Identifiers and Description

Gene Model Identifier

TTHERM_00245150

Standard Name

RFC2 (Replication factor C sububit 2)

Aliases

PreTt02411 | 21.m00242

Description

Subunit of Replication factor C (RF-C), which acts as a clamp loader of the proliferating cell nuclear antigen (PCNA)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA clamp loader activity (IEA) | GO:0003689

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00931 ) NB-ARC domain
• ( PF06068 ) TIP49 C-terminus
• ( PF00004 ) ATPase, AAA family
• ( PF08542 ) Replication factor C
• ( PF00270 ) DEAD/DEAH box helicase
• ( TIGR02902 ) ATP-dependent protease LonB
• ( PF06144 ) DNA polymerase III, delta subunit
• ( TIGR00678 ) DNA polymerase III, delta' subunit
• ( PF04851 ) type III restriction enzyme, res
• ( TIGR02237 ) DNA repair and recombination protein
• ( TIGR02397 ) DNA polymerase III, subunit gamma
• ( TIGR02928 ) orc1/cdc6 family replication initiation protein
• ( PF07726 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.9%

TetraMine Data

TTHERM_00245150

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_00630.1	9.997093137033517e-262	ATPase, AAA family protein (37 1 aa)
Oxytricha	Contig22064.0.g10	3.998986577109865e-118	ATPase family associated with various cellular activities (A AA)
DictyBase	DDB_G0286027	2.999467474389571e-105	rfc4 on chromosome: 4 position 3966261 to 3967572
SGD	YJR068W	2.999180586171967e-98	RFC2 Subunit of heteropentamer ic Replication factor C (RF-C) , which is a DNA binding prote in and ATPase that acts as a c lamp loader of the proliferati ng cell nuclear antigen (PCNA) processivity factor for DNA p olymerases delta and epsilon
WormBase	WBGene00004340	9.995417076252815e-72	locus:rfc-4 Replication fact or C subunit 4 status:Confir med UniProt:P53016 protein _id:CCD63405.1
Stentor Coeruleus	SteCoe_4894	4.1863939993042314e-51

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00245150(coding)
ATGTAGGGCAAATTACTATTTAAAGGTTAGGCCGCTCCTAAGGGTGCTGCTGCAGGAGCA
AATACAAAGGATAACAATAGAATGGAAGAAGAAACTAAAACAGAAGAACTTAATAATAAT
TTGCTTCCTTGGGTTGAAAAATATCGTCCTAATAAAATTGAAGAAGTCAGCTACTAAGAG
GAAGTAATAAAGTCTCTCTAAGGTGTTTTATTATCAGGAAATCTACCTCACTTGATTCTA
CATGGACCTCCTGGTACTGGTAAAACTTCAAGTATCCTTGCCTTTGCAAAGCAACTTTAC
GGACCAACTTTTTACAAAGAGAGAATCTTAGAATTAAATGCATCTGATGATAGAGGTATT
CAAATAGTCAGAGATAAAATAAAAAAATTTGCACAATAAGTTGTCTCTAAGAATCCAGAT
AAATCATTTAAATGCCCAAATTTCAAAATTATTATTTTGGACGAAGCAGACTCAATGACT
ACAGAAGCTCAGTCAGCTTTAAGAAGAATCATTGAAGACACCTCTTCAACCACTCGTTTT
TGTATTATCTGTAACTACATTACTAAGATTATAGAACCATTAGGTAGTAGATGTGTCAAA
TTCAGATTTAAACCTATTCCACTTGAAGCTTAAATAACTAAACTAGAAGAAATATGTAAA
ACAGAAGATATTGAATATGAAAAGGAAGCTCTTGAAAAATTAATTAAAATATCAAACGGT
GATTTGAGAAAAAGTGTAAATCTTCTATAATCTGCATCTACTTTGTATGAAAAGGATATT
AAAGTTGAAGTTATTGAAGAAATTTCAGGAAGTATTCCTGACAATTAAGTATAGAAATTA
TATAAACTTCTTATTGGCAAGGATTTTGATAAATTAAAAGAAGGAGTTAAATAGTTCTTA
TACTAAGGGTATTCTCCTGATTAATTACTTTACTAATTCTCAGAGTATATCATTAGTTCT
AAAGATTTCAATGAAGTTAAAAAAGCTAGAATCCTTGAAAAAATTGCATTAGCTGATAAA
GGTTTAAACGAAAGAGCAGACTCTGAGTTGCAAATATTAAACATGTTCTCAAGCTGTCTT
TCTGTTTTACAAAATCCTGATACTGATTTAAAGAAAAAGTGA

>TTHERM_00245150(protein)
MQGKLLFKGQAAPKGAAAGANTKDNNRMEEETKTEELNNNLLPWVEKYRPNKIEEVSYQE
EVIKSLQGVLLSGNLPHLILHGPPGTGKTSSILAFAKQLYGPTFYKERILELNASDDRGI
QIVRDKIKKFAQQVVSKNPDKSFKCPNFKIIILDEADSMTTEAQSALRRIIEDTSSTTRF
CIICNYITKIIEPLGSRCVKFRFKPIPLEAQITKLEEICKTEDIEYEKEALEKLIKISNG
DLRKSVNLLQSASTLYEKDIKVEVIEEISGSIPDNQVQKLYKLLIGKDFDKLKEGVKQFL
YQGYSPDQLLYQFSEYIISSKDFNEVKKARILEKIALADKGLNERADSELQILNMFSSCL
SVLQNPDTDLKKK

>TTHERM_00245150(gene)
ATGTAGGGCAAATTACTATTTAAAGGTTAGGCCGCTCCTAAGGGTGCTGCTGCAGGAGCA
AATACAAAGGATAACAATAGAATGGAAGAAGAAACTAAAACAGAAGAACTTAATAATAAT
TTGCTTCCTTGGGTTGAAAAATAGTAATTAATCAATTATTTTAATTTAGCTTATTTATAA
ATCAAAGATGATTTAACTTAATAAAATAGTCGTCCTAATAAAATTGAAGAAGTCAGCTAC
TAAGAGGAAGTAATAAAGTCTCTCTAAGGTGTTTTATTATCAGGAAATGTAATTTCATAT
TAGTAGCCAGTTTAGTTATTAGAATAAAATTATTTTTTGCTCAAATAAAAAGCTACCTCA
CTTGATTCTACATGGACCTCCTGGTACTGGTAAAACTTCAAGTATCCTTGCCTTTGCAAA
GCAACTTTACGGGTAAATAAATAAATAATCAACATAAAGATGTTAAAAATATTTGCAATC
CAAACACATAGGCTTATAAATAAATATGATTTTATTTTTAATCAATAGACCAACTTTTTA
CAAAGAGAGAATCTTAGAATTAAATGCATCTGATGATAGAGGTATTCAAATAGTCAGAGA
TAAAATAAAAAAATTTGCACAATAAGTTGTCTCTAAGAATCCAGATAAGTAAAATAAAAC
TGATAGCATTAGGTGTAGATTAAATATTTATAATATTTTGGATAAAATAGATCATTTAAA
TGCCCAAATTTCAAAATTATTATTTTGGACGAAGCAGACTCAATGACTACAGAAGCTCAG
TCAGCTTTAAGAAGAATCATTGAAGACACCTCTTCAACCACTCGTTTTTGTATTATCTGT
AACTACATTACTAAGTAAAATAAATTTATTTCAGTTTTTACTAAGCTATTATAAAGATAT
AAAAATTAACTACAGGTTAGCCATATTATTTTACTAATTTGTTATAAAGATATAAAAATT
TACTGCAGAATAGCCATATTATTAAATAGAATATTAAATATTTCAATAAAAATTAATGTA
AATAGGCTAAATATTATTAGGCAATTTAAAATTTTAATCTAAAAATAAGAATTTAAAATA
GAATAAATTATATTAATTAAAAATGAAAAAACTTGTATAAAATAACAATATTTTAAATAA
AAATAACATAATACAATTATGCAGCTATATTTAATATTTTTAACATATTAAATTTTTAAT
AATAAAAGGATTATAGAACCATTAGGTAGTAGATGTGTCAAATTCAGATTTAAACCTATT
CCACTTGAAGCTTAAATAACTAAACTAGAAGAAATATGTAAAACAGAAGATATTGAATAT
GAAAAGGAAGCTCTTGAAAAATTAATTAAAATATCAAACGGTGATTTGAGAAAAAGTGTA
AATCTTCTATAATCTGCATCTACTTTGTATGAAAAGGATATTAAAGTTGAAGTTATTGAA
GAAATTTCAGGAGTAAATTATTTACTTTGTATAAACGTATTAAATTATTTTTAAATAAAA
ATAAAGAGTATTCCTGACAATTAAGTATAGAAATTATATAAACTTCTTATTGGCAAGGAT
TTTGATAAATTAAAAGAAGGAGTTAAATAGTTCTTATACTAAGGGTATTCTCCTGATTAA
TTACTTTACTAATTCTCAGAGTATATCATTAGTTCTAAAGATTTCAATGAAGTTAAAAAA
GCTAGAATCCTTGAAAAAATTGCATTAGCTGATAAAGGTTTAAACGAAAGAGCAGACTCT
GAGTTGCAAATATTAAACATGTTCTCAAGCTGTCTTTCTGTTTTACAAAATCCTGATACT
GATTTAAAGAAAAAGTGA