Identifiers and Description

Gene Model Identifier

TTHERM_00112480

Standard Name

THD15 (Tetrahymena Histone Deacetylase 15)

Aliases

PreTt27062 | 8.m00322 | 3812.m02359

Description

Sir2-like histone deacetylase; suppresses DNA transcription by deacetylation of histones

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

Biological Process

Domains

No Data fetched for Domains

Gene Expression Profile

  • Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 13.8%

TetraMine Data

TTHERM_00112480

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

SourceIdentifierScoreDescription
Tetrahymena borealisEI9_03967.19.99838497179609e-146transcriptional regulator, Sir
2 family protein (309 aa)
OxytrichaContig9367.0.g587.998505003885351e-50Sir2 family
DictyBaseDDB_G02839178.000462645699572e-47sir2A on chromosome: 4 positio
n 1272110 to 1273864
WormBaseWBGene000048004.000139296874041e-45locus:sir-2.1 status:Partial
ly_confirmed UniProt:D3YT50
protein_id:CBK19468.1
SGDYPL015C1.999683289470905e-41HST2 Cytoplasmic member of the
silencing information regulat
or 2 (Sir2) family of NAD(+)-d
ependent protein deacetylases;
modulates nucleolar (rDNA) an
d telomeric silencing; possess
es NAD(+)-dependent histone de
acetylase activity in vitro
Stentor CoeruleusSteCoe_180277.095474162284704e-23

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:18178773: Smith JJ, Torigoe SE, Maxson J, Fish LC, Wiley EA (2008) A class II histone deacetylase acts on newly synthesized histones in Tetrahymena. Eukaryotic cell 7(3):471-82
  2. Ref:SUPR000192
  3. Ref:SUPR000138
  4. Ref:SUPR000135

Sequences

>TTHERM_00112480(coding)
ATGCATTTAAAAACACTCTTCAAATCATTAATTACTCCAAGTAAGTAAATTACTTTGAGA
ATATCTAACGTATAGCCAGTTATCAACAGTATTAAATTCGATTAAACAAATCATAGTATA
CATAACTCAATCTCACATGAAGTATAGGACAGATCTCAAATAATTGAGAATTTTGCTGAG
AAGTTGTTAGCAAAAAAATATAAATAGATAGCTTTCTTGACAGGAGCAGGAATTAGTGTA
AGTGCTGGAATTCCAGATTTTAGATCTCCTGAAACTGGGCTTTACGCCTAAATAAAAAAA
GAATATGACATAAGTGATCCTTAAAAAATATTTTCAATTAGATATTATCAAGATAATCCT
TTGCCTTTTATGCAAGTTATTAGAGATTTCTTTTCAAGAGAATATCACCCAACTTATGCT
CATAAGTTAATCCATTAAATCTACAAAAGAAAACAACTATTAATAAATATAACCTAAAAT
ATTGATGGCTTAGAGTTAAAAACAGGGATTAATCCCTCAAAAGTAGTCTAAGCACATGGA
CATATGAGAAAGGCTCATTGTGTGAATTGCAATCATATTGTCAATATTGAAACTTACTTA
CAAAACTGCAAACAGTTAAAAAAAACCTAATGCCCCATTTGCAATAATTTAGTGAAGCCA
AAAATTGTTTTCTTTGGAGAGTTTCTTCCTAATGAGTTTTATTAGTCTAGAGATATTTTG
CCAAATTCAGATTGTGTGGTTGTTATGGGAACATCTTTAGGTGTCTTTCCATTTGCTAAT
TTAATAAACGAAGTAGGTACTTCTGTTCCAATATATATAATAAACAATAAACTTCCTAAA
AATATAAGTCATCTTAAAAATCAAATTGAATTTATATAAGGAGATATCAATGAAATTTCT
AAATAAATTATTGATTACATAAATTGA


>TTHERM_00112480(protein)
MHLKTLFKSLITPSKQITLRISNVQPVINSIKFDQTNHSIHNSISHEVQDRSQIIENFAE
KLLAKKYKQIAFLTGAGISVSAGIPDFRSPETGLYAQIKKEYDISDPQKIFSIRYYQDNP
LPFMQVIRDFFSREYHPTYAHKLIHQIYKRKQLLINITQNIDGLELKTGINPSKVVQAHG
HMRKAHCVNCNHIVNIETYLQNCKQLKKTQCPICNNLVKPKIVFFGEFLPNEFYQSRDIL
PNSDCVVVMGTSLGVFPFANLINEVGTSVPIYIINNKLPKNISHLKNQIEFIQGDINEIS
KQIIDYIN


>TTHERM_00112480(gene)
ATGCATTTAAAAACACTCTTCAAATCATTAATTACTCCAAGTAAGTAAATTACTTTGAGA
ATATCTAACGTATAGCCAGTTATCAACAGTATTAAATTCGATTAAACAAATCATAGTATA
CATAACTCAATCTCACATGAAGTATAGGACAGATCTCAAATAATTGAGAATTTTGCTGAG
AAGTTGTTAGCAAAAAAATATAAATAGATAGCTTTCTTGACAGGAGCAGGAATTAGTGTA
AGTGCTGGAATTCCAGATTTTAGATCTCCTGAAACTGGGCTTTACGCCTAAATAAAAAAA
GAATATGACATAAGTGATCCTTAAAAAATATTTTCAATTAGATATTATCAAGATAATCCT
TTGCCTTTTATGCAAGTTATTAGAGATTTCTTTTCAAGAGAATATCACCCAACTTATGCT
CATAAGTTAATCCATTAAATCTACAAAAGAAAACAACTATTAATAAATATAACCTAAAAT
ATTGATGGCTTAGAGTTAAAAACAGGGATTAATCCCTCAAAAGTAGTCTAAGCACATGGA
CATATGAGAAAGGCTCATTGTGTGAATTGCAATCATATTGTCAATATTGAAACTTACTTA
CAAAACTGCAAACAGTTAAAAAAAACCTAATGCCCCATTTGCAATAATTTAGTGAAGCCA
AAAGTAATTTTATTTCTTTGTTTAAATTTTAATTGTAATGCTAGCAAAAATATAGGAAAT
AAAAATTAGAAATTATTGGCACAATTAGTTGAAAAAAATAAATATTTTAAATTTCAATCA
AAAATATTTATTGAGAATCAACTTTATTTATTATTGAAATTTATCAGTTAGTTTCCATAT
CATAAATTTTTTATATTTATAAAAATAAAAGATTGTTTTCTTTGGAGAGTTTCTTCCTAA
TGAGTTTTATTAGTCTAGAGATATTTTGCCAAATTCAGATTGTGTGGTTGTTATGGGAAC
ATCTTTAGGTGTCTTTCCATTTGCTAATTTAATAAACGAAGTAGGTACTTCTGTTCCAAT
ATATATAATAAACAATAAACTTCCTAAAAATATAAGTCATCTTAAAAATCAAATTGAATT
TATATAAGGAGATATCAATGAAATTTCTAAATAAATTATTGATTACATAAATTGA