Identifiers and Description

Gene Model Identifier

TTHERM_00630430

Standard Name

RRP62 (exosome component RRP6-2)

Aliases

PreTt06556 | 89.m00150 | 3831.m01451

Description

3'-5' exonuclease family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• 3'-5' exonuclease activity (IEA) | GO:0008408
• nucleic acid binding (IEA) | GO:0003676

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.7%

TetraMine Data

TTHERM_00630430

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_04330.1	9.997093137033517e-262	3-5 exonuclease (729 aa)
Oxytricha	Contig8740.0.1.g10	1.9998745702418095e-48	3-5 exonuclease
Stentor Coeruleus	SteCoe_7112	8.985825944049381e-37
DictyBase	DDB_G0278593	3.000842737734004e-34	exdl2B on chromosome: 3 positi on 240471 to 242531
SGD	YOR001W	4.998021988471165e-24	RRP6 Nuclear exosome exonuclea se component; has 3-5 exonucle ase activity; involved in RNA processing, maturation, survei llance, degradation, tethering , and export; has similarity t o E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-base d run-on (GLRO) assay
WormBase	WBGene00000796	8.000124778438792e-23	locus:crn-3 status:Confirmed UniProt:G5EBX6 protein_id :CAA90108.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00630430(coding)
ATGAAAAATTACACAATTAAAGAGTTTTAACAATATAATCACAGTGTATTAAATCCCTTT
TAGCCTGAAAAGTATATTTTGATAGATACTTTAAATAAGCTGCAGGATTTAATTCCAATA
CTTTTAGAATAAACTAGGTTAGGAATAGATACAGAATAGAGCTTTGCCAAGACCTATGAA
GGATTTTTATGCTTGATACAAATTTCAACTGATTAAAATGACTATCTGATAGATGTTTTA
GGCATCAACAGCAAATAAGGAATTAATGAGTGTCTTTCTAAAGTTTTTTTGTGCAAAGAC
ATTATTAAAATTTTTTATGCTGGATAATAAGATATTTTATGGCTTAAGAGAGATTTTGAT
TTATCAGTAGTAAATTACTTCGATGTAAAAGAATGTGCAAGCTTCCTAAAAAAATCTGAT
GATAATTCACTTATTTAGCTGATTGATCGCTATTGCAATTACAAATTAGATAAGCAAAAG
AAAAAAGAGCTATAAGTTTCAGAGTGGTCAAATAGACCTTTAAGCAAAGAATAGTTAGAC
TATGCTGCTTTGGATTCTCATTACTTAATAAAAATTAGATATGAACTGTTGTGTGAGACT
ATATAAAGTGTCGGTTTTAAGAGAACTATTGAAGTCATTAACTAAATGCAGTAATAAACT
TTAAAGAAATATGAAAAGAAGAAGTTTGATTATTAGTACTTTTTTGATTTATTTTAGAAA
TAATTTAAGCATTAAGAGTTATATGCATCATAAATTGACAAGTAATCAGAAGTATACAGA
ATAATAAACGTAATATATTGTAGAATAGCCAAACTTAAAAATGAATATTCATAATTAAAT
AACTTAAATGCTAATAATTTGTTATTGGAACCTTCGCTTTTAGAACTAGCTTTTAAAATT
TATGATTTAAACAGTAATAAACTTGCTTTGTTGGAAGATTTAGACTTATAAACATTCTAA
AATATCAAATATCCCCAATCGCTTATATTTTTGTAAAGCTAAAGGGAGAAAATCATGTTA
ATTTTGAATTCATGGAATTAGAGTGAAGAAAAAAACAATTTATTATAAGAGTATGATAAA
TATGGATAAAAAAAGGCTAGCAGTCACACTGAAAAAGAAGAAAGGAAGCAGAAGAGAGCA
TAATAATTTGAGGAGTAGTTCTGCTTGAAAAAAGAACCATACGGAAATTGCTAAATTCTA
TCACCACTAGGTTTGAAACTTTGCAATTGTGATGAAAAAAAAGTTAAATGGTATCTCAAT
AAAGGACTAGCTACTTTAGTCAGTAGAGAGCCTTACACAATTATAAAATTAAATTTTTAG
CCTAATGGAAAGAATCATGAAGAATTAGAACAAGAAATTCATTTGAATGAAAACCAATTT
TATGCAAGCAAGAGAGAAACTGTTTGTGTAGTCTGTGGAAAAGATGAAAAATTCACTAAA
TATCATGTTATTCCCTCTATATACAGAACTCATTTTCCAAATAAATACAAAAGCCATAGA
TCTCATGACATTTTGTTATTATGTGTGAAATGTCACCAGAAAGCAGGAAAAAACGCAGAT
TTGTTAAAAGATTAACTATTGCAGTAATATAAAATAGAAAAACAGCAGTATTTTAAATAG
CAAAGCTTAAAATATATGGCTTAAAGAATGTATGCTAGTACTAAGTCATACTTAAAAAGC
AAAGAAAAAATGAATAAAGAAAATAGATAAAAGTGTAAAGAAAACATTAGACAATATTTC
GACGAATTGCTCAAAACACCTGATATTTAAAATAAGTTTCCTTAGTTAAAGGACAAACAA
TTTAAAGTCTCAACCACTGGAAAAATTAAAATTGATGAAGAATTTAGGAGTTTCTTTTCT
AATTTAGAAAAAGACTCTAAAAATATTAAAGATGAAGAAAAACAAAATGAGAGAATTTGG
GCTGGATAAAAAGTAGTTGAAAATTTGAAAACAGAAGATGACATTATTTTATTCATAAAA
ATGTGGAGACAGCACTTTTTAGATGTTATGCAACCAAAATATTTACCATTTGGATGGAAT
GTCAATCATAAATTTACAAGAGATTTTGGTAAAGAGTCTGTTTTCAATTAAATTGAAGGT
AATCAAACAGAAGATATCTCCTAACAAAGCCATATAACTGTTTCTGAAGGAATAAATTAG
CAACCATGA

>TTHERM_00630430(protein)
MKNYTIKEFQQYNHSVLNPFQPEKYILIDTLNKLQDLIPILLEQTRLGIDTEQSFAKTYE
GFLCLIQISTDQNDYLIDVLGINSKQGINECLSKVFLCKDIIKIFYAGQQDILWLKRDFD
LSVVNYFDVKECASFLKKSDDNSLIQLIDRYCNYKLDKQKKKELQVSEWSNRPLSKEQLD
YAALDSHYLIKIRYELLCETIQSVGFKRTIEVINQMQQQTLKKYEKKKFDYQYFFDLFQK
QFKHQELYASQIDKQSEVYRIINVIYCRIAKLKNEYSQLNNLNANNLLLEPSLLELAFKI
YDLNSNKLALLEDLDLQTFQNIKYPQSLIFLQSQREKIMLILNSWNQSEEKNNLLQEYDK
YGQKKASSHTEKEERKQKRAQQFEEQFCLKKEPYGNCQILSPLGLKLCNCDEKKVKWYLN
KGLATLVSREPYTIIKLNFQPNGKNHEELEQEIHLNENQFYASKRETVCVVCGKDEKFTK
YHVIPSIYRTHFPNKYKSHRSHDILLLCVKCHQKAGKNADLLKDQLLQQYKIEKQQYFKQ
QSLKYMAQRMYASTKSYLKSKEKMNKENRQKCKENIRQYFDELLKTPDIQNKFPQLKDKQ
FKVSTTGKIKIDEEFRSFFSNLEKDSKNIKDEEKQNERIWAGQKVVENLKTEDDIILFIK
MWRQHFLDVMQPKYLPFGWNVNHKFTRDFGKESVFNQIEGNQTEDISQQSHITVSEGINQ
QP

>TTHERM_00630430(gene)
ATGAAAAATTACACAATTAAAGAGTTTTAACAATATAATCACAGTGTATTAAATCCCTTT
TAGCCTGAAAAGTATATTTTGATAGATACTTTAAATAAGCTGCAGGATTTAATTCCAATA
CTTTTAGAATAAACTAGGTTAGGTAACTTTTCAAATTTATTTATTTTTACATTGTTTATG
TAAATTATTTATAATATACAGGAATAGATACAGAATAGAGCTTTGCCAAGACCTATGAAG
GATTTTTATGCTTGATACAAATTTCAACTGATTAAAATGACTATCTGATAGATGTTTTAG
GCATCAACAGCAAATAAGGAATTAATGAGTGTCTTTCTAAAGTTTTTTTGTGCAAAGACA
TTATTAAAATTTTTTATGCTGGATAATAAGATATTTTATGGCTTAAGAGAGATTTTGATT
TATCAGTAGTAAATTACTTCGATGTAAAAGAATGTGCAAGCTTCCTAAAAAAATCTGATG
ATAATTCACTTATTTAGCTGATTGATCGCTATTGCAATTACAAATTAGATAAGCAAAAGA
AAAAAGAGCTATAAGTAAATAAATCAGTATTTATTTATATATATTTTTATTTTATTTATT
TTCCAAAAGGTTTCAGAGTGGTCAAATAGACCTTTAAGCAAAGAATAGTTAGACTATGCT
GCTTTGGATTCTCATTACTTAATAAAAATTAGATATGAACTGTTGTGTGAGACTATATAA
AGTGTCGGTTTTAAGAGAACTATTGAAGTCATTAACTAAATGCAGTAATAAACTTTAAAG
AAATATGAAAAGAAGAAGTTTGATTATTAGTACTTTTTTGATTTATTTTAGAAATAATTT
AAGCATTAAGAGTTATATGCATCATAAATTGACAAGTAATCAGAAGTATACAGAATAATA
AACGTAATATATTGTAGAATAGCCAAACTTAAAAATGAATATTCATAATTAAATAACTTA
AATGCTAATAATTTGTTATTGGAACCTTCGCTTTTAGAACTAGCTTTTAAAATTTATGAT
TTAAACAGTAATAAACTTGCTTTGTTGGAAGATTTAGACTTATAAACATTCTAAAATATC
AAATATCCCCAATCGCTTATATTTTTGTAAAGCTAAAGGGAGAAAATCATGTTAATTTTG
AATTCATGGAATTAGAGTGAAGAAAAAAACAATTTATTATAAGAGTATGATAAATATGGA
TAAAAAAAGGCTAGCAGTCACACTGAAAAAGAAGAAAGGAAGCAGAAGAGAGCATAATAA
TTTGAGGAGTAGTTCTGCTTGAAAAAAGAACCATACGGAAATTGCTAAATTCTATCACCA
CTAGGTTTGAAACTTTGCAATTGTGATGAAAAAAAAGTTAAATGGTATCTCAATAAAGGA
CTAGCTACTTTAGTCAGTAGAGAGCCTTACACAATTATAAAATTAAATTTTTAGCCTAAT
GGAAAGAATCATGAAGAATTAGAACAAGAAATTCATTTGAATGAAAACCAATTTTATGCA
AGCAAGAGAGAAACTGTTTGTGTAGTCTGTGGAAAAGATGAAAAATTCACTAAATATCAT
GTTATTCCCTCTATATACAGAACTCATTTTCCAAATAAGTAAATTTCATTTCCTTTCTCA
TAAAATATAAAATAGTTCGATGCATTAAAATAAAATTAAATAGATACAAAAGCCATAGAT
CTCATGACATTTTGTTATTATGTGTGAAATGTCACCAGAAAGCAGGAAAAAACGCAGATT
TGTTAAAAGATTAACTATTGCAGTAATATAAAATAGAAAAACAGCAGTATTTTAAATAGC
AAAGCTTAAAATATATGGCTTAAAGAATGTATGCTAGTACTAAGTCATACTTAAAAAGCA
AAGAAAAAATGAATAAAGAAAATAGATAAAAGTGTAAAGAAAACATTAGACAATATTTCG
ACGAATTGCTCAAAACACCTGATATTTAAAATAAGTTTCCTTAGTTAAAGGACAAACAAT
TTAAAGTCTCAACCACTGGAAAAATTAAAATTGATGAAGAATTTAGGAGTTTCTTTTCTA
ATTTAGAAAAAGACTCTAAAAATATTAAAGATGAAGAAAAACAAAATGAGAGAATTTGGG
CTGGATAAAAAGTAGTTGAAAATTTGAAAACAGAAGATGACATTATTTTATTCATAAAAA
TGTGGAGACAGCACTTTTTAGATGTTATGCAACCAAAATATTTACCATTTGGATGGAATG
TCAATCATAAATTTACAAGAGATTTTGGTAAAGAGTCTGTTTTCAATTAAATTGAAGGTA
ATCAAACAGAAGATATCTCCTAACAAAGCCATATAACTGTTTCTGAAGGAATAAATTAGC
AACCATGA