Identifiers and Description

Gene Model Identifier

TTHERM_01018420

Standard Name

THD8 (Tetrahymena histone deacetylase 8)

Aliases

PreTt27759 | 199.m00052

Description

Sir2-like histone deacetylase

Genome Browser (Macronucleus)

GBrowse

Genome Browser (Micronucleus)

GBrowse

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00098 ) Zinc knuckle
  • ( PF02146 ) transcriptional regulator, Sir2 family

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

TetraMine Data

TTHERM_01018420

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_01121.19.997093137033517e-262transcriptional regulator, Sir
2 family protein (386 aa)
OxytrichaContig19063.0.g744.999450098932641e-139Sir2 family
Stentor CoeruleusSteCoe_105972.8946403116483003e-63
WormBaseWBGene000048033.0000451088882257e-25locus:sir-2.4 NAD-dependent
protein deacetylase sir-2.4
status:Confirmed UniProt:Q95
Q89 protein_id:CCD61225.1
DictyBaseDDB_G02839178.997498379799854e-17sir2A on chromosome: 4 positio
n 1272110 to 1273864
SGDYPL015C0.0000000000000030004923591262316HST2 Cytoplasmic member of the
silencing information regulat
or 2 (Sir2) family of NAD(+)-d
ependent protein deacetylases;
modulates nucleolar (rDNA) an
d telomeric silencing; possess
es NAD(+)-dependent histone de
acetylase activity in vitro

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:18178773: Smith JJ, Torigoe SE, Maxson J, Fish LC, Wiley EA (2008) A class II histone deacetylase acts on newly synthesized histones in Tetrahymena. Eukaryotic cell 7(3):471-82
  2. Ref:SUPR000180
  3. Ref:SUPR000158

Sequences

>TTHERM_01018420(coding)
ATGAATACAGCTCATAAAACAGACGATGAAAAAAAGGAATTCTTTGATTCACCTAAAGAA
TTAGAAGAAAAAGTAAATATTTTAGTTGATATGATAAAACGTTCTGAGCACTTTGTTGCT
TTTACAGGTGCAGGTATTTCTACTTCTACTGGAATTCCAGATTTTAGAAGTGGTATCAAT
ACAGTACTTCCAACTGGTCCAGGTGCATGGGAAAAATTAGCTTAAAAGACAGGCAGCTCT
AAAAGTAATGTAAAAGTAAGCATGTCTAAGGCAATACCATCTCCTACTCATATGTCTCTT
GTTGAATTACAGAGATAAGGATATCTTAAATTTTTGATAAGTTAGAATGTAGATGGTTTA
CACAGAAGAAGTGGATTTTCTACTTACCACTTAGCCGAATTGCATGGCAACACAAATCTA
GAAAAATGCTAGAAGTGTGGCAAAGAATACATGAGAGATTTTAGAGTCAGAACAGCCCAA
TAAGTACATGATCATAAAACTGGTAGAAAGTGTGATAATTAATAATGTAACGGAGATCTA
TATGACTCTATTATAAATTTTGGTGAAAACCTCCCTGAAAAAGACTAAGATGATGGATTC
GTTCATTCTTAGTTGGCTGATTTGCATTTAGTTTTAGGAAGCAGTTTAAGAGTAACTCCT
GCAGCTGATATGCCTGAAACTACAGCAAAATTAGGAAAAAATTTAGTTATTGTTAATTTG
TAAAAGACTCCTCTTGATTCTTTAGCTACTCTCAGAATAAATGCCATGTGTGATGATGTT
ATGAAAATGGTTATGAAAAAGCTTAAAATAGAAATCCCAGAATTTATCTTAGAAAGAAGG
ATAGTCCTTTAAAAGGGAGATAAAAACAGTTTACTTGTTTCTGCAGAAGATTCAAATGAA
AGTCCTTATGAAATATATAAAAAAGTTACAATTGAATATGGAAAAGCAAACGAAGCTAAA
TAAAAAGCTCCTTTCAATTTCACCCCCAAGCAAAACCAATTCACAGTGAGTTTAGGTTTC
TATGAACATTATGGAGAGTAAGAATTCAAATTAGATGTTGATATGATAGCTTTACCACTC
AATAAAAAAGTGGTTTACTAAATATAATATTAAGTTAGTCTCTAAAAATGGATAAGCTGC
AAACAAATATGA


>TTHERM_01018420(protein)
MNTAHKTDDEKKEFFDSPKELEEKVNILVDMIKRSEHFVAFTGAGISTSTGIPDFRSGIN
TVLPTGPGAWEKLAQKTGSSKSNVKVSMSKAIPSPTHMSLVELQRQGYLKFLISQNVDGL
HRRSGFSTYHLAELHGNTNLEKCQKCGKEYMRDFRVRTAQQVHDHKTGRKCDNQQCNGDL
YDSIINFGENLPEKDQDDGFVHSQLADLHLVLGSSLRVTPAADMPETTAKLGKNLVIVNL
QKTPLDSLATLRINAMCDDVMKMVMKKLKIEIPEFILERRIVLQKGDKNSLLVSAEDSNE
SPYEIYKKVTIEYGKANEAKQKAPFNFTPKQNQFTVSLGFYEHYGEQEFKLDVDMIALPL
NKKVVYQIQYQVSLQKWISCKQI


>TTHERM_01018420(gene)
ATGAATACAGCTCATAAAACAGACGATGAAAAAAAGGAATTCTTTGATTCACCTAAAGAA
TTAGAAGAAAAAGTAAATATTTTAGTTGATATGATAAAACGTTCTGAGCACTTTGTTGCT
TTTACAGGTGCAGGTATTTCTACTTCTACTGGAATTCCAGATTTTAGAAGTGGTATCAAT
ACAGTACTTCCAACTGGTCCAGGTGCATGGGAAAAATTAGCTTAAAAGACAGGCAGCTCT
AAAAGTAATGTAAAAGTAAGCATGTCTAAGGCAATACCATCTCCTACTCATATGTCTCTT
GTTGAATTACAGAGATAAGGATATCTTAAATTTTTGATAAGTTAGAATGTAGATGGTTTA
CACAGAAGAAGTGGATTTTCTACTTACCACTTAGCCGAATTGCATGGCAACACAAATCTA
GAAAAATGCTAGAAGTGTGGCAAAGAATACATGAGAGATTTTAGAGTCAGAACAGCCCAA
TAAGTACATGATCATAAAACTGGTAGAAAGTGTGATAATTAATAATGTAACGGAGATCTA
TATGACTCTATTATAAATTTTGGTGAAAACCTCCCTGAAAAAGACTAAGATGATGGATTC
GTTCATTCTTAGTTGGCTGATTTGCATTTAGTTTTAGGAAGCAGTTTAAGAGTAACTCCT
GCAGCTGATATGCCTGAAACTACAGCAAAATTAGGAAAAAATTTAGTTATTGTTAATTTG
TAAAAGACTCCTCTTGATTCTTTAGCTACTCTCAGAATAAATGCCATGTGTGATGATGTT
ATGAAAATGGTTATGAAAAAGCTTAAAATAGAAATCCCAGAATTTATCTTAGAAAGAAGG
ATAGTCCTTTAAAAGGGAGATAAAAACAGTTTACTTGTTTCTGCAGAAGATTCAAATGAA
AGTCCTTATGAAATATATAAAAAAGTTACAATTGAATATGGAAAAGCAAACGAAGCTAAA
TAAAAAGCTCCTTTCAATTTCACCCCCAAGCAAAACCAATTCACAGTGAGTTTAGGTTTC
TATGAACATTATGGAGAGTAAGAATTCAAATTAGATGTTGATATGATAGCTTTACCACTC
AATAAAAAAGTGGTTTACTAAATATAATATTAAGTTAGTCTCTAAAAATGGATAAGCTGC
AAACAAATATGA