Identifiers and Description

Gene Model Identifier

TTHERM_00437617

Standard Name

RAD27 (5' to 3' exonuclease)

Aliases

3708.m00952

Description

flap endonuclease-1; flap endonuclease-1 PIN domain protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• nuclease activity (IEA) | GO:0004518

Biological Process

• DNA repair (IEA) | GO:0006281

Domains

• ( PF00867 ) XPG I-region
• ( PF00560 ) Leucine Rich Repeat
• ( PF00752 ) XPG N-terminal domain
• ( PF07708 ) Tash protein PEST motif
• ( PF01367 ) 5'-3' exonuclease, C-terminal SAM fold

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.5%

TetraMine Data

TTHERM_00437617

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_12460.1	9.997093137033517e-262	flap endonuclease-1 (387 aa)
Oxytricha	Contig12777.0.g42	9.996261361959507e-120	XPG I-region
WormBase	WBGene00000794	5.998625834015334e-112	locus:crn-1 Flap endonucleas e 1 status:Confirmed UniPr ot:Q9N3T2 protein_id:CCD7255 3.1
SGD	YKL113C	2.000234809436283e-103	RAD27 5 to 3 exonuclease, 5 fl ap endonuclease, required for Okazaki fragment processing an d maturation as well as for lo ng-patch base-excision repair; member of the S. pombe RAD2/F EN1 family
DictyBase	DDB_G0284987	1.9998944264638884e-101	repG on chromosome: 4 position 2762877 to 2764154
Stentor Coeruleus	SteCoe_27474	1.5400882849875202e-51

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00437617(protein)
MGIHKLMDLLKEKAPGCIKTSDLKFYAGRMIACDASMAMYQFLATTSSASDFQIQNLTDK
DGNKTGHLVGLLNRTVMLIENGLKPVWVFDGKPPQFKSGELARRQKAKDEAAEKQKTAIE
TGDMQEALKQEQRNLHITKEMKADAIKLLQLVGVPVILAPCEAEAQCAALAKAKKVFATV
TEDMDALTFATPFLLRNLNSKKEPITEINYEKMLQELKLSHNEFVDLCILCGCDYLGRIE
GVGPVNAFKLITEHKSLEKVLEHMEEVNKQSTKKQKYTVPSSYDYVSARDLFINPEVTDP
ETIQLEWKKPDVEELKKFLVEEKGFSEQRVTSQMEKVLNAKEHKGSQTRLNDFFKVQPKD
TSSTSKASKKPTNTKSANKKGGKK

>TTHERM_00437617(coding)
ATGGGAATTCATAAATTGATGGATCTATTAAAGGAGAAAGCTCCTGGATGCATTAAGACA
TCAGATCTAAAATTCTATGCTGGCCGTATGATTGCATGTGATGCCTCTATGGCAATGTAT
TAATTTTTAGCAACTACAAGCAGTGCTTCTGATTTCTAGATATAAAATTTAACAGATAAA
GATGGCAATAAAACAGGACATTTAGTTGGTTTACTTAATAGAACTGTAATGCTTATCGAA
AATGGTCTCAAGCCAGTTTGGGTTTTCGATGGTAAACCTCCTTAATTCAAGAGTGGTGAA
CTTGCAAGAAGACAAAAAGCAAAAGACGAAGCTGCTGAAAAGTAAAAAACTGCTATAGAA
ACTGGTGATATGTAAGAAGCTTTAAAGCAAGAACAACGTAATTTGCATATTACAAAAGAA
ATGAAAGCTGATGCAATAAAATTACTTTAATTGGTTGGTGTTCCAGTGATTTTAGCCCCA
TGTGAAGCAGAAGCATAATGCGCTGCTTTGGCAAAAGCTAAGAAAGTTTTTGCTACTGTT
ACTGAAGATATGGATGCTCTCACTTTTGCTACACCTTTTCTCTTGAGAAATCTCAATAGT
AAAAAGGAACCAATTACAGAAATAAACTACGAAAAGATGCTATAAGAATTAAAGTTATCT
CATAATGAATTTGTTGATTTGTGTATCTTATGTGGATGCGATTATTTAGGACGTATAGAA
GGTGTTGGCCCAGTTAATGCTTTCAAACTTATAACAGAGCACAAATCTCTAGAGAAAGTT
CTTGAACACATGGAAGAAGTTAACAAACAAAGCACTAAAAAATAAAAATATACAGTACCA
AGTTCTTATGATTATGTATCAGCAAGAGATCTTTTTATTAATCCTGAAGTTACTGATCCA
GAGACTATTTAGCTTGAATGGAAGAAACCAGATGTAGAAGAATTAAAGAAATTTTTAGTA
GAAGAAAAAGGATTTAGCGAGTAAAGAGTTACCAGTTAGATGGAAAAAGTTTTAAATGCT
AAAGAACATAAAGGTTCTTAAACCAGACTGAATGATTTCTTTAAAGTATAGCCTAAAGAT
ACATCATCAACAAGTAAGGCATCTAAAAAGCCAACAAATACTAAAAGTGCAAATAAAAAG
GGAGGAAAAAAATGA

>TTHERM_00437617(gene)
ATGGGAATTCATAAATTGATGGATCTATTAAAGGAGAAAGCTCCTGGATGCATTAAGACA
TCAGATCTAAAATTCTATGCTGGCCGTATGATTGCATGTGATGCCTCTATGGTAATCAAT
AACTAATTTAAGCATAATCTAATTATTTTATTCATATTTACTATAAATAGGCAATGTATT
AATTTTTAGCAACTACAAGCAGTGCTTCTGATTTCTAGATATAAAATTTAACAGATAAAG
ATGGCAATAAAACAGGACATTTAGTTGGTTTACTTAATAGAACTGTAATGCTTATCGAAA
ATGGTCTCAAGCCAGTTTGGGTTTTCGATGGTAAACCTCCTTAATTCAAGAGTGGTGAAG
TAATAAATAAATAAACAAATTCATTCAACATTTTTTAAAGATTGAACTTAATGAAATATT
TAAAAATATTTTTTATTTATAAGCTTGCAAGAAGACAAAAAGCAAAAGACGAAGCTGCTG
AAAAGTAAAAAACTGCTATAGAAACTGGTGATATGTAAGAAGCTTTAAAGCAAGAACAAC
GTAATTTGCATATTACAAAAGAAATGAAAGCTGATGCAATAAAATTACTTTAATTGGTTG
GTGTTCCAGTGATTTTAGCCCCATGTGAAGCAGAAGCATAATGCGCTGCTTTGGCAAAAG
CTAAGAAAGTTTTTGCTACTGTTACTGAAGATATGGATGCTCTCACTTTTGCTACACCTT
TTCTCTTGAGAAATCTCAATAGTAAAAAGGAACCAATTACAGAAATAAACTACGAAAAGA
TGCTATAAGAATTAAAGTTATCTCATAATGAATTTGTTGATTTGTGTATCTTATGTGGAT
GCGATTATTTAGGACGTATAGAAGGTGTTGGCCCAGTTAATGCTTTCAAACTTATAACAG
AGCACAAATCTCTAGAGAAAGTTCTTGAACACATGGAAGAAGTTAACAAACAAAGCACTA
AAAAATAAAAATATACAGTACCAAGTTCTTATGATTATGTATCAGCAAGAGATCTTTTTA
TTAATCCTGAAGTTACTGATCCAGAGACTATTTAGGTAAAATTGATCTTTTTTATGTAAA
TATTTATATATAAACTGTGTTTATTTATAAAAAGCTTGAATGGAAGAAACCAGATGTAGA
AGAATTAAAGAAATTTTTAGTAGAAGAAAAAGGATTTAGCGAGTAAAGAGTTACCAGTTA
GATGGAAAAAGTTTTAGTAAAATTATATTTTTTAAATTAAATAAAAATTTATTTTAAATT
AATCATAGAATGCTAAAGAACATAAAGGTTCTTAAACCAGACTGAATGATTTCTTTAAAG
TATAGCCTAAAGATACATCATCAACAAGTAAGGCATCTAAAAAGCCAACAAATACTAAAA
GTGCAAATAAAAAGGGAGGAAAAAAATGA