Identifiers and Description

Gene Model Identifier

TTHERM_00201690

Standard Name

RAB49 (RAB GTPase 49)

Aliases

PreTt13740 | 17.m00347

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00073 ) hydrogenase accessory protein HypB

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11%

TetraMine Data

TTHERM_00201690

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_01991.1	1.000382677035467e-28	hypothetical protein (178 aa)
DictyBase	DDB_G0292406	8.999890565246037e-26	rab4 on chromosome: 6 position 1558648 to 1559514
Oxytricha	Contig5831.0.g6	9.996273942859018e-26	Ras family
WormBase	WBGene00019317	1.0004572433669413e-23	status:Confirmed UniProt:Q21 137 protein_id:CCD72274.1
SGD	YFL005W	5.0000961330688895e-23	SEC4 Rab family GTPase essenti al for vesicle-mediated exocyt ic secretion and autophagy; as sociates with the exocyst comp onent Sec15p and may regulate polarized delivery of transpor t vesicles to the exocyst at t he plasma membrane

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00201690(coding)
ATGTCTGCTAAAAACGACAGTAAATAAAAAATTATAAAATGTGCTTCAGTGGGAGATTAA
TTTGTTGGAAAATCTGCTCTATTTGTTAGGTAATTTCATGGAAAGTTTCTTCGATAAAAA
ACCGCTGGAGTTGATTTTTAAATTTTCGTTCTGAAAAAAGGAAATGAAGAAATTAAATTT
TAGTTTTGGGATTTAGGTTATAGGAGTAGATAAGAAGGATTAAAAGTTTATCCTTAAACT
TCTATTTTAATTATGATTTATGATATTACAAACAGAATCTCTTTTACAAATATTTAAAAA
TATTATGGAGATTATGTTAGATAAGGAAATAAAAAATCAATAATTGCTCTTGTCGGAAAT
AAGAAGGATCTAAATGAATATAGAGAAGTTTCATTTTTGGAAGGTTAAGAGCTGGGTAAA
TAGTTAGGTGTATATTTTTTTGAAGTATCTGCTTTTACAGGTGAAAATGTTAAAGATTTG
TATGAGTTCTTAATAGATAAGTCTATTGATACAGTCTAATTTTGA

>TTHERM_00201690(protein)
MSAKNDSKQKIIKCASVGDQFVGKSALFVRQFHGKFLRQKTAGVDFQIFVLKKGNEEIKF
QFWDLGYRSRQEGLKVYPQTSILIMIYDITNRISFTNIQKYYGDYVRQGNKKSIIALVGN
KKDLNEYREVSFLEGQELGKQLGVYFFEVSAFTGENVKDLYEFLIDKSIDTVQF

>TTHERM_00201690(gene)
ATGTCTGCTAAAAACGACAGTAAATAAAAAATTATAAAATGTGCTTCAGTGGGAGATTAA
TTTGTTGGAAAATCTGCTCTATTTGTTAGGTAATTTCATGGAAAGTTTCTTCGATAAAAA
ACCGCTGGAGTTGATTTTTAAATTTTCGTTCTGAAAAAAGTAAAATAAATATTTCGAATT
TATTTTTTTTAATAGATTTTATACATTTTAGGGAAATGAAGAAATTAAATTTTAGTTTTG
GGATTTAGGTTATAGGAGTAGATAAGAAGGATTAAAAGTTTATCCTTAAACTTCTATTTT
AATTATGATTTATGATATTACAAACAGAATCTCTTTTACAAATATTTAAAAATATTATGG
AGATTATGTTAGATAAGGAAATAAAAAATCAATAATTGCTCTTGTCGGAAATAAGAAGGA
TCTAAATGAATATAGAGAAGTTTCATTTTTGGAAGGTTAAGAGCTGGGTAAATAGTTAGG
TGTATATTTTTTTGAAGTATCTGCTTTTACAGGTGAAAATGTTAAAGATTTGTATGAGTT
CTTAATAGATAAGTCTATTGATACAGTCTAATTTTGA