Identifiers and Description

Gene Model Identifier

TTHERM_00094210

Standard Name

RPC5 (RNA polymerases I and III subunit 5)

Aliases

PreTt16576 | 6.m00650 | 3836.m02233

Description

RPC5 DNA-directed RNA polymerase I and III subunit RPAC1; Fifth largest subunit of RNA polymerases I and III; homolog of RPC40 in yeasts and RPA40 in humans; expressed in macronucleus of vegetative cells and weakly in early stages of conjugation

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• DNA-directed 5'-3' RNA polymerase activity (IEA) | GO:0003899
• protein dimerization activity (IEA) | GO:0046983

Biological Process

• transcription (IEA) | GO:0006350

Domains

• ( PF01193 ) RNA polymerase Rpb3/Rpb11 dimerisation domain
• ( PF01000 ) DNA-directed RNA polymerase, alpha subunit,

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.2%

TetraMine Data

TTHERM_00094210

WebApollo

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Tetrahymena Stock Center

• ( SD02176 ) Macronucleus: HA tagged RPC5
• ( SD02718 ) Macronucleus: HA tagged RPC5

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02582.1	9.997093137033517e-262	DNA-directed RNA polymerase I polypeptide (340 aa)
Oxytricha	Contig22041.0.g30	9.995094197784295e-101	RNA polymerase Rpb3/RpoA inser t domain
DictyBase	DDB_G0282339	8.003693242657371e-87	rpa5 on chromosome: 3 position 5656917 to 5658092
WormBase	WBGene00019275	2.0004485223439647e-69	locus:rpac-40 status:Confirm ed UniProt:Q9UAY9 protein_ id:CCD68663.1
SGD	YPR110C	3.0000115468388957e-66	RPC40 RNA polymerase subunit A C40, common to RNA polymerase I and III
Stentor Coeruleus	SteCoe_7522	3.0144087850653746e-40

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15470252: Mochizuki K, Gorovsky MA (2004) RNA polymerase II localizes in Tetrahymena thermophila meiotic micronuclei when micronuclear transcription associated with genome rearrangement occurs. Eukaryotic cell 3(5):1233-40

Sequences

>TTHERM_00094210(coding)
ATGTCAAATAAAACTTAAAAAATGAAGAAAAATATTGTCTTCACCAACGAAGGCATTCAA
CACAGCTAGGAAATGAACTATAGCGCTGCTTTTACTAGTGAAGAAGATTTCAATACATTC
AAGGAAAACATTAAAATAGAAGTTATTAGATATGATAATAAAAATAAAGAATTAGAATTT
GATTTAATGGGTGTCGATGCTCCTATTGCTAACGCTTTGAGAAGAATTATGATTGCAGAA
GTTCCTACAATGGCTATCCACAAGGTTTATATTTACTAAAATACTTCTATTATTCCTGAT
GAAGTTTTGGCTCACAGACTTGGTTTAATTCCTATTTATGCTGACCCTCGTCTTTTCGAA
GAAAAGCAAGAAGAAGACGAGTATAATGAAAAAAATTCTTTAAAGTTTACATTAAAGATT
AAATGCTCTAAGAAAGAATAGTACAAAAATTACTCTGAAGCTGATTTAGAAAATTTAACA
CCTGAAACCTACTTAGAAAATGCTATTGTCTATAGCGGTGATTTCAAATGGGTTTCTTAA
GGAGAATAAAATAAAAAATTTGAAGAGAATCCAATCAGAATGGTCCATGATAATATTATT
GTAGCTAAGTTAAGAGAAAACCAAGAAATTATTTGTGAAGTTATTTGTTAAAAGGGTATT
GGAAAAACACATGCCAAATGGTCTCCTGTTTGTACTGCTTACTATCGTTTAATGCCTGAA
ATAAACATAAATAGTGATATCACCGGAGCTAAAGCTCAAGAATTGAAAGAACGTTGCCCT
CTTAAAGTTTATGATGTTTAAAATAATAAGGCTATTGTTTCTAACGAAAGAGCTTGCACT
ATGTGCAGAGAATGCATAAGAGAAGATGAAGAATTCAATTCAAAGATTGAATTGGCCAAA
AAGAAAGAGCATTTTATTTTTACTGTAGAAAGCGTTGGAATCTACGAACCTCACGAGATA
GTAAAGGAAGCAATCTAGATATTAAAATAAAAAGCATCTAGTTTTATGCTAAACCTATGA

>TTHERM_00094210(protein)
MSNKTQKMKKNIVFTNEGIQHSQEMNYSAAFTSEEDFNTFKENIKIEVIRYDNKNKELEF
DLMGVDAPIANALRRIMIAEVPTMAIHKVYIYQNTSIIPDEVLAHRLGLIPIYADPRLFE
EKQEEDEYNEKNSLKFTLKIKCSKKEQYKNYSEADLENLTPETYLENAIVYSGDFKWVSQ
GEQNKKFEENPIRMVHDNIIVAKLRENQEIICEVICQKGIGKTHAKWSPVCTAYYRLMPE
ININSDITGAKAQELKERCPLKVYDVQNNKAIVSNERACTMCRECIREDEEFNSKIELAK
KKEHFIFTVESVGIYEPHEIVKEAIQILKQKASSFMLNL

>TTHERM_00094210(gene)
ATGTCAAATAAAACTTAAAAAATGAAGAAAAATATTGTCTTCACCAACGAAGGCATTCAA
CACGTATAGATTAAAAATCATTTTTTTATTTTAAATAAAAGTGTTCAAAGAACTAAGCAA
TTTTAGCCAATTTCATCATATTTACTAAATTAGAATCTTTAATGAAGTATTTAATCAGGA
AATCTAAAAAATGATTTCTAAATTTGATGAATTAGAAAATGAATTAACAAATTTAATCAA
ATAAAAATTCTATATCAAATTTAAATGAGCTTAAACATATTTTATCTTATCAAAAGAGCT
AGGAAATGAACTATAGCGCTGCTTTTACTAGTGAAGAAGATTTCAATACATTCAAGGAAA
ACATTAAAATAGAAGTTATTAGATATGATAATAAAAATAAAGAATTAGAATTTGATTTAA
TGGGTGTCGATGCTCCTATTGCTAACGCTTTGAGAAGAATTATGATTGCAGAAGTATATT
ATTTTTCTTTTTTTCAAATTTTTAGTTTTCTTGAGCGAAAATTATCATTAGTTTCTAAAA
TACTATTAAAAATTAATAGGTTCCTACAATGGCTATCCACAAGGTTTATATTTACTAAAA
TACTTCTATTATTCCTGATGAAGTTTTGGCTCACAGACTTGGTTTAATTCCTATTTATGC
TGACCCTCGTCTTTTCGAAGAAAAGCAAGGTAAATTCATTTTATAAAATTAAAGAAGAAG
ATTTATTTATAAACAAGATTTTATAGCAATAAAAAAGTAAAGTGGATAGATAGCTAAATT
AATTAATTCTTAATTTTTATATAAATTATTTTATTTACTGCTTTTGAATTTAATAATAAT
CAAATTTTAAATAATAAATTTAGAAGAAGACGAGTATAATGAAAAAAATTCTTTAAAGTT
TACATTAAAGATTAAATGCTCTAAGAAAGAATAGTACAAAAATTACTCTGAAGCTGATTT
AGAAAATTTAACACCTGAAACCTACTTAGAAAATGCTATTGTAAGATAAATTTTTTGATT
TAGGAAGCGAATTTTTAAATGATCTAATACATTTTAATTAGGTCTATAGCGGTGATTTCA
AATGGGTTTCTTAAGGAGAATAAAATAAAAAATTTGAAGAGAATCCAATCAGAATGGTCC
ATGATAATATTATTGTAGCTAAGTTAAGAGAAAACCAAGAAATTATTTGTGAAGTTATTT
GTTAAAAGGGTATTGGAAAAACACATGCCAAATGGTCTCCTGTTTGTACTGCTTACTATC
GTTTAATGCCTGAAATAAACATAAATAGTGATATCACCGGAGCTAAAGCTCAAGAATTGA
AAGAACGTTGCCCTCTTAAAGTTTATGATGTTTAAAGTAATTTAAAATAATTAATATTAA
ATTAACATCAGCTAATATAAATAAAACTATCTATTTTAATAGATATTTAATATTTTTTAT
TATTCTGTAAACAAATACCAAACAAGTATCAAGTCAATTTCTGATAACTAAAAATTGATT
TCTTGCTAAATTATAATTATCAAAAAATTACTTGTTTGTTAGATATAAATAAAAAGACAC
AGCTAATACAAATCAAATATTAATTATATTCTAAAATTTATTGGTCTAAAATTATGATCT
AAAAAAAATATCTAAGACTTTATATAGCTTAAAAAATTTTTTGTTTACTTAAATTAAATT
AATTTTTATAAATAGATAATAAGGCTATTGTTTCTAACGAAAGAGCTTGCACTATGTGCA
GAGAATGCATAAGAGAAGATGAAGAATTCAATTCAAAGATTGAATTGGCCAAAAAGAAAG
AGCATTTTATTTGTAAAATATTCATTATATTTAGATTAAATTGATAGGAATTTATATAAG
AAATAATAATTTTACTGATCGGAAAGGGAAGATATAGAAAAATTAATTAATTTGGATTTA
AGCTAATTTAATATATTTATTAGTTAAAATTACAATAATTACCTTATATTAATTTATATT
TTTAATATGCAAATAGTTACTGTAGAAAGCGTTGGAATCTACGAACCTCACGAGATAGTA
AAGGAAGCAATCTAGATATTAAAATAAAAAGCATCTAGTTTTATGCTAAACCTATGA