Identifiers and Description

Gene Model Identifier

TTHERM_00334520

Standard Name

RAB5B

Aliases

PreTt05997 | 34.m00234 | 3689.m00032

Description

Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( PF00009 ) Elongation factor Tu GTP binding
• ( TIGR00650 ) GTP-binding conserved hypothetical protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.7%

TetraMine Data

TTHERM_00334520

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_16044.1	6.001241942754875e-123	small GTP-binding protein doma in-containing protein (205 aa)
Oxytricha	Contig22448.0.g39	4.998711177326993e-55	Ras family
WormBase	WBGene00004268	2.998863950472602e-38	locus:rab-5 status:Partially _confirmed UniProt:P91857 protein_id:CAB04205.1
SGD	YOR089C	2.998863950472602e-38	VPS21 Rab family GTPase requir ed for endocytic transport and for sorting of vacuolar hydro lases; localized in endocytic intermediates; detected in mit ochondria; geranylgeranylation required for membrane associa tion; mammalian Rab5 homolog
DictyBase	DDB_G0289827	3.0001084582952455e-37	rab18 on chromosome: 5 positio n 3292859 to 3293559
Stentor Coeruleus	SteCoe_28677	1.0530617357553812e-20

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00334520(coding)
ATGAGTAAAAAATAGAATAAAGATAGTGGAGGTGGTTGCTGTGGCGGCAGTAGCAGCTCA
AACAATTCAGTATAAAAGCCATTAAATACAAAAAAAAAAGAAATTAAGGTAGTATTATTA
GGTGACCCTAATGTAGGAAAAAGTTCTATTGCGTTGAGATATTGCAAGCATTAATTTAGT
GAAACATATGAGCTCACAATAGGAGGTGTTTATAATTTAAAAGAGACTACATTATCTAAC
GGATAAAAAGTTGCAATTCACCTTTGGGATACTGGTGGTGAAGAAAAATTTAGATCAATG
ACCCAGTTATATTATAATGACGCTTAAGCAGCTATTTTAGTTTATGATGTCTAAAATGCA
TAAACATTTTAAAGTTTAGAGTATTGGTTAAAAGAATTAGAAAATAAAGTTTCTAATTAA
GGAATGATATTGTGTATAGCTGGAAATAAATGTGATGTGGATGAAGATTTGAGAGCTGTA
ACCTACGATTAAGGAGCTTAATTTTGTAAAAATAATAATAATATAATATTTGCTGAAACA
TCAGCAAAAACAAATTAAGGAATTGATGACCTCTTTAATGAATTGTTAGAAAAGATATAA
AATAAACTATGA

>TTHERM_00334520(protein)
MSKKQNKDSGGGCCGGSSSSNNSVQKPLNTKKKEIKVVLLGDPNVGKSSIALRYCKHQFS
ETYELTIGGVYNLKETTLSNGQKVAIHLWDTGGEEKFRSMTQLYYNDAQAAILVYDVQNA
QTFQSLEYWLKELENKVSNQGMILCIAGNKCDVDEDLRAVTYDQGAQFCKNNNNIIFAET
SAKTNQGIDDLFNELLEKIQNKL

>TTHERM_00334520(gene)
ATGAGTAAAAAATAGAATAAAGATAGTGGAGGTGGTTGCTGTGGCGGCAGTAGCAGCTCA
AACAATTCAGTATAAAAGCCATTAAATACAAAAAAAAAAGAAATTAAGGTAGTATTATTA
GGTGACCCTAATGTAGGAAAAAGTTCTATTGCGTTGAGATATTGCAAGCATTAATTTAGT
GAAACATATGAGCTCACAATAGGAGGTGTTTATAATTTAAAAGAGACTACATTATCTAAC
GGATAAAAAGTTGCAATTCACCTTTGGGATACTGGTGGTGAAGAAAAATTTAGGTAAAAT
TTATTTTGCTTTCCAAATTATTAATAACAAACAGACACACACAGTAAAATGAAATAACAG
AATAAAATGTTATATTGCTGAAAATTTATTACAAATTTAATTTAAGAAAGTAAAAAATAT
AAAATAAATTTAAATAGATCAATGACCCAGTTATATTATAATGACGCTTAAGCAGCTATT
TTAGTTTATGATGTCTAAAATGCATAAACATTTTAAAGTTTAGAGTATTGGTTAAAAGAA
TTAGAAAATAAAGTTTCTAATTAAGGAATGATATTGTGTATAGCTGGAAATAAATGTGAT
GTGGATGAAGATTTGAGAGCTGTAACCTACGATTAAGGAGCTTAATTTTGTAAAAATAAT
AATAATATAATATTTGCTGAAACATCAGCAAAAACAAATTAAGGAATTGATGACCTCTTT
AATGAATTGTTAGAAAAGATATAAAATAAACTATGA