Identifiers and Description

Gene Model Identifier

TTHERM_00410130

Standard Name

SMT3 (Suppressor of Mif Two )

Aliases

PreTt21530 | 44.m00197 | 3714.m00044 | SUMO

Description

small ubiquitin-related modifier (SUMO), conjugated to lysine residues on target proteins, post-translational modification,

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00240 ) Ubiquitin family

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00410130

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Oxytricha	Contig18025.0.g12	9.995528898049344e-31	Ubiquitin-2 like Rad60 SUMO-li ke
DictyBase	DDB_G0286189	5.00179831534194e-27	sumo on chromosome: 4 position 4217038 to 4217552
SGD	YDR510W	9.995317835403734e-19	SMT3 Ubiquitin-like protein of the SUMO family, conjugated t o lysine residues of target pr oteins; regulates chromatid co hesion, chromosome segregation , APC-mediated proteolysis, DN A replication and septin ring dynamics; phosphorylated at Se r2
WormBase	WBGene00004888	4.0009493637353324e-18	locus:smo-1 Small ubiquitin- related modifier status:Conf irmed UniProt:P55853 prote in_id:CCD72942.1
Stentor Coeruleus	SteCoe_19343	0.000000000000004658886145103398

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25527524: Nasir AM, Yang Q, Chalker DL, Forney JD (2015) SUMOylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila. Eukaryotic cell 14(2):170-81
2. Ref:26453653: Yang Q, Nasir AM, Coyne RS, Forney JD (2015) Depletion of UBC9 Causes Nuclear Defects during the Vegetative and Sexual Life Cycles in Tetrahymena thermophila. Eukaryotic cell 14(12):1240-52
3. Ref:16682458: Matsuda A, Forney JD (2006) The SUMO pathway is developmentally regulated and required for programmed DNA elimination in Paramecium tetraurelia. Eukaryotic cell 5(5):806-15

Sequences

>TTHERM_00410130(coding)
ATGACTGATTAAAACGCTAACGCTAACAGTGAATATCTTAATCTTAAAGTTAAATCTTAG
GAAGGAGAAGAAATTTTCTTTAAAATTAAAAAAACTACTCAATTTAAGAAACTTATGGAT
GCTTACTGTCAAAGAGCTTAAGTTAACGCCCATAATGTAAGATTCCTCTTCGATGGTGAT
AGAATCCTTGAATCTCACACCCCCGCTGATCTTAAAATGGAAAGTGGAGATGAAATCGAC
GTTGTTGTTGAACAAGTTGGTGGCTCTTTCTGA

>TTHERM_00410130(protein)
MTDQNANANSEYLNLKVKSQEGEEIFFKIKKTTQFKKLMDAYCQRAQVNAHNVRFLFDGD
RILESHTPADLKMESGDEIDVVVEQVGGSF

>TTHERM_00410130(gene)
ATGACTGATTAAAACGCTAACGCTAACAGTGAATATCTTAATCTTAAAGTTAAATCTTAG
GTAAAATATAAAATACTTATTTAAACTAGAGCCAACCGTCTTTAGCAAAACAGTTGAAGC
ATAGATTATTTACTTATATATCAATTTCTCTAAAGCAATCCTCTACTTGGAATAGCCAAT
AAATATTTGCTTAATATTCAATCTATGTAGCAAAGCCCCACAAAAATAAATTAAAATATT
TTACGAAATTTAATCTATCGATATATACGAATTTACGAAATGAAATTAACTCATTAGTAG
ACTTCAATTTATAAATCAGCTTCATAATTATTTTAAAAGCGGCTCAGTTCATTCTAAAAT
ATCTTTTATAAAATTATTCTAATAATAATAATAATAATAATAGGAAGGAGAAGAAATTTT
CTTTAAAATTAAAAAAACTACTCAATTTAAGAAACTTATGGATGCTTACTGTCAAAGAGC
TTAAGTAAAAATCTTTTTTGATAGTTTTTAATGCTAGAAATATAAATAAAATAAAATATT
ACAGAAATTTTGAAATATCATTTAAATTTGCTAATTTGTTATTATTAATTCAATTAAAGG
TTAACGCCCATAATGTAAGATTCCTCTTCGATGGTGATAGAATCCTTGAATCTCACACCC
CCGCTGATGTAATTTTTAATTTAAAAATTTAAAAATCGTGAACAACTTCAAATAAAAGCC
ATTCTTATTACAAATTTATAATATTCAATAAATAAGACTATGAAAAAATTAATTATCCTA
CTTTGAAATTTGTTTGTTTGTTTACTGTTTTTAAGCAATAAAATTTATTCAAAAGTTATG
TTAATATCTTACTTATTTAAATAAAAAATAGCTTAAAATGGAAAGTGGAGATGAAATCGA
CGTTGTTGTTGAACAAGTTGGTGGCTCTTTCTGA