Identifiers and Description

Gene Model Identifier

TTHERM_00225720

Standard Name

RAB8B (RAB GTPase 8B)

Aliases

PreTt12482 | 19.m00274

Description

RAB8B small guanosine triphosphatase family Ras-related in brain (Rab) family protein; Rab VIII family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR02528 ) ethanolamine utilization protein, EutP

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 15.6%

TetraMine Data

TTHERM_00225720

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_08923.1	4.0019235632881006e-109	Ras family protein (205 aa)
Oxytricha	Contig7494.0.g64	4.998338612125368e-60	Ras family
DictyBase	DDB_G0280043	5.997545490783615e-57	rab8A on chromosome: 3 positio n 3266503 to 3267523
WormBase	WBGene00004272	3.000458792073453e-56	locus:rab-8 status:Confirmed UniProt:G5EFC1 protein_id :CCD68351.1
SGD	YFL005W	2.000555387360374e-52	SEC4 Rab family GTPase essenti al for vesicle-mediated exocyt ic secretion and autophagy; as sociates with the exocyst comp onent Sec15p and may regulate polarized delivery of transpor t vesicles to the exocyst at t he plasma membrane
Stentor Coeruleus	SteCoe_25160	7.984904245686979e-30

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00225720(coding)
ATGTAAAGTAAATAAGACTATGATACATTAATTAAGTTACTTATCCTTGGTGATTCAGGA
GTAGGAAAAACTTGCTTTTTAGTGAATTACTGCAAAAAATCTTTTACTAGAATACATCTA
CCTACAATTGGTATTGATTATGAGCATAAATATGAAGATGTAGATGGAAAGCATGTTAAA
CTTTAAATTTGGGATACAGCTGGCCAAGAGAGGTTTAAAACTATTACTTAAAATTACTAT
AAAGGCTCTATGGGTATTATACTTGCATATAGTGTAACAGATCCTAATACCTTTAAAAAT
ATAGCAGACTGGATGAAATAAATTAGCGAAAGAGCAGATCCATCTGTTAAAATAGTAATT
ATAGCTACTAAAATTGACATGAAAGATTAAAGAAAGGTCTCAACTTAAGAAGGAGAAGAG
TTAGCTCAAAAATATGGAGTAAAATTTTTTGAAACTTCTGCTTTGGAAGGAACAAACGTC
ATAGAAGCATTTAAATGTATTGCTAGTTAAGCACTCTAAACAATTTAAGCATCTTCTCCA
ATTAATAACTTTAAAATAATTCAAAAACCTGTAATTTAATCTAAAAAATAAGAAAAAGAT
GCAAAATGTTGCTGA

>TTHERM_00225720(protein)
MQSKQDYDTLIKLLILGDSGVGKTCFLVNYCKKSFTRIHLPTIGIDYEHKYEDVDGKHVK
LQIWDTAGQERFKTITQNYYKGSMGIILAYSVTDPNTFKNIADWMKQISERADPSVKIVI
IATKIDMKDQRKVSTQEGEELAQKYGVKFFETSALEGTNVIEAFKCIASQALQTIQASSP
INNFKIIQKPVIQSKKQEKDAKCC

>TTHERM_00225720(gene)
ATGTAAAGTAAATAAGACTATGATACATTAATTAAGTTACTTATCCTTGGTGATTCAGGA
GTAGGAAAAACTTGCTTTTTAGTGAATTACTGCAAAAAATCTTTTACTAGAATACATCTA
CCTACAATTGGTATTGATTATGAGCATAAATATGAAGATGTAGATGGAAAGCATGTTAAA
CTTTAAATTTGGGATACAGCTGGCCAAGAGAGGTTTAAAACTATTACTTAAAATTACTAT
AAAGGCTCTATGGGTATTATACTTGCATATAGTGTAACAGATCCTAATACCTTTAAAAAT
ATAGCAGACTGGATGAAATAAATTAGCGAAAGAGCAGATCCATCTGTTAAAATAGTAATT
ATAGCTACTAAAATTGACATGAAAGATTAAAGAAAGGTCTCAACTTAAGAAGGAGAAGAG
TTAGCTCAAAAATATGGAGTAAAATTTTTTGAAACTTCTGCTTTGGAAGGAACAAACGTC
ATAGAAGCATTTAAATGTATTGCTAGTTAAGCACTCTAAACAATTTAAGCATCTTCTCCA
ATTAATAACTTTAAAATAATTCAAAAACCTGTAATTTAATCTAAAAAATAAGAAAAAGAT
GCAAAATGTTGCTGA