Identifiers and Description

Gene Model Identifier

TTHERM_01122740

Standard Name

RRP64 (exosome component RRP6-4)

Aliases

PreTt24593 | 243.m00042

Description

RRP64 3-prime-5-prime exonuclease

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• 3'-5' exonuclease activity (IEA) | GO:0008408
• nucleic acid binding (IEA) | GO:0003676

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

• ( PF00570 ) HRDC domain
• ( TIGR01388 ) ribonuclease D
• ( PF01612 ) 3'-5' exonuclease
• ( PF08066 ) PMC2NT (NUC016) domain
• ( TIGR00377 ) anti-anti-sigma factor

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_01122740

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_10594.1	9.997093137033517e-262	3-5 exonuclease (879 aa)
DictyBase	DDB_G0271572	2.000383902553626e-98	exosc10 on chromosome: 2 posit ion 601251 to 605014
Oxytricha	Contig14024.0.g55	5.001102406662288e-90	3-5 exonuclease
SGD	YOR001W	1.9996609186508915e-82	RRP6 Nuclear exosome exonuclea se component; has 3-5 exonucle ase activity; involved in RNA processing, maturation, survei llance, degradation, tethering , and export; has similarity t o E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-base d run-on (GLRO) assay
WormBase	WBGene00000796	4.000989088096131e-71	locus:crn-3 status:Confirmed UniProt:G5EBX6 protein_id :CAA90108.1
Stentor Coeruleus	SteCoe_9214	8.194012623990515e-40

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01122740(coding)
ATGGCTAGCAATAATAAAATTAAGGATTTAGATGAAATTCTTAACTAAAAGGATTTCATG
AAGTAGGTTTTGTAGAAAGATGCAAGTCTTGTTCGTTTGAGTAACTCTCTTCCATAAAAT
GATGAAATGAAGTTTTACATGAACAATGAGCAACTAAAATAAAAGCAAAAGGCTATCAAT
GTTAAAATTCTCCACCAGTTAAAGAAAATAGCATCATTTATATAATTTGAGCAAGCTTCT
AGCATTGACTTAAACCATTTTAGCCATATCATAGACATGAATGATCTACTTTTTGAGAAT
ATCGACACTTCATTGGACAAAATTAAAAAAATTAATAATGTCACTGAGTCTTCTCTTTTC
GATCCTTCTAAGACTATATCCTCTGACAAGGGCTTCAAGCCTATTAGTGGGGAGGAATCC
GAAGACATAATCACAATAGCAACAAAAGAAAAACCTTAAAACCATTTTAAAGATTGCATT
GATAATTCAATAGAACATCCTTTCATTCCTGTCATCAAAGAAAAGCTAAATGCAGATGTT
CCATTAGATGATGTCATAGTTTAAGTATAGAGAGAGGGAGCTGAAAGCTTTTTTAAAACC
ATTTAAGACCCTTTATAATATGAATTTCCCCACCCTTATGCTTATGAAATTGAGAATTTC
AATTTCTCAGAGTAACAATTACAGACAGATAATATAATAGTTTAGGAGCCTATTAGTCTT
AAAGAGGAGTTAGTGTTTGTAGATAAAGAAGATATTTTAGACGAAATGATAGAGTCTCTG
AAGTAATGTAGCGAAGTAGCTATTGATTTAGAACACCATTCATATCGTTCATTCAACGGT
ATTACTTGCTTGATGCAGATTTCTAGCAGAACTAAAGACTACATTGTGGATGTCTTCAGT
GTATGGAAATCTCTACATAAGCTTAATGCAGTTACTACAGATAAAAATATTGTTAAAGTT
CTTCATGGTGCAGATATGGATATTCAATGGTTACAAAGAGATTTTGGAATTTATATTGTT
AATTTATTCGATACCGGATAAGCAGCCAGAACTTTATCTATGCCCAGCTATGCATTAGCT
TATCTTTTATAATCTATTTCAAAAGTACCCACAGATAAAAAGTACCAATTAGCTGATTGG
AGAATCCGTCCTCTCCCAAGAGAAATGATAAGTTATGCTAGATCAGATACACACTATTTG
TTATCAATTTATGACAATTTAAGAATTCAACTTGTAAGCAAAGCACTTTAGTAAGGATAA
AATGCTTCTCACTTTATTGAGAGTGTTCTGAATAAGTCTAGAGCTATTTGCCTCAAAAAG
TATGTCAAGCCAATTTTAGATGATGAAAAATATCACTCAATTTTACAAAATTAACGTATC
ATCTTATCTGACAGAAAGTTCCGCATTTTAAAAAGACTCCTCGAATGGAGATATAAAATG
GCTGCTAAATATGATGAAAATCCTACCTTTGTTTTAGCTAATGATATTCTTTTCAATATT
GTAAATAGACTACCCTAAACTCAGAAAGAGTTTGCATCTTCAAATCTTAAGCTTAGTTAC
GTATGCCAATATCATGCAAACGAAATTCTTTCTATTATTAAGGAAGAAATTGAATCTGAA
CAAAAGTCTAAATCTGGAGAATCAGAGAGTGCCACCAAAAATTAAAGTGAAATGGAAACT
GAAGATCTGATTTATGCCTCTCGTAACCATAATAATAACATATCAGGATACTAAATAATT
AACACTCAGAGTCACCAAATGGAGTAGGAGCTTGAAGATGAAGAGGTTTCCTTCAAATTT
GAAGTAATTGATGTATAAATTGGGGTGTATTAAGGCAATTTGAATATTTTAGAAGACCAC
ATACTATCATCTTCAACCTCTGCTGAAATATAATCAAAAATAGATAAAATTAATTCTTCT
TTCTTCTATGCAGATCCTGTAGATTTTTATTGCGAAAAATACCCTTTTATGAGAGAAGCT
TATGAACTCGCTAAATTGCAAGAAGAAGAAATTATGAAAAAAAGAAATGACCTGGCCTAC
ATTTAGAGTAAAAACCCATTTGAAGGTGAAAACGAAGGACAAACTAACAAGGAAGAAGAA
GAAAGAGATATTTATTTAGCATTTGATAAGGAAAAAGGACCTTCTTCTAAACCAAAAGAA
GTTGAACAAATAAATGTGCCTGATTTACCTCAATCTTATGAAGATTAGTTTAAAACAAGT
CTCAAAAAGAGAAAATATAATTTTGGCAATGAAGCAAAAAGAAACAACAACTAAGATGAA
GAGGGAGAAGAAGATAATGAAAATGGAGAAAAAATTTACAAAAAAAGATCTACTGGATAA
AAAAGTACATTCGATATGTTAATAGAGTAAGGTCTCAGAGAACAAACTGACTCTGAAGAA
TCAGATTCTGAAGAAGGTGAATAATAGTAGAAGAAGAAAAAAAGAGAGGTTACAGAAGAA
GAAAAAAAACAAATCGAAGATAATTTTAACCAGTTTGCAGATAAAATAAGAAATAGAATC
AATAAAGATCCTAAGTTTAAATCTGGTATCAATGCATAAAAAAAATTCAACAGTAGCAAT
AATAAAAAGGGTGGTAATAAAAAAAATAATAAGTTTATAAGCAAGTTCAACAAAAGCGGA
TTTTGA

>TTHERM_01122740(protein)
MASNNKIKDLDEILNQKDFMKQVLQKDASLVRLSNSLPQNDEMKFYMNNEQLKQKQKAIN
VKILHQLKKIASFIQFEQASSIDLNHFSHIIDMNDLLFENIDTSLDKIKKINNVTESSLF
DPSKTISSDKGFKPISGEESEDIITIATKEKPQNHFKDCIDNSIEHPFIPVIKEKLNADV
PLDDVIVQVQREGAESFFKTIQDPLQYEFPHPYAYEIENFNFSEQQLQTDNIIVQEPISL
KEELVFVDKEDILDEMIESLKQCSEVAIDLEHHSYRSFNGITCLMQISSRTKDYIVDVFS
VWKSLHKLNAVTTDKNIVKVLHGADMDIQWLQRDFGIYIVNLFDTGQAARTLSMPSYALA
YLLQSISKVPTDKKYQLADWRIRPLPREMISYARSDTHYLLSIYDNLRIQLVSKALQQGQ
NASHFIESVLNKSRAICLKKYVKPILDDEKYHSILQNQRIILSDRKFRILKRLLEWRYKM
AAKYDENPTFVLANDILFNIVNRLPQTQKEFASSNLKLSYVCQYHANEILSIIKEEIESE
QKSKSGESESATKNQSEMETEDLIYASRNHNNNISGYQIINTQSHQMEQELEDEEVSFKF
EVIDVQIGVYQGNLNILEDHILSSSTSAEIQSKIDKINSSFFYADPVDFYCEKYPFMREA
YELAKLQEEEIMKKRNDLAYIQSKNPFEGENEGQTNKEEEERDIYLAFDKEKGPSSKPKE
VEQINVPDLPQSYEDQFKTSLKKRKYNFGNEAKRNNNQDEEGEEDNENGEKIYKKRSTGQ
KSTFDMLIEQGLREQTDSEESDSEEGEQQQKKKKREVTEEEKKQIEDNFNQFADKIRNRI
NKDPKFKSGINAQKKFNSSNNKKGGNKKNNKFISKFNKSGF

>TTHERM_01122740(gene)
ATGGCTAGCAATAATAAAATTAAGGATTTAGATGAAATTCTTAACTAAAAGGATTTCATG
AAGTAGGTTTTGTAGAAAGATGCAAGTCTTGTTCGTTTGAGTAACTCTCTTCCATAAAAT
GATGAAATGAAGTTTTACATGAACAATGAGCAACTAAAATAAAAGCAAAAGGCTATCAAT
GTTAAAATTCTCCACCAGTTAAAGAAAATAGCATCATTTATATAATTTGAGCAAGCTTCT
AGCATTGACTTAAACCATTTTAGCCATATCATAGACATGAATGATCTACTTTTTGAGAAT
ATCGACACTTCATTGGACAAAATTAAAAAAATTAATAATGTCACTGAGTCTTCTCTTTTC
GATCCTTCTAAGACTATATCCTCTGACAAGGGCTTCAAGCCTATTAGTGGGGAGGAATCC
GAAGACATAATCACAATAGCAACAAAAGAAAAACCTTAAAACCATTTTAAAGATTGCATT
GATAATTCAATAGAACATCCTTTCATTCCTGTCATCAAAGAAAAGCTAAATGCAGATGTT
CCATTAGATGATGTCATAGTTTAAGTATAGAGAGAGGGAGCTGAAAGCTTTTTTAAAACC
ATTTAAGACCCTTTATAATATGAATTTCCCCACCCTTATGCTTATGAAATTGAGAATTTC
AATTTCTCAGAGTAACAATTACAGACAGATAATATAATAGTTTAGGAGCCTATTAGTCTT
AAAGAGGAGTTAGTGTTTGTAGATAAAGAAGATATTTTAGACGAAATGATAGAGTCTCTG
AAGTAATGTAGCGAAGTAGCTATTGATTTAGAACACCATTCATATCGTTCATTCAACGGT
ATTACTTGCTTGATGCAGATTTCTAGCAGAACTAAAGACTACATTGTGGATGTCTTCAGT
GTATGGAAATCTCTACATAAGCTTAATGCAGTTACTACAGATAAAAATATTGTTAAAGTT
CTTCATGGTGCAGATATGGATATTCAATGGTTACAAAGAGATTTTGGAATTTATATTGTT
AATTTATTCGATACCGGATAAGCAGCCAGAACTTTATCTATGCCCAGCTATGCATTAGCT
TATCTTTTATAATCTATTTCAAAAGTACCCACAGATAAAAAGTACCAATTAGCTGATTGG
AGAATCCGTCCTCTCCCAAGAGAAATGATAAGTTATGCTAGATCAGATACACACTATTTG
TTATCAATTTATGACAATTTAAGAATTCAACTTGTAAGCAAAGCACTTTAGTAAGGATAA
AATGCTTCTCACTTTATTGAGAGTGTTCTGAATAAGTCTAGAGCTATTTGCCTCAAAAAG
TATGTCAAGCCAATTTTAGATGATGAAAAATATCACTCAATTTTACAAAATTAACGTATC
ATCTTATCTGACAGAAAGTTCCGCATTTTAAAAAGACTCCTCGAATGGAGATATAAAATG
GCTGCTAAATATGATGAAAATCCTACCTTTGTTTTAGCTAATGATATTCTTTTCAATATT
GTAAATAGACTACCCTAAACTCAGAAAGAGTTTGCATCTTCAAATCTTAAGCTTAGTTAC
GTATGCCAATATCATGCAAACGAAATTCTTTCTATTATTAAGGAAGAAATTGAATCTGAA
CAAAAGTCTAAATCTGGAGAATCAGAGAGTGCCACCAAAAATTAAAGTGAAATGGAAACT
GAAGATCTGATTTATGCCTCTCGTAACCATAATAATAACATATCAGGATACTAAATAATT
AACACTCAGAGTCACCAAATGGAGTAGGAGCTTGAAGATGAAGAGGTTTCCTTCAAATTT
GAAGTAATTGATGTATAAATTGGGGTGTATTAAGGCAATTTGAATATTTTAGAAGACCAC
ATACTATCATCTTCAACCTCTGCTGAAATATAATCAAAAATAGATAAAATTAATTCTTCT
TTCTTCTATGCAGATCCTGTAGATTTTTATTGCGAAAAATACCCTTTTATGAGAGAAGCT
TATGAACTCGCTAAATTGCAAGAAGAAGAAATTATGAAAAAAAGAAATGACCTGGCCTAC
ATTTAGAGTAAAAACCCATTTGAAGGTGAAAACGAAGGACAAACTAACAAGGAAGAAGAA
GAAAGAGATATTTATTTAGCATTTGATAAGGAAAAAGGACCTTCTTCTAAACCAAAAGAA
GTTGAACAAATAAATGTGCCTGATTTACCTCAATCTTATGAAGATTAGTTTAAAACAAGT
CTCAAAAAGAGAAAATATAATTTTGGCAATGAAGCAAAAAGAAACAACAACTAAGATGAA
GAGGGAGAAGAAGATAATGAAAATGGAGAAAAAATTTACAAAAAAAGATCTACTGGATAA
AAAAGTACATTCGATATGTTAATAGAGTAAGGTCTCAGAGAACAAACTGACTCTGAAGAA
TCAGATTCTGAAGAAGGTGAATAATAGTAGAAGAAGAAAAAAAGAGAGGTTACAGAAGAA
GAAAAAAAACAAATCGAAGATAATTTTAACCAGTTTGCAGATAAAATAAGAAATAGAATC
AATAAAGATCCTAAGTTTAAATCTGGTATCAATGCATAAAAAAAATTCAACAGTAGCAAT
AATAAAAAGGGTGGTAATAAAAAAAATAATAAGTTTATAAGCAAGTTCAACAAAAGCGGA
TTTTGA