Identifiers and Description

Gene Model Identifier

TTHERM_00691200

Standard Name

TFIIS

Aliases

PreTt02958 | 106.m00098 | 3674.m00011

Description

transcription factor S-II; transcription factor S-II. Interacts with transcription regulator Mediator complex in Tetrahymena.

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• nucleus (IEA) | GO:0005634

Molecular Function

• protein binding (IEA) | GO:0005515
• DNA binding (IEA) | GO:0003677
• obsolete transcription regulator activity (IEA) | GO:0030528
• nucleic acid binding (IEA) | GO:0003676
• zinc ion binding (IEA) | GO:0008270

Biological Process

• transcription (IEA) | GO:0006350
• regulation of transcription (IEA) | GO:0045449

Domains

• ( TIGR01384 ) transcription factor S
• ( TIGR01784 ) conserved hypothetical protein
• ( PF01096 ) transcription factor S-II (TFIIS)
• ( TIGR01385 ) transcription elongation factor S-II
• ( PF08711 ) Transcription elongation factor S-II protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00691200

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17617.1	9.997316819378982e-180	transcription factor S-II (324 aa)
SGD	YDR045C	0.0000029996948234116693	RPC11 RNA polymerase III subun it C11; mediates pol III RNA c leavage activity and is import ant for termination of transcr iption; homologous to TFIIS
WormBase	WBGene00012000	0.00003998524687536623	Putative transcription elongat ion factor S-II status:Parti ally_confirmed UniProt:P5265 2 protein_id:CAA90943.1
Oxytricha	Contig14486.0.g34	0.0004000184047659232	Transcription factor S-II (TFI IS), central domain

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31280994: Garg J, Saettone A, Nabeel-Shah S, Cadorin M, Ponce M, Marquez S, Pu S, Greenblatt J, Lambert JP, Pearlman RE, Fillingham J (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current biology : CB 29(14):2371-2379.e6

Sequences

>TTHERM_00691200(coding)
ATGGATCAACTATACACAGAAGATGAATTGACTGAATTCAAAAACGATTTGAGAAAGTTT
AAGGAAATTGGAAATACTAAAGTTTTGGCCATCGTAAAAAGACTTTTTAATTGCCAAATC
ACAGTATAATAATTATAAAACACTAAAATTGCTTAAACTGTGTAATCTCTCTCTACTATG
TCTTGCTTCGATGAAGATGAAGAAGGACAAGAAGCTAAATAAATATGCTCTTAAATTATT
AACAAATGGAAAAAAATAGTTTAAAATGAAAAAAATAAGCAAAATCCTCAAGCCTCAAGC
TAAAAAGCACCACAATTAACTAAATCAAATTCACAAACTGCTACTTTGCCTAGAAGATAA
TCCTCTGGTTAAGGTTCTACTGAAACATTTTTAACTAATGAGGAACCCTAATACAAGACA
GAATCAAAAACTGATCTTCCTACTTATAAAAGTGATATTCGCTAAAAAGGATTAGAAGCT
ATTAACAAAATTTTTATGAAGGTTAAAGATGATATTAATGCTTCTCCTAGAGAATGGATT
GAATTAATTGTAAATCTTGAAAAGAAAATTTTCTCAAGAAATTCCTAAGTAGTTTACTAT
AAATCTTATATTAAAGAAGTCCTTGGTATGTTCTCTTCTAATGAAGTTACCACTGAGGTT
ATTTCTAAAATGTTAAATAAAGAAATTTCACTTTAGGATGTTGCTGAAGCAAAAACTAGT
GTCTTCTTGACTGATAGATAAAGAGCCTAGCAAAAAAAAGCTGTTGAAGATTAGCTTGCT
ACAAGTGATCCAGATTTTTATAACAATATGCGTAGATAGCGTTTACAAGGTCTAGAAGGT
GAATTATGTAAAGGATGTAAGAAAAAAACAGCTTTCTTAGTAAAAGAATTATAGACTCGT
TCATCAGATGAACCTATGACTCGTTTTATGGAATGCAATAGCTGTGGTAAAAGTTGGAAA
GACTGA

>TTHERM_00691200(protein)
MDQLYTEDELTEFKNDLRKFKEIGNTKVLAIVKRLFNCQITVQQLQNTKIAQTVQSLSTM
SCFDEDEEGQEAKQICSQIINKWKKIVQNEKNKQNPQASSQKAPQLTKSNSQTATLPRRQ
SSGQGSTETFLTNEEPQYKTESKTDLPTYKSDIRQKGLEAINKIFMKVKDDINASPREWI
ELIVNLEKKIFSRNSQVVYYKSYIKEVLGMFSSNEVTTEVISKMLNKEISLQDVAEAKTS
VFLTDRQRAQQKKAVEDQLATSDPDFYNNMRRQRLQGLEGELCKGCKKKTAFLVKELQTR
SSDEPMTRFMECNSCGKSWKD

>TTHERM_00691200(gene)
ATGGATCAACTATACACAGAAGATGAATTGACTGAATTCAAAAACGATTTGAGAAAGTTT
AAGGAAATTGGAAATACTAAAGTTTTGGCCATCGTAAAAAGACTTTTTAATTGCCAAATC
ACAGTATAATAATTATAAAACACTAAAATTGCTTAAACTGTGTAATCTCTCTCTACTATG
TCTTGCTTCGATGAAGATGAAGAAGGACAAGAAGCTAAATAAATATGCTCTTAAATTATT
AACAAATGGAAAAAAATAGTTTAAAATGAAAAAAATAAGCAAAATCCTCAAGCCTCAAGC
TAAAAAGCACCACAATTAACTAAATCAAATTCACAAACTGCTACTTTGCCTAGAAGATAA
TCCTCTGGTTAAGGTTCTACTGAAACATTTTTAACTAATGAGGAACCCTAATACAAGACA
GAATCAAAAACTGATCTTCCTACTTATAAAAGTGATATTCGCTAAAAAGGATTAGAAGCT
ATTAACAAAATTTTTATGAAGGTTAAAGATGATATTAATGCTTCTCCTAGAGAATGGATT
GAATTAATTGTAAATCTTGAAAAGAAAATTTTCTCAAGAAATTCCTAAGTAGTTTACTAT
AAATCTTATATTAAAGAAGTCCTTGGTATGTTCTCTTCTAATGAAGTTACCACTGAGGTT
ATTTCTAAAATGTTAAATAAAGAAATTTCACTTTAGGATGTTGCTGAAGCAAAAACTAGT
GTCTTCTTGACTGATAGATAAAGAGCCTAGCAAAAAAAAGCTGTTGAAGATTAGCTTGCT
ACAAGTGATCCAGATTTTTATAACAATATGCGTAGATAGCGTTTACAAGGTCTAGAAGGT
GAATTATGTAAAGGATGTAAGAAAAAAACAGCTTTCTTAGTAAAAGAATTATAGACTCGT
TCATCAGATGAACCTATGACTCGTTTTATGGAATGCAATAGCTGTGGTAAAAGTTGGAAA
GACTGA