Identifiers and Description

Gene Model Identifier

TTHERM_00630440

Standard Name

RRP63 (exosome component RRP6-3)

Aliases

PreTt06557 | 89.m00151 | 3831.m01452

Description

RRP63 3-prime-5-prime exonuclease

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• 3'-5' exonuclease activity (IEA) | GO:0008408
• nucleic acid binding (IEA) | GO:0003676

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00630440

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_04332.1	9.997093137033517e-262	3-5 exonuclease (506 aa)
Oxytricha	Contig8740.0.1.g10	3.00017180903994e-49	3-5 exonuclease
Stentor Coeruleus	SteCoe_7112	2.031092662734811e-42
DictyBase	DDB_G0278079	2.0003218023735366e-33	exdl2A on chromosome: 3 positi on 242964 to 245120
SGD	YOR001W	2.000470901975128e-28	RRP6 Nuclear exosome exonuclea se component; has 3-5 exonucle ase activity; involved in RNA processing, maturation, survei llance, degradation, tethering , and export; has similarity t o E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-base d run-on (GLRO) assay
WormBase	WBGene00000796	4.9988726541653934e-26	locus:crn-3 status:Confirmed UniProt:G5EBX6 protein_id :CAA90108.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00630440(coding)
ATGAGTGTTAAAAATAAGTATAATATATAAGACTTCGTAAATTCAAACTATTGTGAAACT
AAACCATTTTATAATGGTTAATATATTTTAGTTTAAACAAAAGAGCAACTCCGCGAATGC
ATTTAAGAGATCAAACAGTTTAACAAAATAGGAGTTGATACAGAATAGAGCTTCATGCAG
ACTTATTAGGCCTTTCTTTGTTTAATTTAAATATCTACTGAAGAGAAAGATTATCTGATT
GATTTACTCTCAATAAATGACAAATAATATATTAAGTCAGAGATTGAGTAAATATTCCTG
GATAAAAATATAATTAAAATTTTTTATGCAGGATAAACTGATATCGTATGGCTATAAAGA
GACTATGATATTTTAATATCTAACTATTTTGATATTTAAACTGCTGCAATATTTTTAAAT
AAGGATGAAAGCTGGTCTTTAACTTATCTTCTTTAAAAATACTGCGACTATACTCTTGAA
AAGAAAGAGAAGAAATAACTTTAACTTTCAGAATGGTCTGATCGCCCACTAAGTGAAGAA
TAATTAAATTATGCAGCTCTCGACTCTCATTTCTTAATAAAAATAAGATACGAGCTACTT
CACGAAATGATCAAAAGACTGGATTTCTAAAGAACACTAGAACTTCTTTACAAAATGCAG
AAAGCTACATCTAAAAAATATGAGAAAAAGCCATTTGATGAGTTATTTTACTTCTAAGCT
TTCGAAAAGTAATCTAAAATTTAGGTTAATAGTATTGGAGCTGGGCTTAAGAGTACAACA
GAATGGAAAATTCTTAATATAATTTTCTTAGAACTTGCAGAATTGAGAGAGAGTTACTCT
GAATAGTAAAATAGATATATTCAAAGTGTTTTAACAGAAGAATCATTGCTGCAAATAGCT
TATTCTACCTTTGATGAAATATAATATAAATTAAAAAGTGTATACGAAATTCAAAACTAA
GACTAATTTACTGAAAAGCATTCTTAAGATTTCTTGAATTCAAATAAGGAGAAAATAATT
TCAATTCTAAATAGACACACAATTGAATTAGATAAAATTATTGAGAAATACGAATTGCTA
TGCATACCAATTAAAAATAAAATGCATATCCTTCAGCAAAGAATTGAGAGGAAAAATAAG
ACATTCTAAGAAAAATACTCGATGAAGACTGTACCTTACGAAAACTGCTAAATACTTTCA
CCAGATGGACAGCAATTATGTAACTGTAACAGTAAAAAAATTTAATGGTATCTTAAGAAA
GGGTTAGCTCATCTTGTAAGCGAAAATCCTACAGTTATCAAACTTAACTTCTAGCCAAGT
GGAAAGGGAAATTTTGATTTGGAGGATTAGAAGATCTTTGAAAACAATTACTATTATGTA
ACAGAAAGAGAAAACAAATGTGTTGTCTGTGGTTCTACAGAAAAATTTGCTAAATTTTAC
GTTATTCCATCTCTCTATAGGCGTCATTTTCCAGATATTTTGAAGAGTCATAGATCTTAG
GATATACTGCTTTTGTGTATGAATTGCCATCAAAGAGCAGGAACTTACTGTGATAAAAAG
ATTGACGAAATTTGTTAGTAATATCAAGTTGATAAAATTAGTTTGTAGTATGCTTCAGTG
GTGTAAGACGTTATCTAAAGATTGAGCAGGAGTGCTAGGTCTTTCCAGAAAAATAAGTCT
CATATGCCCAAAGAGAATAAGAAGAAACTAAAATCAATAATTAGATAGAACTATTAGGAT
TTTATAGAGTTAAAGGATATTCAATAAAAGATAGATATTCACCCTGATTCTTATTTTGGA
ATTAACAAGTAAAATTAAATTAAGATTAATGATAAGTTTATATCATATTGCTTGGAAATT
GATAACTTTAAAAAAATTGGTAAAGAGAATTCATGTAATGATTTTAAGAATTAGCATGGT
AAATATGTAGTAGAATAACTTAAAAACTTAAAAGATCTTACTGAATTTGTTCTTATGTGG
CGTTAGTATTTCATTAAAACAATGTAGCCTAAATATTTACCAAGAGATTGGACAGAAAAG
CCTAAAAGAGTAGAACCAGATAACGAAAGTAAATATGATAAAAAGCTTGAATAGATTCAA
ATATTTTCAAACTAATGA

>TTHERM_00630440(protein)
MSVKNKYNIQDFVNSNYCETKPFYNGQYILVQTKEQLRECIQEIKQFNKIGVDTEQSFMQ
TYQAFLCLIQISTEEKDYLIDLLSINDKQYIKSEIEQIFLDKNIIKIFYAGQTDIVWLQR
DYDILISNYFDIQTAAIFLNKDESWSLTYLLQKYCDYTLEKKEKKQLQLSEWSDRPLSEE
QLNYAALDSHFLIKIRYELLHEMIKRLDFQRTLELLYKMQKATSKKYEKKPFDELFYFQA
FEKQSKIQVNSIGAGLKSTTEWKILNIIFLELAELRESYSEQQNRYIQSVLTEESLLQIA
YSTFDEIQYKLKSVYEIQNQDQFTEKHSQDFLNSNKEKIISILNRHTIELDKIIEKYELL
CIPIKNKMHILQQRIERKNKTFQEKYSMKTVPYENCQILSPDGQQLCNCNSKKIQWYLKK
GLAHLVSENPTVIKLNFQPSGKGNFDLEDQKIFENNYYYVTERENKCVVCGSTEKFAKFY
VIPSLYRRHFPDILKSHRSQDILLLCMNCHQRAGTYCDKKIDEICQQYQVDKISLQYASV
VQDVIQRLSRSARSFQKNKSHMPKENKKKLKSIIRQNYQDFIELKDIQQKIDIHPDSYFG
INKQNQIKINDKFISYCLEIDNFKKIGKENSCNDFKNQHGKYVVEQLKNLKDLTEFVLMW
RQYFIKTMQPKYLPRDWTEKPKRVEPDNESKYDKKLEQIQIFSNQ

>TTHERM_00630440(gene)
ATGAGTGTTAAAAATAAGTATAATATATAAGACTTCGTAAATTCAAACTATTGTGAAACT
AAACCATTTTATAATGGTTAATATATTTTAGTTTAAACAAAAGAGCAACTCCGCGAATGC
ATTTAAGAGATCAAACAGTTTAACAAAATAGGTATTATTTAAAAATTTTTTTTACCAATC
ATTCAATAAATCATTAAAAATATTTATATATTTATTTATTTATTAATTATAAAAGGAGTT
GATACAGAATAGAGCTTCATGCAGACTTATTAGGCCTTTCTTTGTTTAATTTAAATATCT
ACTGAAGAGAAAGATTATCTGATTGATTTACTCTCAATAAATGACAAATAATATATTAAG
TCAGAGATTGAGTAAATATTCCTGGATAAAAATATAATTAAAATTTTTTATGCAGGATAA
ACTGATATCGTATGGCTATAAAGAGACTATGATATTTTAATATCTAACTATTTTGATATT
TAAACTGCTGCAATATTTTTAAATAAGGATGAAAGCTGGTCTTTAACTTATCTTCTTTAA
AAATACTGCGACTATACTCTTGAAAAGAAAGAGAAGAAATAACTTTAAGTAGAATTTCTT
TATTTGTTTATTTGTTTTATTAACTTCTATTTTTAATTGTTGATAAAAATTAGCTTTCAG
AATGGTCTGATCGCCCACTAAGTGAAGAATAATTAAATTATGCAGCTCTCGACTCTCATT
TCTTAATAAAAATAAGATACGAGCTACTTCACGAAATGATCAAAAGACTGGATTTCTAAA
GAACACTAGAACTTCTTTACAAAATGCAGAAAGCTACATCTAAAAAATATGAGAAAAAGC
CATTTGATGAGTTATTTTACTTCTAAGCTTTCGAAAAGTAATCTAAAATTTAGGTTAATA
GTATTGGAGCTGGGCTTAAGAGTACAACAGAATGGAAAATTCTTAATATAATTTTCTTAG
AACTTGCAGAATTGAGAGAGAGTTACTCTGAATAGTAAAATAGATATATTCAAAGTGTTT
TAACAGAAGAATCATTGCTGCAAATAGCTTATTCTACCTTTGATGAAATATAATATAAAT
TAAAAAGTGTATACGAAATTCAAAACTAAGACTAATTTACTGAAAAGCATTCTTAAGATT
TCTTGAATTCAAATAAGGAGAAAATAATTTCAATTCTAAATAGACACACAATTGAATTAG
ATAAAATTATTGAGAAATACGAATTGCTATGCATACCAATTAAAAATAAAATGCATATCC
TTCAGCAAAGAATTGAGAGGAAAAATAAGACATTCTAAGAAAAATACTCGATGAAGACTG
TACCTTACGAAAACTGCTAAATACTTTCACCAGATGGACAGCAATTATGTAACTGTAACA
GTAAAAAAATTTAATGGTATCTTAAGAAAGGGTTAGCTCATCTTGTAAGCGAAAATCCTA
CAGTTATCAAACTTAACTTCTAGCCAAGTGGAAAGGGAAATTTTGATTTGGAGGATTAGA
AGATCTTTGAAAACAATTACTATTATGTAACAGAAAGAGAAAACAAATGTGTTGTCTGTG
GTTCTACAGAAAAATTTGCTAAATTTTACGTTATTCCATCTCTCTATAGGCGTCATTTTC
CAGATATGTAACAAATCAATTTCACAAAAATTTTTGTTTCACCTTTAATAAATTATTTGC
AATGAGGTTTTATTTAATTAAAAATTATATTAATTAAATTTAGAAATACTGTAATTTTTA
TACACTTCCCTCCTCCATGAACCCTCCTAATTTTTTATCTATAAAGGCTAAACAAGCCAT
TAAATTTTAAAATTTAAAGAAAATGGAAGGGCTAAAACTAGAATAATTACAGTACTTAGA
ACTTTAAATTTTAATTGAAAATAAAAAAAATAATTGAAAGTATTCAATAGTTTAATGAAG
GACTATTCAAACATGAAATATATTTTACAAATCAAATAAAATTAAAATAAATTTTTGAAT
ATAAAAAAATTAGTTTGAAGAGTCATAGATCTTAGGATATACTGCTTTTGTGTATGAATT
GCCATCAAAGAGCAGGAACTTACTGTGATAAAAAGATTGACGAAATTTGTTAGTAATATC
AAGTTGATAAAATTAGTTTGTAGTATGCTTCAGTGGTGTAAGACGTTATCTAAAGATTGA
GCAGGAGTGCTAGGTCTTTCCAGAAAAATAAGTCTCATATGCCCAAAGAGAATAAGAAGA
AACTAAAATCAATAATTAGATAGAACTATTAGGATTTTATAGAGTTAAAGGATATTCAAT
AAAAGATAGATATTCACCCTGATTCTTATTTTGGAATTAACAAGTAAAATTAAATTAAGA
TTAATGATAAGTTTATATCATATTGCTTGGAAATTGATAACTTTAAAAAAATTGGTAAAG
AGAATTCATGTAATGATTTTAAGAATTAGCATGGTAAATATGTAGTAGAATAACTTAAAA
ACTTAAAAGATCTTACTGAATTTGTTCTTATGTGGCGTTAGTATTTCATTAAAACAATGT
AGCCTAAATATTTACCAAGAGATTGGACAGAAAAGCCTAAAAGAGTAGAACCAGATAACG
AAAGTAAATATGATAAAAAGCTTGAATAGATTCAAATATTTTCAAACTAATGA