Identifiers and Description

Gene Model Identifier

TTHERM_00013290

Standard Name

RAD23 (RADiation sensitive 23)

Aliases

PreTt11835 | 1.m00883

Description

UBA/TS-N domain containing protein; recognizes DNA damage in nucleotide excision repair; homolog of yeast RAD23

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• damaged DNA binding (IEA) | GO:0003684

Biological Process

• proteasome-mediated ubiquitin-dependent protein catabolic process (IEA) | GO:0043161
• nucleotide-excision repair (IEA) | GO:0006289

Domains

• ( PF00627 ) UBA/TS-N domain
• ( PF00240 ) Ubiquitin family
• ( PF09280 ) XPC-binding domain
• ( PF09288 ) Fungal ubiquitin-associated domain
• ( TIGR00601 ) UV excision repair protein Rad23

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.4%

TetraMine Data

TTHERM_00013290

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02723.1	9.997093137033517e-262	UBA/TS-N domain-containing pro tein (375 aa)
Oxytricha	Contig21398.0.g83	5.0019039340728934e-39	Ubiquitin family
WormBase	WBGene00013924	7.001072473260973e-36	locus:rad-23 status:Confirme d UniProt:Q23451 protein_i d:CAA93780.2
DictyBase	DDB_G0286357	7.002785992501305e-33	rcbA on chromosome: 4 position 4412389 to 4414128
SGD	YEL037C	4.000352986427571e-28	RAD23 Protein with ubiquitin-l ike N terminus, subunit of Nuc lear Excision Repair Factor 2 (NEF2) with Rad4p that binds d amaged DNA; enhances protein d eglycosylation activity of Png 1p; also involved, with Rad4p, in ubiquitylated protein turn over
Stentor Coeruleus	SteCoe_24399	2.8625185805493937e-20

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000119
2. Ref:SUPR000121

Sequences

>TTHERM_00013290(coding)
ATGAAGATCAACATTAAGACTTTAAAGGGCACTGATTTTTTTGATGTTAACCTTGAAGAA
ACTGCTACAGTTGCTGAATTGAAGGAGAAGATTGCTACTGAAAAGTAAAAGGAAAAAGAT
ACTATTAAGTTAGTTCATAAAGGTAAATAATTGACCGAAGACTCTAAGACTCTTGGCGAA
CTTGGTATTAAAGATAATGATTTTGTTATTCTCATGTTCTTTTAAAAGAAAGCAGAAAAA
GAAGATGCTCCATAATAAGCTTAATCTGATACCACTTCTACTACCTCCGCTGCCTCAACA
ACTGCTACTAACCCCACTACTGTTCCTAAGCCTGCTGTTTCCTAACCCGCTACAACATAA
TAAACAGGAAGTTAAGGAACAGGTAGTGATCTCCTTTAAGGTCCTGAATTGGAAGCCAAA
ATTAAAGAAATTGAATCAATGGGTTTTGAAAGACCTAAGGTTCTTTAAGCTTTGAAGGCC
GCTTATTACAATCCTGAAAGAGCAGTTGATTATTTACTCAGTGGTAATATTCCTAAAGAA
CCTAGTTAATAATAGAGTCCTTTACAAGGCTTACAAGGTCCTGGTGTTGAATAATTAGCT
TAATTAGCTTAAAATCCTCAATTCCAACACATTGCTTAAGCTATTCGTTAAAACCCTGCT
CTTCTCCAACCTGTCATGTAATAATTAGCTTAAACTAACCCTGATGTTGCCAGACTTTTA
CAATAAAACCCTCAAGCTTTCTTGCAACTCCTCCTTGCTGCCTCTGAAAACGAAGGTGGA
TAAACCTTACCTCCAAATGCCATCCAAGTCACTCCTGAAGAAAAAGCTGATATTGATGAC
ATTATTTCTATGGGTTTTGATAAAAATGACGCCTTAGAAGCATATATTACCTGCGACAAG
AACAAAGAATTAGCAATTAACTATCTTTTCGAAGCAAGGGAAAGCGGTACTCTTCTTTCT
GAACACATCCAAAAGGAAGAATTAGAAGCTGCATAATAATAATCATAAAACTAAAATTAA
TAACAATAAGGTAATAACCCAAATCAATAATAATAATAAGGTGGATAAGGTGAAGGTGGT
GATAATGATGATGAAGATGACGATGATTTTATGTATTAATGA

>TTHERM_00013290(protein)
MKINIKTLKGTDFFDVNLEETATVAELKEKIATEKQKEKDTIKLVHKGKQLTEDSKTLGE
LGIKDNDFVILMFFQKKAEKEDAPQQAQSDTTSTTSAASTTATNPTTVPKPAVSQPATTQ
QTGSQGTGSDLLQGPELEAKIKEIESMGFERPKVLQALKAAYYNPERAVDYLLSGNIPKE
PSQQQSPLQGLQGPGVEQLAQLAQNPQFQHIAQAIRQNPALLQPVMQQLAQTNPDVARLL
QQNPQAFLQLLLAASENEGGQTLPPNAIQVTPEEKADIDDIISMGFDKNDALEAYITCDK
NKELAINYLFEARESGTLLSEHIQKEELEAAQQQSQNQNQQQQGNNPNQQQQQGGQGEGG
DNDDEDDDDFMYQ

>TTHERM_00013290(gene)
ATGAAGATCAACATTAAGACTTTAAAGGGCACTGATTTTTTTGATGTTAACCTTGAAGAA
ACTGCTACAGTAAATTTATTAAAATGTTTTGTTTTAGGAGAGCTCGAATTCTTGTTGACA
TTTTAAGAATTAGCTAGATAAATACTTGTTTTCAACATATTTTATAATCTTGTTAGGTTG
CTGAATTGAAGGAGAAGATTGCTACTGAAAAGTAAAAGGAAAAAGATACTATTAAGTTAG
TTCATAAAGGTAAATAATTGACCGAAGACTCTAAGACTCTTGGCGAACTTGGTATTAAAG
ATAATGATTTTGTTATTCTCATGTTCTTTTAAAAGGTAATATTATCTTAGTTTTAAGATT
TCTTCAAAATGCGGCTATCTATTTATTTCTCTTTCTATGTGTGCTTTCTTTTAATCATGA
TTAAATTAGAAAAATTCTTCAAAAAATGAAGTAAAATCAATATTTTCTTTGTCGAATTGT
ACACAATTTAATGTGACATGACACTGAAATCATCTTAGTGACTGTTAAGCATTTTAATAG
ATGAATAATAGATAAAGTAGCATAGAAAGCAGAGAAAATTTTATGGCTAGCATTTAATGA
AAGAAAGAAAGAAAGAATGAAATTGCAATTATAATTTAAAAAATAATAAACTAAATATAA
CATTATTATAGAAAGCAGAAAAAGAAGATGCTCCATAATAAGCTTAATCTGATACCACTT
CTACTACCTCCGCTGCCTCAACAACTGCTACTAACCCCACTACTGTTCCTAAGCCTGCTG
TTTCCTAACCCGCTACAACATAATAAACAGGAAGTTAAGGAACAGGTAGTGATCTCCTTT
AAGGTCCTGAATTGGAAGCCAAAATTAAAGAAATTGAATCAATGGGTTTTGAAAGACCTA
AGGTTCTTTAAGCTTTGAAGGCCGCTTATTACAATCCTGAAAGAGCAGTTGATTATTTAC
TCAGTGGTAATATTCCTAAAGAACCTAGTTAATAATAGAGTCCTTTACAAGGCTTACAAG
GTCCTGGTGTTGAATAATTAGCTTAATTAGCTTAAAATCCTCAATTCCAACACATTGCTT
AAGCTATTCGTTAAAACCCTGCTCTTCTCCAACCTGTCATGTAATAATTAGCTTAAACTA
ACCCTGATGTTGCCAGACTTTTACAATAAAACCCTCAAGCTTTCTTGCAACTCCTCCTTG
CTGCCTCTGAAAACGAAGGTGGATAAAGTAATAATTTTAAATTGTTAATTTTTCATGGAC
TTTAAATGCTAAAATAATTGACAAAAGAAAGTCTTTTACTTTTCCATTAAAGACAAAAAG
AATATAAATTCTTGTATCTGTCTTTCTTTCTTTCTATCTATTTATCTTTCTATTGATTGA
TTTAAATAATCTGATCTGATTAAAGAAAATAGAAAAGAGCAGAATTGATTAGTTAGCATA
TCTTCTTCGTTTTTCTATTTATTTTTTAATAAAAATTAATCTTTAAAATTAATTAGCCTT
ACCTCCAAATGCCATCCAAGTCACTCCTGAAGAAAAAGCTGATATTGATGACATTATTTC
TATGGGTTTTGATAAAAATGACGCCTTAGAAGCATATATTACCTGCGACAAGAACAAAGA
ATTAGCAATTAACTATCTTTTCGAAGCAAGGGAAAGCGGTACTCTTCTTTGTAAGAAATA
TTAACTTTTTTTTTTTTAATTCAAGAAAGCAAGCAAGTTTAAAAAAGCAATTGTGTATAT
AAATAAATCATTAAATTAAAATAAGAAATAGTTGAAAAAAAAGATATTCATTCATCCATT
CACATAGTAAATATTCTAAATAAATTTTTATTTAATTAAATAGCTGAACACATCCAAAAG
GAAGAATTAGAAGCTGCATAATAATAATCATAAAACTAAAATTAATAACAATAAGGTAAT
AACCCAAATCAATAATAATAATAAGGTGGATAAGGTGAAGGTGGTGATAATGATGATGAA
GATGACGATGATTTTATGTATTAATGA