Identifiers and Description

Gene Model Identifier

TTHERM_00209270

Standard Name

RAB46 (RAB GTPase 46)

Aliases

PreTt13805 | 17.m00412

Description

RAB46 Ras family small GTPase; Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10%

TetraMine Data

TTHERM_00209270

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Oxytricha	Contig5831.0.g6	5.002276765025871e-34	Ras family
Tetrahymena borealis	EI9_01991.1	2.0003218023735366e-33	hypothetical protein (178 aa)
DictyBase	DDB_G0272138	9.000751454575209e-33	rab2B on chromosome: 2 positio n 1483407 to 1484594
SGD	YOR089C	3.00033207980219e-32	VPS21 Rab family GTPase requir ed for endocytic transport and for sorting of vacuolar hydro lases; localized in endocytic intermediates; detected in mit ochondria; geranylgeranylation required for membrane associa tion; mammalian Rab5 homolog
WormBase	WBGene00004268	9.99967697349061e-30	locus:rab-5 status:Partially _confirmed UniProt:P91857 protein_id:CAB04205.1
Stentor Coeruleus	SteCoe_38174	0.00000000000003442477108469977

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00209270(coding)
ATGATTCATCAAACAGAGTAGTATAAAATTATGAAAGTAGCTTAAATAGGAGGTGGGTAT
ACAGGAAAGTCATCTTTATATTTGAGATATCTTTAAGGAGAGTTTATTGACAACCCTAAT
TATATTGGCGTTGAATTTTATACAAAAACTATTAAGATAGCAGAGGAACAAATTAAATTT
TAATTTTGGGATTGTCACTTGAACGAAAAAATCTATTCTTTATATCAAAATTATTTTAAA
TAATGTTCAATAGTTATGATATCTTATGACATTACTAATAGATACTCCTTTGATAGAGCG
CAATTATGGTGTAAAGATTACAATTAAAAAAAATTAAATAAAGTAGCTCTACTAGCTTTG
ATTGGAAATAAATGCGATTTAGAATAATAAAGGTAAGTTTCATATCAAGAGGGTAAACAT
ATTGCAAAGTCTTTAGGAATGCTATTCTTCGAAGTCTCCTCTAAAACAGGTTATTAAGTA
AATGAGCTGTTTGAAAGTTTAATAAGCTACGTGATCAATATTAATTGA

>TTHERM_00209270(protein)
MIHQTEQYKIMKVAQIGGGYTGKSSLYLRYLQGEFIDNPNYIGVEFYTKTIKIAEEQIKF
QFWDCHLNEKIYSLYQNYFKQCSIVMISYDITNRYSFDRAQLWCKDYNQKKLNKVALLAL
IGNKCDLEQQRQVSYQEGKHIAKSLGMLFFEVSSKTGYQVNELFESLISYVININ

>TTHERM_00209270(gene)
ATGATTCATCAAACAGAGTAGTATAAAATTATGAAAGTAGCTTAAATAGGAGGTGGGTAT
ACAGGAAAGTCATCTTTATATTTGAGATATCTTTAAGGAGAGTTTATTGACAACCCTAAT
TATATTGGCGTTGAATTTTATACAAAAACTATTAAGATAGTAAAAATTAATTATTCTACA
AAATCTAAATAAAAATGTTTGATTTTATTTTTAATAGGCAGAGGAACAAATTAAATTTTA
ATTTTGGGATTGTCACTTGAACGAAAAAATCTATTCTTTATATCAAAATTATTTTAAATA
ATGTTCAATAGTTATGATATCTTATGACATTACTAATAGATACTCCTTTGATAGAGCGCA
ATTATGGTGTAAAGATTACAATTAAAAAAAATTAAATAAAGTAGCTCTACTAGCTTTGAT
TGGAAATAAATGCGATTTAGAATAATAAAGGTAAGTTTCATATCAAGAGGGTAAACATAT
TGCAAAGTCTTTAGGAATGCTATTCTTCGAAGTCTCCTCTAAAACAGGTTATTAAGTAAA
TGAGCTGTTTGAAAGTTTAATAAGCTACGTGATCAATATTAATTGA