Identifiers and Description

Gene Model Identifier

TTHERM_00664060

Standard Name

RAB41 (RAB GTPase 41)

Aliases

PreTt23853 | 98.m00196 | 3736.m00094

Description

Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( PF00009 ) Elongation factor Tu GTP binding
• ( TIGR00650 ) GTP-binding conserved hypothetical protein

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.1%

TetraMine Data

TTHERM_00664060

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_17189.1	2.0000211193600847e-137	Ras family protein (238 aa)
Oxytricha	Contig15751.0.0.g87	1.0001801308941382e-55	Ras family
DictyBase	DDB_G0271736	9.998397555368434e-52	rabC on chromosome: 2 position 718547 to 719569
WormBase	WBGene00004266	8.003782782428492e-46	locus:rab-1 status:Confirmed UniProt:Q9UAQ6 protein_id :CCD67094.1
SGD	YFL038C	1.000159011384939e-43	YPT1 Rab family GTPase, involv ed in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by prote in geranylgeranyltransferase t ype II (Bet2p-Bet4p)
Stentor Coeruleus	SteCoe_14213	1.9287498479639178e-22

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00664060(coding)
ATGTAAAAAGAAAATAGTGGGGTTTATTCAAATTAGCTTTAAGCTGGAGTTTTTAATTCC
CCACACACGAAGATTGACTTAGTTTTTAAAATAATTTTAATAGGACAGCAAAATGTAGGC
AAATCTTCCATTTTAAATTAGTACGTAGATAGAGAATTTGCAGAACATTATATGTCAACA
ATAGGTGTAGATTTTAGATTAAAAACAATTAAAACAAGTTCTGGTAAAATAGTGAAGCTA
CAAATTTGGGATACTGCTGGATAAGAAAGATTTGCAGCTTTGACTAATTCACATTATAAA
GGAGCGCATTCTTGCATTTGTGTCTATGATATAACTAATCCTAAGAGCTTAGCATCAGCA
GAATAATATTTATAGACAACAATTAACCAACATGGGATAGATTCAGATTTAATTTATCTG
ATAGGCAACAAATCAGATTTAGAAGATTAAAGGAAGATTAGCGAAAAAGAAGGAAAAGAT
TTAAGTTATAAATACGGAGTAAATTTCTTAGAAACAAGTGCAAAAAATTACTTAAATATA
GAAGAGCTTTTTGATTAGATGGTTGAGCACTTAGTGAGTCTAATTACTAACCCTCAAATA
CCAAAAAAACTTTCATAGTTAAATAATGTCAAAATAACTAGCAAAGATATTATGATTAAA
TAGTAAGAAGGTAATAATGAAGTTTAAAAGAAAGGCTGCTGTTGA

>TTHERM_00664060(protein)
MQKENSGVYSNQLQAGVFNSPHTKIDLVFKIILIGQQNVGKSSILNQYVDREFAEHYMST
IGVDFRLKTIKTSSGKIVKLQIWDTAGQERFAALTNSHYKGAHSCICVYDITNPKSLASA
EQYLQTTINQHGIDSDLIYLIGNKSDLEDQRKISEKEGKDLSYKYGVNFLETSAKNYLNI
EELFDQMVEHLVSLITNPQIPKKLSQLNNVKITSKDIMIKQQEGNNEVQKKGCC

>TTHERM_00664060(gene)
ATGTAAAAAGAAAATAGTGGGGTTTATTCAAATTAGCTTTAAGCTGGAGTTTTTAATTCC
CCACACACGAAGATTGACTTAGTTTTTAAAATAATTTTAATAGGACAGCAAAATGTAGGC
AAATCTTCCATTTTAAATTAGTACGTAGATAGAGAATTTGCAGAACATTATATGTCAACA
ATAGGTGTAGATTTTAGATTAAAAACAATTAAAACAAGTTCTGGTAAAATAGTGAAGCTA
CAAATTTGGGATACTGCTGGATAAGAAAGATTTGCAGCTTTGACTAATTCACATTATAAA
GGAGCGCATTCTTGCATTTGTGTCTATGATATAACTAATCCTAAGAGCTTAGCATCAGCA
GAATAATATTTATAGACAACAATTAACCAACATGGGATAGATTCAGATTTAATTTATCTG
ATAGGCAACAAATCAGATTTAGAAGATTAAAGGAAGATTAGCGAAAAAGAAGGAAAAGAT
TTAAGTTATAAATACGGAGTAAATTTCTTAGAAACAAGTGCAAAAAATTACTTAAATATA
GAAGAGCTTTTTGATTAGATGGTTGAGCACTTAGTGAGTCTAATTACTAACCCTCAAATA
CCAAAAAAACTTTCATAGTTAAATAATGTCAAAATAACTAGCAAAGATATTATGATTAAA
TAGTAAGAAGGTAATAATGAAGTTTAAAAGAAAGGCTGCTGTTGA