Identifiers and Description

Gene Model Identifier

TTHERM_00201700

Standard Name

RAB50 (RAB GTPase 50)

Aliases

PreTt13741 | 17.m00348

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00157 ) ribosome small subunit-dependent GTPase A
• ( TIGR00650 ) GTP-binding conserved hypothetical protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11%

TetraMine Data

TTHERM_00201700

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_41344.1	9.997975313387782e-28	hypothetical protein (168 aa)
Oxytricha	Contig6560.0.g89	4.999245259173412e-21	Ras family
WormBase	WBGene00004276	1.000116773704384e-19	locus:rab-14 status:Confirme d UniProt:Q93874 protein_i d:CAB01884.1
DictyBase	DDB_G0281337	4.998394530072393e-19	rab14 on chromosome: 3 positio n 4383385 to 4384571
SGD	YFL005W	4.997543945741262e-17	SEC4 Rab family GTPase essenti al for vesicle-mediated exocyt ic secretion and autophagy; as sociates with the exocyst comp onent Sec15p and may regulate polarized delivery of transpor t vesicles to the exocyst at t he plasma membrane

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00201700(coding)
ATGTTTGCTAAAAAAGGCAGTTAATAAAAAAGTATAATATGTATTTCTGTAGGAGATGCA
AATGTTGGAAAATCTTCTATATTTGCAAGGCAATTTTATGGAGAGGTTCCTCAATAAAAT
TCCCTCTATGTTGATTATTCAACCATATTGGTGAGAAAAGGAAATGAAGAGATTTAATTT
AAATTTTGGGTCATAAATCACCTTCACAAACATTTAACATCATAATATTATAGAACTTCT
ATTTTAATTATGATTTACGATATTACAAGCAGAGACTCATTTACACATATTTAATATTAT
TATGAAGATTATGTTAAAAAATGTAATATAAAATCAATAATTGCTCTTGTTGGAAATAAG
AAGGATCTAAATGAGTTTAGATAAGTTTCATTTTAGGAGGGTTAAGATCTAGCCAAATCA
TTAGGTGTAGATTTTTTTGAAGTATCTGCTTTTACAGGTGATAAAGTAAAAGATTTGTAT
GACTTTTTAATAAACTAGTCTTTTGATACAGCTAATTTTGAATGA

>TTHERM_00201700(protein)
MFAKKGSQQKSIICISVGDANVGKSSIFARQFYGEVPQQNSLYVDYSTILVRKGNEEIQF
KFWVINHLHKHLTSQYYRTSILIMIYDITSRDSFTHIQYYYEDYVKKCNIKSIIALVGNK
KDLNEFRQVSFQEGQDLAKSLGVDFFEVSAFTGDKVKDLYDFLINQSFDTANFE

>TTHERM_00201700(gene)
ATGTTTGCTAAAAAAGGCAGTTAATAAAAAAGTATAATATGTATTTCTGTAGGAGATGCA
AATGTTGGAAAATCTTCTATATTTGCAAGGCAATTTTATGGAGAGGTTCCTCAATAAAAT
TCCCTCTATGTTGATTATTCAACCATATTGGTGAGAAAAGTAAAATACATATTTCAAATT
TAGTTTTTTTAGTAGATTTTAAACATTTTAGGGAAATGAAGAGATTTAATTTAAATTTTG
GGTCATAAATCACCTTCACAAACATTTAACATCATAATATTATAGAACTTCTATTTTAAT
TATGATTTACGATATTACAAGCAGAGACTCATTTACACATATTTAATATTATTATGAAGA
TTATGTTAAAAAATGTAATATAAAATCAATAATTGCTCTTGTTGGAAATAAGAAGGATCT
AAATGAGTTTAGATAAGTTTCATTTTAGGAGGGTTAAGATCTAGCCAAATCATTAGGTGT
AGATTTTTTTGAAGTATCTGCTTTTACAGGTGATAAAGTAAAAGATTTGTATGACTTTTT
AATAAACTAGTCTTTTGATACAGCTAATTTTGAATGA