Identifiers and Description

Gene Model Identifier

TTHERM_01041920

Standard Name

RAB58 (RAB GTPase 58)

Aliases

PreTt01808 | 207.m00052

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00073 ) hydrogenase accessory protein HypB
• ( PF00009 ) Elongation factor Tu GTP binding

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 13%

TetraMine Data

TTHERM_01041920

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_01158.1	3.999751664085691e-132	Ras family protein (219 aa)
Oxytricha	Contig15751.0.0.g87	1.0002546821282671e-50	Ras family
WormBase	WBGene00004266	6.001950283815408e-48	locus:rab-1 status:Confirmed UniProt:Q9UAQ6 protein_id :CCD67094.1
DictyBase	DDB_G0277867	5.000307300873256e-47	rab1B on chromosome: 3 positio n 743092 to 744234
SGD	YFL038C	5.002382393859839e-46	YPT1 Rab family GTPase, involv ed in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by prote in geranylgeranyltransferase t ype II (Bet2p-Bet4p)
Stentor Coeruleus	SteCoe_36857	3.873997628687187e-21

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_01041920(coding)
ATGAACGGCGGCGCTAGTGACGGTATTGCTAAAGTTAAAATCCTAACATTAGGTGAATCA
GGTGTAGGAAAATCTTCGTTGTTACTTAGATACAAAGACGACAAATTCGCAGGAAACTTC
GTTACAACTCTTGGAGTTGAATATAAATAAAAGCAGATTCAAATTGAAAATATTCCTCTT
ACAGTCTAAGTTTGGGATACTGCTGGTTAAGAACGTTTTAAGACAATAACTCCAAATTAC
TACAGGTCAGTCGACGGTGCTCTTCTTGTTTTTGATATTTCAGAGTTAGAAACCTTCGAC
AAAATCGAATACTGGATCTAAGATCTACAGAAAGATGCTGACCTCACAAAAGTAATTATG
GTTTTAGTAGGCAATAAGAGTGATTTAGAAGAAAAAAGAAAAGTAGATTTTTAGACTGCC
CAAAAAAAGGCTTAGGAATATTAAATAGAATACATAGAAACTTCAGCCAAAACCAATTCA
AATGTTGATCAAGTTTTTGAAATGATTGTTAGAAAAGTTATAGATAAAAAAGGCGGCATT
GAAAAATTTAAAGCTCAATATTAAGAATAAATCGCATAAAACCTTAACTTAAAGAAAGCT
AACACTTCCAATGGTGCTTCTGGATCCAATAAAAACAAATAAAACAACAACAATGGTGGC
TGTTGTTGA

>TTHERM_01041920(protein)
MNGGASDGIAKVKILTLGESGVGKSSLLLRYKDDKFAGNFVTTLGVEYKQKQIQIENIPL
TVQVWDTAGQERFKTITPNYYRSVDGALLVFDISELETFDKIEYWIQDLQKDADLTKVIM
VLVGNKSDLEEKRKVDFQTAQKKAQEYQIEYIETSAKTNSNVDQVFEMIVRKVIDKKGGI
EKFKAQYQEQIAQNLNLKKANTSNGASGSNKNKQNNNNGGCC

>TTHERM_01041920(gene)
ATGAACGGCGGCGCTAGTGACGGTATTGCTAAAGTTAAAATCCTAACATTAGGTGAATCA
GGTGTAGGAAAATCTTCGTTGTTACTTAGATACAAAGACGACAAATTCGCAGGAAACTTC
GTTACAACTCTTGGAGTTGAATATAAATAAAAGCAGATTCAAATTGAAAATATTCCTCTT
ACAGTCTAAGTTTGGGATACTGCTGGTTAAGAACGTTTTAAGACAATAACTCCAAATTAC
TACAGGTCAGTCGACGGTGCTCTTCTTGTTTTTGATATTTCAGAGTTAGAAACCTTCGAC
AAAATCGAATACTGGATCTAAGATCTACAGAAAGATGCTGACCTCACAAAAGTAATTATG
GTTTTAGTAGGCAATAAGAGTGATTTAGAAGAAAAAAGAAAAGTAGATTTTTAGACTGCC
CAAAAAAAGGCTTAGGAATATTAAATAGAATACATAGAAACTTCAGCCAAAACCAATTCA
AATGTTGATCAAGTTTTTGAAATGATTGTTAGAAAAGTTATAGATAAAAAAGGCGGCATT
GAAAAATTTAAAGCTCAATATTAAGAATAAATCGCATAAAACCTTAACTTAAAGAAAGCT
AACACTTCCAATGGTGCTTCTGGATCCAATAAAAACAAATAAAACAACAACAATGGTGGC
TGTTGTTGA