Identifiers and Description

Gene Model Identifier

TTHERM_00649110

Standard Name

RPN12 (26S proteasome regulatory subunit N12)

Aliases

PreTt09225 | 94.m00143 | 3677.m00051

Description

RPN12 26S proteasome non-ATPase regulatory subunit 8

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• proteasome regulatory particle (IEA) | GO:0005838

Molecular Function

• calcium ion binding (IEA) | GO:0005509

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF03399 ) SAC3/GANP family

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12.3%

TetraMine Data

TTHERM_00649110

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17868.1	9.99955252024689e-165	26S proteasome non-ATPase regu latory subunit Nin1/mts3 famil y protein (271 aa)
Oxytricha	Contig2043.0.g70	1.9998323414791308e-36	SAC3/GANP/Nin1/mts3/eIF-3 p25 family
DictyBase	DDB_G0272564	1.000137892321693e-31	psmD8-1 on chromosome: 2 posit ion 2397564 to 2398683
WormBase	WBGene00004468	4.998021988471165e-24	locus:rpn-12 26S proteasome non-ATPase regulatory subunit 8 status:Confirmed UniProt :Q23449 protein_id:CAA93778. 1
Stentor Coeruleus	SteCoe_16339	1.5628821893349888e-18
SGD	YFR052W	0.00000000000003999587784428659	RPN12 Subunit of the 19S regul atory particle of the 26S prot easome lid; synthetically leth al with RPT1, which is an ATPa se component of the 19S regula tory particle; physically inte racts with Nob1p and Rpn3p

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21637855: Xiong J, Yuan D, Fillingham JS, Garg J, Lu X, Chang Y, Liu Y, Fu C, Pearlman RE, Miao W (2011) Gene network landscape of the ciliate Tetrahymena thermophila. PloS one 6(5):e20124

Sequences

>TTHERM_00649110(coding)
ATGACTTTATAGTAAGCTTAACCTCTCTTAGCAGAATTTGAAACTTTAATAGCTTCTAAC
AGCAATGCTCCTAGAGTAGGCTAATTAATATCTTAGTTAAAGCGTATTATATTCCTCCTA
CCCAGTAATGATCCTCTCACTAAAACAAAAAATGAATAAGAGTTGATTGCATCCAGACGT
TTCCACGAATTGTGCATTTTACATAGCATTTAATCCAAAAACATTCAAAGCTTTGAGTCA
GCAATTAATTACTTAAGAGCTTATTACGAAAATTATCCTTAATTGCCAGCTTCTCAAGAT
AGAAATTAAATTATTGCATTGAATTTGTTATATCTTCTTTCTTTCAATAAAAACACTGAA
TACCATTCAGCTTTGGAGTTAGTTCCAGTTGAAGACTTGCACAATAATTAATTTATTCAA
TTCGTTACTGAATTAGAAAAGTAGTTGGCTATTGGTAACTACTCTGAAGCTCTCCTTTCT
AAAAACAAGTCTCCTCTTGCTCACTTCGATATATTCTTGGATAGAATCTTCGAAACTATT
AGATTTGAAACTGCTAGAAGTGCTGAAAAAGCCTATGAAAGTTTATCAATAAATGATGCA
ATTAAATTATTTAACCTTCAAAATGCCGATTAACTTAAAAGCTTTTCAGCTGAACAATCA
AAATAAGGAGAAGAACAAGGATTTTCTTGGGTTTTCGAAAATAATAGATTAGTCTTCCGT
CATAAAGATTCTGATAAAAAAGCATTATTCAACTCTGAATTTCTTATTTCAACAGCACTA
AGTTATGCTCATGAAATTGAAAAGATTGTTTGA

>TTHERM_00649110(protein)
MTLQQAQPLLAEFETLIASNSNAPRVGQLISQLKRIIFLLPSNDPLTKTKNEQELIASRR
FHELCILHSIQSKNIQSFESAINYLRAYYENYPQLPASQDRNQIIALNLLYLLSFNKNTE
YHSALELVPVEDLHNNQFIQFVTELEKQLAIGNYSEALLSKNKSPLAHFDIFLDRIFETI
RFETARSAEKAYESLSINDAIKLFNLQNADQLKSFSAEQSKQGEEQGFSWVFENNRLVFR
HKDSDKKALFNSEFLISTALSYAHEIEKIV

>TTHERM_00649110(gene)
ATGACTTTATAGTAAGCTTAACCTCTCTTAGCAGAATTTGAAACTTTAATAGCTTCTAAC
AGCAATGCTCCTAGAGTAGGCTAATTAATATCTTAGTTAAAGGTATTTCTTTTAAAAGAA
AAAATTAAGTTTAGTATCTATTTTAAGTGAATTTAATCAATCAATAAATCATTTACTTCT
AAATATCAAACATTTACTTTTATAAAAACAAATAGCGTATTATATTCCTCCTACCCAGTA
ATGATCCTCTCACTAAAACAAAAAATGAATAAGAGTTGATTGCATCCAGTAATGAACAGC
TTTAATTTTTAATCTCTAAATTATTTCATAAAACAGATAAAACGATAAATTGGGAGTATT
AAATATTTGTTTTAAAAAAGGACGTTTCCACGAATTGTGCATTTTACATAGCATTTAATC
CAAAAACATTCAAAGCTTTGAGTCAGCAATTAATTACTTAAGAGCTTATTACGAAAATTA
TCCTTAATTGCCAGCTTCTCAAGATAGAAATTAAATTATTGCATTGAATTTGTTATATCT
TCTTTCTTTCAATAAGTAATTCAATATAAATAAATTTTAAAATAGAATTAATAAATTTTA
TTATTAAATAGAAACACTGAATACCATTCAGCTTTGGAGTTAGTTCCAGTTGAAGACTTG
CACAATAATTAATTTATTCAATTCGTTACTGAATTAGAAAAGTAGTTGGCTATTGGTAAC
TACTCTGAAGCTCTCCTTTCTAAAAACAAGTCTCCTCTTGCTCACTTCGATATATTCTTG
GATAGAATCTTCGAAACTATTAGGTAACTTAGGATATTCTTTTGATTTTTAACTGATTAA
GAGATTTATTCTTTATATTTATAAAAAATGAATTTAAATGATTCATTAAATGTGTTAGAG
AGCGTTTGTTAATAGAGTTTATTAAGGGAATTATAACAAATAAATTAGTAGAAACAAATA
AAAGCTAAGAAATTAATATTAATTTTAAAAAAACAGATTTGAAACTGCTAGAAGTGCTGA
AAAAGCCTATGAAAGTTTATCAATAAATGATGCAATTAAATTATTTAACCTTCAAAATGC
CGATTAACTTAAAAGCTTTTCAGCTGAACAATCAAAATAAGGAGAAGTAAATTAACTATT
TGAATGAGCAATTAATTAATCAATAATTATTATTTTTTTTAAGGAACAAGGATTTTCTTG
GGTTTTCGAAAATAATAGATTAGTCTTCCGTCATAAAGATTCTGATAAAAAAGCATTATT
CAACTCTGAATTTCTTATTTCAACAGCACTAAGTTATGCTCATGAAATTGAAAAGATTGT
TTGA