCCCAAACTAGCATTTATGGAAA
ATTAAGTATTACAAAGGTCTTGGTACTTCAACCGATTAAGAAGCCTAAGAATATTTTGGA
AATATAAACAAGCATGTCATTAGTTTTAAATACAATGGTAAGGATGATGAAGATGCTATT
GATTTGGCTTTTAATAAGAAGAGAGCTGAAGACCGTAAAAAATGGTTAGTTAAATATGAC
CCAGAAGAAAATGTTGACCACTCATAAAAACATTTGACATACAAAGATTTTGTTAATAAG
GAGCTAATTAATTTTTCTAATTCTGATAATGCAAGATCTATTCCCAGCCTTTGTGATGGT
TTAAAGCCTGGTTAAAGAAAAATTCTTTTTGCATGCTTTAAGAGAAACTTGAAGAATGAA
ATTAAAGTAGCTTAGTTATCTGGTTATGTAGCTGAACACTCCGCTTATCACCATGGTGAA
TAATCTTTAGAATCTACCATTGTAGGTATGGCTTAGAGTTTCGTTGGTACAAATAACATC
AATTACCTCATGCCTATAGGTCAATTCGGTTCTCGTAACATGGGAGGAAAGGAAGCTGCA
TCTGCAAGATATATCCATACTTGCTTAAATAAAATTACTCGTTGTGTTTTCCCTGAGCCA
GACGATCATATTCTCTACTACCTTGAAGATGAAGGATAATAGGTAGAACCTATTTATTAC
CTTCCTATCATCCCTACAGCTCTTTTAAATGGTGCTGATGGTATCGGTACAGGTTGGTCT
ACTAGTATTCCTTGCTATAACCCAAGAGAATTAGTTGATTCAATTGAAAAAAGAATGATG
GGAGTTCCCTTTACTGATTTATTGCCATGGTACAAAGGTTTCACTGGTGAAATTTCTAAT
AACGAAAAATCTTAAATTACTGTTAGTGGAAAGTACCATTTAGTAAATGAAACAACAATA
GAAATTACTGAATTACCTATTAAGAAATGGATTAGAGATTATAAGAACTTTTTAGAAGAG
AAATTAGAATCTACTAAAGATAAGGATCCCGAAATTGAAGATATTAAGGAATATCATGCT
GGTAATAGAGTGCATTTTGTAGTTAAAATGAGCGAAAAGCAAATGGAAAAAGTATAAAGG
GAAGGTATTGACAAATACTTCAAATTATAATCAACTATTCCTACTACAAACATGGTTTTA
TTCAATCATGAAGGAAAACTTACTAGATATGCTAATATTTGCGAAATTATGGAAGAGTTT
TATGAAGTTAGATTAAATGCATATAAAAGGAGAAAGGAATATTTGGTCTCTAAAATCGAA
CGTGATTTAGAAATTCTTTCTAATAAAAAAAGATTCATTTTAGCTGTCATAAATGAATCT
ATTAGAGTAAGAAACGCTAAGAGAAAAGACTTGATCAAAGAACTAAGCGTCTAAGGTTAC
GTCTAAATGAAAGATATGCCAAAAATTAAATCAAGTAAGCTTACAAGCTAACTTGAATAA
GAATAAAATTAAGATAGTAATGAAGAAAATTTTGAAACTAATCCTAATGAGATTAATGCT
AAAGAGTATAACTATCTCCTTAGTTTGCCTATGTGGAGCTTGACTTATGAAAAAGTTGAA
GAGATAAAGTAAGAATAAAAAAATAAGTAGGACGAGTTAGACAAGCTTGTTGCTACTGAA
GTTATTGATATTTGGAAAGAAGATCTTAAAAACTTCATTGAATGCCTTGATTAAATTGAG
GAAGAAGAAGATGAAGAAATGCGTAAAAGAATGAAGAAACAAAGCAACTCTAAAGTTAAA
TAAGGCAGTACAGCTAGTTCTAAGTTAAAGAAAAAACCAACCAAGAAGAAATAAGATAGT
GACGATGATGACGATGATGCCATGGATATAGAGGAAGATGGAGATGGATCAGATTTTGAT
ACAGGCAAGAAAAAATAGAAGAAAAAACCTTCATCAGCTCCTTCTTCATAAGCAGGACCT
AAGGGAAAGATCGGTGATTATAAACCTAATTTGTCTTAAGATACAGGAATAAGCAGTAAA
ACAAATAAAAATAATTAAAATACTCTCGGGTTTATCAAATAGTAAGCTCCAATTACTACT
TAAGTTAAGACTCAACCAGAAGTCAAAAAACCAGTAGATCCTTTGCTTGAAACTTTAGAA
AAATATACTTTCAAGAAAGAAAATACTTAAACATAAAAAGAAGAAAATAATACATAAAAT
TCAGTTATATCTTAAATACTTTCATAAAACTATTCTCTATCACTTGAAGAGAGACTTAAA
TTGAGGGCAGGGGAAAACTCATAAAATTTGACTCAATAAACAAATGGATTTTCCTAATAA
GTAAATACATAATAAGACTATAATAACTTGGGCAATAAAGATGAAGAAGAAGAAGATGAC
CTTCTCTTTAACTTCAAAAAAGAAAAGAAAGAGAAATAATCAACTGATATTTTTGATGAA
TTAGATGATCTTGATGCACTTTTTAATGAAAAACGCTAAGGAGCAGACCTCGAAAATGAA
GAAGAGTAGCTGACCAAAAAAAGAGTTCTGAATGAAGGAGAACCAAAAAGTATAGCTTAA
AATAAAAAATAAACAAAAGAAATAAATGATGAAGATCTTGAATATAATTTGTTTAAGGAT
GAAAAGCCAAAGTAAAAAAAGCCTCCTGCTACTGCTGCTTCAAAATCAAAGAAAGTGATA
AATAAAAATGAAGATGATGATGAAGACTTTAATGATGATTTATCAGAAGATGAAAAACCA
AAGAAGAAAAGGTCCAATTAAACTTAATCAAAAACCAAAAAATAGAAAAATGAAAGTGAA
GATGAAGATTTTAATAGCAAAGAATCTGATGAAAAACCTAAATAAAGAAAATCTAATTCT
AACTCATAAAAAGCAAGGAAACCTAAGAAAATGAGTGATGATGAGGGAGAAGAAGATGAT
GATTTTATCATACCTGATGAGGATTCTGATGAAGAAAAACCTAAGAAGAGAAAGAGTAAT
GCAACAAAACCTAAAAATAATAAAGAAGATAAAGATAATCAAAAGTCTAAAAAAAATAGA
ACCGATTCACCAAAACTTAAAATAACAAATTCAGAAGATGAAGATGTTGCTGAATTAAAG
CAAAATGAAGTTTTATAAACCAGAACAAGAGGTAAAAGAAACCCAATTCCTCGTAAAATG
ATCATTGATAATTCTGATGAAGATTTCAGTGAAGAGGAAGAATTTGGAAATAGCAAAAAG
AAATCAGTAAATAGTAAAAGCCAAAAAAAATAAAAAGACGATGAATCATCGGATGAATGC
TATTTCTGA


>TTHERM_00456750(protein)
MSVETTYQKKTQLEHILLRPDTYVGSNEYQDEQMWVLADDGSSFENRQIKYVPALYKIFD
EILVNAADNYQRDKRMKRLDVIIDQKNNCISILNDGKGIPVQIHKEYNIYVPELIFGHLL
TSSNYNDEEKKVVGGRNGFGAKLTNIFSTKFIVESADSKNKKKFQMTWTKNMSEQSEPQI
SSYTESDYTKITFYPDLKKFHMKELEKDIVDLMKKRVYDMAGVIGGSVKVSLNGERISIS
SFSDYCDFYLKNQGAEVIKVSDNKGTNNQRWEVIASLSEGQFQQVSFVNSICTSKGGTHV
NYITDQITEKLMETLKKKEKSLNIKQFQVKSHLWIFVNCLIENPSFDTQTKETLTLRQQS
FGSTCEVSEKFIKELLKSNIINHILLQARAKEQAKMAKTLSAKKQSRLLGVPKLEDANDA
GTRNAESCTLIITEGDSAKALAMSGIEVVGRDKFGVFPLKGKMLNVRDSTSKQITENLEI
QNIIKVMGMKLNTNYDNVKSLRYGSIMIMADQDHDGSHIKGLFINFIQNFWPSLFQMDGF
LKEFITPIVKVRKGNQSISFFSIQDFKRWKSTCPNQHLWKIKYYKGLGTSTDQEAQEYFG
NINKHVISFKYNGKDDEDAIDLAFNKKRAEDRKKWLVKYDPEENVDHSQKHLTYKDFVNK
ELINFSNSDNARSIPSLCDGLKPGQRKILFACFKRNLKNEIKVAQLSGYVAEHSAYHHGE
QSLESTIVGMAQSFVGTNNINYLMPIGQFGSRNMGGKEAASARYIHTCLNKITRCVFPEP
DDHILYYLEDEGQQVEPIYYLPIIPTALLNGADGIGTGWSTSIPCYNPRELVDSIEKRMM
GVPFTDLLPWYKGFTGEISNNEKSQITVSGKYHLVNETTIEITELPIKKWIRDYKNFLEE
KLESTKDKDPEIEDIKEYHAGNRVHFVVKMSEKQMEKVQREGIDKYFKLQSTIPTTNMVL
FNHEGKLTRYANICEIMEEFYEVRLNAYKRRKEYLVSKIERDLEILSNKKRFILAVINES
IRVRNAKRKDLIKELSVQGYVQMKDMPKIKSSKLTSQLEQEQNQDSNEENFETNPNEINA
KEYNYLLSLPMWSLTYEKVEEIKQEQKNKQDELDKLVATEVIDIWKEDLKNFIECLDQIE
EEEDEEMRKRMKKQSNSKVKQGSTASSKLKKKPTKKKQDSDDDDDDAMDIEEDGDGSDFD
TGKKKQKKKPSSAPSSQAGPKGKIGDYKPNLSQDTGISSKTNKNNQNTLGFIKQQAPITT
QVKTQPEVKKPVDPLLETLEKYTFKKENTQTQKEENNTQNSVISQILSQNYSLSLEERLK
LRAGENSQNLTQQTNGFSQQVNTQQDYNNLGNKDEEEEDDLLFNFKKEKKEKQSTDIFDE
LDDLDALFNEKRQGADLENEEEQLTKKRVLNEGEPKSIAQNKKQTKEINDEDLEYNLFKD
EKPKQKKPPATAASKSKKVINKNEDDDEDFNDDLSEDEKPKKKRSNQTQSKTKKQKNESE
DEDFNSKESDEKPKQRKSNSNSQKARKPKKMSDDEGEEDDDFIIPDEDSDEEKPKKRKSN
ATKPKNNKEDKDNQKSKKNRTDSPKLKITNSEDEDVAELKQNEVLQTRTRGKRNPIPRKM
IIDNSDEDFSEEEEFGNSKKKSVNSKSQKKQKDDESSDECYF


>TTHERM_00456750(gene)
ATGTCAGTCGAAACAACTTATCAAAAAAAGACACAACTTGAACATATTTTATTGAGACCA
GATACTTACGTAGGTTCCAATGAATACCAAGATGAATAAATGTGGGTTCTAGCAGATGAC
GGATCATCTTTTGAAAACAGACAAATAAAGTATGTCCCAGCTCTTTATAAAATCTTTGAT
GAAATTCTTGTCAACGCAGCTGATAACTATTAGGTAAATACCAGCTTAAAAAAACATTTT
TTTATTTTTTTAAGTCTGATCTGATGATAGATAGAAAACAAACTAACACATTTTAATTTT
ATAAATAGAGAGATAAGAGAATGAAAAGATTAGATGTAATTATTGATCAAAAGAACAATT
GTATTTCAATCCTAAACGACGGAAAAGGAATTCCTGTTTAGATTCATAAAGAATATAATA
TTTATGTTCCAGAACTTATTTTTGGACATCTTTTGACTTCTTCAAATTATAATGACGAAG
AAAAAAAAGTTGTAGGAGGTAGAAATGGTTTTGGTGCAAAGCTTACCAATATATTTTCAA
CTAAGTTTATTGTAGAATCAGCAGACTCTAAAAACAAAAAGTAAAGTTATTTGTTATAAA
AATAAATAGGAGGAGTTTAAATTCAAATTACTTTTAATTAGGAAATTTTAAATGACTTGG
ACAAAAAACATGTCTGAATAATCTGAACCACAAATATCAAGTTATACCGAAAGCGACTAC
ACAAAAATCACTTTTTACCCTGACTTAAAGAAATTCCACATGAAAGAACTAGAAAAGGTA
AAATGTGTTTTTTAATAAGAAATTATCCACTTTTAGCAAAATAAATTAACCTTTTGTTTT
AAATAATCTTTCAAATAATTAATAGGATATTGTTGACTTGATGAAAAAAAGAGTATATGA
TATGGCTGGTGTCATTGGCGGCTCTGTTAAAGTATCATTAAATGGAGAAAGAATTTCAAT
AAGTTCATTCTCTGATTATTGCGATTTTTATTTAAAGAACCAAGGTGCAGAAGTAATTAA
GGTAAATATTATTTATTATATAAGGTGAAGGCATTTAGATAAAATCTATTTCTAACAAAC
AAAAGGTATCAGATAATAAAGGTACCAATAATTAAAGATGGGAAGTTATAGCAAGTTTAT
CAGAGGGCTAATTCTAATAAGTAATTAAAAAATAAATGAAAAAAATATCTAATTTTATTT
TATTTTTTTTAAAAGGTTTCATTTGTTAATTCAATTTGCACCTCAAAGGGAGGTACTCAT
GTTAACTACATAACTGACTAAATCACTGAAAAATTGATGGAAACTTTGAAAAAAAAGGAG
AAAAGTCTTAACATTAAGTAATTTTAGGTTAAGAGTCATTTATGGATTTTCGTTAATTGC
TTGATTGAGAATCCCTCTTTCGATACTTAAACTAAAGAAACACTAACTTTAAGATAATAA
AGCTTCGGTTCAACCTGTGAAGTTTCTGAAAAGTTTATCAAAGAACTCTTAAAATCAAAT
ATTATTAATCATATCCTCCTTTAAGCTAGAGTAAACATTTATTTTCAAATTTTTCTTGAA
TTAATTTACCAATTTATTTCTAGGCTAAAGAGTAAGCAAAGATGGCTAAAACTTTGTCTG
CTAAAAAGCAAAGTAGATTATTAGGAGTTCCTAAGCTGGAAGATGCAAACGATGCAGGTA
AATTATTAATTAATTCAAATTTATAACTTTTCTAAAAATAAATATAGGTACAAGAAACGC
TGAAAGCTGTACACTAATTATAACAGAAGGTGATTCTGCCAAAGCTTTAGCTATGAGTGG
TATTGAAGTTGTTGGAAGAGATAAATTTGGTGTCTTCCCATTAAAGGGTAAAATGTTAAA
TGTAAGAGATTCTACAAGCAAGCAAATTACAGAAAATTTAGAAATCTAAAATATCATCAA
GGTAATGGGTATGAAGCTAAATACAAACTATGATAATGTTAAAAGTTTGAGATATGGATC
AATTATGATTATGGCTGATTAAGATCACGATGGTTCCCATATCAAAGGTTTATTCATTAA
CTTTATATAGAATTTTTGGCCCAGCTTGTTCTAAATGGATGGTTTTCTTAAAGAATTTAT
TACACCAATCGTGAAAGTTAGAAAAGGTAATTAATCAATAAGCTTCTTTAGTATTCAAGA
CTTTAAAAGATGGAAAAGCACATGCCCAAACTAGCATTTATGGAAAATTAAGTATTACAA
AGGTCTTGGTACTTCAACCGATTAAGAAGCCTAAGAATATTTTGGAAATATAAACAAGCA
TGTCATTAGTTTTAAATACAATGGTAAGGATGATGAAGATGCTATTGATTTGGCTTTTAA
TAAGAAGAGAGCTGAAGACCGTAAAAAATGGTTAGTTAAATATGACCCAGAAGAAAATGT
TGACCACTCATAAAAACATTTGACATACAAAGATTTTGTTAATAAGGAGCTAATTAATTT
TTCTAATTCTGATAATGCAAGGTAAATAAATTATTAAACAAATTATCATATTGACTTATA
ATTTTTTAATTTTAAAAATAGATCTATTCCCAGCCTTTGTGATGGTTTAAAGCCTGGTTA
AAGAAAAATTCTTTTTGCATGCTTTAAGAGAAACTTGAAGAATGAAATTAAAGTAGCTTA
GTTATCTGGTTATGTAGCTGAACACTCCGCTTATCACCATGGTGAATAATCTTTAGAATC
TACCATTGTAGGTATGGCTTAGAGTTTCGTTGGTACAAATAACATCAATTACCTCATGCC
TATAGGTCAATTCGGTTCTCGTAACATGGGAGGAAAGGTATTAATTTTATTTTCAAAAAC
TTTTTCTTAAAGTTATTATAAAATATAGGAAGCTGCATCTGCAAGATATATCCATACTTG
CTTAAATAAAATTACTCGTTGTGTTTTCCCTGAGCCAGACGATCATATTCTCTACTACCT
TGAAGATGAAGGATAATAGGTAGAACCTATTTATTACCTTCCTATCATCCCTACAGCTCT
TTTAAATGGTATTAAAAAAAATAAAATTCAAATTAAATACTAACTCAATTTTATAAAAGG
TGCTGATGGTATCGGTACAGGTTGGTCTACTAGTATTCCTTGCTATAACCCAAGAGAATT
AGTTGATTCAATTGAAAAAAGAATGATGGGAGTTCCCTTTACTGATTTATTGCCATGGTA
CAAAGTAAGATAAAAATTTACTAATAAAATTTTCTAAAAAATTGAAAATTATTTATTTAC
ACAAACAAGGGTTTCACTGGTGAAATTTCTAATAACGAAAAATCTTAAATTACTGTTAGT
GGAAAGTACCATTTAGTAAATGAAACAACAATAGAAATTACTGAATTACCTATTAAGAAA
TGGATTAGAGATTATAAGAACTTTTTAGAAGAGAAATTAGAATCTACTAAAGATAAGGAT
CCCGAAATTGAAGATATTAAGGAATATCATGCTGGTAATAGAGTGCATTTTGTAGTTAAA
ATGAGCGAAAAGCAAATGGAAAAAGTAATTAATATATGATGAAAAACAAACAAACTAAAA
ATTAATTTTATTAAATTCAAGGTATAAAGGGAAGGTATTGACAAATACTTCAAATTATAA
TCAACTATTCCTACTACAAACATGGTTTTATTCAATCATGAAGGAAAACTTACTAGATAT
GCTAATATTTGCGAAATTATGGAAGAGTTTTATGAAGTTAGATTAAATGCATATAAAAGG
AGAAAGGAATATTTGGTCTCTAAAATCGAACGTGATTTAGAAATTCTTTCTAATAAAAAA
AGATTCATTTTAGCTGTCATAAATGAATCTATTAGAGTAAGAAACGCTAAGAGAAAAGAC
TTGATCAAAGAACTAAGCGTCTAAGGTTACGTCTAAATGAAAGATATGCCAAAAATTAAA
TCAAGTAAGCTTACAAGCTAACTTGAATAAGAATAAAATTAAGATAGTAATGAAGAAAAT
TTTGAAACTAATCCTAATGAGATTAATGCTAAAGAGTATAACTATCTCCTTAGTTTGCCT
ATGTGGAGCTTGACTTATGAAAAAGTTGAAGAGATAAAGTAAGAATAAAAAAATAAGTAG
GACGAGTTAGACAAGCTTGTTGCTACTGAAGTTATTGATATTTGGAAAGAAGATCTTAAA
AACTTCATTGAATGCCTTGATTAAATTGAGGAAGAAGAAGATGAAGAAATGCGTAAAAGA
ATGAAGAAACAAAGCAACTCTAAAGGTAATTTAAATTTTTAATTCAATATAAATAGTTTT
AAAATGCTTTTTAATATGAAAGTTAAATAAGGCAGTACAGCTAGTTCTAAGTTAAAGAAA
AAACCAACCAAGAAGAAATAAGATAGTGACGATGATGACGATGATGCCATGGATATAGAG
GAAGATGGAGATGGATCAGATTTTGATACAGGCAAGAAAAAATAGAAGAAAAAACCTTCA
TCAGCTCCTTCTTCATAAGCAGGACCTAAGGGAAAGATCGGTGATTATAAACCTAATTTG
TCTTAAGATACAGGAATAAGCAGTAAAACAAATAAAAATAATTAAAATACTCTCGGGTTT
ATCAAATAGTAAGCTCCAATTACTACTTAAGTTAAGACTCAACCAGAAGTCAAAAAACCA
GTAGATCCTTTGCTTGAAACTTTAGAAAAATATACTTTCAAGAAAGAAAATACTTAAACA
TAAAAAGAAGAAAATAATACATAAAATTCAGTTATATCTTAAATACTTTCATAAAACTAT
TCTCTATCACTTGAAGAGAGACTTAAATTGAGGGCAGGTAAAAAATTACAAAAAATATTT
TATTTTTACATTATTCATAATAAAAAATAGGGGAAAACTCATAAAATTTGACTCAATAAA
CAAATGGATTTTCCTAATAAGTAAATACATAATAAGACTATAATAACTTGGGCAATAAAG
ATGAAGAAGAAGAAGATGACCTTCTCTTTAACTTCAAAAAAGAAAAGAAAGAGAAATAAT
CAACTGATATTTTTGATGAATTAGATGATCTTGATGCACTTTTTAATGAAAAACGCTAAG
GAGCAGACCTCGAAAATGAAGAAGAGTAGCTGACCAAAAAAAGAGTTCTGAATGAAGGAG
AACCAAAAAGTATAGCTTAAAATAAAAAATAAACAAAAGAAATAAATGATGAAGATCTTG
AATATAATTTGTTTAAGGATGAAAAGCCAAAGTAAAAAAAGCCTCCTGCTACTGCTGCTT
CAAAATCAAAGAAAGTGATAAATAAAAATGAAGATGATGATGAAGACTTTAATGATGATT
TATCAGAAGATGAAAAACCAAAGAAGAAAAGGTCCAATTAAACTTAATCAAAAACCAAAA
AATAGAAAAATGAAAGTGAAGATGAAGATTTTAATAGCAAAGAATCTGATGAAAAACCTA
AATAAAGAAAATCTAATTCTAACTCATAAAAAGCAAGGAAACCTAAGAAAATGAGTGATG
ATGAGGGAGAAGAAGATGATGATTTTATCATACCTGATGAGGATTCTGATGAAGAAAAAC
CTAAGAAGAGAAAGAGTAATGCAACAAAACCTAAAAATAATAAAGAAGATAAAGATAATC
AAAAGTCTAAAAAAAATAGAACCGATTCACCAAAACTTAAAATAACAAATTCAGAAGATG
AAGATGTTGCTGAATTAAAGCAAAATGAAGTTTTATAAACCAGAACAAGAGGTAAAAGAA
ACCCAATTCCTCGTAAAATGATCATTGATAATTCTGATGAAGATTTCAGTGAAGAGGAAG
AATTTGGAAATAGCAAAAAGAAATCAGTAAATAGTAAAAGCCAAAAAAAATAAAAAGACG
ATGAATCATCGGATGAATGCTATTTCTGA