Identifiers and Description

Gene Model Identifier

TTHERM_00727520

Standard Name

RAB59 (RAB GTPase 59)

Aliases

PreTt07253 | 118.m00081 | 3739.m00004

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00727520

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17907.1	1.000434858898539e-105	small GTP-binding protein doma in-containing protein (185 aa)
DictyBase	DDB_G0277867	3.998097515166115e-39	rab1B on chromosome: 3 positio n 743092 to 744234
Oxytricha	Contig15751.0.0.g87	8.003017249547689e-39	Ras family
SGD	YFL038C	2.00017271388466e-38	YPT1 Rab family GTPase, involv ed in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by prote in geranylgeranyltransferase t ype II (Bet2p-Bet4p)
WormBase	WBGene00004284	1.999002769139511e-37	locus:rab-35 status:Confirme d UniProt:Q9U2C3 protein_i d:CAB57899.1
Stentor Coeruleus	SteCoe_15778	1.5628821893349888e-18

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00727520(coding)
ATGTCTCAAATATCATAGCCATAATAAAATCAAAAAGAATAGTACGACTTCATGGTGAAA
GTAGTTTTAGTAGGTGATGAAGGAGTAGGTAAAACATAAATATCGAGGAGAATAGCAGGT
TTATAATATAACGAAAAGCATACTCCAACTATTGGAGTAGATTTCAAAGTTAAAACTATG
TAAGTAGGCAATAACATTATGAAATTTTAAGTATGGGATACTGCTGGCATACCTAAATAT
CGTGTATCAAATAAAGCTTAATACTCAGGAGCCGCTGCTGTTATAGTTATATTTAGCTTT
AATGATCTATAAAGCTTTGAGAGTGTTGAGAAATGGATATAAGAAATAAATTTTGAAAAT
TAGGATAGCTAAATAGTAAGAGTTTTAGTTGGAAATAAATGTGATTTTTAAAAGGAAGGA
AGATATGCCACTCCTATGGCTGCTGAATAATTAGCAAAGAGAAATAATATGGAATATATT
GAAGTATCTGCTAAAGAAAACCATAACGTTAGAGAGCTTTTCTAATTAGTAGGTTAACAA
ATATATAAAGAATTAATTGATCCTTAATGA

>TTHERM_00727520(protein)
MSQISQPQQNQKEQYDFMVKVVLVGDEGVGKTQISRRIAGLQYNEKHTPTIGVDFKVKTM
QVGNNIMKFQVWDTAGIPKYRVSNKAQYSGAAAVIVIFSFNDLQSFESVEKWIQEINFEN
QDSQIVRVLVGNKCDFQKEGRYATPMAAEQLAKRNNMEYIEVSAKENHNVRELFQLVGQQ
IYKELIDPQ

>TTHERM_00727520(gene)
ATGTCTCAAATATCATAGCCATAATAAAATCAAAAAGAATAGTACGACTTCATGGTGAAA
GTAGTTTTAGTAGGTGATGAAGGAGTAGGTAAAACATAAATATCGAGGAGAATAGCAGGT
TTATAATATAACGAAAAGCATACTCCAACTATTGGAGTAGATTTCAAAGTTAAAACTATG
TAAGTAGGCAATAACATTATGAAATTTTAAGTATGGGATACTGCTGGCATACCTAAATAT
CGTGTATCAAATAAAGCTTAATACTCAGGAGCCGCTGCTGTTATAGTTATATTTAGCTTT
AATGATCTATAAAGCTTTGAGAGTGTTGAGAAATGGATATAAGAAATAAATTTTGAAAAT
TAGGATAGCTAAATAGTAAGAGTTTTAGTTGGAAATAAATGTGATTTTTAAAAGGAAGGA
AGATATGCCACTCCTATGGCTGCTGAATAATTAGCAAAGAGAAATAATATGGAATATATT
GAAGTATCTGCTAAAGAAAACCATAACGTTAGAGAGCTTTTCTAATTAGTAGGTTAACAA
ATATATAAAGAATTAATTGATCCTTAATGA