Identifiers and Description

Gene Model Identifier

TTHERM_00939110

Standard Name

RFC1 (Homolog of Replication factor C subunit 1)

Aliases

PreTt03760 | 170.m00089

Description

BRCA1 C Terminus (BRCT) domain AAA+ ATpase with a BRCT domain at the N-terminus (Cryptosporidium parvum)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663
• intracellular (IEA) | GO:0005622

Molecular Function

• DNA clamp loader activity (IEA) | GO:0003689
• ATP binding (IEA) | GO:0005524

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF03047 ) COMC family
• ( PF00004 ) ATPase, AAA family
• ( PF08243 ) SPT2 chromatin protein
• ( PF04702 ) Vicilin N terminal region
• ( PF00533 ) BRCA1 C Terminus (BRCT) domain
• ( PF03215 ) Rad17 cell cycle checkpoint protein
• ( PF08519 ) Replication factor RFC1 C terminal
• ( TIGR02397 ) DNA polymerase III, subunit gamma

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.7%

TetraMine Data

TTHERM_00939110

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_19334.1	9.997093137033517e-262	BRCT domain-containing protein (1154 aa)
Oxytricha	Contig2682.0.g45	1.9999788875029746e-125	Replication factor RFC1 C term inal domain
WormBase	WBGene00004337	1.999618694399617e-70	locus:rfc-1 status:Confirmed UniProt:Q18841 protein_id :CAA99812.1
SGD	YOR217W	7.000846320060671e-65	RFC1 Subunit of heteropentamer ic Replication factor C (RF-C) , which is a DNA binding prote in and ATPase that acts as a c lamp loader of the proliferati ng cell nuclear antigen (PCNA) processivity factor for DNA p olymerases delta and epsilon
DictyBase	DDB_G0285961	2.998990600740728e-62	rfc1 on chromosome: 4 position 3845828 to 3850119
Stentor Coeruleus	SteCoe_1680	7.667648073722e-53

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00939110(coding)
ATGAAAAAGAATAACTAGTCAAATAGTTTATTGAAATATTTTAGTAAATAAGATACCAAA
ACTGTTAATAATTCGTAAAATTCTTCTAAAGACAAAGACAAAGAAAAAGATTCTAAAGAA
AAAACAAAAGAATCTTCATCTAAAACTTAATACAAATAAACTAAGGAAATAAAGCATGAA
GAACCTAAAAAATAAGAACAAAATAAGAAGCAAAATGAATAAAAGGAAGAAAAAGAAAAA
AGAAATTTTAGTTAAGATATAAAAAATACTCGATCAACTCCCATTAAAAAAGTTTAAGAG
TAGAAAAAAGAAGAAATAAAATCTTCTAAAAATAAAATGAATGTAGAGAATTCAGGAACT
GAAGAATTATCTGCCACTGAAAGTCTAACAGAACCTGCATTAAGCGAAAATGAGGAAAAA
AATAAATCTTCCAATCAAAATAAAGGGAGAAATGTTTCAAGTGATAATAAATAGTAATAA
GCGAAAGACGTAAAAATGAATTAAAGTTAGACAAGATCAAATGATAATAAAAAAGTAGAT
CCCAAGTAATCAAGTAAAAAGCCATAAAAGAAAAATGAGACTGATGACGATGATTACGGT
ATTAATGATGAAGAAGAGGACTTACCCAAAAATAGCAAACAAAAAAAATTAGTATAAGGG
AGCCAAAAAAAAAATAAAATGATAGTTGAAGATGATGATTATGAAGAAAAAGAAGAGGAT
AAAGATGATAAGGAGTTGCATAAGAATAGTAAATCAAAAAGGGTTTTAGTAAAAGGAGGA
TAAAAATAAAATAAAATGATAGATGAAGATGACTATGATGCTGAAGAAGTAGATGATTAT
GTAGAAGTAAAAAAAACTACCAGCAGGACAAAGGCTTTAGAAGAAAAGAATTTAAAAAAA
ATAGAAGAAAATAAACAAAAGTAATAAGTTTCTGCAAAAAAGGATAAAGCTCCTCCTTAA
AAAGATAAAAATAGTTCTAATGGAAATATAGATTCTGATATTTTAGCAGGATAAACAATT
GTTTTTACTGGTGATTTTGATGGAATTTCTAGAGATACTATGTCTAAAATAGTTACAGAT
ATGGGAGCTAAAAATACAGGTAGTGTTAGTGGAAAGACCACATTGCTTGTCCATGGAAGT
GTTTTGGAGGATGGAAGACCTCCTGAATAAGGAAAAAAATACTAAACAGCAAAATAAAAG
GGAACTAAAATTATGAATTAGTCTTAATTTAGTGATTATTTAAAGGATTTAACAGGAAAG
AGTCTAGAAGACTATGCAAATGTTGGTTAAAATGGAAGTAGATTTGATAAATTTGCTGCT
GTGCCTAATAATAACAACAATAATCCTTAAACTCAATAGAAAAAAGACTCTCAACCTTCC
AAAAAAATATTATAACCACTAAACAAACCCAAAGAAGCTACTAAATATGATCCTAAAAGT
AAATAATAAAATTAATAACCGTAAATGGTCATCCATAAGCCTCCTAAATAAGAATAAATT
TGGACAGAAAAGTATGCTCCAAGCAGTATTAACCTATGCATTGGAAACTAAAAGAATTAT
GAAAAAATGATGGAATGGTTGCATGATTGGGTTGAAGTTGTAATAAAGGGTAATAAAAAA
TAAGTTAAAAATTCATTTTTCAACAGAGCTTAGGGGGTACCTGATAATTCAAGTAATGTT
AATGCAAAAGCCTGCTTATTGAGTGGTCCTCCAGGAATAGGAAAAACAACATCAGTAAGA
CTTATAGCTAAGTTTATGGGATATGAAATAAGAGAATGGAATGCTTCGGATGAACGTAAT
AAAAAGAGTGTTAACAATATACTAGGAGACCTTAAATCTAACTCTATTCTAAATTTATTA
AAAAAAAATAATACAAGTGATTAAACAAACAACAAGGCTGATGATGAAGTCGAAGCTAAA
ACAAATAAAAAATTCATAATATTAATGGATGAAGTTGATGGTATGTCTTCTGGAGACAGA
GGTGGTAACCAAGCTCTTATAGATGCTATCAAAAATACAAATGTACCAATCTTTTGTATA
TGTAATGATAGGATGAATCCTAAGATTAGGAGCTTAGCAAATCACTGTTATGATATCAAG
TTTATAAAGCCAGCAAAATAAGATGTTGCAAAATATATGAAAAATGTATGTGAATAAGAA
GGATTTAAAGATGTTGAAATAGAATCATTAGAAGCAATATCAGAAAGGTTTGGAAATGAC
CTCCGTTAAACATTAAATTTTTTGGAAATGCATTTTAAGACGAGCAAGAGATTATAGGGA
ATTAATTCTAAACAACTAAATTCAGGTTAAAAGGATGCCACAGTAATGCTAGATGCATTT
TAGGCCTCAACTTAGTTGATGTAGAGTTTCAAATTCTAAAAAATGACTTTGAGAGAAAGA
ATAGAACTATTCTTTATTGATTATGATTTGATCCCACTATTAGTTCACCAAAATTATCTC
GATACTATCAAACCTAGAGAAGATGCATCTAAAAATAAAAAAAATGATAATTTTAATGTA
AAAGAACTTTAAAATCTAGTAGATGCAACTTCATCTATAGCGTAAAGTGACTTATTAAGT
AAATCTATTAGATAAAGTGGTAATTGGTCATTACTTCCAAATTTTGCTTTTACAAGTTGT
ATCTACCCATGTGATAAAGTTTGTGAAGATAAACCTATATATCCTAGATTCCCTGAATGG
CTTGGTAAGTTTTAAACAACTAAAAAAACAACAAGAGAACTAAGAGAATTCAGAGTATCT
CTCTCAAAAAGTATATCTGGCTCTAGATTTGCTGTAAAGTTTGATTATGTGCCATTTTTA
CTCAAAATTATATTGAGCCATCTAAAGAAAGGAAAAAACTCAGATATAGAGACAGTTTTA
GATTACTTAGAGTATTATAATATAAAACCCTAACACTTAAAGGAACATCTCAATGATTTA
TAATACCCAAAAAATGATTATTATGGTGTTGTATCTAGTGATATAAAGACAAAATTAACA
AAAGAATACAATAAAAGATATTCCGATAGCAGTAACAAAATAAAAACACAAAAAAAGCAA
AGCAAATCAGAACCTTCATAAGGTAAGTATGATAAAAATTTAGATGATGTCGTCTATTCA
GATACAGAAGAGTTATAATTAGATGAAAATGGGGATGTTGTTGAACCTTAGTAAGATGAA
TAAGAAAAGTCAAAGATAAAAAAACAATAATAGAAAAATAAATAAAATAATAAAAGTAAG
GCACCTAAAACTAAAAAACCTAAATCTAAAAAGAGCGGTAGCGATTCACTAACAGAAGAA
ATCAGCGAAGATGAAGATGGTTCAAACAGTTTAAATTAATTCATAGTTGATGACACCGAA
AACGATGATTGA

>TTHERM_00939110(protein)
MKKNNQSNSLLKYFSKQDTKTVNNSQNSSKDKDKEKDSKEKTKESSSKTQYKQTKEIKHE
EPKKQEQNKKQNEQKEEKEKRNFSQDIKNTRSTPIKKVQEQKKEEIKSSKNKMNVENSGT
EELSATESLTEPALSENEEKNKSSNQNKGRNVSSDNKQQQAKDVKMNQSQTRSNDNKKVD
PKQSSKKPQKKNETDDDDYGINDEEEDLPKNSKQKKLVQGSQKKNKMIVEDDDYEEKEED
KDDKELHKNSKSKRVLVKGGQKQNKMIDEDDYDAEEVDDYVEVKKTTSRTKALEEKNLKK
IEENKQKQQVSAKKDKAPPQKDKNSSNGNIDSDILAGQTIVFTGDFDGISRDTMSKIVTD
MGAKNTGSVSGKTTLLVHGSVLEDGRPPEQGKKYQTAKQKGTKIMNQSQFSDYLKDLTGK
SLEDYANVGQNGSRFDKFAAVPNNNNNNPQTQQKKDSQPSKKILQPLNKPKEATKYDPKS
KQQNQQPQMVIHKPPKQEQIWTEKYAPSSINLCIGNQKNYEKMMEWLHDWVEVVIKGNKK
QVKNSFFNRAQGVPDNSSNVNAKACLLSGPPGIGKTTSVRLIAKFMGYEIREWNASDERN
KKSVNNILGDLKSNSILNLLKKNNTSDQTNNKADDEVEAKTNKKFIILMDEVDGMSSGDR
GGNQALIDAIKNTNVPIFCICNDRMNPKIRSLANHCYDIKFIKPAKQDVAKYMKNVCEQE
GFKDVEIESLEAISERFGNDLRQTLNFLEMHFKTSKRLQGINSKQLNSGQKDATVMLDAF
QASTQLMQSFKFQKMTLRERIELFFIDYDLIPLLVHQNYLDTIKPREDASKNKKNDNFNV
KELQNLVDATSSIAQSDLLSKSIRQSGNWSLLPNFAFTSCIYPCDKVCEDKPIYPRFPEW
LGKFQTTKKTTRELREFRVSLSKSISGSRFAVKFDYVPFLLKIILSHLKKGKNSDIETVL
DYLEYYNIKPQHLKEHLNDLQYPKNDYYGVVSSDIKTKLTKEYNKRYSDSSNKIKTQKKQ
SKSEPSQGKYDKNLDDVVYSDTEELQLDENGDVVEPQQDEQEKSKIKKQQQKNKQNNKSK
APKTKKPKSKKSGSDSLTEEISEDEDGSNSLNQFIVDDTENDD

>TTHERM_00939110(gene)
ATGAAAAAGAATAACTAGTCAAATAGTTTATTGAAATATTTTAGTAAATAAGATACCAAA
ACTGTTAATAATTCGTAAAATTCTTCTAAAGACAAAGACAAAGAAAAAGATTCTAAAGAA
AAAACAAAAGAATCTTCATCTAAAACTTAATACAAATAAAGTAAATTATTTTTTTAATGA
TGATATTCTTCTACTATTTTGAAATAAAGCTAAGGAAATAAAGCATGAAGAACCTAAAAA
ATAAGAACAAAATAAGAAGCAAAATGAATAAAAGGAAGAAAAAGAAAAAAGAAATTTTAG
TTAAGATATAAAAAATACTCGATCAACTCCCATTAAAAAAGTTTAAGAGTAGAAAAAAGA
AGAAATAAAATCTTCTAAAAATAAAATGAATGTAGAGAATTCAGGAACTGAAGAATTATC
TGCCACTGAAAGTCTAACAGAACCTGCATTAAGCGAAAATGAGGAAAAAAATAAATCTTC
CAATCAAAATAAAGGGAGAAATGTTTCAAGTGATAATAAATAGTAATAAGCGAAAGACGT
AAAAATGAATTAAAGTTAGACAAGATCAAATGATAATAAAAAAGTAGATCCCAAGTAATC
AAGTAAAAAGCCATAAAAGAAAAATGAGACTGATGACGATGATTACGGTATTAATGATGA
AGAAGAGGACTTACCCAAAAATAGCAAACAAAAAAAATTAGTATAAGGGAGCCAAAAAAA
AAATAAAATGATAGTTGAAGATGATGATTATGAAGAAAAAGAAGAGGATAAAGATGATAA
GGAGTTGCATAAGAATAGTAAATCAAAAAGGGTTTTAGTAAAAGGAGGATAAAAATAAAA
TAAAATGATAGATGAAGATGACTATGATGCTGAAGAAGTAGATGATTATGTAGAAGTAAA
AAAAACTACCAGCAGGACAAAGGCTTTAGAAGAAAAGAATTTAAAAAAAATAGAAGAAAA
TAAACAAAAGTAATAAGTTTCTGCAAAAAAGGATAAAGCTCCTCCTTAAAAAGATAAAAA
TAGTTCTAATGGAAATATAGATTCTGATATTTTAGCAGGATAAACAATTGTTTTTACTGG
TGATTTTGATGGAATTTCTAGAGATACTATGTCTAAAATAGTTACAGATATGGGAGCTAA
AAATACAGGTAGTGTTAGTGGAAAGACCACATTGCTTGTCCATGGAAGTGTTTTGGAGGA
TGGAAGACCTCCTGAATAAGGAAAAAAATACTAAACAGCAAAATAAAAGGGAACTAAAAT
TATGAATTAGTCTTAATTTAGTGATTATTTAAAGGATTTAACAGGAAAGAGTCTAGAAGA
CTATGCAAATGTTGGTTAAAATGGAAGTAGATTTGATAAATTTGCTGCTGTGCCTAATAA
TAACAACAATAATCCTTAAACTCAATAGAAAAAAGACTCTCAACCTTCCAAAAAAATATT
ATAACCACTAAACAAACCCAAAGAAGCTACTAAATATGATCCTAAAAGTAAATAATAAAA
TTAATAACCGTAAATGGTCATCCATAAGCCTCCTAAATAAGAATAAATTTGGACAGAAAA
GTATGCTCCAAGCAGTATTAACCTATGCATTGGAAACTAAAAGAATTATGAAAAAATGAT
GGAATGGTTGCATGATTGGGTTGAAGTTGTAATAAAGGGTAATAAAAAATAAGTTAAAAA
TTCATTTTTCAACAGAGCTTAGGGGGTACCTGATAATTCAAGTAATGTTAATGCAAAAGC
CTGCTTATTGAGTGGTCCTCCAGGAATAGGAAAAACAACATCAGTAAGACTTATAGCTAA
GTTTATGGGATATGAAATAAGAGAATGGAATGCTTCGGATGAACGTAATAAAAAGAGTGT
TAACAATATACTAGGAGACCTTAAATCTAACTCTATTCTAAATTTATTAAAAAAAAATAA
TACAAGTGATTAAACAAACAACAAGGCTGATGATGAAGTCGAAGCTAAAACAAATAAAAA
ATTCATAATATTAATGGATGAAGTTGATGGTATGTCTTCTGGAGACAGAGGTGGTAACCA
AGCTCTTATAGATGCTATCAAAAATACAAATGTACCAATCTTTTGTATATGTAATGATAG
GATGAATCCTAAGATTAGGAGCTTAGCAAATCACTGTTATGATATCAAGTTTATAAAGCC
AGCAAAATAAGATGTTGCAAAATATATGAAAAATGTATGTGAATAAGAAGGATTTAAAGA
TGTTGAAATAGAATCATTAGAAGCAATATCAGAAAGGTTTGGAAATGACCTCCGTTAAAC
ATTAAATTTTTTGGAAATGCATTTTAAGACGAGCAAGAGATTATAGGGAATTAATTCTAA
ACAACTAAATTCAGGTTAAAAGGATGCCACAGTAATGCTAGATGCATTTTAGGCCTCAAC
TTAGTTGATGTAGAGTTTCAAATTCTAAAAAATGACTTTGAGAGAAAGAATAGAACTATT
CTTTATTGATTATGATTTGATCCCACTATTAGTTCACCAAAATTATCTCGATACTATCAA
ACCTAGAGAAGATGCATCTAAAAATAAAAAAAATGATAATTTTAATGTAAAAGAACTTTA
AAATCTAGTAGATGCAACTTCATCTATAGCGTAAAGTGACTTATTAAGTAAATCTATTAG
ATAAAGTGGTAATTGGTCATTACTTCCAAATTTTGCTTTTACAAGTTGTATCTACCCATG
TGATAAAGTTTGTGAAGATAAACCTATATATCCTAGATTCCCTGAATGGCTTGGTAAGTT
TTAAACAACTAAAAAAACAACAAGAGAACTAAGAGAATTCAGAGTATCTCTCTCAAAAAG
TATATCTGGCTCTAGATTTGCTGTAAAGTTTGATTATGTGCCATTTTTACTCAAAATTAT
ATTGAGCCATCTAAAGAAAGGAAAAAACTCAGATATAGAGACAGTTTTAGATTACTTAGA
GTATTATAATATAAAACCCTAACACTTAAAGGAACATCTCAATGATTTATAATACCCAAA
AAATGATTATTATGGTGTTGTATCTAGTGATATAAAGACAAAATTAACAAAAGAATACAA
TAAAAGATATTCCGATAGCAGTAACAAAATAAAAACACAAAAAAAGCAAAGCAAATCAGA
ACCTTCATAAGGTAAGTATGATAAAAATTTAGATGATGTCGTCTATTCAGATACAGAAGA
GTTATAATTAGATGAAAATGGGGATGTTGTTGAACCTTAGTAAGATGAATAAGAAAAGTC
AAAGATAAAAAAACAATAATAGAAAAATAAATAAAATAATAAAAGTAAGGCACCTAAAAC
TAAAAAACCTAAATCTAAAAAGAGCGGTAGCGATTCACTAACAGAAGAAATCAGCGAAGA
TGAAGATGGTTCAAACAGTTTAAATTAATTCATAGTTGATGACACCGAAAACGATGATTG
A