Identifiers and Description

Gene Model Identifier

TTHERM_00780750

Standard Name

RFC4 (Replication factor C subunit 4)

Aliases

PreTt01287 | 130.m00097 | 3738.m00033

Description

Subunit of Replication factor C (RF-C), which acts as a clamp loader of the proliferating cell nuclear antigen (PCNA)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663

Molecular Function

• DNA clamp loader activity (IEA) | GO:0003689
• ATP binding (IEA) | GO:0005524

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF04548 ) AIG1 family
• ( PF00004 ) ATPase, AAA family
• ( PF08542 ) Replication factor C
• ( TIGR02881 ) stage V sporulation protein K
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF06144 ) DNA polymerase III, delta subunit
• ( PF08718 ) Glycolipid transfer protein (GLTP)
• ( TIGR00678 ) DNA polymerase III, delta' subunit
• ( TIGR02397 ) DNA polymerase III, subunit gamma
• ( TIGR02928 ) orc1/cdc6 family replication initiation protein
• ( PF07726 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00780750

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_18674.1	9.997093137033517e-262	ATPase, AAA family protein (32 4 aa)
Oxytricha	Contig3514.0.g13	6.996820840887259e-117	Replication factor C C-termina l domain
WormBase	WBGene00004338	5.001313616964319e-114	locus:rfc-2 status:Confirmed UniProt:O44175 protein_id :CCD63484.1
DictyBase	DDB_G0291868	1.9999366565375063e-113	rfc2 on chromosome: 6 position 850606 to 851622
SGD	YOL094C	1.9994050701445255e-104	RFC4 Subunit of heteropentamer ic Replication factor C (RF-C) , which is a DNA binding prote in and ATPase that acts as a c lamp loader of the proliferati ng cell nuclear antigen (PCNA) processivity factor for DNA p olymerases delta and epsilon
Stentor Coeruleus	SteCoe_4442	6.991989996645917e-56

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00780750(coding)
ATGGCAAGTAAAGAAATATGGCTTGAGAAGTATCGTCCTCGTACATTAGATGAAGTTTAA
GGTAATGAAGATGCCTTGATCAAGTTAAGAACAATTGCAGAGGAAGGTAACGTCCCAAAT
ATGATATTAGTTGGTCCTCCTGGTATTGGTAAAACTAGTTCAGTACTTTGTTTAGCAAGA
ACACTACTTGCAGATGTATTTGATTCCTGTGCTCTTGAAATGAATGCTTCTGACGAAAGA
GGTATTGATGTTGTCAGAGAAAAAATAAAGAGTTTTGCATAAAAAAAGGTAAATTTAAAG
CCTGGTCTTCATAAAATAATTATTCTTGATGAAGCTGATTCATTAACTGAAGGAGCTTAA
CAGGCTTTAAGAATGATTATTAGTGATTTTGCTGATACTACTAGATTTGTATTAAGTTGT
AATGATAGTTCAAAATTAATTGATGCTATTCAAAGTAGATGTGCTATTTTAAGATTTACT
AAGTTAACTGACGAATAAATATTAAGAAGACTTGAAGAAATTGTAGAAAAAGAAAATATC
AAAATAGATAAGGGAGGTAAAGAAGCTCTACTCTTTACATGTGAAGGAGATATGAGATAA
GCAATTAACAATTTATAAGCTACCTACACTGCTTTCAAACTTGTAAATAAAGAAAATGTC
CTTAAGGTTTGTGATGTCCCAAATGTTGAAGTCCTTTAACAAGTTATTGCAGAATGTGTT
AATGGAAACTTCCATGCTGCTTAAAAGAAACTTTATCCACTATGGGAAGAAGGATATACT
GCTTACGATTTAGTTAACAATTTATATAAACTTATCCAAACTCAAGATATGGATAAATAG
CTTCAATATGAATTTATGAGAGAAATGGCTTTCCTTAAGATGAAAGTTCTTGAAGGCTTG
CCAACATTCTTGCAGATTTCTGGATATCTTGCTAAAATATCTTCTATTGCAAACTCCAAA
AAATGA

>TTHERM_00780750(protein)
MASKEIWLEKYRPRTLDEVQGNEDALIKLRTIAEEGNVPNMILVGPPGIGKTSSVLCLAR
TLLADVFDSCALEMNASDERGIDVVREKIKSFAQKKVNLKPGLHKIIILDEADSLTEGAQ
QALRMIISDFADTTRFVLSCNDSSKLIDAIQSRCAILRFTKLTDEQILRRLEEIVEKENI
KIDKGGKEALLFTCEGDMRQAINNLQATYTAFKLVNKENVLKVCDVPNVEVLQQVIAECV
NGNFHAAQKKLYPLWEEGYTAYDLVNNLYKLIQTQDMDKQLQYEFMREMAFLKMKVLEGL
PTFLQISGYLAKISSIANSKK

>TTHERM_00780750(gene)
ATGGCAAGTAAAGAAATATGGCTTGAGAAGTACTTTTTTAGCATTAATTAGAATTAGCAT
TGAAAATTAATAATTAATTGCTATATTTTAACTGCCATTAAATAAATAATATAATATACT
TATTAGGTATCGTCCTCGTACATTAGATGAAGTTTAAGGTAATGAAGATGCCTTGATCAA
GTTAAGAACAATTGCAGAGGAAGGTAACGTCCCAAATATGATATTAGTTGGTCCTCCTGG
TATTGGTAAAACTAGTTCAGTACTTTGTTTAGCAAGAACACTACTTGCAGATGTATTTGA
TTCCTGTGCTCTTGAAATGAATGCTTCTGACGAAAGAGGTATTGATGTTGTCAGAGAAAA
AATAAAGAGTTTTGCATAAAAAAAGGTAAATTTAAAGCCTGGTCTTCATAAAATAATTAT
TCTTGATGAAGCTGATTCATTAACTGAAGGAGCTTAACAGGTAATTAGGATTATTTTCAT
TTTTTTATTTTCCCTCTCTTTTTTGTTTTTTAAACAAGTGCGCCAAAAGGAAAATGGCTC
TGAGCATTAGAATATTTGATTAATATAAACAAATTAAGAGATAGTTTAATTTTTTTCTTT
ATAATTTATAGGCTTTAAGAATGATTATTAGTGATTTTGCTGATACTACTAGATTTGTAT
TAAGTTGTAATGATAGTTCAAAATTAATTGATGCTATTCAAAGTAGATGTGCTATTTTAA
GATTTACTAAGTTAACTGACGAATAAATATTAAGAAGACTTGAAGAAATTGTAGAAAAAG
AAAATATCAAAATAGATAAGGGAGGTAAAGAAGCTCTACTCTTTACATGTGAAGGAGATA
TGAGATAAGCAATTAACAATTTATAAGCTACCTACACTGCTTTCAAACTTGTAAATAAAG
AAAATGTCCTTAAGGTTTGTGATGTCCCAAATGTTGAAGTCCTTTAACAAGTTATTGCAG
AATGTGTTAATGGAAACTTCCATGCTGCTTAAAAGAAACTTTATCCACTATGGGAAGAAG
GATATACTGCTTACGATTTAGTTAACAATTTATATAAACTTATCCAAACTCAAGATATGG
ATAAATAGCTTCAATATGAATTTATGAGAGAAATGGCTTTCCTTAAGATGAAAGTTCTTG
AAGGCTTGCCAACATTCTTGCAGATTTCTGGATATCTTGCTAAAATATCTTCTATTGCAA
ACTCCAAAAAATGA