Identifiers and Description

Gene Model Identifier

TTHERM_00526730

Standard Name

TAP1 (Tetrahymena Amino acid Permease )

Aliases

PreTt06411 | 66.m00210 | 3722.m00068

Description

TAP1 transmembrane amino acid transporter protein; Amino acid permease 1; similar to proton driven amino-acid pumps of the UNC-47/VGAT family

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• membrane (IEA) | GO:0016020

Molecular Function

• amino acid transmembrane transporter activity (ISS) | GO:0015171 | Ref:12456006
• amino acid-polyamine transporter activity (IEA) | GO:0005279

Biological Process

• amino acid transport (IEA) | GO:0006865
• vesicle organization (IEP) | GO:0016050 | Ref:12456006

Domains

• ( PF00950 ) ABC 3 transport family
• ( PF03845 ) Spore germination protein
• ( PF07672 ) Mycoplasma MFS transporter
• ( TIGR02614 ) cell division protein FtsW
• ( PF01148 ) phosphatidate cytidylyltransferase
• ( PF07695 ) 7TM diverse intracellular signalling
• ( PF00001 ) 7 transmembrane receptor (rhodopsin family)
• ( PF01490 ) Transmembrane amino acid transporter protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00526730

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_13414.1	9.997093137033517e-262	transmembrane amino acid trans porter (552 aa)
Oxytricha	Contig4642.0.g78	3.998693556225637e-29	Transmembrane amino acid trans porter protein
SGD	YNL101W	7.996210139153865e-29	AVT4 Vacuolar transporter, exp orts large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to ves icular GABA-glycine transporte rs
WormBase	WBGene00012804	3.9989916100764785e-24	status:Confirmed UniProt:O45 936 protein_id:CAA16336.2
DictyBase	DDB_G0293074	0.0007999190683310628	DDB_G0293074 on chromosome: 6 position 2437739 to 2439363

General Information

No Data fetched for General Information

Associated Literature

1. Ref:12456006: Haddad A, Bowman GR, Turkewitz AP (2002) New class of cargo protein in Tetrahymena thermophila dense core secretory granules. Eukaryotic cell 1(4):583-93
2. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences

>TTHERM_00526730(coding)
ATGAAGTCCAATAAAAAGTAGTAGAAAAGATAATAAGAAAGGCATGACGACCCAGATTTA
GAGCCCTTGAACAAAAAAAACGATGAATAAGTTATAGAAACTGATGAGGGCGTAATTAAG
AATCGCAGTTCATAAAAAGAAGAAAAAAAGAGCTACTAATCAAATTAGAGTGATGGAAGT
AGAATATAAAAAAGATAATCTCAAGATCAAGAAAATTGGAGTGATGATTCAGCAGAAGAA
GCTAATTAAATTGATGACTTGAAACATGAAGAAAAGGCTGATGTTTGGAATGCAACTATA
AATATGGTTAAGGGATTTGTTGGAATCGGTATTTTAGCACTACCTTCAGGTTTTGCTAAG
AGTGGTTGGTTGGGAGGATTAATAATTTTTTTGCTTTGCGCTGGAATGGTTCTTTATTTA
AGTTTATAGATGATGGATGCAGCAAACAAAAGAAAATCTTAAGCTAGAGGTGTTACCTAA
TTCAGTGTTGAAGTTTTGGGATAAGAAAAAGAATTATTAGTTAATATATTTTTATTTGGA
ATCTAAATTGGAATTTGTGTTGCCTATGTTATTTTCTTCACTACTTATTTTTAAGAGAGT
CTTTGTTTCTTTGTAGATTATGATCGTACAACTAATGTATGTGGTTCAAGAGTTCCTTCG
TTACTCATTTCACTTATAATCGTTACTCCTACAATATTTATCAGACACATGAGTAAACTT
AAAACTTGGAGCATGTTTTCAAATAGTTTAATTCTTATTAGTATGCTTGTAGTATTTATT
TCTTGCTTTTTTAAAATGGACACTTCTTACATTACTAGTGACAAAATTTCAGCTATCAGA
TGGGGAGAAATGGGTAGTGCAATAGGTTTATTTGTGTTTGCATTTGAAGGAACCACTCTT
TATTTTGAAATTAGGAGTTCTATGCAAGAACCAACTGAGTTCAAAAAGGTTCTTAATTAT
TCTCTTTATATTGGTATTGCTCTTTATGGGTGCATTGGTTTGAGTGGATATTTAGCTTTT
GGATCAGGTGTTAGAGACATCATACTTTTTAATTTCCCTATGACTAATCCCTTGTATGTT
TTTATTTAAATCTTTTACTGTATAGCAATATTGTTATCCTATCCTCTTCAGATGTTCCCT
TTAGTCAATATCTTAGAATAAAAATTATTAGAAAGGATAGTCAATGAAAAGAATAAATAA
AAAACAAATAGCTAGCCCTAAAAAAAGTCATAGCAAGGTGTAGATTAAAGCCAACATCAT
AATTAAGGTAATCAGCAAGCAGACGATAGATAAGATAACTAGGAATCTGATGCATCAGAA
GGAAATGCATTGAACTTATTAACATAATATGATGATGAAATAAAAAATTCATTTTACTAA
TAAAGCATGATATTAAGAGTAGCTTCTCTTTTATTCATATTCTTTTTTGCAATCGTCTTT
AAAAGACTAACTGTCTTTTTAAATTTAATTGGTTCTATTGGTGGTTGCTTTTTTGCATTT
ATTTTACCAGTCATTGTCTATGAGTATTCTATGCCAGAAGCTTCACAAAAAAAAATATAC
TTTCACAGAGGCTTACTTGTACTAGGTGTTATTTTTTCCTTCTTTGGTACTCTTTCTAGT
TTAAGAGATATCTATAGATCGTTATGA

>TTHERM_00526730(protein)
MKSNKKQQKRQQERHDDPDLEPLNKKNDEQVIETDEGVIKNRSSQKEEKKSYQSNQSDGS
RIQKRQSQDQENWSDDSAEEANQIDDLKHEEKADVWNATINMVKGFVGIGILALPSGFAK
SGWLGGLIIFLLCAGMVLYLSLQMMDAANKRKSQARGVTQFSVEVLGQEKELLVNIFLFG
IQIGICVAYVIFFTTYFQESLCFFVDYDRTTNVCGSRVPSLLISLIIVTPTIFIRHMSKL
KTWSMFSNSLILISMLVVFISCFFKMDTSYITSDKISAIRWGEMGSAIGLFVFAFEGTTL
YFEIRSSMQEPTEFKKVLNYSLYIGIALYGCIGLSGYLAFGSGVRDIILFNFPMTNPLYV
FIQIFYCIAILLSYPLQMFPLVNILEQKLLERIVNEKNKQKTNSQPQKKSQQGVDQSQHH
NQGNQQADDRQDNQESDASEGNALNLLTQYDDEIKNSFYQQSMILRVASLLFIFFFAIVF
KRLTVFLNLIGSIGGCFFAFILPVIVYEYSMPEASQKKIYFHRGLLVLGVIFSFFGTLSS
LRDIYRSL

>TTHERM_00526730(gene)
ATGAAGTCCAATAAAAAGTAGTAGAAAAGATAATAAGAAAGGCATGACGACCCAGATTTA
GAGCCCTTGAACAAAAAAAACGATGAATAAGTTATAGAAACTGATGAGGGCGTAATTAAG
AATCGCAGTTCATAAAGTAAGGAGAAGATCTTTAAATATTTTAAAGAATTGTTAATAATC
ATTTTATTTGATTATTTGGAATTTATTTTTTTTATATAATTTCAAAGAAGAAGAAAAAAA
GAGCTACTAATCAAATTAGAGTGATGGAAGTAGAATATAAAAAAGATAATCTCAAGATCA
AGAAAATTGGAGTGATGATTCAGCAGAAGAAGCTAATTAAATTGATGACTTGAAACATGA
AGAAAAGGCTGATGTTTGGAATGCAACTATAAATATGGTTAAGGGATTTGTTGGAATCGG
TATTTTAGCACTACCTTCAGGTTTTGCTAAGAGTGGTTGGTTGGGAGGATTAATAATTTT
TTTGCTTTGCGCTGGAATGGTTCTTTATTTAAGTTTATAGATGATGGATGCAGCAAACAA
AAGAAAATCTTAAGCTAGAGGTGTTACCTAATTCAGTGTTGAAGTTTTGGGATAAGAAAA
AGAATTATTAGTTAATATATTTTTATTTGGAATCTAAATTGGAATTTGTGTTGCCTATGT
TATTTTCTTCACTACTTATTTTTAAGAGAGTCTTTGTTTCTTTGTAGATTATGATCGTAC
AACTAATGTATGTGGTTCAAGAGTTCCTTCGTTACTCATTTCACTTATAATCGTTACTCC
TACAATATTTATCAGACACATGAGTAAACTTAAAACTTGGAGCATGTTTTCAAATAGTTT
AATTCTTATTAGTATGCTTGTAGTATTTATTTCTTGCTTTTTTAAAATGGACACTTCTTA
CATTACTAGTGACAAAATTTCAGCTATCAGATGGGGAGAAATGGGTAGTGCAATAGGTTT
ATTTGTGTTTGCATTTGAAGGAACCACTCTTTATTTTGAAATTAGGTAAATTTATTTCAC
AAAAATTTTTTTAAATAATTTTTTAAAATAACAATTTTTTTCAAATTAATAGGAGTTCTA
TGCAAGAACCAACTGAGTTCAAAAAGGTTCTTAATTATTCTCTTTATATTGGTATTGCTC
TTTATGGGTGCATTGGTTTGAGTGGATATTTAGCTTTTGGATCAGGTGTTAGAGACATCA
TACTTTTTAATTTCCCTATGACTAATCCCTTGTATGTTTTTATTTAAATCTTTTACTGTA
TAGCAATATTGTTATCCTATCCTCTTCAGATGTTCCCTTTAGTCAATATCTTAGAATAAA
AATTATTAGAAAGGATAGTCAATGAAAAGAATAAATAAAAAACAAATAGCTAGCCCTAAA
AAAAGTCATAGCAAGGTGTAGATTAAAGCCAACATCATAATTAAGGTAATCAGCAAGCAG
ACGATAGATAAGATAACTAGGAATCTGATGCATCAGAAGGAAATGCATTGAACTTATTAA
CATAATATGATGATGAAATAAAAAATTCATTTTACTAATAAAGCATGATATTAAGAGTAG
CTTCTCTTTTATTCATATTCTTTTTTGCAATCGTCTTTAAAAGACTAACTGTCTTTTTAA
ATTTAATTGGTTCTATTGGTGGTTGCTTTTTTGCATTTATTTTACCAGTCATTGTCTATG
AGTATTCTATGCCAGAAGCTTCACAAAAAAAAATATACTTTCACAGAGGCTTACTTGTAC
TAGGTGTTATTTTTTCCTTCTTTGGTACTCTTTCTAGTTTAAGAGATATCTATAGATCGT
TATGA