Identifiers and Description

Gene Model Identifier

TTHERM_00471830

Standard Name

RPN10 (26S Proteasome Regulatory subunit N10)

Aliases

PreTt22591 | 56.m00295 | 3686.m00138

Description

Ubiquitin interaction motif family protein; assists in protein degradation

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• proteasome regulatory particle (ISS) | GO:0005838 | Ref:21637855

Domains

• ( PF02809 ) Ubiquitin interaction motif

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.3%

TetraMine Data

TTHERM_00471830

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_11262.1	9.997093137033517e-262	ubiquitin interaction domain-c ontaining protein family prote in (390 aa)
Oxytricha	Contig18962.0.g37	1.9992362000979228e-56	von Willebrand factor type A d omain
SGD	YHR200W	1.9998745702418095e-48	RPN10 Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N -terminus plays a role in main taining the structural integri ty of the RP; binds selectivel y to polyubiquitin chains; hom olog of the mammalian S5a prot ein
DictyBase	DDB_G0275775	2.99915080840225e-45	psmD4 on chromosome: 2 positio n 5689186 to 5690969
Stentor Coeruleus	SteCoe_18678	1.603810890548638e-28
WormBase	WBGene00004466	9.997975313387782e-28	locus:rpn-10 status:Confirme d UniProt:O61742 protein_i d:CCD61298.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:21637855: Xiong J, Yuan D, Fillingham JS, Garg J, Lu X, Chang Y, Liu Y, Fu C, Pearlman RE, Miao W (2011) Gene network landscape of the ciliate Tetrahymena thermophila. PloS one 6(5):e20124
2. Ref:SUPR000174
3. Ref:SUPR000246

Sequences

>TTHERM_00471830(coding)
ATGACTCTAGAAGCTTCAATTGTTATTTTAGATAATACCGAATATGCAAGAAATGGGGAC
CATTTGCCTTCCAGATATGAAGCATAAGCAGAAACAATCCAGGCTATAATAAATGCAAAA
TAATAAATGAATATGGAAAATGCAGTTGGTATATTAACTATGGGAGGCCCATAAGTTGAA
GTATTAATCACACCTAGCGCAGATCCTGATGCTATTTTAGGCTGCTTATTTGGCGTAAAG
CTTAGAGGTGAAAAAGCTCACTTTTTAAATGCTCTTTAAATTGCTTAGCTTGGATTAAAA
CACAGAAAAAATAAAAATATGAGATAAAGGATAATCGTTTTTGTTGCATCACCAATTGTT
GAAGATGAAAAAACTTTGGAAAGAGTTGCAAAGTAATTAAAAAAGAATAATGTTAGTGTT
GATATTGTTAATCTATGTTAAAGTGGAGTTAATTAAATTGAAAAACTAGACAAATTCATT
CAAACTGTTAATTCAGGTGATTCTTCATACTTTTTAAATGTTTAAAGCGGCATTACTAGT
TTAACAGAAACCCTCTTTAACTCTCCTATATTAAACCGTTTCCTTAGTGGTTCTAACGCT
AACTAAGCCTCGAGTGTAGGTAATGTACCAATCAATCCAACCTAAGCTGGTGGAGCTAAT
CCATTTGCTGAATATGGTGGAATTGATCCCTCTGAAGACCCCGAATTAGCTTAAGCTATG
AAGCTTTCTCTAGAAGAAGAAAAGAGAATTTAAGAATAATTAGAGAGAGAAAAGAATTAA
TAATAATAATAATAGCAAGCACCTAGTTAACCAGCATAAGAAAATGCAACTAGCTTGGCT
TAATAGAATTTAAATACTTCTGCAAATAATCCATCATTTGTAAATGAAACAATGTAAGAT
GAAAATTAGGGCCTTTTAGCAAACAAAGATGATTTTGATGAATTGACAGAAGAAGAGTTG
ATGAATCAAGCTATATTAGCTTCATAATAAGAAAACCCATTTGAAGCATAGCAAGGAGCA
GAAAACAAAGAACCTAGAAAAGAATAAACCAAAAAAGAAGATGATGAATCTGTATAAGCT
AATTTAATGTAGGATGAAAAGTTTGTTGAAGATTTGTTAAATTTAGTTGGTAAAGGAGAT
GAGAAAAAAGATGATAAAAAAGAAAATGAAAAGAAGTGA

>TTHERM_00471830(protein)
MTLEASIVILDNTEYARNGDHLPSRYEAQAETIQAIINAKQQMNMENAVGILTMGGPQVE
VLITPSADPDAILGCLFGVKLRGEKAHFLNALQIAQLGLKHRKNKNMRQRIIVFVASPIV
EDEKTLERVAKQLKKNNVSVDIVNLCQSGVNQIEKLDKFIQTVNSGDSSYFLNVQSGITS
LTETLFNSPILNRFLSGSNANQASSVGNVPINPTQAGGANPFAEYGGIDPSEDPELAQAM
KLSLEEEKRIQEQLEREKNQQQQQQQAPSQPAQENATSLAQQNLNTSANNPSFVNETMQD
ENQGLLANKDDFDELTEEELMNQAILASQQENPFEAQQGAENKEPRKEQTKKEDDESVQA
NLMQDEKFVEDLLNLVGKGDEKKDDKKENEKK

>TTHERM_00471830(gene)
ATGACTCTAGAAGCTTCAATTGTTATTTTAGATAATACCGAATATGCAAGAAATGGGGAC
CATTTGCCTTCCAGATATGAAGCATAAGCAGAAACAATCCAGGCTATAATAAATGCAAAA
TAATAAATGAATATGGAAAATGCAGTTGGTATATTAACTATGGGAGGCCCATAAGTTGAA
GTATTAATCACACCTAGCGCAGATCCTGATGCTATTTTAGGCTGCTTATTTGGCGTAAAG
CTTAGAGGTGAAAAAGCTCACTTTTTAAATGCTCTTTAAATTGCTTAGCTTGGATTAAAA
CACAGAAAAAATAAAAATATGAGATAAAGGATAATCGTTTTTGTTGCATCACCAGTAATT
AATTTATTATTTAAACTAATTTTTCAAACTTATAAAAGCATTAAAACTTTAAATTAAATA
TGAAAACTACATAAAATATTTTAGTAGGAATTTTATTTTTGTTGAAAGAAAGAAAGATTT
GAATTTTTAATTTTTAATAAATTTTATAATTTTTGTTAAATAAATGATTATTTATAAATA
TAAAATTAGATTGTTGAAGATGAAAAAACTTTGGAAAGAGTTGCAAAGTAATTAAAAAAG
AATAATGTTAGTGTTGATATTGTTAATCTATGTTAAAGTGGAGTTAATTAAATTGAAAAA
CTAGACAAATTCATTCAAACTGTTAATTCAGGTGATTCTTCATACTTTTTAAATGTTTAA
AGCGGCATTACTAGTTTAACAGAAACCCTCTTTAACTCTCCTATATTAAACCGTTTCCTT
AGTGGTTCTAACGCTAACTAAGCCTCGAGTGTAGGTAATGTACCAATCAATCCAACCTAA
GCTGGTGGAGCTAATCCATTTGCTGAATATGGTGGAATTGATCCCTCTGAAGACCCCGAA
TTAGCTTAAGCTATGAAGCTTTCTCTAGAAGAAGAAAAGAGAATTTAAGAATAATTAGAG
AGAGAAAAGAATTAATAATAATAATAATAGCAAGCACCTAGTTAACCAGCATAAGAAAAT
GCAACTAGCTTGGCTTAATAGAATTTAAATACTTCTGCAAATAATCCATCATTTGTAAAT
GAAACAATGTAAGATGAAAATTAGGGCCTTTTAGCAAACAAAGATGATTTTGATGAATTG
ACAGAAGAAGAGTTGATGAATCAAGCTATATTAGCTTCATAATAAGAAAACCCATTTGAA
GCATAGCAAGGAGCAGAAAACAAAGAACCTAGAAAAGAATAAACCAAAAAAGAAGATGAT
GAATCTGTATAAGCTAATTTAATGTAGGATGAAAAGTTTGTTGAAGATTTGTTAAATTTA
GTTGGTAAAGGAGATGAGAAAAAAGATGATAAAAAAGAAAATGAAAAGAAGTGA