Identifiers and Description

Gene Model Identifier

TTHERM_00540100

Standard Name

RAB21A

Aliases

PreTt12168 | 70.m00164 | 3728.m00061

Description

Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF00880 ) Nebulin repeat
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( PF00009 ) Elongation factor Tu GTP binding
• ( TIGR02528 ) ethanolamine utilization protein, EutP
• ( TIGR00157 ) ribosome small subunit-dependent GTPase A

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 12.7%

TetraMine Data

TTHERM_00540100

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_18212.1	4.99780462713828e-94	Ras family protein (588 aa)
Oxytricha	Contig22470.0.g95	1.9997255150861791e-53	Ras family
DictyBase	DDB_G0286553	5.001531130907917e-44	rab21 on chromosome: 4 positio n 4804109 to 4805424
WormBase	WBGene00004268	7.00174216458014e-43	locus:rab-5 status:Partially _confirmed UniProt:P91857 protein_id:CAB04205.1
SGD	YOR089C	9.99648502569394e-38	VPS21 Rab family GTPase requir ed for endocytic transport and for sorting of vacuolar hydro lases; localized in endocytic intermediates; detected in mit ochondria; geranylgeranylation required for membrane associa tion; mammalian Rab5 homolog
Stentor Coeruleus	SteCoe_10189	1.2995814250075031e-24

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00540100(coding)
ATGAGCAAAGGTACAATGAATAAAATAGTCATTATTGGTGAAGGTAGAGTTGGAAAGACT
TCACTTACATTGAGATATTGCAAAGGAGAATATAGCGATACATAAGAATCTACAATTAAT
GTTTCTTATTTAGAAAAAACAGTCCAAGTAAATGAGACAGATAAAGTTAACATTGCTATT
TGGGATACTGCAGGACAAGAAAAATTCAAATCTATAACTCCTATGTATTACTAGTAAGCT
GTCTGCGCTATTATTGTATATGATATTACTTATAAAGAATCTTTTGATAAGGTTAAATCG
TGGGTTACTGAGCTAACTTAAATTTTAGATACAAATAAGATAGTAATATGTATAGCAGGA
AACAAGTGCGATCTAGAAAATAATAGATAAATTGATAAATAATTTGCAGAAGATTATGCT
AAATCTGTGGGTGCTCGTCATTTCCTTACATCTGCTAAAAACAACAGAGGTATTGATGAA
CTTTTCTAATATGTTGGCTAAGAAATTCTAAAAAGAAATACTAACAAAGGAAAGAAAAAT
AGTAAAATGATTATAAATAATCAATCAATTCTTGAAGGTGATAAAAAGAAAGAAGAAAAA
AAGAAGAAGGACTCTTGCTGTTGA

>TTHERM_00540100(protein)
MSKGTMNKIVIIGEGRVGKTSLTLRYCKGEYSDTQESTINVSYLEKTVQVNETDKVNIAI
WDTAGQEKFKSITPMYYQQAVCAIIVYDITYKESFDKVKSWVTELTQILDTNKIVICIAG
NKCDLENNRQIDKQFAEDYAKSVGARHFLTSAKNNRGIDELFQYVGQEILKRNTNKGKKN
SKMIINNQSILEGDKKKEEKKKKDSCC

>TTHERM_00540100(gene)
ATGAGCAAAGGTACAATGAATAAAATAGTCATTATTGGTGAAGGTAATTATTGCTTTTTA
CTTTTAGAAGATATTCATTAAAATAGTTAAAAACTTTTTTGATATTTCTTGTAAATATTG
AGAAAAAAATATGGATGCTTTTAATCAATCAAACAAAATAATATCTAAAATTGAGAATAT
TTTTATTGGAAAATGTTTAGGTAGAGTTGGAAAGACTTCACTTACATTGAGATATTGCAA
AGGAGAATATAGCGATACATAAGAATCTACAATTAATGTTTCTTATTTAGAAAAAACAGT
CCAAGTAAATGAGACAGATAAAGTTAACATTGCTATTTGGGTAAAAATTATTATTAATAA
TAAAATAGTTTCTGATAAATATTATCTTTAAAATTGCATTATTTTATTTAAAATTTAGTA
TTTGCTAACATAATTTTTTATATAAAAGGATACTGCAGGACAAGAAAAATTCAAATCTAT
AACTCCTATGTATTACTAGTAAGCTGTCTGCGCTATTATTGTATATGATATTACTTATAA
AGAATCTTTTGATAAGGTAAATACAATTAATTATCTTATTTTGAATATATTATACTAATT
TCTCCTATAAAAAAATGATATTTTTCATTCAATTTAGTTTATTTATTTGATCAATTAATG
AAATATAATAGGTTAAATCGTGGGTTACTGAGCTAACTTAAATTTTAGATACAAATAAGA
TAGTAATATGTATAGCAGGAAACAAGTGCGATCTAGAAAATAATAGATAAATTGATAAAT
AATTTGCAGAAGATTATGCTAAATCTGTGGGTGCTCGTCATTTCCTTACATCTGCTAAAA
ACAACAGAGGTATTGATGAACTTTTCTAATATGTTGGCTAAGGTAATAAATAAATAAATA
AATAAATTAATATTATTAAGCTTAATAGTTTGTTGTTTTATAATTTTAATAACATTTTAT
AAAAAAGAAATTCTAAAAAGAAATACTAACAAAGGAAAGAAAAATAGTAAAATGATTATA
AATAATCAATCAATTCTTGAAGGTGATAAAAAGAAAGAAGAAAAAAAGAAGAAGGACTCT
TGCTGTTGA