Identifiers and Description

Gene Model Identifier

TTHERM_00551160

Standard Name

TDH1 (glyceraldehyde-3-phosphate dehydrogenase 1)

Aliases

PreTt29220 | 72.m00143 | GapC

Description

Glyceraldehyde-3-phosphate dehydrogenase; metabolic enzyme involved in glycoloysis

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytosol (ISS) | GO:0005829 | Ref:11230543

Molecular Function

• glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (IEA) | GO:0004365
• obsolete glyceraldehyde-3-phosphate dehydrogenase activity (ISS) | GO:0008943 | Ref:11230543
• NAD binding (IEA) | GO:0051287

Biological Process

• glucose metabolic process (IEA) | GO:0006006
• glycolytic process (ISS) | GO:0006096 | Ref:11230543
• oxidation-reduction process (IEA) | GO:0055114

Domains

• ( PF04641 ) Protein of unknown function, DUF602
• ( PF04725 ) Photosystem II 10 kDa polypeptide
• ( TIGR01532 ) D-erythrose-4-phosphate dehydrogenase
• ( TIGR01534 ) glyceraldehyde-3-phosphate dehydrogenase, type I
• ( PF02800 ) Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
• ( PF00044 ) Glyceraldehyde 3-phosphate dehydrogenase, NAD binding

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 23.6%

TetraMine Data

TTHERM_00551160

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_07327.1	9.997093137033517e-262	glyceraldehyde-3-phosphate deh ydrogenase, type I family prot ein (343 aa)
Oxytricha	Contig18741.0.g63	1.999126889527329e-167	Glyceraldehyde 3-phosphate deh ydrogenase, C-terminal domain
DictyBase	DDB_G0275153	2.0007442334946695e-153	gpdA on chromosome: 2 position 5324765 to 5325948
WormBase	WBGene00001686	2.0003615238957836e-139	locus:gpd-4 Glyceraldehyde-3 -phosphate dehydrogenase 4 s tatus:Confirmed UniProt:P173 31 protein_id:CAA88697.1
SGD	YJL052W	2.998636664422997e-137	TDH1 Glyceraldehyde-3-phosphat e dehydrogenase, isozyme 1, in volved in glycolysis and gluco neogenesis; tetramer that cata lyzes the reaction of glyceral dehyde-3-phosphate to 1,3 bis- phosphoglycerate; detected in the cytoplasm and cell wall
Stentor Coeruleus	SteCoe_24164	1.1983630608508849e-70

General Information

No Data fetched for General Information

Associated Literature

1. Ref:11230543: Fast NM, et al. (2001) Nuclear-encoded, plastid-targeted genes suggest a single common origin for apicomplexan and dinoflagellate plastids. Mol Biol Evol 18(3):418-26
2. Ref:9734334: Hafid N, Valverde F, Villalobo E, Elkebbaj MS, Torres A, Soukri A, Serrano A (1998) Glyceraldehyde-3-phosphate dehydrogenase from Tetrahymena pyriformis: enzyme purification and characterization of a gapC gene with primitive eukaryotic features. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 119(3):493-503
3. Ref:9304812: Zhao Y, Nakashima S, Andoh M, Nozawa Y (1997) Cloning and sequencing of a cDNA encoding glyceraldehyde-3-phosphate dehydrogenase from Tetrahymena thermophila: growth-associated changes in its mRNA expression. The Journal of eukaryotic microbiology 44(5):435-7

Sequences

>TTHERM_00551160(protein)
MALRLGINGFGRIGRLVLRAAVENHANEVKVVAINDPFMDVDYLIYQLKYDSAHLKFPGK
IEKVDDHTIKVNGNNITLFKEKDPAALKWGDAGADFVCESTGAFLTQEKAAAHLKGGAKK
VILSAPAKDDTPTFVFGVNHKNYNPSQNIISNASCTTNCLAPVAKVLHEKFGIAEGLMTT
VHASTATQLVVDGPSKGGKDWRAGRAASTNIIPSSTGAAKAVGLVLPALKGKLTGMSFRV
PTINVSVVDLTVRLEKGTTYANICEAMKEASEGELKGILGYTKEEVVSQDFMHDARTSIF
DHKAGIGLNDNFHKIISWYDNEWGYSNKLIDLALHVKKTSGL

>TTHERM_00551160(coding)
ATGGCTTTGAGATTAGGTATTAACGGTTTTGGTAGAATCGGTAGATTAGTATTAAGAGCT
GCTGTTGAAAACCACGCCAACGAAGTCAAGGTTGTTGCTATCAACGATCCCTTCATGGAT
GTCGACTACCTCATTTACTAATTGAAGTACGACTCTGCTCACCTTAAGTTCCCTGGTAAA
ATCGAAAAGGTTGACGACCACACCATCAAGGTCAACGGTAACAACATCACCTTGTTCAAG
GAAAAGGATCCCGCTGCTTTAAAGTGGGGTGATGCTGGTGCTGATTTCGTTTGCGAATCC
ACTGGTGCTTTCCTTACCTAAGAAAAGGCTGCTGCTCACTTGAAGGGTGGTGCTAAGAAG
GTCATTCTCTCTGCCCCTGCTAAGGATGACACTCCTACCTTCGTCTTCGGTGTTAACCAC
AAGAACTACAACCCCTCCTAAAACATTATTTCCAACGCTTCTTGCACTACCAACTGTCTT
GCTCCCGTTGCTAAGGTCCTCCACGAAAAGTTCGGAATTGCTGAAGGTCTCATGACCACT
GTCCACGCCTCCACTGCTACCTAATTGGTTGTTGATGGTCCCTCCAAGGGTGGTAAGGAC
TGGAGAGCTGGTAGAGCTGCCTCAACCAACATCATTCCTTCTTCCACTGGTGCTGCTAAG
GCTGTCGGTCTAGTTCTCCCTGCCTTGAAGGGTAAGTTGACTGGTATGTCCTTCAGAGTT
CCTACCATTAACGTCTCTGTCGTTGATCTTACCGTCAGACTCGAAAAGGGTACCACCTAT
GCTAACATTTGTGAAGCCATGAAGGAAGCCTCCGAAGGTGAACTCAAGGGTATCTTGGGT
TACACCAAGGAAGAAGTCGTCTCTCAAGACTTCATGCATGATGCCAGAACCTCCATCTTC
GATCACAAGGCTGGTATTGGTTTGAATGATAACTTCCACAAGATCATTTCTTGGTATGAT
AACGAATGGGGTTACTCTAATAAGTTAATTGACCTCGCTCTTCACGTCAAGAAGACCTCT
GGACTCTGA

>TTHERM_00551160(gene)
ATGGCTTTGAGATTAGGTATTAACGGTTTTGGTAGAATCGGTAGATTAGTATTAAGAGCT
GCTGTTGAAAACCACGCCAACGAAGTCAAGGTTGTTGCTATCAACGATCCCTTCATGGAT
GTCGACTACCTCATTTACTAATTGAAGTACGACTCTGCTCACCTTAAGTTCCCTGGTAAA
ATCGAAAAGGTAATTAACTAATTAATTTATTAACTAACTATTTAACTCATTATTTGGTTA
TGTATTTTCGTTCAAACTCTACTTATATACCTTCAAACCTCTTTCACTAATACCCATCAA
ATAAGCAAATATCTTTTTTCCAACACTGCTCTTGTTATAGGAAATATGGTAGTTATACGA
CACCACTATTTCTTTAGTCATTTTGACCTTTTTCTTTTGAGTAGGATTCAATCTCATTAT
GAATGATGAGTTTCATTTCTCATTTTTGAACATATAATATTCTAATATTCTACTCAACCC
ATTTAAAGAGAGAGAGAGAGGAAGATATAAACGAAAAACAAACAAAGAGGAATTCATGAA
ATATCATTTACTAATACTTATTTATTTATAAATAAAGGTTGACGACCACACCATCAAGGT
CAACGGTAACAACATCACCTTGTTCAAGGAAAAGGATCCCGCTGCTTTAAAGTGGGGTGA
TGCTGGTGCTGATTTCGTTTGCGAATCCACTGGTGCTTTCCTTACCTAAGAAAAGGCTGC
TGCTCACTTGAAGGGTGGTGCTAAGAAGGTCATTCTCTCTGCCCCTGCTAAGGATGACAC
TCCTACCTTCGTCTTCGGTGTTAACCACAAGAACTACAACCCCTCCTAAAACATTATTTC
CAACGCTTCTTGCACTACCAACTGTCTTGCTCCCGTTGCTAAGGTCCTCCACGAAAAGTT
CGGAATTGCTGAAGGTCTCATGACCACTGTCCACGCCTCCACTGCTACCTAATTGGTTGT
TGATGGTCCCTCCAAGGGTGGTAAGGACTGGAGAGCTGGTAGAGCTGCCTCAACCAACAT
CATTCCTTCTTCCACTGGTGCTGCTAAGGCTGTCGGTCTAGTTCTCCCTGCCTTGAAGGG
TAAGTTGACTGGTATGTCCTTCAGAGTTCCTACCATTAACGTCTCTGTCGTTGATCTTAC
CGTCAGACTCGAAAAGGGTACCACCTATGCTAACATTTGTGAAGCCATGAAGGAAGCCTC
CGAAGGTGAACTCAAGGTAATTATTAATTCCCTTTAAAAATGCTAATTATTAAACTTAAA
GAGAATAAATACTACATAAATAAGGATAAATGCTAACAAAAAGGGCCGAAATATACTTAA
TTGTATAGCTCAGGCTTTCTATTTTATTGATAAAAAAAAAAATATAGGCATTTAACAAAG
ATAACATATTATCTTTTAATTTAAAGCTAAAGCTTTTCAAATACATTTTAAATAAAAAGC
AATGCTCATTCTTTTTAAAAATATTAATGAGTTAATTAAAAAGCTATAAATTAAATTAAG
AGATTCTATTTTTTTATTTTTTTGTTTTTTACTTTTATTAATTCATATATTCATTCGTTT
TTAACTCATTATTTTCTAATTATAGGGTATCTTGGGTTACACCAAGGAAGAAGTCGTCTC
TCAAGACTTCATGCATGATGCCAGAACCTCCATCTTCGATCACAAGGCTGGTATTGGTTT
GAATGATAACTTCCACAAGATCATTTCTTGGTATGATAACGAATGGGGTTACTCTAATAA
GTTAATTGACCTCGCTCTTCACGTCAAGAAGACCTCTGGACTCTGA