Identifiers and Description

Gene Model Identifier

TTHERM_00476820

Standard Name

RVB1 (RuVB-like)

Aliases

PreTt06210 | 58.m00182 | 3719.m00042

Description

RVB1 holliday junction ATP-dependent DNA helicase RuvB; Member of the SWR complex. Homolog of yeast ATP-dependent DNA helicase RVB1- also known as pontin

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• DNA helicase activity (IEA) | GO:0003678
• ATP binding (IEA) | GO:0005524

Domains

• ( PF06068 ) TIP49 C-terminus
• ( PF00004 ) ATPase, AAA family
• ( TIGR01242 ) 26S proteasome subunit P45 family
• ( PF07728 ) ATPase family associated with various

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00476820

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_16296	0
WormBase	WBGene00007784	9.997093137033517e-262	locus:ruvb-1 status:Confirme d UniProt:O17607 protein_i d:CAB02793.2
Tetrahymena borealis	EI9_14183.1	9.997093137033517e-262	TIP49 family protein (455 aa)
DictyBase	DDB_G0293226	9.997093137033517e-262	rvb1 on chromosome: 6 position 2678243 to 2679944
Oxytricha	Contig13363.0.g11	9.997093137033517e-262	TIP49 C-terminus
SGD	YDR190C	9.997093137033517e-262	RVB1 Essential protein involve d in transcription regulation; component of chromatin remode ling complexes; required for a ssembly and function of the IN O80 complex; also referred to as pontin; member of the RUVB- like protein family

General Information

No Data fetched for General Information

Associated Literature

1. Ref:29523178: Saettone A, Garg J, Lambert JP, Nabeel-Shah S, Ponce M, Burtch A, Thuppu Mudalige C, Gingras AC, Pearlman RE, Fillingham J (2018) The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila. Epigenetics & chromatin 11(1):10

Sequences

>TTHERM_00476820(coding)
ATGAAGATCGAAGAAGTAAAATCAACCACAAAGACTTAAAGAATCGCCTCTCACTCTCAC
GTTAAGGGTTTGGGTTTAAATGAAGAAGGTACTGCTGTTGCAGTCGCTTCTGGTATGGTC
GGCCAAGAAAATGCTAGAGAAGCTGCTGGTGTTGTTGTTGAATTAATTAAAACAAAGAAA
ATGGCTGGTAGAGCTGTCCTCTTAGCTGGTCCTCCCGGAACTGGTAAGACTGCTATCTCA
CTTGCCATTTCTTCTGAATTAGGTCCTAAAGTTCCATTCTGCCCAATGGTCGGTTCTGAA
GTTTACTCCACAGAAGTTAAGAAAACTGAAATTCTTATGGAAAACTTCCGTAGAGCAATT
GGTTTAAAGATTAAAGAAACAAAGGAAGTCTGGGAAGGAGAAGTCACTGAACTTAAGACT
GAAGAAAGAGAAGAAGCTTAAGGATACGGTAAAATAGTTAGCAGTGTCATTGTTACTTTG
AAGACTTCTAAAGGTACCAAGCAATTAAAGTTAGATCCTTCTATTTATGAAAATATGCAA
AGAGAAAAAGTTAGTGTTGGTGATGTTATCTACATTGAAGCTTCAAGTGGTAATGTCAAA
AGAGTTGGTAGATGTGACGCTTATGCTTCTGAGTATGATTTAGAAGCTGAAGAATATGTC
CCCTTACCAAAGGGTGATGTACACAAGAAGAAAGAAATTGTGTAAGATATTACTCTCCAT
GACTTGGACGTTGCCAATGCTCGTCCTCAACACGGCTAAGACTTTGTTTCTCTTATGGGT
CAAATCATGAAACCAAAAAAGACTGAAATTACTGAAAAGTTACGTCAATAAATCAACTAA
ATCGTTAATAAATATATTGACTAAGGTATTGCTGAACTTGTCCCTGGTGTGCTCTTTATT
GATGAAGTCCACATGCTTGATATTGAATGTTTCACTTATCTTAACAGAGCCTTAGAATCA
ACTCTTGCTCCTATTGTTATTCTTGCTACCAACAGAGGTATGTGCACCATTAGAGGAACT
GACATAGTATCTCCTCATGGTATTCCTATTGATTTGTTGGACAGACTTTTGATTATCAAG
ACTGTTCCTTACGGATTAGAAGATTTAATTAAAATTCTTGCTATCAGAGCTTCAACTGAA
AGCATCAAATTATCCACTGAAGCTTTATCATTTTTAGGTCAAGTAGGTAGCTCCTCTTCT
CTCAGATATGCAGTTCAACTTTTAACTCCTGCAAGTGTTTTAGCTCAAACAGAAGGAAGA
ACCGAAATTACTAAGGAAGATATTGAAGTTATTAATAAATTATTCTTAGATGCTAAATCT
TCTGCTAAATTATTAAATGAACAAGCAGAAAAGTATATCAGTTGA

>TTHERM_00476820(protein)
MKIEEVKSTTKTQRIASHSHVKGLGLNEEGTAVAVASGMVGQENAREAAGVVVELIKTKK
MAGRAVLLAGPPGTGKTAISLAISSELGPKVPFCPMVGSEVYSTEVKKTEILMENFRRAI
GLKIKETKEVWEGEVTELKTEEREEAQGYGKIVSSVIVTLKTSKGTKQLKLDPSIYENMQ
REKVSVGDVIYIEASSGNVKRVGRCDAYASEYDLEAEEYVPLPKGDVHKKKEIVQDITLH
DLDVANARPQHGQDFVSLMGQIMKPKKTEITEKLRQQINQIVNKYIDQGIAELVPGVLFI
DEVHMLDIECFTYLNRALESTLAPIVILATNRGMCTIRGTDIVSPHGIPIDLLDRLLIIK
TVPYGLEDLIKILAIRASTESIKLSTEALSFLGQVGSSSSLRYAVQLLTPASVLAQTEGR
TEITKEDIEVINKLFLDAKSSAKLLNEQAEKYIS

>TTHERM_00476820(gene)
ATGAAGGTATAAAATAAAATTAATTTATTTGATAAATAAAAATTTAAAGAAATGTGCTGA
GAAAATAAATTTGTTAGTTTTGTAAACTGAAAAATTCTTCAAAAAATAAATACTCCATAA
GCATTTCTTTAAATAGTGAAAATATTTTTGCAGTCGCTCAATGTATTTTAACTAATACTT
TTATTTTATAGATCGAAGAAGTAAAATCAACCACAAAGACTTAAAGAATCGCCTCTCACT
CTCACGTTAAGGGTTTGGGTTTAAATGAAGAAGGTACTGCTGTTGCAGTCGCTTCTGGTA
TGGTCGGCCAAGAAAATGCTAGAGAAGTAATTTAATATTAATTGATAGTTTTAGTATTTA
ATAAAAGCTTAATCCATGTTTCATCTAAAAAATAGAAAAATATAAATTTTCAATATTTCT
ATTTTATAAAATAAACAAGTTATTAAATAAGTTATCAAAAATATGTCTTAAATGAAATAT
AATTTAATGTAAAAAGCATACATCAAACTACATTTAAATGCTTATCTAAGTAGCAAGTGA
TATATTGATTAATTACATTTTTATTATTATAGGCTGCTGGTGTTGTTGTTGAATTAATTA
AAACAAAGAAAATGGCTGGTAGAGCTGTCCTCTTAGCTGGTCCTCCCGGAACTGGTAAGA
CTGCTATCTCACTTGCCATTTCTTCTGAATTAGGTCCTAAAGTTCCATTCTGCCCAATGG
TCGGTTCTGAAGTTTACTCCACAGAAGTTAAGAAAACTGAAATTCTTATGGAAAACTTCC
GTAGAGCAATTGGTTTAAAGATTAAAGAAACAAAGGAAGTCTGGGAAGGAGAAGTCACTG
AACTTAAGACTGAAGAAAGAGAAGAAGCTTAAGGGTATTTTTTTTGTTAATAATTTATAA
GATTAAGAAAAAATAGTGAAGAATACAAATAAATATTTTAACTTGCAAAAAAAATGCAAT
TAAATTTATGAGTGTCTATTTAAAGTTAAAATGAATTTATGTATGATTGCATTTTTAAAT
GGAAGCTCATTTAATTTTAAAATAATTGAAAATAAGTTGTTAAGAAAATTGATTTTATTA
ATAATATTTTTAATAAATTAGATACGGTAAAATAGTTAGCAGTGTCATTGTTACTTTGAA
GACTTCTAAAGGTACCAAGCAATTAAAGTTAGATCCTTCTATTTATGAAAATATGCAAAG
AGAAAAAGTTAGTGTTGGTGATGTTATCTACATTGAAGCTTCAAGTGGTAATGTCAAAAG
AGTTGGTAGATGTGACGCTTATGCTTCTGAGTATGATTTAGAAGCTGAAGAATATGTCCC
CTTACCAAAGGGTGATGTACACAAGAAGAAAGAAATTGTGTAAGATATTACTCTCCATGA
CTTGGACGTTGCCAATGCTCGTCCTCAACACGGCTAAGACTTTGTTTCTCTTATGGGTCA
AATCATGAAACCAAAAAAGACTGAAATTACTGAAAAGTTACGTCAATAAATCAACTAAAT
CGTTAATAAATATATTGACTAAGGTATTGCTGAACTTGTCCCTGGTGTGCTCTTTATTGA
TGAAGTCCACATGCTTGATATTGAATGTTTCACTTATCTTAACAGAGCCTTAGAATCAAC
TCTTGCTCCTATTGTTATTCTTGCTACCAACAGAGGTATGTGCACCATTAGAGGAACTGA
CATAGTATCTCCTCATGGTATTCCTATTGATTTGTTGGACAGGTAATCACTATACTAACT
ATTTATCTTTAATCACATTGCTCTCCTTATCAATTTAATTAATAAATTTTTTTTTTTAAT
AGACTTTTGATTATCAAGACTGTTCCTTACGGATTAGAAGATTTAATTAAAATTCTTGCT
ATCAGAGCTTCAACTGAAAGCATCAAATTATCCACTGAAGCTTTATCATTTTTAGGTCAA
GTAGGTAGCTCCTCTTCTCTCAGATATGCAGTTCAACTTTTAACTCCTGCAAGTGTTTTA
GCTCAAACAGAAGGAAGAACCGAAATTACTAAGTAAATTATTAGTTTTTATTCTAATTTT
GCTAAATAAAATTTCTTGTAAAAATAAAGGGAAGATATTGAAGTTATTAATAAATTATTC
TTAGATGCTAAATCTTCTGCTAAATTATTAAATGAACAAGCAGAAAAGTATATCAGTTGA