Identifiers and Description

Gene Model Identifier

TTHERM_00470810

Standard Name

RAB7 (RAB GTPase)

Aliases

56.m00199 | PreTt22495 | 3686.m00042

Description

Putative Rab GTPase; putative member of the evolutionarily conserved Rab ramily which functions in regulation of membrane trafficking

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( PF00009 ) Elongation factor Tu GTP binding
• ( TIGR02528 ) ethanolamine utilization protein, EutP
• ( PF03029 ) Conserved hypothetical ATP binding protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 14%

TetraMine Data

TTHERM_00470810

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_11358.1	5.001524836186341e-138	Ras family protein (210 aa)
WormBase	WBGene00004271	4.9994004612166366e-86	locus:rab-7 status:Confirmed UniProt:Q23146 protein_id :CAA91357.1
DictyBase	DDB_G0269236	4.001073573587828e-83	rab7A on chromosome: 1 positio n 2627248 to 2628493
Oxytricha	Contig15386.0.g21	1.0004671766404936e-76	Ras family
SGD	YML001W	6.99980278126514e-75	YPT7 Rab family GTPase; GTP-bi nding protein of the rab famil y; required for homotypic fusi on event in vacuole inheritanc e, for endosome-endosome fusio n, similar to mammalian Rab7
Stentor Coeruleus	SteCoe_33141	5.5210822770285325e-42

General Information

No Data fetched for General Information

Associated Literature

1. Ref:11387043: Stenmark H and Olkkonen VM (2001) The Rab GTPase family. Genome Biol 2(5):REVIEWS3007
2. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences

>TTHERM_00470810(protein)
MSTNKRKQLYKIIILGDSGVGKTSLMNQYVNQRFTQQYRATVGADFMAKEVTIDDRMVTL
QIWDTAGQERFQSLGGAFYRGADCCVLVYDITNKKTFENLESWKEEFKQQGCPKDPDTFP
FVVIGNKSDKASERKVETEFAQQWCKSNGDIKHFETSAKDDTNVNAAFMAIAKAASSQFQ
EDAIFFPPKPVVLQTDKAKKKEKKDDCPC

>TTHERM_00470810(coding)
ATGAGCACAAATAAAAGAAAGCAACTCTACAAGATTATCATCTTAGGTGATTCTGGTGTA
GGAAAGACTTCTCTTATGAACCAGTACGTCAACTAGCGTTTTACTCAACAATATAGAGCT
ACAGTTGGTGCTGATTTCATGGCTAAGGAAGTCACTATTGATGATCGTATGGTTACATTA
CAAATTTGGGATACCGCTGGTCAAGAACGTTTCTAATCCCTCGGTGGTGCTTTCTATAGA
GGTGCTGACTGCTGTGTTTTGGTCTATGATATTACAAATAAGAAGACCTTTGAAAACTTA
GAAAGTTGGAAAGAAGAATTTAAGCAACAAGGTTGCCCTAAAGATCCTGACACTTTCCCA
TTTGTTGTTATTGGAAATAAAAGCGATAAAGCATCAGAAAGAAAAGTTGAAACTGAGTTT
GCTCAATAATGGTGCAAATCTAATGGAGACATTAAGCACTTCGAAACATCTGCCAAGGAT
GATACTAATGTTAATGCTGCTTTTATGGCTATTGCTAAGGCTGCCTCCTCTTAATTCTAA
GAAGATGCCATCTTCTTCCCACCAAAGCCTGTTGTTTTGTAAACTGATAAGGCCAAAAAG
AAAGAAAAAAAGGATGACTGCCCTTGTTGA

>TTHERM_00470810(gene)
ATGAGCACAAATAAAAGAAAGCAACTCTACAAGATTATCATCTTAGGTGATTCTGGGTAA
ATGATCCATACTAATTCTTAATTGCAGCGATTGACATTTTTAATTATATTTCAGGATTAT
GTGCTATTTTATCAGCATAATAAGCTTGAAAATTGTGATTGTGCAGAAATTCATCTATTA
ATTTTTTTAACCCATTTTTATTAAAATAAATAGTGTAGGAAAGACTTCTCTTATGAACCA
GTAAAATGTTTTTACAGTTATTAGCATTAAAATAAATAGTTGGGCTGTTAAATAGTCTAA
AGATCAGAATAGCAGAAATTTATTTTTTTTTTTGTTTTATTACAGGTACGTCAACTAGCG
TTTTACTCAACAATATAGAGCTACAGTTGGTGCTGATTTCATGGCTAAGGAAGTCACTAT
TGATGATCGTATGGTTACATTACAAGTAATTAATATAACAAATTTTCAGTTATTTATTAA
GTTCTAGTCCAAGAATTATTTTGCCCATATGATAGAATTGTTATTTTATCTATAAAGCAG
CATTCATTTTTGCAGCAAATCTTAAATATAACTACATCATTGTTATTGATTAGTCATTAA
TAAAATTTTTAATTTTTGATAAAAATAAATATTCGTTTATAATTATTAGATTTGGGATAC
CGCTGGTCAAGAACGTTTCTAATCCCTCGGTGGTGCTTTCTATAGAGGTGCTGACTGCTG
TGTTTTGGTCTATGATATTACAAATAAGAAGGTAATTAAATAAATATTTTATGCATAAAA
TAAAGTTAGCAGAATTATAATTTGTTATCTGAAGATCTTACTTGAAGATAAATATTTACA
AATTAGCACAAGTTTTCAAATATTTTTAAATCAACATTTTTTTTATAAAAATTATTTAGA
CCTTTGAAAACTTAGAAAGTTGGAAAGAAGAATTTAAGCAACAAGGTTGCCCTAAAGATC
CTGACACTTTCCCATTTGTTGTTATTGGAAATAAAAGCGATAAAGCATCAGAAAGAAAAG
TTGAAACTGAGTTTGCTCAATAATGGTGCAAATCTAATGGAGACATTAAGCACTTCGAAA
CATCTGCCAAGGATGATACTAATGTTAATGCTGCTTTTATGGCTATTGCTAAGGCTGCCT
CCTCTTAATTCTAAGAAGATGCCATGTAATTTTACTAGAATTTAATTATTTTAGCTTGTT
CAATAGTAATGAGAAAATCAATATAAATTCACTCAATAAGTTTACATTAAATGGAGTTCA
TAATATGAAATATATAAATAAATGAATAAATGAGTATTGATTTCATCATCTAAAAAACGA
AATTTATACACAATTAAAAACAATAAATTAATACCCTATGAATAAAATATTTAACTTTAA
TCTTTAATTATTAAAAGCTTCTTCCCACCAAAGCCTGTTGTTTTGTAAACTGATAAGGCC
AAAAAGAAAGAAAAAAAGGATGACTGCCCTTGTTGA