Identifiers and Description

Gene Model Identifier

TTHERM_00663840

Standard Name

THD3 (Tetrahymena histone deacetylase 3)

Aliases

PreTt23831 | 98.m00174 | 3736.m00072 | THD3

Description

THD3 class I histone deacetylase family protein; Histone deacetylase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00850 ) Histone deacetylase family

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10%

TetraMine Data

TTHERM_00663840

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17202.1	9.997093137033517e-262	histone deacetylase (473 aa)
DictyBase	DDB_G0268024	2.000851114308011e-136	hdaA on chromosome: 1 position 1320084 to 1322172
WormBase	WBGene00001834	2.9988601762256104e-132	locus:hda-1 Histone deacetyl ase 1 status:Confirmed Uni Prot:O17695 protein_id:CAB03 984.1
SGD	YNL330C	3.999751664085691e-132	RPD3 Histone deacetylase; regu lates transcription, silencing , and other processes by influ encing chromatin remodeling; f orms at least two different co mplexes which have distinct fu nctions and members
Oxytricha	Contig1866.0.g68	5.0014192254601655e-126	Histone deacetylase domain
Stentor Coeruleus	SteCoe_31554	1.1677812485237086e-60

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18178773: Smith JJ, Torigoe SE, Maxson J, Fish LC, Wiley EA (2008) A class II histone deacetylase acts on newly synthesized histones in Tetrahymena. Eukaryotic cell 7(3):471-82
2. Ref:SUPR000083

Sequences

>TTHERM_00663840(coding)
ATGGAAACAAAAAAAAGAGTAGCTTATTTTTACAATAACGAAATAGGTAACTACAACTAT
GGAAAGTTGCATTTAATGAACCCAAAAAGAATTTCAATGACTCATTCCTTGATTGTAGGT
TATGGTGTCTATAAAGATCTTGACGTATACACAACAAGAGAAGCCACCAAAGAAGAGATA
ATGCAGTTTCATGATTAGGATTATGTTGAGTACCTTTCTAACTATGTATCGAGTACTAAA
ATAGATTTTCTAAGAAAGAATGGATGCACTGCTCCTATCATAGATGAGGAAGCTAAAAAT
GATGTAGAAAAAAAGAGATAATATGGCATAGATGTTCAAGCTGATTGTCCTGGCTTTGAT
GGTGTCTATACCTTTAGCCAACTTTCAACAGGTGGTTCGATTGATGCAGCTCACTTAATT
ATAAATAATGCTGCAGATGTAGCTATTAACTGGGGTGGTGGATTGCATCATGCTAAGAAG
GGAGAAGCTTATGGCTTCTGTTATGTTAATGATATAGTAATATGCATTTTGGAGCTTTTA
AAAGTATTTCCTCGTGTGCTTTACATAGATATAGATGTACACCATGGAGATGGCGTAGAA
GAGGCTTTCTTTACTACAAATAGAGTAATGACAGTTAGTTTTCATGAATTTGGAGAAGAT
TTCTTTCCTGGAACAGGTGGCCTCAACAGTAGTGGAGAAGGATTGGGCAAAAATTATGCT
GTGAATGTACCACTTAGACCTGGTATGGATGATGAAAGTTATAAATAACTATTTAAAAAT
GTAATGAATAAAGTAATGGAAGTGTTTAGACCTGACGTAGTTGTATTCTAAACTGGAGCT
GATAGTTTAGCTAATGACAAAATTGGGCATTTTAATTTATCTATTAGAGGACATGGCGAA
TGCTTGACTTACATGCTAAGGTTTAATGTTCCTGTAGTAGTTTTAGGAGGAGGTGGATAT
ACTATTTAAAATGTAAGTCGTTGCTGGGCATATGAAACAGGATTACTTGTTAAAAAAAAT
TTAAATGGACCTATACCTGTTGATGATCCCTTTTTCCATTTATATGAAAAATAGAATATG
CTTCACGTTCCAATTTAGCAAGTAGAAAATAAGAATAGTAAAGAAGATTTAAATAAAATA
TAAGAAGAGGTCTTTAAGCAACTAAAAGAAGTAGATGCTGCCCCATCAATACCTTTTCAT
AATGTTCCCAAAGCATTCTAGTATGATGACGATGAATATTTCGAGGAAAATGAATAAGAT
TAACATCATGATTTTTCTGGAAATACTTATAATTTCAATAAGCTTAATGACTATATAAAC
GGATATTAAACAATGGAGGTCGAATAAAATGAAGAAGTTGGAGTATATAGAAAACAACCT
CTATTAATAGAAAAGAATAGTAGTAGATTTAATCATATTTGA

>TTHERM_00663840(protein)
METKKRVAYFYNNEIGNYNYGKLHLMNPKRISMTHSLIVGYGVYKDLDVYTTREATKEEI
MQFHDQDYVEYLSNYVSSTKIDFLRKNGCTAPIIDEEAKNDVEKKRQYGIDVQADCPGFD
GVYTFSQLSTGGSIDAAHLIINNAADVAINWGGGLHHAKKGEAYGFCYVNDIVICILELL
KVFPRVLYIDIDVHHGDGVEEAFFTTNRVMTVSFHEFGEDFFPGTGGLNSSGEGLGKNYA
VNVPLRPGMDDESYKQLFKNVMNKVMEVFRPDVVVFQTGADSLANDKIGHFNLSIRGHGE
CLTYMLRFNVPVVVLGGGGYTIQNVSRCWAYETGLLVKKNLNGPIPVDDPFFHLYEKQNM
LHVPIQQVENKNSKEDLNKIQEEVFKQLKEVDAAPSIPFHNVPKAFQYDDDEYFEENEQD
QHHDFSGNTYNFNKLNDYINGYQTMEVEQNEEVGVYRKQPLLIEKNSSRFNHI

>TTHERM_00663840(gene)
ATGGAAACAAAAAAAAGAGTAGCTTATTTTTACAATAACGAAATAGGTAACTACAACTAT
GGAAAGTTGCATTTAATGAACCCAAAAAGAATTTCAATGACTCATTCCTTGATTGTAGGT
TATGGTGTCTATAAAGATCTTGACGTATACACAACAAGAGAAGCCACCAAAGAAGAGATA
ATGCAGTTTCATGATTAGGATTATGTTGAGTACCTTTCTAACTATGTATCGAGTACTAAA
ATAGATTTTCTAAGAAAGAATGGATGCACTGCTCCTATCATAGATGAGGAAGCTAAAAAT
GATGTAGAAAAAAAGAGATAATATGGCATAGATGTTCAAGCTGATTGTCCTGGCTTTGAT
GGTGTCTATACCTTTAGCCAACTTTCAACAGGTAATAAATTATATTTCCATTTTGAACAA
GAATTTGAGTTAGTTGGATTTACAGTTTTCAAAATATATACTAGAAAAAATTTACTTGCT
TAAATCTTCTCCTTCTATTTAAAGAATTTGAGTAGAAGAAAGTAATAAATATTCAATAAA
TAATTAATTATTATCCTAGAAAATGGTGAAAAATAATAGTTAAACACAATTTCAAAAAAA
ATTATTTTTAACCCAAATTTATATTTTAAAATATTTAAAAAATATTCATTTTAGTAAAAA
TAAAATTTAAATTTAATATCTTAATATTTTTTTTCTTTAAACCATAATTAGGTGGTTCGA
TTGATGCAGCTCACTTAATTATAAATAATGCTGCAGATGTAGCTATTAACTGGGGTGGTG
GATTGCATCATGCTAAGAAGGGAGAAGCTTATGGCTTCTGTTATGTTAATGATATAGTAA
TATGCATTTTGGAGCTTTTAAAAGTATTTCCTCGTGTGCTTTACATAGATATAGATGTAC
ACCATGGAGATGGCGTAGAAGAGGCTTTCTTTACTACAAATAGAGTAATGACAGTTAGTT
TTCATGAATTTGGAGAAGATTTCTTTCCTGGAACAGGTGGCCTCAACAGTAGTGGAGAAG
GATTGGGCAAAAATTATGCTGTGAATGTACCACTTAGACCTGGTATGGATGATGAAAGTT
ATAAATAACTATTTAAAAATGTAATGAATAAAGTAATGGAAGTGTTTAGACCTGACGTAG
TTGTATTCTAAACTGGAGCTGATAGTTTAGCTAATGACAAAATTGGGCATTTTAATTTAT
CTATTAGAGGACATGGCGAATGCTTGACTTACATGCTAAGGTTTAATGTTCCTGTAGTAG
TTTTAGGAGGAGGTGGATATACTATTTAAAATGTAAGTCGTTGCTGGGCATATGAAACAG
GATTACTTGTTAAAAAAAATTTAAATGGACCTATACCTGTTGATGATCCCTTTTTCCATT
TATATGAAAAATAGAATATGCTTCACGTTCCAATTTAGCAAGTAGAAAATAAGAATAGTA
AAGAAGATTTAAATAAAATATAAGAAGAGGTCTTTAAGCAACTAAAAGAAGTAGATGCTG
CCCCATCAATACCTTTTCATAATGTTCCCAAAGCATTCTAGTATGATGACGATGAATATT
TCGAGGAAAATGAATAAGATTAACATCATGATTTTTCTGGAAATACTTATAATTTCAATA
AGCTTAATGACTATATAAACGGATATTAAACAATGGAGGTCGAATAAAATGAAGAAGTTG
GAGTATATAGAAAACAACCTCTATTAATAGAAAAGAATAGTAGTAGATTTAATCATATTT
GA