Identifiers and Description

Gene Model Identifier

TTHERM_00495950

Standard Name

TCB1 (Tetrahymena Calcium-Binding protein )

Aliases

PreTt06860 | 62.m00144 | TCBP-23 | 3715.m00006

Description

TCB1 EF hand protein; 23 kD EF-hand containing Ca(2+)-binding protein; localized to cell cortex- except for the oral apparatus and around the basal bodies; likely associated with the epiplasm

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cortical cytoskeleton (IDA) | GO:0030863 | Ref:8797091

Domains

• ( PF00036 ) EF hand

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12.8%

TetraMine Data

TTHERM_00495950

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_12786.1	2.0006597401342834e-129	EF hand family protein (207 aa )
Oxytricha	Contig605.1.g93	0.000000000800327577657144	EF hand
WormBase	WBGene00000960	0.00000030014504373857585	locus:dgk-3 Probable diacylg lycerol kinase 3 status:Part ially_confirmed UniProt:Q036 03 protein_id:CAA79558.3
DictyBase	DDB_G0287009	0.00003998524687536623	mcfC on chromosome: 4 position 5197882 to 5199603
SGD	YBR109C	0.00020003864201578029	CMD1 Calmodulin; Ca++ binding protein that regulates Ca++ in dependent processes (mitosis, bud growth, actin organization , endocytosis, etc.) and Ca++ dependent processes (stress-ac tivated pathways), targets inc lude Nuf1p, Myo2p and calcineu rin

General Information

No Data fetched for General Information

Associated Literature

1. Ref:10503211: Numata O, Hanyu K, Takeda T, Watanabe Y (2000) Tetrahymena calcium-binding proteins, TCBP-25 and TCBP-23. Methods in cell biology 62( ):455-65
2. Ref:8797091: Hanyu K, Numata O, Takahashi M, Watanabe Y (1996) Immunofluorescence localization of a 23-kDa Tetrahymena calcium-binding protein, TCBP-23, in the cell cortex. Journal of biochemistry 119(5):914-9
3. Ref:2303413: Takemasa T, Takagi T, Kobayashi T, Konishi K, Watanabe Y (1990) The third calmodulin family protein in Tetrahymena. Cloning of the cDNA for Tetrahymena calcium-binding protein of 23 kDa (TCBP-23). The Journal of biological chemistry 265(5):2514-7

Sequences

>TTHERM_00495950(coding)
ATGGAACACCAAATCATCACCTAAAACGTCTACGCTCCTGATACTGAAGCCAAGCTTGAT
GTTGCTAGAAAGCTTTTTGCTTAGTTTGATTCTAACAAGAACGGTACTTTAGATCCTAGC
GAAGTTGCTGGACTCATCAAGACTACTTTTGAAAATATGGGTGTTAAGGACTACAGCGTC
ACTGCTGATGATGTCAAGCTTTACATGAAGAGTGTTGATGTTGATAACAACGGTCTTGTT
TCCTACTCTGAATACGAAGAATACGTCATTGCTTGCCTCAAGAAAGCTGGCTTCGACTGT
GAAGTTAAGGAAAAGGTAAAAAGATCTGCCAAAAAGAGAGACGCTGCTACTGAAATGAAG
TTGGACGTTGCCAGAAGACTCTTCGCTAAGTACGACTCTGATAAGAGTGGTTAATTAGAA
GAAAAGGAAGTTTATGGTGTCATTACTGAAACCTATAAGCAAATGGGTATGGATTACAAG
CCCACTGAAGCTGATGTTAAGCTTTGGATGTCCATGACTGATACTGATAAGAATGGAACT
GTCTCTATTGTTGAATATGAAGATTTCGTCATTTCTGGTCTTAAGAAGGCTGGTTTCATG
GTCAAGGAATTCACTCAAGCTTGA

>TTHERM_00495950(protein)
MEHQIITQNVYAPDTEAKLDVARKLFAQFDSNKNGTLDPSEVAGLIKTTFENMGVKDYSV
TADDVKLYMKSVDVDNNGLVSYSEYEEYVIACLKKAGFDCEVKEKVKRSAKKRDAATEMK
LDVARRLFAKYDSDKSGQLEEKEVYGVITETYKQMGMDYKPTEADVKLWMSMTDTDKNGT
VSIVEYEDFVISGLKKAGFMVKEFTQA

>TTHERM_00495950(gene)
ATGGAACACCAAATCATCACCTAAAACGTCTACGCTCCTGATACTGAAGCCAAGCTTGAT
GTTGCTAGAAAGCTTTTTGCTTAGTTTGATTCTAACAAGAACGGTACTTTAGATCCTAGC
GAAGTTGCTGGACTCATCAAGACTACTTTTGAAAATATGGGTGTTAAGGACTACAGCGTC
ACTGCTGATGATGTCAAGCTTTACATGAAGAGTGTTGATGTTGATAACAACGGTCTTGTT
TCCTACTCTGAATACGAAGAATACGTCATTGCTTGCCTCAAGAAAGCTGGCTTCGACTGT
GAAGTTAAGGAAAAGGTAAAAAGATCTGCCAAAAAGAGAGACGCTGCTACTGAAATGAAG
TTGGACGTTGCCAGAAGACTCTTCGCTAAGTACGACTCTGATAAGAGTGGTTAATTAGAA
GAAAAGGAAGTTTATGGTGTCATTACTGAAACCTATAAGCAAATGGGTATGGATTACAAG
CCCACTGAAGCTGATGTTAAGCTTTGGATGTCCATGACTGATACTGATAAGAATGGAACT
GTCTCTATTGTTGAATATGAAGATTTCGTCATTTCTGGTCTTAAGAAGGCTGGTTTCATG
GTCAAGGAATTCACTCAAGCTTGA