Identifiers and Description

Gene Model Identifier

TTHERM_00083670

Standard Name

RAB65 (RAB GTPase 65)

Aliases

PreTt16314 | 6.m00388 | 3836.m01984

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 13.2%

TetraMine Data

TTHERM_00083670

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02392.1	9.996373193201036e-79	Ras family protein (221 aa)
SGD	YFL005W	7.998505003885351e-50	SEC4 Rab family GTPase essenti al for vesicle-mediated exocyt ic secretion and autophagy; as sociates with the exocyst comp onent Sec15p and may regulate polarized delivery of transpor t vesicles to the exocyst at t he plasma membrane
WormBase	WBGene00004273	9.999142814001536e-47	locus:rab-10 status:Confirme d UniProt:Q94148 protein_i d:CCD70773.1
DictyBase	DDB_G0280043	9.999142814001536e-47	rab8A on chromosome: 3 positio n 3266503 to 3267523
Oxytricha	Contig11247.0.g57	3.998479955315009e-46	Ras family
Stentor Coeruleus	SteCoe_15778	5.242885663363464e-22

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00083670(coding)
ATGAGTTAGAATAAGGATGATTAGCAAATTTATTTTAAAATATTAATGATAGGCAACTCA
GCAGTTGGAAATACATGTCTATTGGTGAGATATTGCAATAGTGAATTTCCAAATAGTAGC
ATAATCACATTGGGTATAGATTTAAAAATAAAAAAACTTGAAATTAATAAAAAAAAGCTT
AATTTGCATATTTTGGATACAGCTAGTTAGGATAAATTTAGAACCATTACTCCAAATTAT
TTCAAAGCAGCTCATGGTATTTTAGTAGCCTATTCAGTAGAAGACTAAGAATCGTTTGAG
AAAGTAGGAAGCTGGATTTAATGCATAAAAGAAAATTTCGATAATGCTAATATATCTATA
TTATTAGTTGGAAATAAATCTGATTCAAAACAAAGAGTAGTTTCATTAGAATAGGGTGAA
AAGCTTGCTGAGTAATATAATATTCCTTTTTAGGAAACTAGTGCTCTTAATAATATTAAT
GTGAGCGAATCTTTTTATTAACTTGCTAAAATGTGCTTAGATTAGTATGAGATAAAAAGT
TCTACTAGGTCTCCTTAATCTATTGTACCAAAGAAAAAATAAGAAAATGGAGAAACTAAA
AAAAATTGTTGTTGA

>TTHERM_00083670(protein)
MSQNKDDQQIYFKILMIGNSAVGNTCLLVRYCNSEFPNSSIITLGIDLKIKKLEINKKKL
NLHILDTASQDKFRTITPNYFKAAHGILVAYSVEDQESFEKVGSWIQCIKENFDNANISI
LLVGNKSDSKQRVVSLEQGEKLAEQYNIPFQETSALNNINVSESFYQLAKMCLDQYEIKS
STRSPQSIVPKKKQENGETKKNCC

>TTHERM_00083670(gene)
ATTAAAATTCAAAAAATAAATATACTTGAAAAGAAAGTAAAGTAAAAGGTTATTTGTGAA
AAATTGATTTATGAGTTAGAATAAGGATGATTAGCAAATTTATTTTAAAATATTAATGAT
AGGCAACTCAGCAGTTGGAAATACATGTCTATTGGTGAGATATTGCAATAGTGAATTTCC
AAATAGTAGCATAATCACATTGGGTATTGTATTTATTGATTATTTTAAAATTAAAAAAAT
AATGATCTAATTCAAAAAAATATAAACATGTAAAAGTAAATTTCTTTGTTAATAAAAAGG
TATAGATTTAAAAATAAAAAAACTTGAAATTAATAAAAAAAAGCTTAATTTGCATATTTT
GGATACAGCTAGTTAGGATAAATTTAGAACCATTACTCCAAATTATTTCAAAGCAGCTCA
TGGTATTTTAGTAGCCTATTCAGTAGAAGACTAAGAATCGTTTGAGAAAGTAGGAAGCTG
GATTTAATGCATAAAAGAAAATTTCGATAATGCTAATATATCTATATTATTAGTTGGAAA
TAAATCTGATTCAAAACAAAGAGTAGTTTCATTAGAATAGGGTGAAAAGCTTGCTGAGTA
ATATAATATTCCTTTTTAGGAAACTAGTGCTCTTAATAATATTAATGTGAGCGAATCTTT
TTATTAACTTGCTAAAATGTGCTTAGATTAGTATGAGATAAAAAGTTCTACTAGGTCTCC
TTAATCTATTGTACCAAAGAAAAAATAAGAAAATGGAGAAACTAAAAAAAATTGTTGTTG
A