Identifiers and Description

Gene Model Identifier

TTHERM_00957580

Standard Name

RAB17A (RAB GTPase 17A)

Aliases

PreTt21654 | 177.m00058

Description

Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• intracellular (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00071 ) Ras family
• ( PF08477 ) Miro-like protein
• ( PF01926 ) GTPase of unknown function
• ( PF00025 ) ADP-ribosylation factor family
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR02528 ) ethanolamine utilization protein, EutP

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00957580

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_14072.1	9.999664388307901e-124	Ras family protein (199 aa)
Oxytricha	Contig22448.0.g39	1.0000633497921574e-36	Ras family
SGD	YOR089C	3.00033207980219e-32	VPS21 Rab family GTPase requir ed for endocytic transport and for sorting of vacuolar hydro lases; localized in endocytic intermediates; detected in mit ochondria; geranylgeranylation required for membrane associa tion; mammalian Rab5 homolog
DictyBase	DDB_G0289827	3.999374135750469e-31	rab18 on chromosome: 5 positio n 3292859 to 3293559
WormBase	WBGene00004286	3.0010664139725277e-29	locus:rab-39 status:Partiall y_confirmed UniProt:Q18969 protein_id:CAA87774.2
Stentor Coeruleus	SteCoe_9987	2.1151310375910805e-19

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00957580(coding)
ATGTGTTTCGGATCCAGCTCTAAGAAATAGTAAAGCAAACCCAAGCTTTTAAAGCCCAAG
CAAAGTTAGTACAAAACTAAGCTCATTCTTTTAGGTGACATGAACGTAGGCAAAACTTCA
ATCTGCGAGTATTACAAGAAGAACGTGCCTGCAAAGAACTTGCCAAATACAATTGGTGTC
ACATATTTCGAGTTCGACATCAAACTAGAAAATGGCATTAACGTTCACTTAGATATTTGG
GATACAGCAGGATAAGAAATTTATTAGTCACTACTAAAGATATACTATCAAGATGCTAAC
ATAGTTTTTTTAGTTTTTGATGTGAGTGCAAGATAGACTCTTGAACGTGTTGAGTACTGG
ATTAGCGAACTCAAAGAGCAAGTAGATGATAAAAACCTAAAGTTGGTGTTAATAGGTAAC
AAATGCGACATAGATGCAGATAAGAGGTAAATCAGTCTTGAGCAAGGTCAAGATTTTGCT
AGAAATAAAAACATTCCTTACTTTGAAACTAGTGCAATCACTGGAGAAGGAATAGTTGAA
GTATTCCGCTAAACAGTAAAGGACTATGTGTAATATAAGACAAACGGAGGAAAATGA

>TTHERM_00957580(protein)
MCFGSSSKKQQSKPKLLKPKQSQYKTKLILLGDMNVGKTSICEYYKKNVPAKNLPNTIGV
TYFEFDIKLENGINVHLDIWDTAGQEIYQSLLKIYYQDANIVFLVFDVSARQTLERVEYW
ISELKEQVDDKNLKLVLIGNKCDIDADKRQISLEQGQDFARNKNIPYFETSAITGEGIVE
VFRQTVKDYVQYKTNGGK

>TTHERM_00957580(gene)
ATGTGTTTCGGATCCAGCTCTAAGAAATAGTAAAGCAAACCCAAGCTTTTAAAGCCCAAG
CAAAGTTAGTACAAAACTAAGCTCATTCTTTTAGGTGACATGAACGTAGGCAAAACTTCA
ATCTGCGAGTATTACAAGAAGAACGTGCCTGCAAAGAACTTGCCAAATACAATTGGTGTC
ACATATTTCGAGTTCGACATCAAACTAGAAAATGGCATTAACGTTCACTTAGATATTTGG
GATACAGCAGGATAAGAAATTTATTAGTAAGCCTTTATTTTTTTAGCAATAAGAAGATTC
TTCCCATTTGAATTCTCATTTGACTCGTTCCAATTGAGTTCTGAGTTCTTTCGTTTTTTT
AATATTTTTGTTAACTTTCTTAGAGATTGTCCAGCTAGCTATTCATTCATTTGCATAATA
AATGTTATTAAAGCCAAAAAATAAAATAAAAGCAAAGATAAGAAAAGAAGAACTTGATTT
GGGCAGATTAAATATGTGTTGAATTTATAATGAATTAAATTAAGGTATTTTATTTTGTAA
TATCAATGAATAGGTCACTACTAAAGATATACTATCAAGATGCTAACATAGTTTTTTTAG
TTTTTGATGTGAGTGCAAGATAGACTCTTGAACGTGTTGAGTACTGGATTAGCGAACTCA
AAGAGCAAGTAGATGATAAAAACCTAAAGTTGGTGTTAATAGGTAACAAATGCGACATAG
ATGCAGATAAGAGGTAAATCAGTCTTGAGCAAGGTCAAGATTTTGCTAGAAATAAAAACA
TTCCTTACTTTGAAACTAGTGCAATCACTGGAGAAGGAATAGTTGAAGTATTCCGCTAAA
CAGTAAAGGACTATGTGTAATATAAGACAAACGGAGGAAAATGA